Suchergebnisse - "CELL adhesion molecules"

Membrane trafficking of synaptic adhesion molecules.

Autoren: Bogaciu CA Rizzoli SO

Quelle: The Journal of physiology [J Physiol] 2025 Oct; Vol. 603 (20), pp. 5921-5934. Date of Electronic Publication: 2024 Sep 25.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

MeSH-Schlagworte: Synapses*/physiology , Synapses*/metabolism , Cell Adhesion Molecules*/metabolism , Cell Membrane*/metabolism, Animals ; Humans ; Protein Transport/physiology ; Endocytosis/physiology ; Cell Adhesion Molecules, Neuronal/metabolism

Bi-allelic NRXN1α deletion in microglia derived from iPSC of an autistic patient increases interleukin-6 production and impairs supporting function on neuronal networking.

Autoren: Bose R Posada-Pérez M Karvela E et al.

Quelle: Brain, behavior, and immunity [Brain Behav Immun] 2025 Jan; Vol. 123, pp. 28-42. Date of Electronic Publication: 2024 Sep 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

MeSH-Schlagworte: Microglia*/metabolism , Induced Pluripotent Stem Cells*/metabolism , Interleukin-6*/metabolism , Interleukin-6*/genetics , Neural Cell Adhesion Molecules*/metabolism , Neural Cell Adhesion Molecules*/genetics , Calcium-Binding Proteins*/metabolism , Calcium-Binding Proteins*/genetics , Neurons*/metabolism , Autism Spectrum Disorder*/genetics , Autism Spectrum Disorder*/metabolism, Humans ; Cell Adhesion Molecules, Neuronal/genetics ; Cell Adhesion Molecules, Neuronal/metabolism ; Autistic Disorder/genetics ; Autistic Disorder/metabolism ; Gene Deletion ; Nerve Net/metabolism ; Male ; Alleles

Glutamate Signaling and Neuroligin/Neurexin Adhesion Play Opposing Roles That Are Mediated by Major Histocompatibility Complex I Molecules in Cortical Synapse Formation.

Autoren: Sell GL Barrow SL McAllister AK

Quelle: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2024 Dec 04; Vol. 44 (49). Date of Electronic Publication: 2024 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Cell Adhesion Molecules, Neuronal*/metabolism , Synapses*/metabolism , Synapses*/physiology , Glutamic Acid*/metabolism , Cerebral Cortex*/metabolism , Cerebral Cortex*/cytology, Animals ; Mice ; Rats ; Male ; Female ; Receptors, N-Methyl-D-Aspartate/metabolism ; Signal Transduction/physiology ; Cells, Cultured ; Rats, Sprague-Dawley ; Neurons/metabolism ; Neurons/physiology ; Neural Cell Adhesion Molecules/metabolism ; Mice, Inbred C57BL ; Nerve Tissue Proteins/metabolism ; Neuroligins ; Calcium-Binding Proteins

Evidence of neurocognitive and resting state functional connectivity differences in carriers of NRXN1 deletions.

Autoren: Fitzgerald J Molloy CJ Dinneen T et al.

Quelle: Journal of neurodevelopmental disorders [J Neurodev Disord] 2025 Oct 15; Vol. 17 (1), pp. 62. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101483832 Publication Model: Electronic Cited Medium: Internet ISSN: 1866-1955 (Electronic) Linking ISSN: 18661947 NLM ISO Abbreviation: J Neurodev Disord Subsets: MEDLINE

MeSH-Schlagworte: Calcium-Binding Proteins*/genetics , Brain*/diagnostic imaging , Brain*/physiopathology , Neural Cell Adhesion Molecules*/genetics , Cell Adhesion Molecules, Neuronal*/genetics , Cognition*/physiology, Humans ; Female ; Male ; Magnetic Resonance Imaging ; Adult ; Young Adult ; Diffusion Tensor Imaging ; Adolescent ; Neuropsychological Tests ; Gene Deletion ; Neural Pathways/diagnostic imaging ; Neural Pathways/physiopathology ; Executive Function/physiology

POSTN Enhances the Proliferation of Goat Skin Fibroblasts Through the TGFβ Pathway Activation.

Autoren: Xu X Yan W Song M et al.

Quelle: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Dec 15; Vol. 39 (23), pp. e71269.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH-Schlagworte: Fibroblasts*/metabolism , Fibroblasts*/cytology , Cell Proliferation*/physiology , Transforming Growth Factor beta*/metabolism , Signal Transduction*/physiology , Skin*/metabolism , Skin*/cytology , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/genetics, Animals ; Goats ; Extracellular Matrix/metabolism ; Cells, Cultured ; Cell Movement

Preclinical Pharmacokinetic, Pharmacodynamic, and Safety Profile of OBI-992: A Novel TROP2-Targeted Antibody-Drug Conjugate.

Autoren: Shia CS Wen SN Hsu RY et al.

Quelle: Molecular cancer therapeutics [Mol Cancer Ther] 2025 Dec 02; Vol. 24 (12), pp. 1938-1947.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

MeSH-Schlagworte: Immunoconjugates*/pharmacology , Immunoconjugates*/pharmacokinetics , Immunoconjugates*/adverse effects , Antigens, Neoplasm*/immunology , Cell Adhesion Molecules*/antagonists & inhibitors , Cell Adhesion Molecules*/immunology, Animals ; Humans ; Mice ; Xenograft Model Antitumor Assays ; Rats ; Cell Line, Tumor ; Female ; Male ; Macaca fascicularis ; Camptothecin/analogs & derivatives ; Camptothecin/pharmacokinetics ; Camptothecin/pharmacology

Real-time FRET assay for monitoring detyrosination by TMCP1 and VASH2.

Autoren: Simon M Espeut J Juge F et al.

Quelle: Protein science : a publication of the Protein Society [Protein Sci] 2025 Dec; Vol. 34 (12), pp. e70374.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

MeSH-Schlagworte: Fluorescence Resonance Energy Transfer*/methods , Tyrosine*/analogs & derivatives , Tyrosine*/metabolism , Tyrosine*/chemistry , Tubulin*/metabolism , Tubulin*/chemistry , Carboxypeptidases*/metabolism , Carboxypeptidases*/chemistry , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/chemistry , Enzyme Assays*/methods, Humans ; Kinetics

Involvement of Periostin in Acute Neuronal Apoptosis Induced by Subarachnoid Hemorrhage in Mice and its Suppression by Clarithromycin.

Autoren: Oinaka H Kanamaru H Kawakita F et al.

Quelle: Neurocritical care [Neurocrit Care] 2025 Dec; Vol. 43 (3), pp. 876-886. Date of Electronic Publication: 2025 Sep 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 101156086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-0961 (Electronic) Linking ISSN: 15416933 NLM ISO Abbreviation: Neurocrit Care Subsets: MEDLINE

MeSH-Schlagworte: Subarachnoid Hemorrhage*/metabolism , Subarachnoid Hemorrhage*/drug therapy , Subarachnoid Hemorrhage*/complications , Subarachnoid Hemorrhage*/pathology , Apoptosis*/drug effects , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/drug effects , Clarithromycin*/pharmacology , Clarithromycin*/administration & dosage , Neurons*/drug effects , Neurons*/metabolism , Neurons*/pathology , Anti-Bacterial Agents*/pharmacology, Animals ; Male ; Mice ; Mice, Inbred C57BL ; Disease Models, Animal ; Periostin

Regulatory role of POSTN in keloid pathogenesis.

Autoren: Jiang B Zhuo F Li X et al.

Quelle: Molecular medicine reports [Mol Med Rep] 2025 Dec; Vol. 32 (6). Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-3004 (Electronic) Linking ISSN: 17912997 NLM ISO Abbreviation: Mol Med Rep Subsets: MEDLINE

MeSH-Schlagworte: Keloid*/pathology , Keloid*/metabolism , Keloid*/genetics , Cell Adhesion Molecules*/genetics , Cell Adhesion Molecules*/metabolism, Humans ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Signal Transduction ; Cell Proliferation ; Interleukin-4/metabolism ; Gene Expression Regulation ; Gene Expression Profiling ; Adult ; Male ; Interleukin-13/metabolism ; Cells, Cultured ; Female

Periostin: A matricellular protein with a multifaceted role in tumorigenesis (Review).

Autoren: Xian Y Wang L

Quelle: International journal of molecular medicine [Int J Mol Med] 2025 Dec; Vol. 56 (6). Date of Electronic Publication: 2025 Oct 24.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE

MeSH-Schlagworte: Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/genetics , Cell Adhesion Molecules*/chemistry , Neoplasms*/metabolism , Neoplasms*/pathology , Neoplasms*/genetics , Carcinogenesis*/metabolism , Carcinogenesis*/genetics , Carcinogenesis*/pathology, Humans ; Animals ; Tumor Microenvironment ; Extracellular Matrix/metabolism ; Periostin

POSTN promotes ferroptosis and contributes to the pathogenesis of IgA nephropathy via GPX4 downregulation.

Autoren: Jia W Wu Y

Quelle: Acta histochemica [Acta Histochem] 2025 Dec; Vol. 127 (4), pp. 152296. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 0370320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0372 (Electronic) Linking ISSN: 00651281 NLM ISO Abbreviation: Acta Histochem Subsets: MEDLINE

MeSH-Schlagworte: Ferroptosis* , Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism , Phospholipid Hydroperoxide Glutathione Peroxidase*/genetics , Glomerulonephritis, IGA*/metabolism , Glomerulonephritis, IGA*/pathology , Glomerulonephritis, IGA*/genetics , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/genetics, Humans ; Down-Regulation ; Mesangial Cells/metabolism ; Mesangial Cells/pathology

A critical affinity window for IgSF proteins DIP-α and Dpr10 is required for proper motor neuron arborization.

Autoren: Lopez DH Rostam KD Zamurrad S et al.

Quelle: Genes & development [Genes Dev] 2025 Dec 01; Vol. 39 (23-24), pp. 1426-1433. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Electronic Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE

MeSH-Schlagworte: Motor Neurons*/cytology , Motor Neurons*/metabolism , Motor Neurons*/physiology , Drosophila Proteins*/metabolism , Drosophila Proteins*/genetics , Drosophila melanogaster*/embryology , Drosophila melanogaster*/metabolism , Drosophila melanogaster*/genetics , Cell Adhesion Molecules*/metabolism, Animals ; Pseudopodia/metabolism ; Protein Binding ; Neuromuscular Junction

A single Drosophila Dscam1 genomic locus generates a vast repertoire of circRNAs facilitated by RNA pairing.

Autoren: Li Z Xu B Wang Z et al.

Quelle: Insect biochemistry and molecular biology [Insect Biochem Mol Biol] 2025 Dec; Vol. 185, pp. 104423. Date of Electronic Publication: 2025 Oct 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 9207282 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0240 (Electronic) Linking ISSN: 09651748 NLM ISO Abbreviation: Insect Biochem Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: RNA, Circular*/genetics , RNA, Circular*/metabolism , Drosophila Proteins*/genetics , Drosophila Proteins*/metabolism , Drosophila melanogaster*/genetics , Drosophila melanogaster*/metabolism , Cell Adhesion Molecules*/genetics , Cell Adhesion Molecules*/metabolism, Animals ; Alternative Splicing ; Exons

Research hotspots and frontier analysis of the novel immune checkpoint Nectin-4.

Autoren: Qiao Y Zhao W Gou Y et al.

Quelle: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2504776. Date of Electronic Publication: 2025 May 17.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH-Schlagworte: Cell Adhesion Molecules*/immunology , Cell Adhesion Molecules*/metabolism , Immunoconjugates*/therapeutic use , Nectins*/immunology , Immune Checkpoint Inhibitors*/therapeutic use, Humans ; Immunotherapy/methods ; Urinary Bladder Neoplasms/immunology ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/therapy ; Animals

Dual implication of endothelial adhesion molecules in tumor progression and cancer immunity.

Autoren: Chriqui LE Cavin S Perentes JY

Quelle: Cell adhesion & migration [Cell Adh Migr] 2025 Dec; Vol. 19 (1), pp. 2472308. Date of Electronic Publication: 2025 Mar 12.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101469464 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-6926 (Electronic) Linking ISSN: 19336918 NLM ISO Abbreviation: Cell Adh Migr Subsets: MEDLINE

MeSH-Schlagworte: Neoplasms*/immunology , Neoplasms*/pathology , Neoplasms*/metabolism , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/immunology, Humans ; Disease Progression ; Animals

Extracellular Domain Shedding of TROP2 Activates EGFR Signaling to Drive Prostate Cancer Metastasis.

Autoren: Liu S Hsu EC Aslan M et al.

Quelle: Cancer research [Cancer Res] 2025 Dec 01; Vol. 85 (23), pp. 4632-4647.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

MeSH-Schlagworte: Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/metabolism , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/chemistry , Cell Adhesion Molecules*/genetics , ErbB Receptors*/metabolism , Antigens, Neoplasm*/metabolism , Antigens, Neoplasm*/chemistry , Antigens, Neoplasm*/genetics, Humans ; Male ; Signal Transduction ; Animals ; Cell Movement ; Mice ; Cell Line, Tumor ; Neoplasm Metastasis ; Cell Proliferation ; Epithelial-Mesenchymal Transition

Diagnostic value of CEACAM6 and HE4 in pleural fluid for malignant pleural effusion.

Autoren: Li J Lin L Yang S et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2489748. Date of Electronic Publication: 2025 Apr 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/analysis , Pleural Effusion, Malignant*/diagnosis , Pleural Effusion, Malignant*/metabolism , Antigens, CD*/metabolism , Antigens, CD*/analysis , WAP Four-Disulfide Core Domain Protein 2* , Proteins*/metabolism , Proteins*/analysis, Humans ; Male ; Female ; GPI-Linked Proteins/metabolism ; GPI-Linked Proteins/analysis ; Middle Aged ; Aged ; Prospective Studies ; ROC Curve ; Biomarkers, Tumor/metabolism ; Adult ; Aged, 80 and over ; Area Under Curve

De novo discovery and preclinical evaluation of a novel peptide radiotracer for PET imaging of TROP-2 in non-small cell lung cancer.

Autoren: Yu X Fang J Xue Y et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109204. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Antigens, Neoplasm*/metabolism , Antigens, Neoplasm*/analysis , Positron-Emission Tomography* , Lung Neoplasms*/diagnostic imaging , Lung Neoplasms*/metabolism , Carcinoma, Non-Small-Cell Lung*/diagnostic imaging , Carcinoma, Non-Small-Cell Lung*/metabolism , Peptides*/chemistry , Peptides*/chemical synthesis , Peptides*/pharmacology , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/analysis , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/chemical synthesis , Radiopharmaceuticals*/pharmacology , Drug Discovery*, Humans ; Animals ; Mice ; Molecular Structure ; Gallium Radioisotopes/chemistry ; Structure-Activity Relationship ; Tissue Distribution ; Dose-Response Relationship, Drug ; Cell Line, Tumor

The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis.

Autoren: Chatterjee P Canale V King SJ et al.

Quelle: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2526136. Date of Electronic Publication: 2025 Jul 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH-Schlagworte: Protein Tyrosine Phosphatase, Non-Receptor Type 2*/genetics , Protein Tyrosine Phosphatase, Non-Receptor Type 2*/metabolism , Inflammatory Bowel Diseases*/genetics , Inflammatory Bowel Diseases*/microbiology , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/genetics , Antigens, CD*/metabolism , Antigens, CD*/genetics, Humans ; Genetic Predisposition to Disease ; Polymorphism, Single Nucleotide ; Animals ; Mice ; Janus Kinases/metabolism ; Janus Kinases/genetics ; Alleles ; HT29 Cells ; Signal Transduction ; Mice, Knockout ; STAT Transcription Factors/metabolism ; STAT Transcription Factors/genetics ; Intestinal Mucosa/microbiology ; Epithelial Cells/microbiology ; GPI-Linked Proteins

Rapid and specific immunoPET imaging of Nectin-4 in gastric cancer and non-small cell lung cancer using [ ⁶⁴ Cu]Cu-NOTA-EV-F(ab') 2 .

Autoren: Huang W Sun X Li X et al.

Quelle: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2025 Dec; Vol. 53 (1), pp. 619-632. Date of Electronic Publication: 2025 Jun 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE

MeSH-Schlagworte: Stomach Neoplasms*/diagnostic imaging , Stomach Neoplasms*/metabolism , Copper Radioisotopes* , Carcinoma, Non-Small-Cell Lung*/diagnostic imaging , Carcinoma, Non-Small-Cell Lung*/metabolism , Lung Neoplasms*/diagnostic imaging , Lung Neoplasms*/metabolism , Heterocyclic Compounds, 1-Ring*/chemistry , Cell Adhesion Molecules*/metabolism , Cell Adhesion Molecules*/immunology, Animals ; Humans ; Mice ; Cell Line, Tumor ; Tissue Distribution ; Radiopharmaceuticals/pharmacokinetics ; Nectins