Výsledky vyhľadávania - "CXCR4/metabolism"

A Prospective Evaluation of Chemokine Receptor-4 (CXCR4) Overexpression in High-grade Glioma Using 68Ga-Pentixafor (Pars-Cixafor™) PET/CT Imaging

Autori: Dadgar, Habibollah Norouzbeigi, Nasim Assadi, Majid a ďalší

Zdroj: Academic Radiology. 32:2247-2256

Predmety: Male, Adult, PET/CT, CXCR4/metabolism, Gallium Radioisotopes, Ga-Pentixafor, GBM, Coordination Complexes, Glioma/diagnostic imaging, Receptors, Humans, Prospective Studies, Retrospective Studies, Aged, CXCR4, Cyclic, 616.0757, (68)Ga-Pentixafor, Middle Aged, Magnetic Resonance Imaging, Brain Neoplasms/diagnostic imaging, Feasibility Studies, Female, Neoplasm Grading, Radiopharmaceuticals, Peptides, Positron Emission Tomography Computed Tomography/methods, MRI

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39690071
https://hdl.handle.net/11370/6f871c1c-9187-49cc-b5a9-45cb3a73199a
https://doi.org/10.1016/j.acra.2024.11.064
https://research.rug.nl/en/publications/6f871c1c-9187-49cc-b5a9-45cb3a73199a

CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells

Autori: Yan Wang Ursula Rambold Petra Fiedler a ďalší

Zdroj: Cell Mol Immunol

Predmety: 631/250/2152/2153/1982, Cell Proliferation [MeSH], Mice, Inbred C57BL [MeSH], B-Lymphocytes/immunology [MeSH], Plasma Cells/immunology [MeSH], T Follicular Helper Cells/immunology [MeSH], CD30L, Cell Differentiation [MeSH], Animals [MeSH], Germinal Center/immunology [MeSH], Lymphocyte Activation [MeSH], Senescence associated T cells (SAT cells), Immunoglobulin G/immunology [MeSH], Mice [MeSH], Article, B lymphocytes, Ki-1 Antigen/metabolism [MeSH], CD30, Germinal center reaction, 631/250/1619/40, Conditional mice, Immunoglobulin Class Switching [MeSH], Receptors, CXCR4/metabolism [MeSH], article, B-Lymphocytes, Receptors, CXCR4, T Follicular Helper Cells, Plasma Cells, Ki-1 Antigen, Cell Differentiation, Germinal Center, Lymphocyte Activation, Immunoglobulin Class Switching, Mice, Inbred C57BL, Mice, Immunoglobulin G, Animals, Cell Proliferation

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39420111
https://repository.publisso.de/resource/frl:6492539

Interobserver Agreement Rates on CXCR4-Directed PET/CT in Patients with Marginal Zone Lymphoma

Autori: Werner, Rudolf A. Zhi, Yingjun Dreher, Niklas a ďalší

Zdroj: Mol Imaging Biol

Predmety: Male, Observer Variation, Adult, Aged, 80 and over, ddc:610, Receptors, CXCR4, Lymphoma, B-Cell, Marginal Zone, Middle Aged, Chemokine receptor, Female [MeSH], Aged, 80 and over [MeSH], Observer Variation [MeSH], Aged [MeSH], Adult [MeSH], Lymphoma, B-Cell, Marginal Zone/diagnostic imaging [MeSH], Humans [MeSH], Theranostics, Middle Aged [MeSH], Male [MeSH], C-X-C motif chemokine receptor 4, Marginal zone lymphoma, Lymphoma, B-Cell, Marginal Zone/pathology [MeSH], Positron Emission Tomography Computed Tomography/methods [MeSH], Research Article, CXCR4, Receptors, CXCR4/metabolism [MeSH], 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Positron Emission Tomography Computed Tomography, Humans, Female, Aged

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39090381
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/115064
https://opus.bibliothek.uni-augsburg.de/opus4/files/115064/115064.pdf
https://nbn-resolving.org/urn:nbn:de:bvb:384-opus4-1150645
https://doi.org/10.1007/s11307-024-01940-y
https://repository.publisso.de/resource/frl:6523690
https://opus.bibliothek.uni-wuerzburg.de/files/39848/11307_2024_Article_1940.pdf
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/39848
https://doi.org/10.1007/s11307-024-01940-y
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-398480

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms

Autori: Simon Mobach Nick D. Bergkamp Ziliang Ma a ďalší

Zdroj: Proceedings of the National Academy of Sciences. 122

Predmety: CXCR4, Tumor, Leukemia, Carcinogenesis, receptor oligomerization, leukemia, CXCR4/metabolism, Cell Movement/drug effects, drug sensitization, Molecular Processes and Therapies [Topic 2], Lymphocytic, Cell Line, SDG 3 - Good Health and Well-being, Cardiovascular and Metabolic Diseases, B-Cell/metabolism, Receptors, Humans, Chronic, Protein Multimerization, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://edoc.mdc-berlin.de/id/eprint/25432/2/25432suppl.pdf

Predictive value of C-X-C motif chemokine receptor 4-directed molecular imaging in patients with advanced adrenocortical carcinoma

Autori: Wiebke Schloetelburg Philipp E. Hartrampf Aleksander Kosmala a ďalší

Zdroj: Eur J Nucl Med Mol Imaging

Predmety: Male, Adult, ddc:610, Receptors, CXCR4, Middle Aged, Adrenal Cortex Neoplasms/pathology [MeSH], Female [MeSH], Aged [MeSH], Adult [MeSH], Humans [MeSH], Adrenocortical Carcinoma/diagnostic imaging [MeSH], Adrenal Cortex Neoplasms/metabolism [MeSH], Positron Emission Tomography Computed Tomography [MeSH], Peptides, Cyclic [MeSH], Predictive Value of Tests [MeSH], Middle Aged [MeSH], Adrenocortical Carcinoma/pathology [MeSH], Original Article, Adrenal Cortex Neoplasms/diagnostic imaging [MeSH], Male [MeSH], Prognosis [MeSH], Adrenocortical Carcinoma/metabolism [MeSH], Receptors, CXCR4/metabolism [MeSH], Coordination Complexes [MeSH], Prognosis, Peptides, Cyclic, Adrenal Cortex Neoplasms, 03 medical and health sciences, 0302 clinical medicine, Coordination Complexes, Predictive Value of Tests, Positron Emission Tomography Computed Tomography, Adrenocortical Carcinoma, Humans, Female, Aged

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38896128
https://repository.publisso.de/resource/frl:6520429
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/39213
https://doi.org/10.1007/s00259-024-06800-z
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-392131
https://opus.bibliothek.uni-wuerzburg.de/files/39213/00259_2024_Article_6800.pdf

Targeting CXCR4/CXCL12 axis via [177Lu]Lu-DOTAGA.(SA.FAPi)2 with CXCR4 antagonist in triple-negative breast cancer

Autori: Guangfa Bao Ziqiang Wang Luoxia Liu a ďalší

Zdroj: Eur J Nucl Med Mol Imaging

Predmety: 0301 basic medicine, Receptors, CXCR4, Benzylamines, 0303 health sciences, Triple Negative Breast Neoplasms/drug therapy [MeSH], Cell Line, Tumor [MeSH], Receptors, CXCR4/antagonists, Triple-negative breast cancer (TNBC), Triple Negative Breast Neoplasms/radiotherapy [MeSH], Serine Endopeptidases/metabolism [MeSH], Radiopharmaceuticals/pharmacology [MeSH], Cyclams/pharmacology [MeSH], Original Article, Heterocyclic Compounds/pharmacology [MeSH], Membrane Proteins/metabolism [MeSH], CXCR4 antagonist, Cyclams/therapeutic use [MeSH], CXCR4/CXCL12, [, Chemokine CXCL12/metabolism [MeSH], Receptors, CXCR4/metabolism [MeSH], Lutetium [MeSH], Female [MeSH], Gelatinases/metabolism [MeSH], Humans [MeSH], Animals [MeSH], Triple Negative Breast Neoplasms/diagnostic imaging [MeSH], Heterocyclic Compounds/chemistry [MeSH], Endopeptidases [MeSH], Benzylamines/pharmacology [MeSH], Mice [MeSH], Cell Proliferation/drug effects [MeSH], Radiopharmaceuticals/therapeutic use [MeSH], Serine Endopeptidases, Membrane Proteins, Triple Negative Breast Neoplasms, Lutetium, Cyclams, Chemokine CXCL12, Mice, 03 medical and health sciences, Heterocyclic Compounds, Gelatinases, Cell Line, Tumor, Endopeptidases, Animals, Humans, Female, Radiopharmaceuticals, Cell Proliferation

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38587644
https://repository.publisso.de/resource/frl:6521149

Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes

Autori: Kai He Xue Dong Tianjing Yang a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-25 (2025)
He, K, Dong, X, Yang, T, Li, Z, Liu, Y, He, J, Wu, M, Wei-Zhang, S, Kaysar, P, Cui, B, Yao, X, Zhang, L, Zhou, W, Xu, H, Wei, J, Liu, Q, Hu, J, Wang, X & Yan, H 2025, 'Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes', Nature Communications, vol. 16, 2821. https://doi.org/10.1038/s41467-025-58074-0

Predmety: Male, Receptors, CXCR4, Science, Macular Degeneration/metabolism, Receptors, CXCR4/metabolism, Nerve Tissue Proteins/metabolism, Antigens, CD/metabolism, Choroidal Neovascularization/metabolism, Receptors, Cell Surface, Nerve Tissue Proteins, Semaphorins, CD8-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes/immunology, Article, Macular Degeneration, Mice, Antigens, CD, Chemokine CXCL12/metabolism, Smoking/adverse effects, Animals, Humans, Phosphorylation, Receptors, Cell Surface/metabolism, Smoking, Choroidal Neovascularization, Chemokine CXCL12, Mice, Inbred C57BL, Disease Models, Animal, Pericytes/metabolism, Semaphorins/metabolism, Female, Pericytes, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40121188
https://doaj.org/article/18ed61d913b34fd1b61e6cdd0245998e
https://pure.qub.ac.uk/en/publications/9c81c57b-65d2-4a97-8ce2-79af12519159

An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

Autori: Omar El Bounkari Chunfang Zan Bishan Yang a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-30 (2025)
Nature Communications 16(1), 2297 (2025). doi:10.1038/s41467-025-57540-z

Predmety: Male, CXCR4 protein, mouse, Hepatocytes/metabolism pathology, Mice, Knockout, ApoE, pathology [Atherosclerosis], Foam Cells/metabolism, Inbred C57BL, metabolism [Macrophage Migration-Inhibitory Factors], Mice, Receptors, Macrophage Migration-Inhibitory Factors/metabolism genetics, metabolism [Atherosclerosis], metabolism [Intramolecular Oxidoreductases], Mice, Knockout, Liver/metabolism pathology, metabolism [Hepatocytes], pathology [Hepatocytes], Atherosclerosis/metabolism pathology genetics, pathology [Liver], Chemokines/metabolism, Intramolecular Oxidoreductases, Lipogenesis/genetics, Liver, genetics [Intramolecular Oxidoreductases], Female, ddc:500, Chemokines, Signal Transduction, Receptors, CXCR4, genetics [Lipogenesis], Knockout, Science, genetics [Atherosclerosis], CXCR4/metabolism genetics, Article, Apolipoproteins E, Animals, Humans, metabolism [Foam Cells], dopachrome isomerase, Macrophage Migration-Inhibitory Factors, Lipogenesis, Histocompatibility Antigens Class II, metabolism [Chemokines], Atherosclerosis, genetics [Receptors, CXCR4], Mice, Inbred C57BL, Antigens, Differentiation, B-Lymphocyte, Intramolecular Oxidoreductases/metabolism genetics, Hepatocytes, genetics [Macrophage Migration-Inhibitory Factors], metabolism [Receptors, CXCR4], metabolism [Liver]

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40055309
https://doaj.org/article/2ff6fa1b0e5446128b7aaba1c3129142
https://epub.ub.uni-muenchen.de/124912/

CXCR4-directed PET/CT with [68 Ga]Ga-pentixafor in solid tumors—a comprehensive analysis of imaging findings and comparison with histopathology

Autori: Niklas Dreher Stefanie Hahner Carmina T. Fuß a ďalší

Zdroj: Eur J Nucl Med Mol Imaging

Predmety: ddc:610, 03 medical and health sciences, Receptors, CXCR4, 0302 clinical medicine, Coordination Complexes, Positron Emission Tomography Computed Tomography, Neoplasms, Humans, Original Article, Gallium Radioisotopes, PET/CT, Humans [MeSH], Radioligand therapy, Theranostics, Peptides, Cyclic [MeSH], Solid tumors, Neoplasms/diagnostic imaging [MeSH], Gallium Radioisotopes [MeSH], C-X-C motif chemokine receptor 4, Positron Emission Tomography Computed Tomography/methods [MeSH], [, CXCR4, Receptors, CXCR4/metabolism [MeSH], Coordination Complexes [MeSH], Peptides, Cyclic, 3. Good health

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38082196
https://repository.publisso.de/resource/frl:6508689
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-382254
https://doi.org/10.1007/s00259-023-06547-z
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/38225
https://opus.bibliothek.uni-wuerzburg.de/files/38225/s00259-023-06547-z.pdf

Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability

Autori: Mirja Harms Rikke Fabech Hansson Andrea Gilg a ďalší

Zdroj: J Med Chem
Harms, M, Fabech Hansson, R, Gilg, A, Almeida-Hernández, Y, Löffler, J, Rodríguez-Alfonso, A, Habib, M M W, Albers, D, Ahmed, N S, Abadi, A H, Winter, G, Rasche, V, Beer, A J, Weidinger, G, Preising, N, Ständker, L, Wiese, S, Sanchez-Garcia, E, Zelikin, A N & Münch, J 2023, 'Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability', Journal of Medicinal Chemistry, vol. 66, no. 22, pp. 15189-15204. https://doi.org/10.1021/acs.jmedchem.3c01128

Predmety: HIV-1/metabolism, Receptors, CXCR4, Receptors, CXCR4/metabolism, HIV Infections, Peptides/chemistry, 3. Good health, Albumins, Amines/metabolism, HIV-1, Humans, Amines, Peptides, Albumins/metabolism, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37940118
https://pure.au.dk/ws/files/417992209/harms-et-al-2023-development-of-n-terminally-modified-variants-of-the-cxcr4-antagonistic-peptide-epi-x4-for-enhanced.pdf
https://pure.au.dk/ws/files/417992209/harms-et-al-2023-development-of-n-terminally-modified-variants-of-the-cxcr4-antagonistic-peptide-epi-x4-for-enhanced.pdf
https://pure.au.dk/portal/en/publications/6bc1de54-22d8-4206-bffa-ad026fed2972
http://www.scopus.com/inward/record.url?scp=85178384547&partnerID=8YFLogxK
https://doi.org/10.1021/acs.jmedchem.3c01128

Inducible CXCL12/CXCR4-dependent extramedullary hematopoietic niches in the adrenal gland

Autori: Vijaykumar, A. Sordet-Dessimoz, J. Gebhard, S. a ďalší

Zdroj: Blood, vol. 144, no. 9, pp. 964-976

Predmety: Animals, Receptors, CXCR4/metabolism, Receptors, CXCR4/genetics, Chemokine CXCL12/metabolism, Mice, Hematopoietic Stem Cells/metabolism, Hematopoietic Stem Cells/pathology, Adrenal Glands/metabolism, Adrenal Glands/pathology, Stem Cell Niche, Mice, Inbred C57BL, Humans, Receptor, Platelet-Derived Growth Factor alpha/metabolism, Receptor, Platelet-Derived Growth Factor alpha/genetics, Receptors, Leptin/metabolism, Receptors, Leptin/genetics, Hematopoiesis, Extramedullary, Splenectomy, Mice, Transgenic

Popis súboru: application/pdf

Prístupová URL adresa: https://serval.unil.ch/notice/serval:BIB_608A40306195
https://serval.unil.ch/resource/serval:BIB_608A40306195.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_608A403061951

Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis

Autori: Miaomiao Zhang Jinghao Zhang Haisheng Hu a ďalší

Zdroj: J Transl Med
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)

Predmety: Male, 0301 basic medicine, Receptors, CXCR4, 0303 health sciences, Research, Gene Expression Profiling, Idiopathic pulmonary fibrosis, Multiomic, Middle Aged, Idiopathic Pulmonary Fibrosis, Monocytes, Monocyte-derived alveolar macrophages, 03 medical and health sciences, Phenotype, Gene Expression Regulation, Lung/pathology [MeSH], Female [MeSH], Humans [MeSH], Middle Aged [MeSH], Lung/metabolism [MeSH], Receptors, CXCR4/genetics [MeSH], Transcription factors, Fibrosis, Idiopathic Pulmonary Fibrosis/metabolism [MeSH], Idiopathic Pulmonary Fibrosis/pathology [MeSH], Monocytes/metabolism [MeSH], Idiopathic Pulmonary Fibrosis/genetics [MeSH], Male [MeSH], Phenotype [MeSH], Gene Expression Profiling [MeSH], Gene Expression Regulation [MeSH], Macrophages, Alveolar/pathology [MeSH], Receptors, CXCR4/metabolism [MeSH], Macrophages, Alveolar/metabolism [MeSH], Macrophages, Alveolar, Medicine, Humans, Female, Lung

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38937806
https://doaj.org/article/c5f5488bceb24197a6340d4916cc48b8
https://repository.publisso.de/resource/frl:6502874

Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability

Autori: Mirja Harms Rikke Fabech Hansson Sheiliza Carmali a ďalší

Zdroj: Harms, M, Hansson, R F, Carmali, S, Almeida-Hernández, Y, Sanchez-Garcia, E, Münch, J & Zelikin, A N 2022, 'Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability', Bioconjugate Chemistry, vol. 33, no. 4, pp. 594-607. https://doi.org/10.1021/acs.bioconjchem.2c00034

Predmety: CXCR4, 0301 basic medicine, Receptors, CXCR4, 0303 health sciences, RECEPTOR, Receptors, CXCR4/metabolism, HIV Infections, ALBUMIN, HIV-1 ENTRY, Peptides/chemistry, CHEMOKINE, SMALL-MOLECULE, 3. Good health, POLYVINYL-ALCOHOL, 03 medical and health sciences, DESIGN, DISCOVERY, HIV-1/physiology, HIV-1, Humans, DRUG-DELIVERY, Peptides, Biologie, Dimerization, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35293739
https://pure.au.dk/portal/en/publications/c256ed21-8949-4e1e-a7f9-1934fb06a23a
https://doi.org/10.1021/acs.bioconjchem.2c00034
http://www.scopus.com/inward/record.url?scp=85127436396&partnerID=8YFLogxK
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85127436396
https://www.ncbi.nlm.nih.gov/pubmed/35293739
https://doi.org/10.1021/acs.bioconjchem.2c00034

CTC-derived pancreatic cancer models serve as research tools and are suitable for precision medicine approaches

Autori: Tang, Jiajia Zheng, Quan Wang, Qi a ďalší

Zdroj: Tang , J , Zheng , Q , Wang , Q , Zhao , Y , Ananthanarayanan , P , Reina , C , Šabanović , B , Jiang , K , Yang , M-H , Meny , C C , Wang , H , Agerbaek , M Ø , Clausen , T M , Gustavsson , T , Wen , C , Borghi , F , Mellano , A , Fenocchio , E , Gregorc , V , Sapino , A , Theander , T G , Fu , D , Aicher , A , Salanti , A ....

Predmety: Humans, Precision Medicine/methods, Pancreatic Neoplasms/pathology, Neoplastic Cells, Circulating/pathology, Carcinoma, Pancreatic Ductal/pathology, Animals, Cell Line, Tumor, Neoplastic Stem Cells/metabolism, Mice, Female, Male, Stearoyl-CoA Desaturase/metabolism, Receptors, CXCR4/metabolism, Middle Aged, Aged, Biomarkers, Tumor/metabolism

Popis súboru: text/html

Dostupnosť: https://researchprofiles.ku.dk/da/publications/91b490c4-cf57-4b77-b0a4-99f82ad1fc23
https://doi.org/10.1016/j.xcrm.2024.101692
https://curis.ku.dk/ws/files/412332155/CTC_derived_pancreatic.htm

CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness

Autori: Stefan Habringer Karl Balabanian Katja Steiger a ďalší

Zdroj: Leukemia

Predmety: Article, B-cell lymphoma, Cancer models, Oncogenes, Oncogenesis, Male, 0301 basic medicine, Cancer Research, Receptors, CXCR4, Disease Progression [MeSH], Cell Cycle Proteins/genetics [MeSH], Mice, Inbred C57BL [MeSH], Leukemia, Lymphocytic, Chronic, B-Cell/metabolism [MeSH], Receptors, CXCR4/genetics [MeSH], Forkhead Box Protein M1/metabolism [MeSH], Forkhead Box Protein M1/genetics [MeSH], Leukemia, Lymphocytic, Chronic, B-Cell/pathology [MeSH], Male [MeSH], Proto-Oncogene Proteins/physiology [MeSH], Receptors, CXCR4/metabolism [MeSH], Gene Expression Regulation, Leukemic [MeSH], Female [MeSH], Mutation [MeSH], Protein Serine-Threonine Kinases/genetics [MeSH], Animals [MeSH], Mice, Knockout [MeSH], Mice [MeSH], Leukemia, Lymphocytic, Chronic, B-Cell/genetics [MeSH], Proto-Oncogene Proteins/metabolism [MeSH], Proto-Oncogene Proteins/genetics [MeSH], Cell Cycle Proteins/metabolism [MeSH], Protein Serine-Threonine Kinases/metabolism [MeSH], CXCR4 hyperactivation, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Polo-Like Kinase 1, Mice, 03 medical and health sciences, Proto-Oncogene Proteins, Animals, CLL development, Mice, Knockout, 0303 health sciences, Gene Expression Regulation, Leukemic, TCL1, Forkhead Box Protein M1, Leukemia, Lymphocytic, Chronic, B-Cell, ddc, Mice, Inbred C57BL, Mutation, Disease Progression, Integrative Biomedicine [Topic 3], Female, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

Popis súboru: application/pdf

Prístupová URL adresa: https://www.nature.com/articles/s41375-021-01376-1.pdf
https://pubmed.ncbi.nlm.nih.gov/34363012
https://www.zora.uzh.ch/id/eprint/207447/1/s41375-021-01376-1.pdf
https://mediatum.ub.tum.de/1621794
https://www.nature.com/articles/s41375-021-01376-1.pdf
https://www.nature.com/articles/s41375-021-01376-1
https://pubmed.ncbi.nlm.nih.gov/34363012/
https://www.zora.uzh.ch/id/eprint/207447/
https://edoc.mdc-berlin.de/id/eprint/20820/1/20820oa.pdf
https://repository.publisso.de/resource/frl:6443800
https://mediatum.ub.tum.de/1704448

CXCR4 in Waldenström’s Macroglobulinema: chances and challenges

Autori: Lisa Marie Kaiser Zachary R. Hunter Steven P. Treon a ďalší

Zdroj: Leukemia

Predmety: 0301 basic medicine, Receptors, CXCR4, 03 medical and health sciences, 0302 clinical medicine, Agammaglobulinaemia Tyrosine Kinase, Animals, Humans, Review Article, Waldenstrom Macroglobulinemia, Waldenstrom Macroglobulinemia/pathology [MeSH], Humans [MeSH], B-cell lymphoma, Signal Transduction [MeSH], Waldenstrom Macroglobulinemia/metabolism [MeSH], Animals [MeSH], Receptors, CXCR4/metabolism [MeSH], Agammaglobulinaemia Tyrosine Kinase/metabolism [MeSH], Signal Transduction, 3. Good health

Prístupová URL adresa: https://www.nature.com/articles/s41375-020-01102-3.pdf
https://pubmed.ncbi.nlm.nih.gov/33273682
https://www.scilit.net/article/5eee5368c580b20568a46422d55b9d08?action=show-references
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862063
https://www.nature.com/articles/s41375-020-01102-3
https://pubmed.ncbi.nlm.nih.gov/33273682/
https://khepri-node.dev.meta-infra.org/papers/cxcr4-in-waldenstroms-macroglobulinema-chances/33273682
https://www.nature.com/articles/s41375-020-01102-3.pdf
https://repository.publisso.de/resource/frl:6471030

How to distinguish between different cell lineages sharing common markers using combinations of double in-situ-hybridization and immunostaining in avian embryos: CXCR4-positive mesodermal and neural crest-derived cells

Autori: Imadeldin Yahya Marion Böing Beate Brand-Saberi a ďalší

Zdroj: Histochem Cell Biol

Predmety: 0301 basic medicine, Original Paper, Receptors, CXCR4, 0303 health sciences, Neural Crest/cytology [MeSH], Chicken embryo, Chickens [MeSH], Mesoderm/metabolism [MeSH], Neural Crest/metabolism [MeSH], NCCs, Double whole-mount ISH, Animals [MeSH], Immunostaining, Immunohistochemistry [MeSH], In Situ Hybridization [MeSH], Receptors, CXCR4/analysis [MeSH], Mesodermal cells, Biomarkers/metabolism [MeSH], Chick Embryo [MeSH], Cell Lineage [MeSH], Biomarkers/analysis [MeSH], Mesoderm/cytology [MeSH], CXCR4, Receptors, CXCR4/metabolism [MeSH], Chick Embryo, Immunohistochemistry, Mesoderm, 03 medical and health sciences, Neural Crest, Animals, Cell Lineage, 10. No inequality, Chickens, Biomarkers, In Situ Hybridization

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00418-020-01920-7.pdf
https://pubmed.ncbi.nlm.nih.gov/33037504
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847855
https://link.springer.com/content/pdf/10.1007/s00418-020-01920-7.pdf
https://europepmc.org/article/PMC/PMC7847855
https://link.springer.com/article/10.1007/s00418-020-01920-7
https://repository.publisso.de/resource/frl:6467566

Doxorubicin upregulates CXCR4 via miR-200c/ZEB1-dependent mechanism in human cardiac mesenchymal progenitor cells.

Autori: Beji, S. Milano, G. Scopece, A. a ďalší

Predmety: Animals, Doxorubicin/pharmacology, Female, Humans, Mesenchymal Stromal Cells/drug effects, Mesenchymal Stromal Cells/metabolism, Mice, Inbred C57BL, MicroRNAs/genetics, MicroRNAs/metabolism, Receptors, CXCR4/genetics, CXCR4/metabolism, Signal Transduction, Up-Regulation/drug effects, Zinc Finger E-box-Binding Homeobox 1/genetics, Zinc Finger E-box-Binding Homeobox 1/metabolism

Popis súboru: application/pdf

Relation: Cell Death & Disease; https://iris.unil.ch/handle/iris/66799; serval:BIB_38337628DC5D; 000409550500058

Dostupnosť: https://iris.unil.ch/handle/iris/66799
https://doi.org/10.1038/cddis.2017.409

[99mTc]-PentixaTec SPECT/CT for Imaging of Chemokine Receptor 4 Expression After Myocardial Infarction.

Autori: Liebich, A. Bundschuh, R.A. Pfob, C.H. a ďalší

Predmety: Humans, Myocardial Infarction/metabolism, Myocardial Infarction/diagnostic imaging, Retrospective Studies, Receptors, CXCR4/metabolism, Male, Radiopharmaceuticals, Female, Single Photon Emission Computed Tomography Computed Tomography/methods, Middle Aged, Aged, Myocardium/metabolism, Myocardium/pathology, Organotechnetium Compounds, Myocardial Perfusion Imaging/methods, Predictive Value of Tests, Coronary Angiography/methods, Up-Regulation, diagnostic imaging, myocardial infarction, myocytes, cardiac, stroke volume, ventricular function, left

Relation: Circulation: Cardiovascular Imaging; https://iris.unil.ch/handle/iris/49624; serval:BIB_56C05C3716CD; 001382908400007

Dostupnosť: https://iris.unil.ch/handle/iris/49624
https://doi.org/10.1161/CIRCIMAGING.124.016992

Inducible CXCL12/CXCR4-dependent extramedullary hematopoietic niches in the adrenal gland.

Autori: Schyrr, F. Alonso-Calleja, A. Vijaykumar, A. a ďalší

Predmety: Animals, Receptors, CXCR4/metabolism, CXCR4/genetics, Chemokine CXCL12/metabolism, Mice, Hematopoietic Stem Cells/metabolism, Hematopoietic Stem Cells/pathology, Adrenal Glands/metabolism, Adrenal Glands/pathology, Stem Cell Niche, Inbred C57BL, Humans, Receptor, Platelet-Derived Growth Factor alpha/metabolism, Platelet-Derived Growth Factor alpha/genetics, Leptin/metabolism, Leptin/genetics, Hematopoiesis, Extramedullary, Splenectomy, Transgenic

Popis súboru: application/pdf

Relation: Blood; https://iris.unil.ch/handle/iris/45710; serval:BIB_608A40306195; 001304307100001

Dostupnosť: https://iris.unil.ch/handle/iris/45710
https://doi.org/10.1182/blood.2023020875