Search Results - "BIOINFORMATICS"

Rapid shifts in bryophyte phenology revealed by airborne eDNA

Authors: Bengtsson, Fia Cronberg, Nils Lozano Villegas, Jose Antonio et al.

Contributors: Bengtsson, Fia Cronberg, Nils Lozano Villegas, Jose Antonio et al.

Source: Journal of Ecology. 113(12):3564-3578

Subject Terms: Natural Sciences, Biological Sciences, Naturvetenskap, Biologi, Computer and Information Sciences, Bioinformatics (Computational Biology), Data- och informationsvetenskap (Datateknik), Bioinformatik (Beräkningsbiologi), Earth and Related Environmental Sciences, Climate Science, Geovetenskap och relaterad miljövetenskap, Klimatvetenskap

Access URL: https://doi.org/10.1111/1365-2745.70180

The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes

Authors: Odai, Roni Leemann, Michèle Al-Murad, Tamim et al.

Contributors: Odai, Roni Leemann, Michèle Al-Murad, Tamim et al.

Source: Science Advances. 11(40):1-14

Subject Terms: Natural Sciences, Biological Sciences, Bioinformatics and Computational Biology, Naturvetenskap, Biologi, Bioinformatik och beräkningsbiologi

Access URL: https://doi.org/10.1126/sciadv.adz8560

Genomic data reanalysis and variant reinterpretation in genetic diseases: A bioinformatic and clinical reevaluation in inherited cardiac conditions and suspected Fanconi anaemia patient cohorts

Authors: Tejero Laguna, Eudald

Thesis Advisors: Rodríguez Santiago, Benjamín, Surrallés i Calonge, Jordi

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Reanàlisi, Reanalysis, Reanálisis, Seqüenciació, Next generation sequencing, Secuenciación, Bionformàtica, Bioinformatics, Bioinformática, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695929

Bioinformatics characterization on the conformational transitions of intrinsically disordered proteins: functional and biomedical implications

Authors: Pintado Grima, Carlos

Thesis Advisors: Ventura Zamora, Salvador

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Bioinformàtica, Bioinformatics, Bioinformática, Proteïnes desordenades, Disordered proteins, Proteínas desordenadas, Agregació de proteïnes, Protein aggregation, Agregación de proteínas, Ciències Experimentals

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695583

Exploring the dynamics of the β2-adrenergic receptor: insights from explainable AI in GPCR research

Authors: Gutiérrez Mondragón, Mario Alberto

Contributors: University/Department: Universitat Politècnica de Catalunya. Departament de Ciències de la Computació

Thesis Advisors: Vellido Alcacena, Alfredo, König, Caroline

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: GPCRs, G protein-coupled receptors, beta2-adrenergic receptor, molecular dynamics, deep learning, machine learning, supervised learning, explainable artificial intelligence, convolutional neural networks, residue interaction networks, conformational states, model explanations, knowledge discovery, ANOVA, feature relevance, class imbalance, bioinformatics, structural bioinformatics, proteomics, pharmacology, Àrees temàtiques de la UPC::Informàtica, Àrees temàtiques de la UPC::Ciències de la salut, 004 - Informàtica, 577 - Bioquímica. Biologia molecular. Biofísica

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695469
https://dx.doi.org/10.5821/dissertation-2117-443474

From risk modification to precision therapy: integrated strategies for enhancing cancer prevention and treatment

Authors: Espin Garcia, Roderic

Thesis Advisors: Pujana Genestar, M. Ángel, Cáceres Aguilar, Mario

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Càncer bioinformàtica, Cancer bioinformatics, Cáncer bioinformática, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695305

Deciphering the mechanisms of skeletal muscle aging

Authors: Ramírez Pardo, Ignacio

Thesis Advisors: Muñoz Cánoves, Pura

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Múscul esquelètic, Skeletal Muscle, Músculo Esquelético, Envelliment, Aging, Envejecimiento, Autofàgia, Autophagy, Autofagia, Cèl·lules mare del múscul, Muscle Stem Cell, Células Madre de músculo, Bioinformàtica, Bioinformatics, Bioinformática

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695050

BINDSCAN: a computational protocol for the engineering of glycoside hydrolases

Authors: Vega Sánchez, Aitor

Contributors: University/Department: Universitat Ramon Llull. IQS

Thesis Advisors: Biarnés Fontal, Xavier, Planas Sauter, Antoni

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Protein Engineering, Biochemistry, Glycoside Hydrolase, Transglycosylation, Electrostatic Potential, Binding Affinity, Bioinformatics, Glycobiology, Molecular Modeling, Enzyme Design, Ciències naturals, químiques, físiques i matemàtiques

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694851

Unravelling Neural Heterogeneity in Mental Disorders: The Role of Genetics, Cognition, and Comorbidities

Authors: Fortea González, Lydia

Contributors: University/Department: Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut

Thesis Advisors: Vieta i Pascual, Eduard, 1963-, Radua, Joaquim

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Psiquiatria, Psiquiatría, Psychiatry, Imatges per ressonància magnètica, Imágenes por resonancia magnética, Magnetic resonance imaging, Bioinformàtica, Bioinformática, Bioinformatics, Trastorn bipolar, Trastornos bipolares, Manic-depressive illness, Trastorns per dèficit d'atenció amb hiperactivitat en els adults, Trastornos por déficit de atención con hiperactividad en adultos, Attention deficit disorder with hyperactivity in adults, Ciències de la Salut

Time: 616.89

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694690

Data of the Insect Biome Atlas: a metabarcoding survey of the terrestrial arthropods of Sweden and Madagascar

Authors: Miraldo, A Sundh, J Iwaszkiewicz-Eggebrecht, E et al.

Contributors: Miraldo, A Sundh, J Iwaszkiewicz-Eggebrecht, E et al.

Source: Scientific Data. 12:1-18

Subject Terms: Natural Sciences, Biological Sciences, Ecology (including Biodiversity Conservation), Naturvetenskap, Biologi, Ekologi, Bioinformatics and Computational Biology, Bioinformatik och beräkningsbiologi, Genetics and Genomics, Genetik och genomik

Access URL: https://doi.org/10.1038/s41597-025-05151-0

Happ: High-accuracy pipeline for processing deep metabarcoding data

Authors: Sundh, John Granqvist, Emma Iwaszkiewicz-Eggebrecht, Ela et al.

Contributors: Sundh, John Granqvist, Emma Iwaszkiewicz-Eggebrecht, Ela et al.

Source: PLoS Computational Biology. 21(11)

Subject Terms: Natural Sciences, Biological Sciences, Bioinformatics and Computational Biology, Naturvetenskap, Biologi, Bioinformatik och beräkningsbiologi

Access URL: https://doi.org/10.1371/journal.pcbi.1013558

Data integration of longitudinal single-cell with multi-omics data to enable precision medicine for complex diseases

Authors: Mihajlović, Katarina

Contributors: University/Department: Universitat Politècnica de Catalunya. Departament de Ciències de la Computació

Thesis Advisors: Przulj, Natasa, Larrosa Bondia, Francisco Javier

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: bioinformatics, network biology, multi-omics, data integration, single-cell, precision medicine, machine learning, complex diseases, Àrees temàtiques de la UPC::Informàtica, Àrees temàtiques de la UPC::Enginyeria biomèdica, 004 - Informàtica, 616 - Patologia. Medicina clínica. Oncologia

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694728
https://dx.doi.org/10.5821/dissertation-2117-432840

Development of vectorial descriptors to characterize small molecules and protein druggable pockets

Authors: Comajuncosa Creus, Arnau

Thesis Advisors: Aloy, Patrick, 1972-, Barril Alonso, Xavier, Marechal , Jean Didier Pierre

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Quimioinformàtica, Cheminformatics, Quimioinformática, Disseny de fàrmacs, Drug Design, Diseño de fármacos, Bioinformàtica, Bioinformatics, Bioinformática, Ciències Experimentals

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694100

Evolutionary dynamics of cancer drug resistance and prediction of tumor modes of growth

Authors: Dick, Nicola Elisabeth

Contributors: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

Thesis Advisors: Weghorn, Donate

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Population genetics, Cancer, Evolution, Bioinformatics, Selection, Genética de poblaciones, Cáncer, Evolución, Bioinformática, Selección

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/693720

The cerebellum converts input data into a hyper low-resolution granule cell code with spatial dimensions: A hypothesis

Authors: Gilbert, Mike Rasmussen, Anders Lund University, Faculty of Medicine, Department of Experimental Medical Science, Associative Learning, Lunds universitet, Medicinska fakulteten, Institutionen för experimentell medicinsk vetenskap, Associativ inlärning, Originator

Contributors: Gilbert, Mike Rasmussen, Anders Lund University, Faculty of Medicine, Department of Experimental Medical Science, Associative Learning, Lunds universitet, Medicinska fakulteten, Institutionen för experimentell medicinsk vetenskap, Associativ inlärning, Originator

Source: Royal Society Open Science. 12(3):1-28

Subject Terms: Natural Sciences, Biological Sciences, Bioinformatics and Computational Biology, Naturvetenskap, Biologi, Bioinformatik och beräkningsbiologi

Access URL: https://doi.org/10.1098/rsos.241665

XeroGraph: enhancing data integrity in the presence of missing values with statistical and predictive analysis

Authors: Mousafi Alasal, Laila Hammarlund, Emma U Pienta, Kenneth J et al.

Contributors: Mousafi Alasal, Laila Hammarlund, Emma U Pienta, Kenneth J et al.

Source: Bioinformatics Advances. 5(1):1-6

Subject Terms: Natural Sciences, Biological Sciences, Bioinformatics and Computational Biology, Naturvetenskap, Biologi, Bioinformatik och beräkningsbiologi

Access URL: https://doi.org/10.1093/bioadv/vbaf035

Epitope Mapping with Sidewinder: An XL-MS and Structural Modeling Approach

Authors: Ströbaek, Joel Tang, Di Gueto-Tettay, Carlos et al.

Contributors: Ströbaek, Joel Tang, Di Gueto-Tettay, Carlos et al.

Source: International Journal of Molecular Sciences. 26(4):1-17

Subject Terms: Natural Sciences, Computer and Information Sciences, Bioinformatics (Computational Biology), Naturvetenskap, Data- och informationsvetenskap (Datateknik), Bioinformatik (Beräkningsbiologi)

Access URL: https://doi.org/10.3390/ijms26041488

Widespread false negatives in DNA-encoded library data: how linker effects impair machine learning-based lead prediction

Authors: Montoya, Alba L. Hogendorf, Adam S. Tingey, Steven et al.

Contributors: Montoya, Alba L. Hogendorf, Adam S. Tingey, Steven et al.

Source: Chemical Science. 16(24):10918-10927

Subject Terms: Natural Sciences, Biological Sciences, Bioinformatics and Computational Biology, Naturvetenskap, Biologi, Bioinformatik och beräkningsbiologi

Access URL: https://doi.org/10.1039/d5sc00844a

Antisense-mediated regulation of exon usage in the elastic spring region of Titin modulates sarcomere function

Authors: Celik, Selvi Hyrefelt, Ludvig Czuba, Tomasz et al.

Source: Cardiovascular Research. 121(4):629-642

Subject Terms: Bioinformatik, Bioinformatics

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-24944
https://doi.org/10.1093/cvr/cvaf037

Visualization for Diagnostic Review of Copy Number Variants in Complex DNA Sequencing Data

Authors: Ståhlbom, Emilia Molin, Jesper Lundström, Claes et al.

Source: IEEE Transactions on Visualization and Computer Graphics. 31(4):2211-2222

Subject Terms: Bioinformatics, Genomics, Data visualization, Sequential analysis, DNA, Task analysis, Reviews, Visualization, genomics, copy number variants, clinical decision support, evaluation

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-212297
https://doi.org/10.1109/TVCG.2024.3385118