Suchergebnisse - "CARBAPENEMS"

Global, regional, and national burden of bacterial carbapenem resistance from 1990 to 2021 and predictions up to 2035.

Autoren: Tai JH Lyu YY Zhang YS et al.

Quelle: International journal of antimicrobial agents [Int J Antimicrob Agents] 2025 Dec; Vol. 66 (6), pp. 107636. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE

MeSH-Schlagworte: Carbapenems*/pharmacology , Carbapenems*/therapeutic use , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/therapeutic use, Humans ; Global Health ; Aged ; Adult ; Middle Aged ; Child, Preschool ; Child ; Bayes Theorem ; Infant ; Adolescent ; Young Adult ; Klebsiella pneumoniae/drug effects ; Disability-Adjusted Life Years ; Male ; Infant, Newborn ; Female ; Aged, 80 and over

Drug Resistance Analysis and Prediction Model Construction of Carbapenem-Resistant Acinetobacter baumannii .

Autoren: Jin C Xu T Xie Q

Quelle: Microbial drug resistance (Larchmont, N.Y.) [Microb Drug Resist] 2025 Dec; Vol. 31 (12), pp. 385-393. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9508567 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-8448 (Electronic) Linking ISSN: 10766294 NLM ISO Abbreviation: Microb Drug Resist Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/isolation & purification , Carbapenems*/pharmacology , Anti-Bacterial Agents*/pharmacology , Acinetobacter Infections*/microbiology , Acinetobacter Infections*/drug therapy , Acinetobacter Infections*/epidemiology , Drug Resistance, Multiple, Bacterial*, Humans ; Microbial Sensitivity Tests/methods ; Male ; Female ; Middle Aged ; Aged ; Risk Factors ; Adult

Cefiderocol-containing regimens versus best available therapy for carbapenem-resistant Acinetobacter infections.

Autoren: Murphy M Shah PJ Thibeaux M

Quelle: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2025 Nov 24; Vol. 82 (Supplement_6), pp. S2995-S3002.

Publikationsart: Journal Article; Multicenter Study; Comparative Study

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 9503023 Publication Model: Print Cited Medium: Internet ISSN: 1535-2900 (Electronic) Linking ISSN: 10792082 NLM ISO Abbreviation: Am J Health Syst Pharm Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter Infections*/drug therapy , Acinetobacter Infections*/mortality , Acinetobacter Infections*/microbiology , Anti-Bacterial Agents*/administration & dosage , Anti-Bacterial Agents*/therapeutic use , Carbapenems*/pharmacology , Carbapenems*/therapeutic use , Cefiderocol*/administration & dosage , Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/isolation & purification , Cephalosporins*/administration & dosage , Cephalosporins*/therapeutic use, Humans ; Male ; Retrospective Studies ; Female ; Aged ; Middle Aged ; Cohort Studies ; Aged, 80 and over

β-lactamase inhibitors: a promising strategy for restoring carbapenem effectiveness.

Autoren: Yekani M Ghanbari H Azimi S et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Nov 15; Vol. 1007, pp. 178226. Date of Electronic Publication: 2025 Oct 07.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: beta-Lactamase Inhibitors*/pharmacology , beta-Lactamase Inhibitors*/therapeutic use , Carbapenems*/pharmacology , Carbapenems*/therapeutic use , beta-Lactamases*/metabolism , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/therapeutic use, Humans ; Animals

CRAB-RSS: development and validation of a single-center risk stratification model for carbapenem-resistant Acinetobacter baumannii in ICU patients based on mechanical ventilation, carbapenem exposure, and hospitalization duration.

Autoren: Li K Wang J Li L

Quelle: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Nov 06; Vol. 15, pp. 1659853. Date of Electronic Publication: 2025 Nov 06 (Print Publication: 2025).

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter baumannii*/drug effects , Carbapenems*/therapeutic use , Carbapenems*/pharmacology , Acinetobacter Infections*/drug therapy , Acinetobacter Infections*/microbiology , Acinetobacter Infections*/epidemiology , Respiration, Artificial* , Anti-Bacterial Agents*/therapeutic use , Anti-Bacterial Agents*/pharmacology, Humans ; Intensive Care Units ; Male ; Female ; Retrospective Studies ; Middle Aged ; Aged ; Risk Assessment/methods ; Risk Factors ; Hospitalization ; ROC Curve ; Length of Stay

Comparison of different colistin sulfate regimens for carbapenem-resistant gram-negative bacteria pneumonia in neurocritical care patients: a retrospective cohort study.

Autoren: Zeng Q Huang H Lu J et al.

Quelle: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Nov 05; Vol. 69 (11), pp. e0064425. Date of Electronic Publication: 2025 Sep 22.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

MeSH-Schlagworte: Colistin*/therapeutic use , Anti-Bacterial Agents*/therapeutic use , Carbapenems*/therapeutic use , Carbapenems*/pharmacology , Gram-Negative Bacteria*/drug effects , Gram-Negative Bacteria*/pathogenicity , Pneumonia, Bacterial*/drug therapy , Pneumonia, Bacterial*/microbiology , Gram-Negative Bacterial Infections*/drug therapy , Gram-Negative Bacterial Infections*/microbiology, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Aged ; Intensive Care Units ; Critical Care ; Cross Infection/drug therapy ; Cross Infection/microbiology

Clinical characteristics and treatment outcomes of Acinetobacter baumannii bloodstream infections in a setting with high carbapenem susceptibility among isolates.

Autoren: Ngiam JN Koh MCY Chew KL

Quelle: Microbiology spectrum [Microbiol Spectr] 2025 Nov 04; Vol. 13 (11), pp. e0160725. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/isolation & purification , Carbapenems*/pharmacology , Carbapenems*/therapeutic use , Acinetobacter Infections*/drug therapy , Acinetobacter Infections*/microbiology , Acinetobacter Infections*/mortality , Anti-Bacterial Agents*/therapeutic use , Anti-Bacterial Agents*/pharmacology , Bacteremia*/drug therapy , Bacteremia*/microbiology , Bacteremia*/mortality, Humans ; Male ; Female ; Middle Aged ; Aged ; Treatment Outcome ; Microbial Sensitivity Tests ; Aged, 80 and over ; Retrospective Studies ; Adult ; Hospital Mortality

Comparative epidemiology and resistance mechanisms of carbapenem-, tigecycline-, and polymyxin-resistant Enterobacteriaceae in pediatric diarrhea: A cross-sectional study in 2017 and 2023.

Autoren: Zhang J Wang H Ni Y et al.

Quelle: International journal of antimicrobial agents [Int J Antimicrob Agents] 2025 Nov; Vol. 66 (5), pp. 107580. Date of Electronic Publication: 2025 Jul 23.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 9111860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7913 (Electronic) Linking ISSN: 09248579 NLM ISO Abbreviation: Int J Antimicrob Agents Subsets: MEDLINE

MeSH-Schlagworte: Diarrhea*/microbiology , Diarrhea*/epidemiology , Diarrhea*/drug therapy , Anti-Bacterial Agents*/pharmacology , Tigecycline*/pharmacology , Enterobacteriaceae Infections*/epidemiology , Enterobacteriaceae Infections*/microbiology , Enterobacteriaceae Infections*/drug therapy , Carbapenems*/pharmacology , Enterobacteriaceae*/drug effects , Enterobacteriaceae*/genetics , Enterobacteriaceae*/isolation & purification , Polymyxins*/pharmacology , Drug Resistance, Multiple, Bacterial*/genetics, Humans ; Cross-Sectional Studies ; Microbial Sensitivity Tests ; Child, Preschool ; Infant ; Plasmids/genetics ; Female ; Male ; China/epidemiology ; Child ; Feces/microbiology ; Whole Genome Sequencing ; Bacterial Proteins/genetics ; Carbapenem-Resistant Enterobacteriaceae/genetics ; Carbapenem-Resistant Enterobacteriaceae/drug effects ; beta-Lactamases/genetics

Minocycline-based therapy for carbapenem-resistant Acinetobacter baumannii pneumonia: A multicenter retrospective study.

Autoren: Seok H Kim SH Shi HJ et al.

Quelle: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2025 Nov; Vol. 160, pp. 108064. Date of Electronic Publication: 2025 Sep 12.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Canada NLM ID: 9610933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3511 (Electronic) Linking ISSN: 12019712 NLM ISO Abbreviation: Int J Infect Dis Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter baumannii*/drug effects , Anti-Bacterial Agents*/therapeutic use , Acinetobacter Infections*/drug therapy , Acinetobacter Infections*/microbiology , Acinetobacter Infections*/mortality , Carbapenems*/pharmacology , Carbapenems*/therapeutic use , Minocycline*/therapeutic use , Pneumonia, Bacterial*/drug therapy , Pneumonia, Bacterial*/microbiology, Humans ; Retrospective Studies ; Male ; Female ; Aged ; Middle Aged ; Republic of Korea ; Treatment Outcome ; Aged, 80 and over ; Drug Resistance, Multiple, Bacterial ; Adult

The impact of carbapenem-resistant infections in intensive care units: focus on non-fermenting gram-negative bacilli and survival analysis.

Autoren: Dessemon J Vacheron CH Savey A et al.

Körperschaften: Dessemon J Vacheron CH Savey A et al.

Quelle: Antimicrobial resistance and infection control [Antimicrob Resist Infect Control] 2025 Oct 21; Vol. 14 (1), pp. 127. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101585411 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-2994 (Electronic) Linking ISSN: 20472994 NLM ISO Abbreviation: Antimicrob Resist Infect Control Subsets: MEDLINE

MeSH-Schlagworte: Intensive Care Units*/statistics & numerical data , Carbapenems*/pharmacology , Gram-Negative Bacterial Infections*/mortality , Gram-Negative Bacterial Infections*/microbiology , Gram-Negative Bacterial Infections*/drug therapy , Gram-Negative Bacterial Infections*/epidemiology , Gram-Negative Bacteria*/drug effects , Cross Infection*/microbiology , Cross Infection*/mortality , Cross Infection*/epidemiology , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Aged ; France/epidemiology ; Survival Analysis ; Adult

Genomic analysis of carbapenem resistant Acinetobacter baumannii outbreak in a burn intensive care unit of a tertiary-care hospital in Madrid, Spain.

Autoren: Maldonado-Barrueco A Rubio-Mora E Bloise I et al.

Quelle: Antimicrobial resistance and infection control [Antimicrob Resist Infect Control] 2025 Oct 21; Vol. 14 (1), pp. 124. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101585411 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-2994 (Electronic) Linking ISSN: 20472994 NLM ISO Abbreviation: Antimicrob Resist Infect Control Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter baumannii*/genetics , Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/isolation & purification , Carbapenems*/pharmacology , Disease Outbreaks* , Acinetobacter Infections*/epidemiology , Acinetobacter Infections*/microbiology , Cross Infection*/epidemiology , Cross Infection*/microbiology, Humans ; Spain/epidemiology ; Tertiary Care Centers ; Male ; Middle Aged ; Aged ; Adult ; Microbial Sensitivity Tests ; Female ; Whole Genome Sequencing ; Anti-Bacterial Agents/pharmacology ; Burn Units ; Drug Resistance, Multiple, Bacterial/genetics ; Genome, Bacterial ; beta-Lactamases/genetics ; Intensive Care Units ; Bacterial Proteins/genetics ; Genomics

Prevalence of on time administration of carbapenem and its impact on PK/PD target attainment in hospitalized patients: a multicenter retrospective study.

Autoren: Song J Pang X Chen H et al.

Quelle: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Oct 17; Vol. 15, pp. 1690269. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/administration & dosage , Anti-Bacterial Agents*/pharmacokinetics , Carbapenems*/pharmacokinetics , Carbapenems*/administration & dosage, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Hospitalization ; Imipenem/pharmacokinetics ; Imipenem/administration & dosage ; Meropenem/pharmacokinetics ; Meropenem/administration & dosage ; Microbial Sensitivity Tests ; Prevalence ; Retrospective Studies ; Time Factors

Sulbactam-durlobactam improves cephalosporin and carbapenem susceptibility and time-kill effect against Mycobacterium abscessus .

Autoren: Shrivastava A Boorgula GD Singh S et al.

Quelle: Microbiology spectrum [Microbiol Spectr] 2025 Oct 07; Vol. 13 (10), pp. e0149225. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/pharmacology , Mycobacterium abscessus*/drug effects , Cephalosporins*/pharmacology , Carbapenems*/pharmacology , Sulbactam*/pharmacology , Azabicyclo Compounds*/pharmacology , beta-Lactamase Inhibitors*/pharmacology, Microbial Sensitivity Tests ; Humans ; Mycobacterium Infections, Nontuberculous/microbiology ; Mycobacterium Infections, Nontuberculous/drug therapy ; Drug Synergism

Comparative outcomes of polymyxins in neurocritical care patients with carbapenem-resistant Gram-negative bacterial pneumonia: a retrospective cohort study.

Autoren: Zeng Q Huang H Lu J et al.

Quelle: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2025 Oct 03; Vol. 80 (10), pp. 2759-2772.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/therapeutic use , Anti-Bacterial Agents*/adverse effects , Carbapenems*/pharmacology , Carbapenems*/therapeutic use , Polymyxins*/therapeutic use , Polymyxins*/adverse effects , Pneumonia, Bacterial*/drug therapy , Pneumonia, Bacterial*/microbiology , Pneumonia, Bacterial*/mortality , Gram-Negative Bacterial Infections*/drug therapy , Gram-Negative Bacterial Infections*/microbiology , Gram-Negative Bacteria*/drug effects, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Aged ; Colistin/therapeutic use ; Colistin/analogs & derivatives ; Colistin/adverse effects ; Treatment Outcome ; Critical Care ; Polymyxin B/therapeutic use ; Polymyxin B/adverse effects ; Aged, 80 and over ; Adult

Effectiveness comparison between ceftazidime-avibactam and carbapenem-based regimens in nosocomial carbapenem-resistant Klebsiella pneumoniae bloodstream infections.

Autoren: Huang RC Chen LY Wang YC et al.

Quelle: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2025 Oct; Vol. 58 (5), pp. 579-584. Date of Electronic Publication: 2025 Mar 04.

Publikationsart: Equivalence Trial; Journal Article; Observational Study

Info zur Zeitschrift: Publisher: published by Elsevier for the Taiwan Society of Microbiology Country of Publication: England NLM ID: 100956211 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1995-9133 (Electronic) Linking ISSN: 16841182 NLM ISO Abbreviation: J Microbiol Immunol Infect Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/therapeutic use , Azabicyclo Compounds*/therapeutic use , Bacteremia*/drug therapy , Bacteremia*/microbiology , Bacteremia*/mortality , Carbapenem-Resistant Enterobacteriaceae*/drug effects , Carbapenems*/therapeutic use , Carbapenems*/pharmacology , Ceftazidime*/therapeutic use , Cross Infection*/drug therapy , Cross Infection*/microbiology , Cross Infection*/mortality , Klebsiella Infections*/drug therapy , Klebsiella Infections*/mortality , Klebsiella Infections*/microbiology , Klebsiella pneumoniae*/drug effects, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Drug Combinations ; Retrospective Studies ; Treatment Outcome

Dual mechanism of the OXA-23 carbapenemase inhibition by the carbapenem NA-1-157.

Autoren: Toth M Stewart NK Quan P et al.

Quelle: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Oct; Vol. 69 (10), pp. e0091825. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

MeSH-Schlagworte: beta-Lactamases*/metabolism , Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/enzymology , Anti-Bacterial Agents*/pharmacology , Carbapenems*/pharmacology , Carbapenems*/chemistry , Bacterial Proteins*/antagonists & inhibitors , Bacterial Proteins*/metabolism , beta-Lactamase Inhibitors*/pharmacology, Microbial Sensitivity Tests ; Meropenem/pharmacology ; Molecular Dynamics Simulation ; Imipenem/pharmacology ; Kinetics ; Humans

Demystify Carbapenem-resistant Acinetobacter baumannii Pneumonia Burden: 2-Year Cohort Study.

Autoren: Rosyid AN Endraswari PD Setiawan F et al.

Quelle: Annals of African medicine [Ann Afr Med] 2025 Oct 01; Vol. 24 (4), pp. 909-915. Date of Electronic Publication: 2025 Aug 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Medknow Publications Country of Publication: India NLM ID: 101231417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0975-5764 (Electronic) Linking ISSN: 09755764 NLM ISO Abbreviation: Ann Afr Med Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/isolation & purification , Acinetobacter Infections*/drug therapy , Acinetobacter Infections*/epidemiology , Acinetobacter Infections*/microbiology , Acinetobacter Infections*/mortality , Acinetobacter Infections*/economics , Carbapenems*/pharmacology , Carbapenems*/therapeutic use , Anti-Bacterial Agents*/therapeutic use , Anti-Bacterial Agents*/pharmacology , Pneumonia, Bacterial*/drug therapy , Pneumonia, Bacterial*/microbiology , Pneumonia, Bacterial*/epidemiology , Pneumonia, Bacterial*/mortality , Pneumonia, Bacterial*/economics, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Community-Acquired Infections/drug therapy ; Community-Acquired Infections/microbiology ; Community-Acquired Infections/epidemiology ; Community-Acquired Infections/economics ; Length of Stay ; Adult ; Microbial Sensitivity Tests ; Drug Resistance, Bacterial ; Cohort Studies

Synthesis and antibacterial evaluation of 5-(3-nitrophenyl)-N'-arylisoxazole-3-carbohydrazide derivatives against carbapenem-resistant Acinetobacterbaumannii.

Autoren: Bandela R Tupare RR Saxena D et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118154. Date of Electronic Publication: 2025 Sep 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Anti-Bacterial Agents*/chemistry , Acinetobacter baumannii*/drug effects , Carbapenems*/pharmacology , Hydrazines*/pharmacology , Hydrazines*/chemistry , Hydrazines*/chemical synthesis , Isoxazoles*/pharmacology , Isoxazoles*/chemistry , Isoxazoles*/chemical synthesis, Microbial Sensitivity Tests ; Structure-Activity Relationship ; Molecular Structure ; Animals ; Dose-Response Relationship, Drug ; Chlorocebus aethiops ; Vero Cells ; Drug Resistance, Bacterial/drug effects

Structural and dynamic roles of tandem acyl carrier proteins in aryl polyene biosynthesis in carbapenem-resistant Acinetobacter baumannii.

Autoren: Lee CY Son M Lee WC et al.

Quelle: Protein science : a publication of the Protein Society [Protein Sci] 2025 Dec; Vol. 34 (12), pp. e70382.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

MeSH-Schlagworte: Acinetobacter baumannii*/metabolism , Acinetobacter baumannii*/genetics , Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/chemistry , Acyl Carrier Protein*/chemistry , Acyl Carrier Protein*/metabolism , Acyl Carrier Protein*/genetics , Carbapenems*/pharmacology , Bacterial Proteins*/metabolism , Bacterial Proteins*/chemistry , Bacterial Proteins*/genetics , Polyenes*/metabolism , Polyenes*/chemistry, Molecular Dynamics Simulation ; Anti-Bacterial Agents/pharmacology

Antimicrobial efficacy of cinnamaldehyde combined with polymyxin B against carbapenem- polymyxin-resistant Klebsiella pneumoniae.

Autoren: Vaz MSM de Almeida de Souza GH Radai JADS et al.

Quelle: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2025 Dec; Vol. 56 (4), pp. 2303-2311. Date of Electronic Publication: 2025 Aug 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Publishing Country of Publication: Brazil NLM ID: 101095924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1678-4405 (Electronic) Linking ISSN: 15178382 NLM ISO Abbreviation: Braz J Microbiol Subsets: MEDLINE

MeSH-Schlagworte: Polymyxin B*/pharmacology , Acrolein*/analogs & derivatives , Acrolein*/pharmacology , Anti-Bacterial Agents*/pharmacology , Klebsiella pneumoniae*/drug effects , Carbapenems*/pharmacology , Klebsiella Infections*/drug therapy , Klebsiella Infections*/microbiology, Microbial Sensitivity Tests ; Drug Synergism ; Animals ; Drug Resistance, Multiple, Bacterial/drug effects ; Mice