Suchergebnisse - "Bacterial Proteins (mesh)"

Biosensor-driven strain engineering reveals key cellular processes for maximizing isoprenol production in Pseudomonas putida

Autoren: Menasalvas, Javier Kulakowski, Shawn Chen, Yan et al.

Quelle: Science Advances. 11(43)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), 3106 Industrial Biotechnology (for-2020), Biotechnology (rcdc), Bioengineering (rcdc), Pseudomonas putida (mesh), Biosensing Techniques (mesh), Metabolic Engineering (mesh), Hemiterpenes (mesh), Signal Transduction (mesh), Synthetic Biology (mesh), Histidine Kinase (mesh), Alcohol Dehydrogenase (mesh), Bacterial Proteins (mesh), Pseudomonas putida (mesh), Hemiterpenes (mesh), Alcohol Dehydrogenase (mesh), Bacterial Proteins (mesh), Biosensing Techniques (mesh), Signal Transduction (mesh), Synthetic Biology (mesh), Metabolic Engineering (mesh), Histidine Kinase (mesh), Pseudomonas putida (mesh), Biosensing Techniques (mesh), Metabolic Engineering (mesh), Hemiterpenes (mesh), Signal Transduction (mesh), Synthetic Biology (mesh), Histidine Kinase (mesh), Alcohol Dehydrogenase (mesh), Bacterial Proteins (mesh)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/29n9q5d3
https://escholarship.org/content/qt29n9q5d3/qt29n9q5d3.pdf

RB-TnSeq elucidates dicarboxylic-acid-specific catabolism in β-proteobacteria for improved plastic monomer upcycling

Autoren: Pearson, Allison N Lynch, Julie M Ho, Cindy N et al.

Quelle: Applied and Environmental Microbiology. 91(10)

Schlagwörter: 31 Biological Sciences (for-2020), 3106 Industrial Biotechnology (for-2020), Prevention (rcdc), Genetics (rcdc), 12 Responsible Consumption and Production (sdg), Dicarboxylic Acids (mesh), Plastics (mesh), Betaproteobacteria (mesh), Bacterial Proteins (mesh), Fatty Acids (mesh), DNA Transposable Elements (mesh), functional genomics, dicarboxylic acids, plastics upcyling, Betaproteobacteria (mesh), Dicarboxylic Acids (mesh), Plastics (mesh), Fatty Acids (mesh), Bacterial Proteins (mesh), DNA Transposable Elements (mesh), dicarboxylic acids, functional genomics, plastics upcyling, Dicarboxylic Acids (mesh), Plastics (mesh), Betaproteobacteria (mesh), Bacterial Proteins (mesh), Fatty Acids (mesh), DNA Transposable Elements (mesh), Microbiology (science-metrix), 3107 Microbiology (for-2020), 3207 Medical microbiology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/2k13p644
https://escholarship.org/content/qt2k13p644/qt2k13p644.pdf

Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari belonging to glycoside hydrolase family 10

Autoren: Torosian, Nicole Covington, Jonathan K Cook, Allison M et al.

Quelle: FEBS Open Bio. 15(10)

Schlagwörter: 31 Biological Sciences (for-2020), 3105 Genetics (for-2020), Glycoside Hydrolases (mesh), Xylans (mesh), Endo-1, 4-beta Xylanases (mesh), Phylogeny (mesh), Hydrogen-Ion Concentration (mesh), Substrate Specificity (mesh), Bacterial Proteins (mesh), Armatimonadota, GH10, glycoside hydrolase, hyperthermophile, xylanase, Glycoside Hydrolases (mesh), Endo-1, 4-beta Xylanases (mesh), Xylans (mesh), Bacterial Proteins (mesh), Phylogeny (mesh), Substrate Specificity (mesh), Hydrogen-Ion Concentration (mesh), Armatimonadota, GH10, glycoside hydrolase, hyperthermophile, xylanase, Glycoside Hydrolases (mesh), Xylans (mesh), Endo-1, 4-beta Xylanases (mesh), Phylogeny (mesh), Hydrogen-Ion Concentration (mesh), Substrate Specificity (mesh), Bacterial Proteins (mesh), 3101 Biochemistry and cell biology (for-2020), 3404 Medicinal and biomolecular chemistry (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/5jk3x3xk
https://escholarship.org/content/qt5jk3x3xk/qt5jk3x3xk.pdf

Yersinia ruckeri YRB periplasmic binding protein YiuA selectively recognizes a Fe( iii )-mono-catecholate siderophore

Autoren: Thomsen, Emil Thompson, Seán Stow, Parker R et al.

Quelle: Chemical Communications. 61(90)

Schlagwörter: 3402 Inorganic Chemistry (for-2020), 34 Chemical Sciences (for-2020), Yersinia (mesh), Ferric Compounds (mesh), Bacterial Proteins (mesh), Periplasmic Binding Proteins (mesh), Siderophores (mesh), Crystallography, X-Ray (mesh), Models, Molecular (mesh), 03 Chemical Sciences (for), Organic Chemistry (science-metrix), 34 Chemical sciences (for-2020), 40 Engineering (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/1nv1r6t7
https://escholarship.org/content/qt1nv1r6t7/qt1nv1r6t7.pdf

Periplasmic Binding Protein YiuA Enables Yersinia pestis to Scavenge Fe(III)-Catechol Siderophores

Autoren: Thomsen, Emil Stow, Parker Roth, Daniel et al.

Quelle: ACS Infectious Diseases. 11(9)

Schlagwörter: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), Biodefense (rcdc), Vector-Borne Diseases (rcdc), Emerging Infectious Diseases (rcdc), Infectious Diseases (rcdc), Siderophores (mesh), Yersinia pestis (mesh), Catechols (mesh), Ferric Compounds (mesh), Bacterial Proteins (mesh), Periplasmic Binding Proteins (mesh), Enterobactin (mesh), Iron (mesh), Protein Binding (mesh), Yersinia pestis, siderophore, periplasmic-binding-protein, chirality, iron-uptake, Yersinia pestis (mesh), Iron (mesh), Ferric Compounds (mesh), Catechols (mesh), Enterobactin (mesh), Bacterial Proteins (mesh), Periplasmic Binding Proteins (mesh), Siderophores (mesh), Protein Binding (mesh), Yersinia pestis, chirality, iron-uptake, periplasmic-binding-protein, siderophore, Siderophores (mesh), Yersinia pestis (mesh), Catechols (mesh), Ferric Compounds (mesh), Bacterial Proteins (mesh), Periplasmic Binding Proteins (mesh), Enterobactin (mesh), Iron (mesh), Protein Binding (mesh), 1108 Medical Microbiology (for), 3207 Medical microbiology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/3x1753fv
https://escholarship.org/content/qt3x1753fv/qt3x1753fv.pdf

Rapid two-step target capture ensures efficient CRISPR-Cas9-guided genome editing

Autoren: Shi, Honglue Al-Sayyad, Noor Wasko, Kevin M et al.

Quelle: Molecular Cell. 85(9)

Schlagwörter: 31 Biological Sciences (for-2020), 3102 Bioinformatics and Computational Biology (for-2020), Genetics (rcdc), Emerging Infectious Diseases (rcdc), Infectious Diseases (rcdc), Biotechnology (rcdc), 1.1 Normal biological development and functioning (hrcs-rac), Generic health relevance (hrcs-hc), CRISPR-Cas Systems (mesh), Gene Editing (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), Streptococcus pyogenes (mesh), Humans (mesh), CRISPR-Associated Protein 9 (mesh), HEK293 Cells (mesh), Bacterial Proteins (mesh), DNA (mesh), Nucleotide Motifs (mesh), Humans (mesh), Streptococcus pyogenes (mesh), Bacterial Proteins (mesh), DNA (mesh), HEK293 Cells (mesh), Nucleotide Motifs (mesh), CRISPR-Cas Systems (mesh), Gene Editing (mesh), CRISPR-Associated Protein 9 (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), CRISPR-Cas9, DNA recognition, DNA unwinding, biochemistry, biophysics, genome editing, kinetic models, protospacer-adjacent motifs, single-molecule manipulation, target search, CRISPR-Cas Systems (mesh), Gene Editing (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), Streptococcus pyogenes (mesh), Humans (mesh), CRISPR-Associated Protein 9 (mesh), HEK293 Cells (mesh), Bacterial Proteins (mesh), DNA (mesh), Nucleotide Motifs (mesh), 06 Biological Sciences (for), 11 Medical and Health Sciences (for), Developmental Biology (science-metrix), 31 Biological sciences (for-2020), 32 Biomedical and clinical sciences (for-2020), 42 Health sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/53j8s6ck
https://escholarship.org/content/qt53j8s6ck/qt53j8s6ck.pdf

Late gene regulation by the alternative sigma factors of Chlamydia trachomatis

Autoren: Rizvi, Syed MA Densi, Asha Hakiem, Owais R et al.

Quelle: mSystems. 10(7)

Schlagwörter: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 31 Biological Sciences (for-2020), Genetics (rcdc), Sexually Transmitted Infections (rcdc), Infectious Diseases (rcdc), Human Genome (rcdc), Biotechnology (rcdc), 3 Good Health and Well Being (sdg), Chlamydia trachomatis (mesh), Sigma Factor (mesh), Gene Expression Regulation, Bacterial (mesh), Promoter Regions, Genetic (mesh), Bacterial Proteins (mesh), Humans (mesh), DNA-Directed RNA Polymerases (mesh), transcription, gene expression, regulon, RNA polymerase, RNA-seq, ChIP-seq, Humans (mesh), Chlamydia trachomatis (mesh), DNA-Directed RNA Polymerases (mesh), Bacterial Proteins (mesh), Sigma Factor (mesh), Gene Expression Regulation, Bacterial (mesh), Promoter Regions, Genetic (mesh), ChIP-seq, RNA polymerase, RNA-seq, gene expression, regulon, transcription, Chlamydia trachomatis (mesh), Sigma Factor (mesh), Gene Expression Regulation, Bacterial (mesh), Promoter Regions, Genetic (mesh), Bacterial Proteins (mesh), Humans (mesh), DNA-Directed RNA Polymerases (mesh)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/7nm1x259
https://escholarship.org/content/qt7nm1x259/qt7nm1x259.pdf

Directed evolution expands CRISPR–Cas12a genome-editing capacity

Autoren: Ma, Enbo Chen, Kai Shi, Honglue et al.

Quelle: Nucleic Acids Research. 53(13)

Schlagwörter: 31 Biological Sciences (for-2020), 3105 Genetics (for-2020), Biotechnology (rcdc), Human Genome (rcdc), Genetics (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), CRISPR-Cas Systems (mesh), Gene Editing (mesh), Humans (mesh), CRISPR-Associated Proteins (mesh), Directed Molecular Evolution (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), Genome, Human (mesh), Humans (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), Directed Molecular Evolution (mesh), Genome, Human (mesh), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), Gene Editing (mesh), CRISPR-Cas Systems (mesh), Gene Editing (mesh), Humans (mesh), CRISPR-Associated Proteins (mesh), Directed Molecular Evolution (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), Genome, Human (mesh), 05 Environmental Sciences (for), 06 Biological Sciences (for), 08 Information and Computing Sciences (for), Developmental Biology (science-metrix), 31 Biological sciences (for-2020), 34 Chemical sciences (for-2020), 41 Environmental sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/7n89c79w
https://escholarship.org/content/qt7n89c79w/qt7n89c79w.pdf

Enzymatic carbon–fluorine bond cleavage by human gut microbes

Autoren: Probst, Silke I Felder, Florian D Poltorak, Victoria et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America. 122(24)

Schlagwörter: 4102 Ecological Applications (for-2020), 31 Biological Sciences (for-2020), 3101 Biochemistry and Cell Biology (for-2020), 3107 Microbiology (for-2020), 41 Environmental Sciences (for-2020), Microbiome (rcdc), Machine Learning and Artificial Intelligence (rcdc), Oral and gastrointestinal (hrcs-hc), Humans (mesh), Gastrointestinal Microbiome (mesh), Carbon (mesh), Fluorine (mesh), Halogenation (mesh), Bacterial Proteins (mesh), Hydrolases (mesh), Molecular Dynamics Simulation (mesh), defluorination, haloacid dehalogenases, molecular dynamics, protein engineering, human gut microbiome, Humans (mesh), Carbon (mesh), Fluorine (mesh), Hydrolases (mesh), Bacterial Proteins (mesh), Halogenation (mesh), Molecular Dynamics Simulation (mesh), Gastrointestinal Microbiome (mesh), defluorination, haloacid dehalogenases, human gut microbiome, molecular dynamics, protein engineering, Humans (mesh), Gastrointestinal Microbiome (mesh), Carbon (mesh), Fluorine (mesh), Halogenation (mesh), Bacterial Proteins (mesh), Hydrolases (mesh), Molecular Dynamics Simulation (mesh)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/42t1n3dc
https://escholarship.org/content/qt42t1n3dc/qt42t1n3dc.pdf

Serial-femtosecond crystallography reveals how a phytochrome variant couples chromophore and protein structural changes

Autoren: Sauthof, Luisa Szczepek, Michal Schmidt, Andrea et al.

Quelle: Science Advances. 11(22)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), 34 Chemical Sciences (for-2020), 3406 Physical Chemistry (for-2020), 3407 Theoretical and Computational Chemistry (for-2020), Phytochrome (mesh), Crystallography, X-Ray (mesh), Protein Conformation (mesh), Models, Molecular (mesh), Bacterial Proteins (mesh), Phytochrome (mesh), Bacterial Proteins (mesh), Crystallography, X-Ray (mesh), Protein Conformation (mesh), Models, Molecular (mesh), Phytochrome (mesh), Crystallography, X-Ray (mesh), Protein Conformation (mesh), Models, Molecular (mesh), Bacterial Proteins (mesh)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/9h52g4jx
https://escholarship.org/content/qt9h52g4jx/qt9h52g4jx.pdf

Architecture of Pseudomonas aeruginosa glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases

Autoren: Fenwick, Michael K Mayclin, Stephen J Seibold, Steve et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America. 122(19)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), Infectious Diseases (rcdc), Pseudomonas aeruginosa (mesh), Glutamate-tRNA Ligase (mesh), Binding Sites (mesh), Protein Multimerization (mesh), Models, Molecular (mesh), RNA, Transfer (mesh), Bacterial Proteins (mesh), Anticodon (mesh), Amino Acyl-tRNA Synthetases (mesh), Catalytic Domain (mesh), Pseudomonas aeruginosa (mesh), Amino Acyl-tRNA Synthetases (mesh), Glutamate-tRNA Ligase (mesh), Bacterial Proteins (mesh), RNA, Transfer (mesh), Anticodon (mesh), Binding Sites (mesh), Catalytic Domain (mesh), Models, Molecular (mesh), Protein Multimerization (mesh), aminoacyl-tRNA synthetase, oligomerization, protein translation, Pseudomonas aeruginosa (mesh), Glutamate-tRNA Ligase (mesh), Binding Sites (mesh), Protein Multimerization (mesh), Models, Molecular (mesh), RNA, Transfer (mesh), Bacterial Proteins (mesh), Anticodon (mesh), Amino Acyl-tRNA Synthetases (mesh), Catalytic Domain (mesh)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/4xb2t324
https://escholarship.org/content/qt4xb2t324/qt4xb2t324.pdf

Soft X-ray tomography reveals variations in B. subtilis biofilm structure upon tasA deletion

Autoren: Chatzimpinou, Anthoula Diehl, Anne Harhoff, A Tobias et al.

Quelle: npj Biofilms and Microbiomes. 11(1)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), Biomedical Imaging (rcdc), Biofilms (mesh), Bacillus subtilis (mesh), Bacterial Proteins (mesh), Tomography, X-Ray (mesh), Imaging, Three-Dimensional (mesh), Gene Deletion (mesh), Extracellular Matrix (mesh), Extracellular Matrix (mesh), Biofilms (mesh), Bacillus subtilis (mesh), Bacterial Proteins (mesh), Imaging, Three-Dimensional (mesh), Tomography, X-Ray (mesh), Gene Deletion (mesh), Biofilms (mesh), Bacillus subtilis (mesh), Bacterial Proteins (mesh), Tomography, X-Ray (mesh), Imaging, Three-Dimensional (mesh), Gene Deletion (mesh), Extracellular Matrix (mesh), 3103 Ecology (for-2020), 3107 Microbiology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/1zc817v5
https://escholarship.org/content/qt1zc817v5/qt1zc817v5.pdf

Xpert MTB/RIF Ultra-resistant and MTBDRplus-susceptible rifampicin results in people with tuberculosis: utility of FluoroType MTBDR and deep sequencing

Autoren: Ghebrekristos, Yonas Ahmed, Aysha Beylis, Natalie et al.

Quelle: Antimicrobial Agents and Chemotherapy. 69(3)

Schlagwörter: 31 Biological Sciences (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Lung (rcdc), Infectious Diseases (rcdc), Tuberculosis (rcdc), Emerging Infectious Diseases (rcdc), Rare Diseases (rcdc), Orphan Drug (rcdc), Genetics (rcdc), Biodefense (rcdc), Antimicrobial Resistance (rcdc), Infection (hrcs-hc), 3 Good Health and Well Being (sdg), Rifampin (mesh), Humans (mesh), Mycobacterium tuberculosis (mesh), High-Throughput Nucleotide Sequencing (mesh), Microbial Sensitivity Tests (mesh), Tuberculosis, Multidrug-Resistant (mesh), Sputum (mesh), Bacterial Proteins (mesh), Antitubercular Agents (mesh), DNA-Directed RNA Polymerases (mesh), South Africa (mesh), Catalase (mesh), Drug Resistance, Bacterial (mesh), Oxidoreductases (mesh), tuberculosis, diagnosis, rifampicin susceptibility, heteroresistance, Sputum (mesh), Humans (mesh), Mycobacterium tuberculosis (mesh), Tuberculosis, Multidrug-Resistant (mesh), Rifampin (mesh), Oxidoreductases (mesh), Catalase (mesh), DNA-Directed RNA Polymerases (mesh), Bacterial Proteins (mesh), Antitubercular Agents (mesh), Microbial Sensitivity Tests (mesh), Drug Resistance, Bacterial (mesh), South Africa (mesh), High-Throughput Nucleotide Sequencing (mesh), diagnosis, heteroresistance, rifampicin susceptibility, tuberculosis, Rifampin (mesh), Humans (mesh), Mycobacterium tuberculosis (mesh), High-Throughput Nucleotide Sequencing (mesh), Microbial Sensitivity Tests (mesh), Tuberculosis, Multidrug-Resistant (mesh), Sputum (mesh), Bacterial Proteins (mesh), Antitubercular Agents (mesh), DNA-Directed RNA Polymerases (mesh), South Africa (mesh), Catalase (mesh), Drug Resistance, Bacterial (mesh), Oxidoreductases (mesh), 0605 Microbiology (for), 1108 Medical Microbiology (for), 1115 Pharmacology and Pharmaceutical Sciences (for), Microbiology (science-metrix), 3107 Microbiology (for-2020), 3207 Medical microbiology (for-2020), 3214 Pharmacology and pharmaceutical sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/7zx169xr
https://escholarship.org/content/qt7zx169xr/qt7zx169xr.pdf

CRISPR-Cas12a bends DNA to destabilize base pairs during target interrogation

Autoren: Soczek, Katarzyna M Cofsky, Joshua C Tuck, Owen T et al.

Quelle: Nucleic Acids Research. 53(2)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 3102 Bioinformatics and Computational Biology (for-2020), 31 Biological Sciences (for-2020), Genetics (rcdc), 1.1 Normal biological development and functioning (hrcs-rac), 2.1 Biological and endogenous factors (hrcs-rac), Generic health relevance (hrcs-hc), 3 Good Health and Well Being (sdg), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), DNA (mesh), Base Pairing (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), Nucleic Acid Conformation (mesh), Gene Editing (mesh), Cryoelectron Microscopy (mesh), Models, Molecular (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), DNA (mesh), Cryoelectron Microscopy (mesh), Nucleic Acid Conformation (mesh), Base Pairing (mesh), Models, Molecular (mesh), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), Gene Editing (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), DNA (mesh), Base Pairing (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), Nucleic Acid Conformation (mesh), Gene Editing (mesh), Cryoelectron Microscopy (mesh), Models, Molecular (mesh), 05 Environmental Sciences (for), 06 Biological Sciences (for), 08 Information and Computing Sciences (for), Developmental Biology (science-metrix), 31 Biological sciences (for-2020), 34 Chemical sciences (for-2020), 41 Environmental sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/7bn1f54g
https://escholarship.org/content/qt7bn1f54g/qt7bn1f54g.pdf

Helicobacter pylori luxS mutants cause hyperinflammatory responses during chronic infection

Autoren: Yang, Christina Rodriguez y Baena, Alessandra Manso, Bryce A et al.

Quelle: Microbiology Spectrum. 13(1)

Schlagwörter: 3107 Microbiology (for-2020), 31 Biological Sciences (for-2020), Emerging Infectious Diseases (rcdc), Rare Diseases (rcdc), Digestive Diseases (rcdc), Cancer (rcdc), Digestive Diseases - (Peptic Ulcer) (rcdc), Infectious Diseases (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Infection (hrcs-hc), Helicobacter pylori (mesh), Carbon-Sulfur Lyases (mesh), Helicobacter Infections (mesh), Bacterial Proteins (mesh), Quorum Sensing (mesh), Homoserine (mesh), Mutation (mesh), Lactones (mesh), Animals (mesh), Mice (mesh), Inflammation (mesh), CD4-Positive T-Lymphocytes (mesh), Persistent Infection (mesh), Humans (mesh), Female (mesh), Gastritis (mesh), Mice, Inbred C57BL (mesh), inflammation, chronic infection, ulcer, gastric cancer, quorum sensing, CD4-Positive T-Lymphocytes (mesh), Animals (mesh), Mice, Inbred C57BL (mesh), Humans (mesh), Mice (mesh), Helicobacter pylori (mesh), Helicobacter Infections (mesh), Gastritis (mesh), Inflammation (mesh), Lactones (mesh), Carbon-Sulfur Lyases (mesh), Homoserine (mesh), Bacterial Proteins (mesh), Mutation (mesh), Female (mesh), Quorum Sensing (mesh), Persistent Infection (mesh), chronic infection, gastric cancer, inflammation, quorum sensing, ulcer, Helicobacter pylori (mesh), Carbon-Sulfur Lyases (mesh), Helicobacter Infections (mesh), Bacterial Proteins (mesh), Quorum Sensing (mesh), Homoserine (mesh), Mutation (mesh), Lactones (mesh), Animals (mesh), Mice (mesh), Inflammation (mesh), CD4-Positive T-Lymphocytes (mesh), Persistent Infection (mesh), Humans (mesh), Female (mesh), Gastritis (mesh), Mice, Inbred C57BL (mesh), 3107 Microbiology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/9m14t1jd
https://escholarship.org/content/qt9m14t1jd/qt9m14t1jd.pdf

Carbohydrate Deacetylase Unique to Gut Microbe Bacteroides Reveals Atypical Structure

Autoren: Schwartz, Lilith A Norman, Jordan O Hasan, Sharika et al.

Quelle: Biochemistry. 64(1)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), Microbiome (rcdc), Autoimmune Disease (rcdc), Digestive Diseases (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), 1.1 Normal biological development and functioning (hrcs-rac), Oral and gastrointestinal (hrcs-hc), Bacteroides (mesh), Crystallography, X-Ray (mesh), Gastrointestinal Microbiome (mesh), Amidohydrolases (mesh), Humans (mesh), Models, Molecular (mesh), Bacterial Proteins (mesh), Catalytic Domain (mesh), Protein Conformation (mesh), Humans (mesh), Bacteroides (mesh), Amidohydrolases (mesh), Bacterial Proteins (mesh), Crystallography, X-Ray (mesh), Catalytic Domain (mesh), Protein Conformation (mesh), Models, Molecular (mesh), Gastrointestinal Microbiome (mesh), Bacteroides (mesh), Crystallography, X-Ray (mesh), Gastrointestinal Microbiome (mesh), Amidohydrolases (mesh), Humans (mesh), Models, Molecular (mesh), Bacterial Proteins (mesh), Catalytic Domain (mesh), Protein Conformation (mesh), 0304 Medicinal and Biomolecular Chemistry (for), 0601 Biochemistry and Cell Biology (for), 1101 Medical Biochemistry and Metabolomics (for), Biochemistry & Molecular Biology (science-metrix), 3101 Biochemistry and cell biology (for-2020), 3205 Medical biochemistry and metabolomics (for-2020), 3404 Medicinal and biomolecular chemistry (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/3r1306gt
https://escholarship.org/content/qt3r1306gt/qt3r1306gt.pdf

Reconstitution of circadian clock in synthetic cells reveals principles of timekeeping

Autoren: Li, Alexander Zhan Tu LiWang, Andy Subramaniam, Anand Bala

Quelle: Nature Communications. 16(1)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), Neurosciences (rcdc), Sleep Research (rcdc), 1.1 Normal biological development and functioning (hrcs-rac), Generic health relevance (hrcs-hc), Circadian Clocks (mesh), Bacterial Proteins (mesh), Circadian Rhythm Signaling Peptides and Proteins (mesh), Unilamellar Liposomes (mesh), Artificial Cells (mesh), Circadian Rhythm (mesh), Synechococcus (mesh), Synechococcus (mesh), Bacterial Proteins (mesh), Circadian Rhythm (mesh), Unilamellar Liposomes (mesh), Circadian Rhythm Signaling Peptides and Proteins (mesh), Circadian Clocks (mesh), Artificial Cells (mesh), Circadian Clocks (mesh), Bacterial Proteins (mesh), Circadian Rhythm Signaling Peptides and Proteins (mesh), Unilamellar Liposomes (mesh), Artificial Cells (mesh), Circadian Rhythm (mesh), Synechococcus (mesh)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/26t6m8g0
https://escholarship.org/content/qt26t6m8g0/qt26t6m8g0.pdf

Dynamic basis of supercoiling-dependent DNA interrogation by Cas12a via R-loop intermediates

Autoren: Aris, Kevin DP Cofsky, Joshua C Shi, Honglue et al.

Quelle: Nature Communications. 16(1)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), Genetics (rcdc), Bioengineering (rcdc), Generic health relevance (hrcs-hc), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), DNA, Superhelical (mesh), R-Loop Structures (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), Kinetics (mesh), DNA (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), DNA (mesh), DNA, Superhelical (mesh), Kinetics (mesh), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), R-Loop Structures (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), DNA, Superhelical (mesh), R-Loop Structures (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), Kinetics (mesh), DNA (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/3x49q1fn
https://escholarship.org/content/qt3x49q1fn/qt3x49q1fn.pdf

Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors

Autoren: Patel, Deepak T Stogios, Peter J Jaroszewski, Lukasz et al.

Quelle: Molecular Systems Biology. 21(1)

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), Infectious Diseases (rcdc), Pneumonia (rcdc), Lung (rcdc), Pneumonia & Influenza (rcdc), Rare Diseases (rcdc), Infection (hrcs-hc), Legionella pneumophila (mesh), Bacterial Proteins (mesh), Protein Domains (mesh), Saccharomyces cerevisiae (mesh), Type IV Secretion Systems (mesh), Bacterial Effectors, Legionella pneumophila, Protein Modeling, Yeast Toxicity, Cryptic Domains, Legionella pneumophila (mesh), Saccharomyces cerevisiae (mesh), Bacterial Proteins (mesh), Type IV Secretion Systems (mesh), Protein Domains (mesh), Legionella pneumophila, Bacterial Effectors, Cryptic Domains, Protein Modeling, Yeast Toxicity, Legionella pneumophila (mesh), Bacterial Proteins (mesh), Protein Domains (mesh), Saccharomyces cerevisiae (mesh), Type IV Secretion Systems (mesh), 0601 Biochemistry and Cell Biology (for), 0699 Other Biological Sciences (for), Bioinformatics (science-metrix), 3101 Biochemistry and cell biology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/8jm007mj
https://escholarship.org/content/qt8jm007mj/qt8jm007mj.pdf

Efficient and multiplexed somatic genome editing with Cas12a mice

Autoren: Hebert, Jess D Xu, Haiqing Tang, Yuning J et al.

Quelle: Nature Biomedical Engineering. 9(11)

Schlagwörter: 40 Engineering (for-2020), 4003 Biomedical Engineering (for-2020), Biotechnology (rcdc), Human Genome (rcdc), Genetics (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Cancer (hrcs-hc), Animals (mesh), Mice, Transgenic (mesh), Mice (mesh), Acidaminococcus (mesh), Endodeoxyribonucleases (mesh), Bacterial Proteins (mesh), Genotype (mesh), Genome (mesh), CRISPR-Cas Systems (mesh), CRISPR-Associated Proteins (mesh), Gene Editing (mesh), RNA, Guide, CRISPR-Cas Systems (mesh), 4003 Biomedical engineering (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/7x83x8vx
https://escholarship.org/content/qt7x83x8vx/qt7x83x8vx.pdf