Výsledky vyhľadávania - "Butyrylcholinesterase"

The Selectivity of Butyrylcholinesterase Inhibitors Revisited.

Autori: Gambardella MD Wang Y Pang J

Zdroj: Molecules (Basel, Switzerland) [Molecules] 2025 Oct 27; Vol. 30 (21). Date of Electronic Publication: 2025 Oct 27.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/chemistry , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/therapeutic use , Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism , Alzheimer Disease*/enzymology, Humans ; Acetylcholinesterase/metabolism ; Acetylcholinesterase/chemistry ; Animals ; Amyloid beta-Peptides/metabolism

N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors.

Autori: Košak U Knez D Pišlar A a ďalší

Zdroj: Chemico-biological interactions [Chem Biol Interact] 2025 Oct 22; Vol. 420, pp. 111681. Date of Electronic Publication: 2025 Jul 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/chemistry , Pyrrolidines*/chemistry , Pyrrolidines*/pharmacology , Pyrrolidines*/metabolism , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/metabolism , Cholinesterase Inhibitors*/chemical synthesis , Monoamine Oxidase Inhibitors*/chemistry , Monoamine Oxidase Inhibitors*/pharmacology , Monoamine Oxidase Inhibitors*/metabolism , Monoamine Oxidase*/metabolism , Monoamine Oxidase*/chemistry, Humans ; Animals ; Crystallography, X-Ray ; Molecular Docking Simulation ; Amyloid beta-Peptides/toxicity ; Structure-Activity Relationship ; Peptide Fragments/toxicity

Species differences in cholinesterase expression and their translational impact.

Autori: Hodbod T Shafieikazerooni P Nemet L a ďalší

Zdroj: Chemico-biological interactions [Chem Biol Interact] 2025 Oct 22; Vol. 420, pp. 111705. Date of Electronic Publication: 2025 Aug 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/genetics , Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/genetics , Acetylcholinesterase*/metabolism, Animals ; Humans ; Species Specificity ; Mice ; Rats ; RNA, Messenger/metabolism ; RNA, Messenger/genetics ; Brain/metabolism ; Brain/enzymology ; Liver/metabolism ; Liver/enzymology ; Male ; Organ Specificity

Chiral switch of a butyrylcholinesterase inhibitor for the treatment of Alzheimer's disease.

Autori: Košak U Knez D Benetik SF a ďalší

Zdroj: Chemico-biological interactions [Chem Biol Interact] 2025 Oct 22; Vol. 420, pp. 111670. Date of Electronic Publication: 2025 Jul 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alzheimer Disease*/drug therapy , Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/chemistry , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/therapeutic use , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/metabolism , Sulfonamides*/chemistry , Sulfonamides*/therapeutic use , Sulfonamides*/pharmacology, Animals ; Humans ; Stereoisomerism ; Mice ; Acetylcholinesterase/metabolism ; Acetylcholinesterase/chemistry ; Male ; Crystallography, X-Ray

Discovery of a new function of human butyrylcholinesterase and the catalytic activity of its natural variants toward homocysteine thiolactone hydrolysis.

Autori: Chen X Li X Liu H a ďalší

Zdroj: Chemico-biological interactions [Chem Biol Interact] 2025 Oct 22; Vol. 420, pp. 111683. Date of Electronic Publication: 2025 Jul 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/genetics , Butyrylcholinesterase*/chemistry , Homocysteine*/analogs & derivatives , Homocysteine*/metabolism , Homocysteine*/chemistry, Humans ; Hydrolysis ; Polymorphism, Single Nucleotide ; Molecular Dynamics Simulation ; Acetylcholinesterase/metabolism ; Acetylcholinesterase/chemistry ; Biocatalysis ; Aryldialkylphosphatase/metabolism

The product of Ellman's reaction inhibits cholinesterases.

Autori: Stojan J Brazzolotto X

Zdroj: Protein science : a publication of the Protein Society [Protein Sci] 2025 Dec; Vol. 34 (12), pp. e70371.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/chemistry , Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/chemistry , Acetylcholinesterase*/metabolism , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/pharmacology , Thiocholine*/chemistry , Thiocholine*/metabolism, Humans ; Animals ; Mice ; Kinetics ; Electrophorus ; Catalytic Domain ; Crystallography, X-Ray ; Models, Molecular ; Torpedo

Chiral Anthranilic Amides as Potential Cholinesterase Inhibitors: Synthesis, Bioactivity Assessment, and Molecular Modeling.

Autori: Tunç T Kılınç N Demirel N a ďalší

Zdroj: Chemistry & biodiversity [Chem Biodivers] 2025 Nov; Vol. 22 (11), pp. e00974. Date of Electronic Publication: 2025 Jul 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholinesterase Inhibitors*/chemical synthesis , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Amides*/chemistry , Amides*/pharmacology , Amides*/chemical synthesis , Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/metabolism , ortho-Aminobenzoates*/chemistry , ortho-Aminobenzoates*/pharmacology , ortho-Aminobenzoates*/chemical synthesis, Structure-Activity Relationship ; Stereoisomerism ; Humans ; Molecular Structure ; Models, Molecular ; Molecular Docking Simulation ; Dose-Response Relationship, Drug

Molecular and structural characterization of ureido-benzenesulfonamides as dual inhibitors of aldose reductase and cholinesterases.

Autori: Türkeş C Lolak N Duran HE a ďalší

Zdroj: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2025 Nov; Vol. 773, pp. 110594. Date of Electronic Publication: 2025 Aug 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aldehyde Reductase*/antagonists & inhibitors , Aldehyde Reductase*/chemistry , Aldehyde Reductase*/metabolism , Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Butyrylcholinesterase*/chemistry , Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/chemistry , Acetylcholinesterase*/metabolism, Molecular Docking Simulation ; Humans ; Structure-Activity Relationship ; Animals

Low toxicity ferrocene-1,2,3-Triazole hybrids as acetylcholinesterase and butyrylcholinesterase inhibitors: Synthesis, antioxidant activity, enzyme inhibition, cytotoxicity properties and molecular docking studies.

Autori: Korkmaz R Dilitatlı S Celik M a ďalší

Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2025 Nov; Vol. 330 (Pt 1), pp. 148021. Date of Electronic Publication: 2025 Sep 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/chemical synthesis , Butyrylcholinesterase*/chemistry , Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/chemistry , Acetylcholinesterase*/metabolism , Molecular Docking Simulation* , Triazoles*/chemistry , Triazoles*/pharmacology , Triazoles*/chemical synthesis , Antioxidants*/pharmacology , Antioxidants*/chemistry , Antioxidants*/chemical synthesis , Metallocenes*/chemistry , Metallocenes*/pharmacology , Ferrous Compounds*/chemistry , Ferrous Compounds*/pharmacology , Ferrous Compounds*/chemical synthesis, Humans ; Structure-Activity Relationship ; Cell Line, Tumor

A cocaine hydrolase engineered from human butyrylcholinesterase as a medical countermeasure for aldicarb poisoning.

Autori: LeSaint JE Chandar NB Kyomuhangi A a ďalší

Zdroj: Chemico-biological interactions [Chem Biol Interact] 2025 Oct 22; Vol. 420, pp. 111675. Date of Electronic Publication: 2025 Jul 31.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/chemistry , Butyrylcholinesterase*/genetics , Aldicarb*/poisoning , Aldicarb*/toxicity , Aldicarb*/metabolism, Humans ; Animals ; Mice ; Hydrolysis ; Protein Engineering ; Medical Countermeasures ; Acetylcholinesterase/metabolism ; Acetylcholinesterase/chemistry ; Molecular Docking Simulation ; Kinetics

Structural, nonlinear optical, and molecular docking studies of schiff base compounds as multi-target inhibitors of AChE, BChE, and carbonic anhydrases.

Autori: Kourat O Benhalima N Al-Dies AM a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Oct 06; Vol. 15 (1), pp. 34818. Date of Electronic Publication: 2025 Oct 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Carbonic Anhydrase Inhibitors*/chemistry , Carbonic Anhydrase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/pharmacology , Acetylcholinesterase*/chemistry , Acetylcholinesterase*/metabolism , Butyrylcholinesterase*/chemistry , Butyrylcholinesterase*/metabolism , Carbonic Anhydrases*/metabolism , Carbonic Anhydrases*/chemistry, Schiff Bases/chemistry ; Schiff Bases/pharmacology ; Molecular Docking Simulation ; Humans ; Density Functional Theory ; Structure-Activity Relationship

Transforming ureas into carbamates: From allosteric p38α MAPK ligands to dual BChE/p38α MAPK inhibitors.

Autori: Benetik SF Meden A Knez D a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108998. Date of Electronic Publication: 2025 Sep 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Urea*/chemistry , Urea*/pharmacology , Urea*/analogs & derivatives , Carbamates*/chemistry , Carbamates*/pharmacology , Carbamates*/chemical synthesis , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/chemical synthesis , Mitogen-Activated Protein Kinase 14*/antagonists & inhibitors , Mitogen-Activated Protein Kinase 14*/metabolism , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis, Animals ; Structure-Activity Relationship ; Humans ; Ligands ; Molecular Structure ; Dose-Response Relationship, Drug ; Allosteric Regulation/drug effects ; Alzheimer Disease/drug therapy ; Mice

Exploring the potential of new acetylated unsaturated Oxindole derivatives as multi-target inhibitors for BACE1 and BuChE.

Autori: Montargil CA Pinto M Resende R a ďalší

Zdroj: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2025 Dec 15; Vol. 131, pp. 118419. Date of Electronic Publication: 2025 Sep 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aspartic Acid Endopeptidases*/antagonists & inhibitors , Aspartic Acid Endopeptidases*/metabolism , Amyloid Precursor Protein Secretases*/antagonists & inhibitors , Amyloid Precursor Protein Secretases*/metabolism , Oxindoles*/chemistry , Oxindoles*/pharmacology , Oxindoles*/chemical synthesis , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/chemical synthesis , Butyrylcholinesterase*/metabolism , Indoles*/chemistry , Indoles*/pharmacology , Indoles*/chemical synthesis, Humans ; Structure-Activity Relationship ; Molecular Docking Simulation ; Molecular Structure ; Animals ; Dose-Response Relationship, Drug ; Cell Line, Tumor ; Mice

Discovery of a highly selective BChE inhibitor with concomitant anti-neuroinflammatory activity for treating Alzheimer's disease.

Autori: Zhao Y Wu K Luo W a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118071. Date of Electronic Publication: 2025 Aug 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Cholinesterase Inhibitors*/chemical synthesis , Butyrylcholinesterase*/metabolism , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/chemistry , Neuroprotective Agents*/chemical synthesis , Drug Discovery* , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology , Anti-Inflammatory Agents, Non-Steroidal*/chemistry , Anti-Inflammatory Agents, Non-Steroidal*/chemical synthesis, Animals ; Mice ; Structure-Activity Relationship ; Humans ; Molecular Structure ; Amyloid beta-Peptides/antagonists & inhibitors ; Amyloid beta-Peptides/metabolism ; Dose-Response Relationship, Drug ; Male ; Peptide Fragments/antagonists & inhibitors

Investigation of 2-substituted-5-methylsulfonylbenzoxazole derivatives as potential cholinesterase inhibitors: Synthesis, in vitro, and computational studies.

Autori: Cihan C Faydali N Erol M a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109281. Date of Electronic Publication: 2025 Nov 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholinesterase Inhibitors*/chemical synthesis , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Acetylcholinesterase*/metabolism , Butyrylcholinesterase*/metabolism , Benzoxazoles*/chemistry , Benzoxazoles*/chemical synthesis , Benzoxazoles*/pharmacology, Molecular Docking Simulation ; Structure-Activity Relationship ; Molecular Structure ; Humans ; Dose-Response Relationship, Drug ; Animals

Dual targeting of neuroblastoma and cholinesterase by morpholino/pyrrolidino-sulfonyl-indole thiosemicarbazones: Synthesis, characterization, enzyme inhibition, cytotoxicity, docking and dynamics studies.

Autori: Batool Z Toraman GÖA Çakır F a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109252. Date of Electronic Publication: 2025 Nov 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemical synthesis , Cholinesterase Inhibitors*/chemistry , Acetylcholinesterase*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Butyrylcholinesterase*/metabolism , Thiosemicarbazones*/chemistry , Thiosemicarbazones*/pharmacology , Thiosemicarbazones*/chemical synthesis , Neuroblastoma*/drug therapy , Neuroblastoma*/metabolism , Neuroblastoma*/pathology, Humans ; Molecular Docking Simulation ; Structure-Activity Relationship ; Molecular Structure ; Drug Screening Assays, Antitumor ; Dose-Response Relationship, Drug ; Indoles/chemistry ; Indoles/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Molecular Dynamics Simulation

Synthesis of novel benzene bissulfonamides with carbonic anhydrase and choline esterase inhibitory properties.

Autori: Canoğlu U Akıncıoğlu A Öztaşkın N a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108938. Date of Electronic Publication: 2025 Aug 31.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Carbonic Anhydrase Inhibitors*/chemical synthesis , Carbonic Anhydrase Inhibitors*/pharmacology , Carbonic Anhydrase Inhibitors*/chemistry , Cholinesterase Inhibitors*/chemical synthesis , Cholinesterase Inhibitors*/pharmacology , Cholinesterase Inhibitors*/chemistry , Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/metabolism , Sulfonamides*/chemical synthesis , Sulfonamides*/pharmacology , Sulfonamides*/chemistry , Carbonic Anhydrase I*/metabolism , Carbonic Anhydrase I*/antagonists & inhibitors, Humans ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Carbonic Anhydrase II/antagonists & inhibitors ; Carbonic Anhydrase II/metabolism ; Molecular Docking Simulation

Fast-response NIR "off-on" fluorescent sensor for hepaticinjury visualization through butyrylcholinesterase expression monitoring.

Autori: Liu Q Liu M Hu S a ďalší

Zdroj: Analytica chimica acta [Anal Chim Acta] 2025 Sep 15; Vol. 1367, pp. 344332. Date of Electronic Publication: 2025 Jun 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4324 (Electronic) Linking ISSN: 00032670 NLM ISO Abbreviation: Anal Chim Acta Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/analysis , Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Chemical and Drug Induced Liver Injury*/diagnostic imaging, Animals ; Humans ; Mice ; Optical Imaging ; Indocyanine Green/chemistry ; Indocyanine Green/analogs & derivatives ; Indocyanine Green/chemical synthesis ; Liver ; Hep G2 Cells

Direct determination of kinetic parameters for the hydrolysis of a poor substrate by human plasma.

Autori: Stojan J; Institute of biochemistry and molecular genetics, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia. Electronic address: stojan@mf.uni-lj.si.

Zdroj: Chemico-biological interactions [Chem Biol Interact] 2025 Sep 05; Vol. 418, pp. 111600. Date of Electronic Publication: 2025 Jun 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/blood, Humans ; Hydrolysis ; Kinetics ; Colorimetry ; Hydrogen-Ion Concentration ; Substrate Specificity ; Butyrylthiocholine/metabolism

The role of unsaturated fatty acids in modulating human butyrylcholinesterase activity: insights from kinetics and molecular docking.

Autori: Gok M Cicek C Sari S a ďalší

Zdroj: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Sep; Vol. 398 (9), pp. 12253-12265. Date of Electronic Publication: 2025 Mar 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Butyrylcholinesterase*/metabolism , Butyrylcholinesterase*/chemistry , Cholinesterase Inhibitors*/pharmacology , Fatty Acids, Unsaturated*/pharmacology , Fatty Acids, Unsaturated*/metabolism , Fatty Acids, Unsaturated*/chemistry, Humans ; Molecular Docking Simulation ; Kinetics ; alpha-Linolenic Acid/pharmacology ; Arachidonic Acid/pharmacology ; Linoleic Acid/pharmacology