Suchergebnisse - "Blood Platelets"

Direct Binding of Lyn to GPIbβ Transmits 2-Way GPIb-IX Signaling to Stimulate Platelet Activation and VWF Binding.

Autoren: Zhang Y Liang Y Kazemipour Ashkezari AH et al.

Quelle: Circulation research [Circ Res] 2025 Dec 05; Vol. 137 (12), pp. 1480-1497. Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

MeSH-Schlagworte: Platelet Glycoprotein GPIb-IX Complex*/metabolism , Platelet Glycoprotein GPIb-IX Complex*/genetics , von Willebrand Factor*/metabolism , src-Family Kinases*/metabolism , src-Family Kinases*/genetics , Signal Transduction*/physiology , Platelet Activation*/physiology , Platelet Activation*/drug effects , Blood Platelets*/metabolism , Blood Platelets*/drug effects, Animals ; Mice ; Humans ; Protein Binding ; Platelet Adhesiveness ; Platelet Aggregation/drug effects ; Mice, Inbred C57BL ; Thrombosis ; Male

Platelet mitochondrial complex I and IV activities are not reliable stratification biomarkers in Parkinson's disease.

Autoren: Kverneng SU Mostafavi S Mikhaleva Y et al.

Quelle: Journal of Parkinson's disease [J Parkinsons Dis] 2025 Nov; Vol. 15 (7), pp. 1218-1228. Date of Electronic Publication: 2025 Aug 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101567362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-718X (Electronic) Linking ISSN: 18777171 NLM ISO Abbreviation: J Parkinsons Dis Subsets: MEDLINE

MeSH-Schlagworte: Parkinson Disease*/blood , Parkinson Disease*/diagnosis , Parkinson Disease*/metabolism , Blood Platelets*/enzymology , Blood Platelets*/metabolism , Electron Transport Complex I*/metabolism, Humans ; Male ; Biomarkers/blood ; Biomarkers/metabolism ; Female ; Middle Aged ; Aged ; Muscle, Skeletal/metabolism

Batchwise data analysis with inter-batch feature alignment in large scale platelet lipidomics study using UHPLC-ESI-QTOF-MS/MS by data-independent SWATH acquisition.

Autoren: Dittrich K Fu X Brun A et al.

Quelle: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Dec 15; Vol. 266, pp. 117088. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/methods , Lipidomics*/methods , Blood Platelets*/metabolism , Blood Platelets*/chemistry , Lipids*/analysis , Lipids*/blood, Chromatography, High Pressure Liquid/methods ; Humans ; Spectrometry, Mass, Electrospray Ionization/methods ; Coronary Artery Disease/blood ; Data Analysis

Platelet-hitchhiking triiodothyronine nanoparticles for enhanced therapy of cerebral ischemia-reperfusion injury.

Autoren: Syeda MZ Su G Li Y et al.

Quelle: Journal of colloid and interface science [J Colloid Interface Sci] 2025 Dec 15; Vol. 700 (Pt 1), pp. 138290. Date of Electronic Publication: 2025 Jun 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE

MeSH-Schlagworte: Nanoparticles*/chemistry , Reperfusion Injury*/drug therapy , Reperfusion Injury*/pathology , Reperfusion Injury*/metabolism , Triiodothyronine*/chemistry , Triiodothyronine*/pharmacology , Triiodothyronine*/administration & dosage , Triiodothyronine*/therapeutic use , Blood Platelets*/metabolism , Blood Platelets*/drug effects , Neuroprotective Agents*/chemistry , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/therapeutic use, Animals ; Mice ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism ; Male ; Mice, Inbred C57BL ; Infarction, Middle Cerebral Artery/drug therapy ; Infarction, Middle Cerebral Artery/pathology ; Particle Size ; Humans ; Polysaccharides

Single cell mapping identifies a distinct platelet-phenotype in psoriatic type III inflammation.

Autoren: Kommoss KS Krishnarajah S Bieler T et al.

Quelle: Nature communications [Nat Commun] 2025 Dec 05; Vol. 16 (1), pp. 10881. Date of Electronic Publication: 2025 Dec 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Blood Platelets*/metabolism , Blood Platelets*/immunology , Psoriasis*/blood , Psoriasis*/immunology , Psoriasis*/drug therapy , Psoriasis*/pathology , Inflammation*/blood , Inflammation*/immunology , Single-Cell Analysis*/methods, Humans ; Female ; Male ; Adult ; Phenotype ; Middle Aged ; Flow Cytometry ; Prospective Studies ; Dermatitis, Atopic/blood ; Dermatitis, Atopic/immunology ; Platelet Activation

When it's not Glanzmann thrombasthenia or Bernard-Soulier syndrome: diagnosing other qualitative platelet disorders.

Autoren: Hayward CPM Tasneem S

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 137-146.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Bernard-Soulier Syndrome*/diagnosis , Bernard-Soulier Syndrome*/blood , Bernard-Soulier Syndrome*/genetics , Thrombasthenia*/diagnosis , Thrombasthenia*/blood , Thrombasthenia*/genetics , Blood Platelet Disorders*/diagnosis , Blood Platelet Disorders*/blood , Blood Platelet Disorders*/genetics , Blood Platelets*/metabolism , Blood Platelets*/pathology, Humans ; Platelet Function Tests ; Platelet Aggregation ; Male ; Female

Interplay Between Thrombospondin-1 and CD36 Modulates Platelet-RBC Interaction in Thrombosis and Abdominal Aneurysm Formation.

Autoren: Krott KJ Feige T Bosbach A et al.

Quelle: Circulation research [Circ Res] 2025 Dec 05; Vol. 137 (12), pp. 1459-1479. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

MeSH-Schlagworte: Thrombospondin 1*/genetics , Thrombospondin 1*/metabolism , Thrombospondin 1*/blood , Thrombospondin 1*/deficiency , CD36 Antigens*/genetics , CD36 Antigens*/metabolism , CD36 Antigens*/blood , CD36 Antigens*/deficiency , Aortic Aneurysm, Abdominal*/blood , Aortic Aneurysm, Abdominal*/metabolism , Aortic Aneurysm, Abdominal*/pathology , Aortic Aneurysm, Abdominal*/genetics , Thrombosis*/metabolism , Thrombosis*/blood , Thrombosis*/pathology , Thrombosis*/genetics , Blood Platelets*/metabolism , Erythrocytes*/metabolism, Animals ; Humans ; Mice, Knockout ; Mice ; Male ; Mice, Inbred C57BL ; Disease Models, Animal ; Female ; Signal Transduction ; Platelet Activation

Evaluation of platelet dense granules by transmission electron microscopy in healthy pediatric donors and pediatric patients with suspected platelet disorders.

Autoren: Greenmyer JR Chen D Howell KG et al.

Quelle: Platelets [Platelets] 2025 Dec; Vol. 36 (1), pp. 2590752. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE

MeSH-Schlagworte: Blood Platelet Disorders*/blood , Blood Platelet Disorders*/diagnosis , Blood Platelets*/ultrastructure , Blood Platelets*/metabolism , Microscopy, Electron, Transmission*/methods , Cytoplasmic Granules*/ultrastructure , Cytoplasmic Granules*/metabolism, Humans ; Child ; Female ; Male ; Adolescent ; Child, Preschool

Liquiritigenin attenuates thrombosis by inhibiting P2Y 12 R-mediated Src/PLCγ2 signaling and cytoplasmic Ca ²⁺ mobilization in platelets.

Autoren: Cheng L Yu T Xue H et al.

Quelle: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Dec; Vol. 149, pp. 157553. Date of Electronic Publication: 2025 Nov 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

MeSH-Schlagworte: Thrombosis*/drug therapy , Blood Platelets*/drug effects , Blood Platelets*/metabolism , Flavanones*/pharmacology , Receptors, Purinergic P2Y12*/metabolism, Humans ; Animals ; Human Umbilical Vein Endothelial Cells/drug effects ; Calcium/metabolism ; Phospholipase C gamma/metabolism ; Signal Transduction/drug effects ; Platelet Activation/drug effects ; src-Family Kinases/metabolism ; Mice ; Male ; Glycyrrhiza/chemistry ; Coculture Techniques

Complement C3 inhibition reduces complement activation in clinical platelet concentrates but does not counteract platelet storage lesions.

Autoren: Andersson LI Sandgren P Sjöström DJ et al.

Quelle: Platelets [Platelets] 2025 Dec; Vol. 36 (1), pp. 2513298. Date of Electronic Publication: 2025 Jun 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE

MeSH-Schlagworte: Blood Platelets*/metabolism , Blood Platelets*/drug effects , Complement C3*/antagonists & inhibitors , Complement C3*/metabolism , Complement Activation*/drug effects , Blood Preservation*/methods, Humans ; Platelet Activation/drug effects

High Dose of Antithrombin Suppresses Neutrophil Extracellular Trap Formation in Human Neutrophils In Vitro Following Lipopolysaccharide- and Platelet-Induced Stimulation.

Autoren: Aoyama-Ishikawa M Higashi H Murakami H et al.

Quelle: Surgical infections [Surg Infect (Larchmt)] 2025 Dec; Vol. 26 (10), pp. 762-769. Date of Electronic Publication: 2025 Sep 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9815642 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8674 (Electronic) Linking ISSN: 10962964 NLM ISO Abbreviation: Surg Infect (Larchmt) Subsets: MEDLINE

MeSH-Schlagworte: Extracellular Traps*/drug effects , Extracellular Traps*/metabolism , Lipopolysaccharides*/pharmacology , Neutrophils*/drug effects , Neutrophils*/immunology , Antithrombins*/pharmacology , Antithrombins*/administration & dosage , Blood Platelets*/drug effects , Blood Platelets*/immunology, Humans ; Protein-Arginine Deiminase Type 4 ; Male ; Adult ; Female ; Cells, Cultured

Brutons tyrosine kinase inhibitor Zanubrutinib modulates Fc gamma receptors to inhibit platelet destruction for alleviation of refractory immune thrombocytopenia.

Autoren: Yang XX Yao GL Yang YJ et al.

Quelle: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2545078. Date of Electronic Publication: 2025 Oct 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH-Schlagworte: Pyrazoles*/pharmacology , Pyrazoles*/therapeutic use , Purpura, Thrombocytopenic, Idiopathic*/drug therapy , Purpura, Thrombocytopenic, Idiopathic*/metabolism , Purpura, Thrombocytopenic, Idiopathic*/blood , Receptors, IgG*/metabolism , Blood Platelets*/metabolism , Blood Platelets*/drug effects , Blood Platelets*/pathology , Piperidines*/pharmacology , Piperidines*/therapeutic use , Pyrimidines*/pharmacology , Pyrimidines*/therapeutic use , Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Adult ; Aged ; Tyrosine Kinase Inhibitors

Effect of aspirin dosage on oxidative stress and platelet reactivity in patients undergoing coronary artery bypass grafting (APRICOT): randomized controlled trial.

Autoren: Gąsecka A Kaczorowski R Pomykała K et al.

Quelle: Platelets [Platelets] 2025 Dec; Vol. 36 (1), pp. 2457415. Date of Electronic Publication: 2025 Feb 05.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE

MeSH-Schlagworte: Aspirin*/pharmacology , Aspirin*/therapeutic use , Aspirin*/administration & dosage , Oxidative Stress*/drug effects , Coronary Artery Bypass*/methods , Blood Platelets*/drug effects , Blood Platelets*/metabolism , Platelet Activation*/drug effects , Platelet Aggregation Inhibitors*/therapeutic use , Platelet Aggregation Inhibitors*/pharmacology, Humans ; Male ; Female ; Middle Aged ; Aged

The effect of physical cues on platelet storage lesion.

Autoren: Cheng L Wang L Wang S et al.

Quelle: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2450573. Date of Electronic Publication: 2025 Jan 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH-Schlagworte: Blood Platelets*/metabolism , Blood Platelets*/cytology , Blood Preservation*/methods, Humans ; Platelet Activation ; Centrifugation ; Male

Psychotropic and neurodegenerative drugs modulate platelet activity via the PAF pathway.

Autoren: Kosidou S Zannas Z Ofrydopoulou A et al.

Quelle: Neurochemistry international [Neurochem Int] 2025 Dec; Vol. 191, pp. 106073. Date of Electronic Publication: 2025 Oct 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE

MeSH-Schlagworte: Platelet Activating Factor*/metabolism , Psychotropic Drugs*/pharmacology , Blood Platelets*/drug effects , Blood Platelets*/metabolism , Platelet Activation*/drug effects , Platelet Activation*/physiology , Neuroprotective Agents*/pharmacology, Humans ; Platelet Aggregation/drug effects ; Platelet Aggregation/physiology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Antipsychotic Agents/pharmacology ; Neurodegenerative Diseases/drug therapy

Evaluation of the effect of 48 weeks of BIC/F/TAF and DRV/c/F/TAF on platelet function in the context of rapid ART start.

Autoren: Khawaja AA Whitlock G Fidler S et al.

Quelle: HIV research & clinical practice [HIV Res Clin Pract] 2025 Dec; Vol. 26 (1), pp. 2447015. Date of Electronic Publication: 2025 Jan 07.

Publikationsart: Journal Article; Randomized Controlled Trial; Multicenter Study

Info zur Zeitschrift: Publisher: Taylor & Francis Group Country of Publication: England NLM ID: 101738312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2578-7470 (Electronic) Linking ISSN: 25787470 NLM ISO Abbreviation: HIV Res Clin Pract Subsets: MEDLINE

MeSH-Schlagworte: Blood Platelets*/drug effects , Blood Platelets*/physiology, Humans ; Male ; Female ; Adult ; Middle Aged ; HIV Infections/drug therapy ; Platelet Aggregation/drug effects ; Platelet Activation/drug effects ; Viral Load/drug effects ; Platelet Function Tests/methods ; Anti-HIV Agents/therapeutic use ; United Kingdom

Identification of UDP-Glucuronosyltransferase mRNA in human platelets: differential levels in smokers and non-smokers.

Autoren: Jarrar Y Almansour M Abulebdeh D et al.

Quelle: Platelets [Platelets] 2025 Dec; Vol. 36 (1), pp. 2536306. Date of Electronic Publication: 2025 Jul 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE

MeSH-Schlagworte: Glucuronosyltransferase*/genetics , Glucuronosyltransferase*/metabolism , Blood Platelets*/metabolism , Blood Platelets*/enzymology , RNA, Messenger*/genetics , RNA, Messenger*/metabolism , Smokers* , Non-Smokers* , Smoking*/genetics, Humans ; Male ; Female ; Adult ; Middle Aged

Effects of Artificial Lung and Roller Pump on Platelet Morphology and Activation During Simulated Extracorporeal Circulation.

Autoren: Arao H Kozuma Y Furugaki T et al.

Quelle: International journal of laboratory hematology [Int J Lab Hematol] 2025 Dec; Vol. 47 (6), pp. 1128-1136. Date of Electronic Publication: 2025 Jun 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 101300213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-553X (Electronic) Linking ISSN: 17515521 NLM ISO Abbreviation: Int J Lab Hematol Subsets: MEDLINE

MeSH-Schlagworte: Platelet Activation* , Extracorporeal Circulation*/instrumentation , Extracorporeal Circulation*/methods , Extracorporeal Circulation*/adverse effects , Blood Platelets*/metabolism , Blood Platelets*/cytology, Humans ; Male ; Adult ; Female ; Platelet Aggregation ; Platelet Membrane Glycoprotein IIb/metabolism ; Platelet Glycoprotein GPIb-IX Complex/metabolism

A multi-color flow cytometric method for characterizing murine reticulated platelets using SYTO 13.

Autoren: Hamad MA Krauel K Schanze N et al.

Quelle: Platelets [Platelets] 2025 Dec; Vol. 36 (1), pp. 2489020. Date of Electronic Publication: 2025 Apr 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9208117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1369-1635 (Electronic) Linking ISSN: 09537104 NLM ISO Abbreviation: Platelets Subsets: MEDLINE

MeSH-Schlagworte: Blood Platelets*/metabolism , Blood Platelets*/cytology , Flow Cytometry*/methods, Animals ; Mice ; Platelet Activation ; P-Selectin/metabolism

Reticulated platelets in coronary artery disease: a multidimensional approach unveils prothrombotic signalling and novel therapeutic targets.

Autoren: Kirmes K Han J Klug M et al.

Quelle: European heart journal [Eur Heart J] 2025 Dec 01; Vol. 46 (45), pp. 4901-4917.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE

MeSH-Schlagworte: Coronary Artery Disease*/drug therapy , Coronary Artery Disease*/blood , Blood Platelets*/metabolism , Blood Platelets*/physiology , Thrombosis*, Humans ; Male ; Signal Transduction/physiology ; Female ; Middle Aged ; Platelet Aggregation Inhibitors/therapeutic use ; Platelet Aggregation Inhibitors/pharmacology ; Aged ; Platelet Membrane Glycoproteins/metabolism ; Platelet Activation/physiology ; Proteomics ; Gene Expression Profiling