Výsledky vyhľadávania - "Brain Ischemia/metabolism [MeSH]"

Adequate post-ischemic reperfusion of the mouse brain requires endothelial NFAT5

Autori: Reiner Kunze Paul Wacker Paula Breuer a ďalší

Zdroj: Acta Neuropathol Commun
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)

Predmety: Mice, Knockout, Male, 0301 basic medicine, 0303 health sciences, Ischemic stroke, Endothelial cells, Research, Endothelial Cells, Brain, Infarction, Middle Cerebral Artery, Endothelial Cells/pathology [MeSH], Endothelial Cells/metabolism [MeSH], Brain/pathology [MeSH], Mice, Inbred C57BL [MeSH], Transcription Factors/genetics [MeSH], Brain Ischemia/metabolism [MeSH], Reperfusion Injury/metabolism [MeSH], Animals [MeSH], Mice, Knockout [MeSH], Mice [MeSH], NFAT5, Infarction, Middle Cerebral Artery/metabolism [MeSH], Male [MeSH], Brain/metabolism [MeSH], Infarction, Middle Cerebral Artery/pathology [MeSH], KCNJ2, Reperfusion Injury/pathology [MeSH], Reperfusion, Transcription Factors/metabolism [MeSH], Brain Ischemia/pathology [MeSH], Brain Ischemia, Mice, Inbred C57BL, Mice, 03 medical and health sciences, Reperfusion Injury, Animals, Neurology. Diseases of the nervous system, RC346-429, Transcription Factors

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39710754
https://doaj.org/article/239373552e3647268a841f7994bfcaf1
https://repository.publisso.de/resource/frl:6496606

(H)IF applicable: promotion of neurogenesis by induced HIF-2 signalling after ischaemia

Autori: Tristan Leu Joachim Fandrey Timm Schreiber

Zdroj: Pflugers Arch

Predmety: Male, Mice, Knockout, 0301 basic medicine, 0303 health sciences, Primary Cell Culture, Medizin, Neuroprotection, 6. Clean water, Brain Ischemia, Nerve Regeneration, Mice, Inbred C57BL, Mice, 03 medical and health sciences, Molecular and Cellular Mechanisms of Disease, Female [MeSH], Brain, Mice, Inbred C57BL [MeSH], Brain Ischemia/metabolism [MeSH], HIF-2, Animals [MeSH], Mice, Knockout [MeSH], Male [MeSH], Neuroprotection [MeSH], Molecular and cellular mechanisms of disease, Regeneration, Neurogenesis, Transcription Factors/metabolism [MeSH], Ischaemia, Primary Cell Culture [MeSH], Hypoxia/metabolism [MeSH], Nerve Regeneration [MeSH], Animals, Female, Hypoxia, Transcription Factors

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00424-021-02600-8.pdf
https://pubmed.ncbi.nlm.nih.gov/34251509
https://pubmed.ncbi.nlm.nih.gov/34251509/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302505
https://link.springer.com/content/pdf/10.1007/s00424-021-02600-8.pdf
https://link.springer.com/article/10.1007/s00424-021-02600-8
https://repository.publisso.de/resource/frl:6446942

Neuroprotective and antioxidative effects of pioglitazone in brain tissue adjacent to the ischemic core are mediated by PI3K/Akt and Nrf2/ARE pathways

Autori: Yi Zhao Ulf Lützen Peter Gohlke a ďalší

Zdroj: J Mol Med (Berl)

Predmety: Male, 0301 basic medicine, NF-E2-Related Factor 2, Gene Expression, Apoptosis, PC12 Cells, Antioxidants, Brain Ischemia, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Animals, Phosphorylation, 0303 health sciences, Pioglitazone, Nrf2, PC12 Cells [MeSH], Phosphorylation [MeSH], Brain Ischemia/etiology [MeSH], Brain Ischemia/metabolism [MeSH], Gene Expression [MeSH], NF-E2-Related Factor 2/metabolism [MeSH], Pioglitazone/pharmacology [MeSH], Original Article, Male [MeSH], Neuroprotection/drug effects [MeSH], Signal Transduction/drug effects [MeSH], Cerebrovascular Circulation/drug effects [MeSH], Disease Models, Animal [MeSH], PPARγ, Antioxidants/pharmacology [MeSH], Apoptosis/drug effects [MeSH], Rats [MeSH], Animals [MeSH], Disease Susceptibility [MeSH], PI3K/Akt, Cerebral ischemia, Neuroprotective Agents/pharmacology [MeSH], Proto-Oncogene Proteins c-akt/metabolism [MeSH], Brain Ischemia/drug therapy [MeSH], Phosphatidylinositol 3-Kinases/metabolism [MeSH], Neuroprotection, Biomarkers [MeSH], Brain Ischemia/pathology [MeSH], Rats, 3. Good health, Disease Models, Animal, Neuroprotective Agents, Cerebrovascular Circulation, Disease Susceptibility, Proto-Oncogene Proteins c-akt, Biomarkers, Signal Transduction

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00109-021-02065-3.pdf
https://pubmed.ncbi.nlm.nih.gov/33864097
https://link.springer.com/article/10.1007/s00109-021-02065-3?error=cookies_not_supported&code=df51ed68-01cc-48fe-abf0-781c5e9257f2
https://link.springer.com/article/10.1007/s00109-021-02065-3
https://link.springer.com/content/pdf/10.1007/s00109-021-02065-3.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313471/
https://pubmed.ncbi.nlm.nih.gov/33864097/
https://repository.publisso.de/resource/frl:6448303

Hypocaloric Diet Initiated Post-Ischemia Provides Long-Term Neuroprotection and Promotes Peri-Infarct Brain Remodeling by Regulating Metabolic and Survival-Promoting Proteins

Autori: Tayana Silva de Carvalho Eduardo H. Sanchez-Mendoza Adriana R. Schultz Moreira a ďalší

Prispievatelia: Tayana Silva de Carvalho Eduardo H. Sanchez-Mendoza Adriana R. Schultz Moreira a ďalší

Zdroj: Mol Neurobiol

Predmety: Male, 0301 basic medicine, Time Factors, Diet, Reducing, Medizin, Nerve Tissue Proteins, Article, Antioxidants, Brain Ischemia, Mice, 03 medical and health sciences, 0302 clinical medicine, Sirtuin 1, Brain Ischemia/blood [MeSH], Atrophy [MeSH], Mice, Inbred C57BL [MeSH], Brain Ischemia/metabolism [MeSH], Liver/metabolism [MeSH], Nerve Tissue Proteins/metabolism [MeSH], NAD/metabolism [MeSH], Cerebral Infarction/metabolism [MeSH], Sirtuin 1/metabolism [MeSH], Male [MeSH], Neuroprotection [MeSH], Stroke/blood [MeSH], Capillaries/pathology [MeSH], Antioxidants/metabolism [MeSH], Cerebral Infarction/blood [MeSH], Brain/pathology [MeSH], Sirtuin-1, Stroke/pathology [MeSH], Survival Analysis [MeSH], Animals [MeSH], Brain Ischemia/complications [MeSH], Glutathione Peroxidase/metabolism [MeSH], Time Factors [MeSH], Neurological recovery, Neuroprotection, Cerebral Infarction/pathology [MeSH], Calorie restriction, Brain Ischemia/pathology [MeSH], Diet, Reducing [MeSH], Ischemic stroke, Cerebral Infarction/complications [MeSH], Animals, 10. No inequality, Glutathione Peroxidase, Brain, Cerebral Infarction, NAD, Survival Analysis, Capillaries, Mice, Inbred C57BL, Stroke, Liver, Atrophy

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s12035-020-02207-7.pdf
https://pubmed.ncbi.nlm.nih.gov/33200399
https://link.springer.com/content/pdf/10.1007/s12035-020-02207-7.pdf
https://europepmc.org/article/MED/33200399
https://link.springer.com/article/10.1007/s12035-020-02207-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932971
https://resolver.sub.uni-goettingen.de/purl?gro-2/83253
https://repository.publisso.de/resource/frl:6471736

Microglial-specific depletion of TAK1 is neuroprotective in the acute phase after ischemic stroke

Autori: Thomas Zeyen Rozina Noristani Shahin Habib a ďalší

Zdroj: J Mol Med (Berl)
Journal of molecular medicine 98(6), 833-847 (2020). doi:10.1007/s00109-020-01916-9

Predmety: Blood Glucose, Brain Infarction, 0301 basic medicine, Genotype, Cell Survival, MAP Kinase Kinase 4, Mice, Transgenic, Brain Ischemia, Mice, 03 medical and health sciences, Oxygen Consumption, Animals, Cells, Cultured, Mice, Knockout, 0303 health sciences, MAP Kinase Kinase Kinases, Neuroprotection, 3. Good health, Disease Models, Animal, MAP Kinase Kinase Kinases/metabolism [MeSH], Phosphorylation [MeSH], Brain Ischemia/etiology [MeSH], Cell Survival [MeSH], Brain Infarction/pathology [MeSH], Neuroinflammation, Brain Ischemia/metabolism [MeSH], Reperfusion Injury/metabolism [MeSH], Inflammation Mediators/metabolism [MeSH], Oxygen Consumption [MeSH], Cytokines/metabolism [MeSH], Brain Infarction/metabolism [MeSH], Brain Ischemia/diagnosis [MeSH], Original Article, Mice, Transgenic [MeSH], Microglia/metabolism [MeSH], Stroke, Blood Glucose [MeSH], TAK1, Reperfusion Injury/pathology [MeSH], Disease Models, Animal [MeSH], Neuroprotection/genetics [MeSH], Stroke/metabolism [MeSH], Microglia, MAP Kinase Kinase 4/metabolism [MeSH], Animals [MeSH], Disease Susceptibility [MeSH], Mice, Knockout [MeSH], Reperfusion Injury/etiology [MeSH], Mice [MeSH], Stroke/diagnosis [MeSH], Ischemia-reperfusion injury, MAP Kinase Kinase Kinases/genetics [MeSH], p38 Mitogen-Activated Protein Kinases/metabolism [MeSH], Brain Infarction/etiology [MeSH], Genotype [MeSH], Cells, Cultured [MeSH], Biomarkers [MeSH], Stroke/etiology [MeSH], Cytokines, Disease Susceptibility, Inflammation Mediators, Biomarkers

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00109-020-01916-9.pdf
https://pubmed.ncbi.nlm.nih.gov/32382778
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297861
https://link.springer.com/content/pdf/10.1007/s00109-020-01916-9.pdf
https://link.springer.com/article/10.1007/s00109-020-01916-9
https://pubmed.ncbi.nlm.nih.gov/32382778/
https://repository.publisso.de/resource/frl:6441531
https://publications.rwth-aachen.de/record/811441