Výsledky vyhľadávania - "CYCLIC nucleotide-gated ion channels"

Extracellular salt bridge networks around S4 implicated in HCN channel gating and heart disease.

Autori: Ryu, Kaei Kasuya, Go Nakajo, Koichi

Zdroj: Proceedings of the National Academy of Sciences of the United States of America. 9/16/2025, Vol. 122 Issue 37, p1-10. 10p.

Predmety: *HEART diseases, *CYCLIC nucleotide-gated ion channels, *CARDIAC pacing, *IONIC interactions, *ELECTRIC potential measurement

Pharmacological Targeting of Hyperpolarization‐Activated Cyclic Nucleotide‐Gated Cation Channels on Bladder Afferent Sensory Transmission.

Autori: Woon, Eric Santeli, Jorge Villalobos Liu, Jia a ďalší

Zdroj: LUTS (1757-5664). Sep2025, Vol. 17 Issue 5, p1-10. 10p.

Predmety: *CYCLIC nucleotide-gated ion channels, *IVABRADINE, *CESIUM, *ISOPROTERENOL, *TARGETED drug delivery, *BLADDER

Domain coupling in allosteric regulation of SthK measured using time-resolved transition metal ion FRET.

Autori: Eggan, Pierce Gordon, Sharona E. Zagotta, William N.

Zdroj: eLife. 8/12/2025, p1-22. 22p.

Predmety: *ALLOSTERIC regulation, *CYCLIC nucleotide-gated ion channels, *PROTEIN domains, *MOLECULAR dynamics, *LIGAND binding (Biochemistry), *BIOENERGETICS, *FLUORESCENCE resonance energy transfer, *TRANSMEMBRANE domains

A comprehensive review of HCN channel expression and Ih in the auditory system: then, now, and future perspectives.

Autori: Ordiway, George McLellan, Kristine Sanchez, Jason Tait

Zdroj: Journal of Neurophysiology. Aug2025, Vol. 134 Issue 2, p458-470. 13p.

Predmety: *CYCLIC nucleotide-gated ion channels, *ION channels, *AUDITORY pathways, *ACTION potentials, *AUDITORY perception, *ACOUSTIC signal processing

Characterization of a rhodopsin-phosphodiesterase from Choanoeca flexa to be combined with rhodopsin-cyclases for bidirectional optogenetic cGMP control.

Autori: Liem, Nicolas Spreen, Anika Silapētere, Arita a ďalší

Zdroj: Journal of Biological Chemistry. Apr2025, Vol. 301 Issue 4, p1-11. 11p.

Predmety: *CYCLIC nucleotide-gated ion channels, *CYCLIC nucleotides, *PHOSPHODIESTERASES, *RHODOPSIN, *RESEARCH personnel, *ION channels

HCN2 deficiency correlates with memory deficits and hyperexcitability of dCA1 pyramidal neurons in Alzheimer's disease.

Autori: Zhang, Xiaoqin Zhang, Yiping Zhang, Ting a ďalší

Zdroj: Alzheimer's Research & Therapy. 2/27/2025, Vol. 17 Issue 1, p1-20. 20p.

Predmety: *CYCLIC nucleotide-gated ion channels, *PYRAMIDAL neurons, *ALZHEIMER'S disease, *NEURAL circuitry, *IMMUNOSTAINING

Analysis of CNGC Family Members in Citrus clementina (Hort. ex Tan.) by a Genome-Wide Approach.

Autori: Lv, Yuanda Liu, Shumei Ma, Yanyan a ďalší

Zdroj: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 3, p960. 21p.

Predmety: *CYCLIC nucleotide-gated ion channels, *PHYTOPHTHORA nicotianae, *PLANT hormones, *GENE families, *ABIOTIC stress

Aberrant HCN4 channel expression: Impacts on neuronal excitability and implications for epilepsy pathogenesis.

Autori: Spyrou, James Escobar, Iris Bordey, Angélique a ďalší

Zdroj: British Journal of Pharmacology; Dec2025, Vol. 182 Issue 23, p5693-5705, 13p

Predmety: EPILEPSY, SEIZURES (Medicine), ACTION potentials, CYCLIC nucleotide-gated ion channels, THERAPEUTICS, NEURONS, FOCAL cortical dysplasia

Structural mechanisms of assembly, gating, and calmodulin modulation of human olfactory CNG channel.

Autori: Xue, Jing Gan, Ninghai Zeng, Weizhong a ďalší

Zdroj: Nature Communications; 10/23/2025, Vol. 16 Issue 1, p1-12, 12p

Predmety: CYCLIC nucleotide-gated ion channels, CALMODULIN, CELLULAR signal transduction, ELECTRON cryomicroscopy, OLFACTORY cortex, CELL communication, PROTEIN subunits

Calcium signaling triggers early high humidity responses in Arabidopsis thaliana.

Autori: Hussain, Saad Hiraku Suda Nguyen, Christine H. a ďalší

Zdroj: Proceedings of the National Academy of Sciences of the United States of America. 12/17/2024, Vol. 121 Issue 51, p1-8. 27p.

Predmety: *CYCLIC nucleotide-gated ion channels, *HUMIDITY, *ABSCISIC acid, *ARABIDOPSIS thaliana, *TRANSCRIPTION factors

Ligand-coupled conformational changes in a cyclic nucleotide-gated ion channel revealed by time-resolved transition metal ion FRET.

Autori: Eggan, Pierce Gordon, Sharona E. Zagotta, William N.

Zdroj: eLife. 12/10/2024, p1-24. 24p.

Predmety: *CYCLIC nucleotide-gated ion channels, *FLUORESCENCE resonance energy transfer, *TRANSITION metal ions, *ALLOSTERIC regulation, *IONIC structure, *ION channels

Genome Analysis of BnCNGC Gene Family and Function Exploration of BnCNGC57 in Brassica napus L.

Autori: Wang, Yue Chi, Qing Jia, Wenjing a ďalší

Zdroj: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 21, p11359. 19p.

Predmety: *CYCLIC nucleotide-gated ion channels, *BOTANY, *RAPESEED, *SEED size, *GENE families, *ION channels

Genome-Wide Identification of the Cyclic Nucleotide-Gated Ion Channel Gene Family and Expression Profiles Under Low-Temperature Stress in Luffa cylindrica L.

Autori: Liu, Jianting Wang, Yuqian Peng, Lijuan a ďalší

Zdroj: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11330. 16p.

Predmety: *CYCLIC nucleotide-gated ion channels, *MEMBRANE proteins, *LUFFA aegyptiaca, *GENE families, *CALCIUM channels

Inhibition of HCN Channels Enhances Oxidative Stress and Autophagy of NRK-52E Cells Under NH 4 Cl Treatment.

Autori: López-González, Zinaeli Escobar, Laura I. León-Aparicio, Daniel a ďalší

Zdroj: International Journal of Molecular Sciences; Sep2025, Vol. 26 Issue 18, p9227, 18p

Predmety: OXIDATIVE stress, AUTOPHAGY, AMMONIUM chloride, KIDNEY cell culture, ACIDOSIS, LYSOSOMES, REACTIVE oxygen species, CYCLIC nucleotide-gated ion channels

The cyclic nucleotide-gated channels CNGC2 and CNGC4 support systemic wound responses in Arabidopsis thaliana.

Autori: Johns, Sarah Wiegman, Erin Bakshi, Arkadipta a ďalší

Zdroj: Frontiers in Plant Science; 2025, p1-15, 16p

Predmety: CYCLIC nucleotide-gated ion channels, ARABIDOPSIS thaliana, PLANT cellular signal transduction, PLANT injuries, PLANT defenses, INTRACELLULAR calcium

Transgenic mice overexpressing Pitx2 in the atria develop tachycardia-bradycardia syndrome.

Autori: Baba, Shunsuke Shinjo, Satoko Seya, Daiki a ďalší

Zdroj: PLoS ONE; 9/4/2025, Vol. 20 Issue 9, p1-19, 19p

Predmety: TACHYCARDIA, SINOATRIAL node, ELECTROPHYSIOLOGY, HEART beat, ATRIAL fibrillation, TRANSGENIC mice, CYCLIC nucleotide-gated ion channels, TRANSCRIPTION factors

HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models.

Autori: Houdayer, Clara Phillips, A. Marie Chabbert, Marie a ďalší

Zdroj: Annals of Neurology; Sep2025, Vol. 98 Issue 3, p573-589, 17p

Predmety: INTELLECTUAL disabilities, DEVELOPMENTAL delay, EPILEPSY, FUNCTIONAL assessment, NEURAL development, GENETIC mutation, CYCLIC nucleotide-gated ion channels, CELL culture

A comprehensive review of HCN channel expression and Ih in the auditory system: then, now, and future perspectives.

Autori: Ordiway, George McLellan, Kristine Sanchez, Jason Tait

Zdroj: Journal of Neurophysiology; Aug2025, Vol. 134 Issue 2, p458-470, 13p

Predmety: CYCLIC nucleotide-gated ion channels, ION channels, AUDITORY pathways, ACTION potentials, AUDITORY perception, ACOUSTIC signal processing

Genome-wide identification of cyclic nucleotide-gated channel gene family in Solanum tuberosum and silencing of StCNGC2 provides resistance to Pectobacterium carotovorum.

Autori: Sun, Kaile Liu, Shuai Mao, Huipo a ďalší

Zdroj: Frontiers in Plant Science; 2025, p1-14, 84p

Predmety: CYCLIC nucleotide-gated ion channels, PLANT defenses, GENE silencing, POTATOES, PLANT diseases

Whole exome sequencing reveals pathogenic variants in CNGA3, CACNA1F, and RPGRIP1 in consanguineous Pakistani families with diverse retinal phenotypes.

Autori: Tareen, Jahangir Khan Khan, Hamid Ghani, Shamsul a ďalší

Zdroj: PLoS ONE; 7/30/2025, Vol. 20 Issue 7, p1-15, 15p

Predmety: RETINAL diseases, GENETIC mutation, CALCIUM channels, CYCLIC nucleotide-gated ion channels, NUCLEOTIDE sequencing, GENE families

Geografický termín: PAKISTAN