Suchergebnisse - "Autophagy"

Identification of ATG7 as a protein ATG8ylation substrate.

Autoren: Xie H Long J Huang Y et al.

Quelle: Cell reports [Cell Rep] 2025 Nov 25; Vol. 44 (11), pp. 116485. Date of Electronic Publication: 2025 Nov 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Autophagy-Related Protein 7*/metabolism , Autophagy-Related Protein 7*/genetics , Autophagy-Related Protein 8 Family*/metabolism, Autophagy-Related Proteins/metabolism ; Humans ; Autophagy ; Microtubule-Associated Proteins/metabolism ; Protein Processing, Post-Translational ; Ubiquitin-Conjugating Enzymes/metabolism ; Substrate Specificity ; HEK293 Cells

Phase separation promotes Atg8 lipidation and vesicle condensation for autophagy progression.

Autoren: Fujioka Y Tsuji T Kotani T et al.

Quelle: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Nov; Vol. 32 (11), pp. 2285-2295. Date of Electronic Publication: 2025 Sep 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/physiology , Saccharomyces cerevisiae Proteins*/metabolism , Autophagy-Related Protein 8 Family*/metabolism , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/cytology , Autophagosomes*/metabolism, Autophagy-Related Proteins/metabolism ; Autophagy-Related Protein 12/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Autophagy-Related Protein 5/metabolism ; Microtubule-Associated Proteins/metabolism ; Phase Separation ; Protein Kinases

Autophagy regulates MK-2206-induced LDL receptor expression and cholesterol efflux pathways.

Autoren: Sundvold H Strøm TB

Quelle: PloS one [PLoS One] 2025 Dec 04; Vol. 20 (12), pp. e0338076. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/drug effects , Autophagy*/genetics , Receptors, LDL*/metabolism , Receptors, LDL*/genetics , Cholesterol*/metabolism , Heterocyclic Compounds, 3-Ring*/pharmacology, Humans ; Hep G2 Cells ; ATP Binding Cassette Transporter 1/metabolism ; ATP Binding Cassette Transporter 1/genetics ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 7/genetics ; Hepatocytes/metabolism ; Hepatocytes/drug effects ; Sterol Regulatory Element Binding Protein 2/metabolism ; Sterol Regulatory Element Binding Protein 2/genetics ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/metabolism

Mechanism of autophagy initiation by transmembrane selective autophagy receptors.

Autoren: Adriaenssens E Martens S

Quelle: The EMBO journal [EMBO J] 2025 Dec; Vol. 44 (23), pp. 6786-6796. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/physiology , Autophagy-Related Proteins*/metabolism, Humans ; Animals ; Autophagy-Related Protein-1 Homolog/metabolism

Autophagy-mediated bioactive glass 1393 promotes wound healing and improves healing quality.

Autoren: Zhang F Yan H Zhang L et al.

Quelle: Burns : journal of the International Society for Burn Injuries [Burns] 2025 Dec; Vol. 51 (9), pp. 107708. Date of Electronic Publication: 2025 Sep 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8913178 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1409 (Electronic) Linking ISSN: 03054179 NLM ISO Abbreviation: Burns Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/drug effects , Wound Healing*/drug effects , Glass* , Biocompatible Materials*/pharmacology, Humans ; Animals ; HaCaT Cells ; Microscopy, Electron, Transmission ; TOR Serine-Threonine Kinases/metabolism ; TOR Serine-Threonine Kinases/drug effects ; Autophagy-Related Protein 7/genetics ; Autophagy-Related Protein-1 Homolog/metabolism ; Autophagy-Related Protein-1 Homolog/drug effects ; Autophagy-Related Protein 5/genetics

Teleost HMGB1 paralogues mediate protective autophagy by interacting with NOD2 and ATG16L1 and activating ROS/Akt/mTOR pathway against Aeromonas hydrophila infection.

Autoren: Wang D Chen L Ma X et al.

Quelle: Fish & shellfish immunology [Fish Shellfish Immunol] 2025 Dec; Vol. 167, pp. 110902. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 9505220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9947 (Electronic) Linking ISSN: 10504648 NLM ISO Abbreviation: Fish Shellfish Immunol Subsets: MEDLINE

MeSH-Schlagworte: Fish Diseases*/immunology , HMGB1 Protein*/genetics , HMGB1 Protein*/immunology , Autophagy*/immunology , Autophagy*/genetics , Carps*/immunology , Immunity, Innate*/genetics, Animals ; Aeromonas hydrophila/physiology ; Gram-Negative Bacterial Infections/immunology ; Gram-Negative Bacterial Infections/veterinary ; Fish Proteins/genetics ; Fish Proteins/immunology ; Signal Transduction ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/immunology ; TOR Serine-Threonine Kinases/genetics ; Nod2 Signaling Adaptor Protein/genetics ; Nod2 Signaling Adaptor Protein/immunology ; Reactive Oxygen Species/metabolism

Reticulophagy receptor FAM134C restrains BMP receptor signaling.

Autoren: Gu S Zhang H Cao J et al.

Quelle: The EMBO journal [EMBO J] 2025 Dec; Vol. 44 (23), pp. 7154-7180. Date of Electronic Publication: 2025 Oct 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

MeSH-Schlagworte: Signal Transduction* , Autophagy* , Bone Morphogenetic Protein Receptors, Type I*/metabolism , Bone Morphogenetic Protein Receptors, Type I*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Intracellular Signaling Peptides and Proteins*/metabolism , Intracellular Signaling Peptides and Proteins*/genetics, Animals ; Mice ; Humans ; Mice, Knockout ; Microtubule-Associated Proteins/metabolism ; Microtubule-Associated Proteins/genetics ; HEK293 Cells ; Beclin-1/metabolism ; Autophagy-Related Protein 5/metabolism ; Proteolysis ; Endoplasmic Reticulum/metabolism ; Autophagy-Related Proteins

The peptide ENSG00000232259-ORF inhibits glioma cell proliferation and migration by promoting autophagy.

Autoren: Zhang J Wei G Du B et al.

Quelle: Brain research [Brain Res] 2025 Nov 01; Vol. 1866, pp. 149942. Date of Electronic Publication: 2025 Sep 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/physiology , Autophagy*/genetics , Glioma*/metabolism , Glioma*/genetics , Glioma*/pathology , Cell Movement*/physiology , Cell Movement*/genetics , Cell Movement*/drug effects , Brain Neoplasms*/metabolism , Brain Neoplasms*/genetics , Brain Neoplasms*/pathology , RNA, Long Noncoding*/metabolism , RNA, Long Noncoding*/genetics , Peptides*/metabolism , Peptides*/genetics, Cell Proliferation/physiology ; Cell Proliferation/genetics ; Cell Proliferation/drug effects ; Humans ; Cell Line, Tumor ; Autophagy-Related Proteins/metabolism ; Autophagy-Related Proteins/genetics ; Gene Expression Regulation, Neoplastic ; Ubiquitin-Conjugating Enzymes

Role of autophagy‑modulating long non‑coding RNAs in tumor radioresistance (Review).

Autoren: Li H He Z

Quelle: Oncology reports [Oncol Rep] 2025 Nov; Vol. 54 (5). Date of Electronic Publication: 2025 Aug 24.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9422756 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-2431 (Electronic) Linking ISSN: 1021335X NLM ISO Abbreviation: Oncol Rep Subsets: MEDLINE

MeSH-Schlagworte: RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism , Autophagy*/genetics , Autophagy*/radiation effects , Radiation Tolerance*/genetics , Neoplasms*/genetics , Neoplasms*/radiotherapy , Neoplasms*/pathology, Humans ; Gene Expression Regulation, Neoplastic/radiation effects ; Signal Transduction/genetics ; Animals ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism

Single-cell transcriptome analysis highlights a critical role of ATG5 for endothelial cells in diabetic nephropathy.

Autoren: Zhang Y Che L Gao H et al.

Quelle: Human cell [Hum Cell] 2025 Oct 08; Vol. 38 (6), pp. 174. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Japan NLM ID: 8912329 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-0774 (Electronic) Linking ISSN: 09147470 NLM ISO Abbreviation: Hum Cell Subsets: MEDLINE

MeSH-Schlagworte: Diabetic Nephropathies*/genetics , Diabetic Nephropathies*/pathology , Autophagy-Related Protein 5*/genetics , Autophagy-Related Protein 5*/physiology , Autophagy-Related Protein 5*/metabolism , Endothelial Cells*/pathology , Endothelial Cells*/metabolism , Single-Cell Analysis*/methods , Gene Expression Profiling*, Humans ; Animals ; Autophagy/genetics ; Sirtuin 1/metabolism ; Sirtuin 1/genetics ; Sirtuin 1/physiology ; Apoptosis/genetics ; Mice ; Disease Models, Animal ; Glucose ; Cells, Cultured ; Kidney Glomerulus/pathology ; Kidney Glomerulus/cytology ; Epithelial-Mesenchymal Transition/genetics ; Single-Cell Gene Expression Analysis

Development of a p62 biodegrader for autophagy targeted degradation.

Autoren: Thiel Z Marcellin D Manneville C et al.

Quelle: Nature communications [Nat Commun] 2025 Dec 03; Vol. 16 (1), pp. 10858. Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Autophagy* , Sequestosome-1 Protein*/metabolism , Sequestosome-1 Protein*/genetics, Humans ; Proteolysis ; Mitochondria/metabolism ; Autophagy-Related Protein-1 Homolog/metabolism ; Autophagy-Related Protein-1 Homolog/genetics ; Lysosomes/metabolism ; Protein Serine-Threonine Kinases/metabolism ; Protein Serine-Threonine Kinases/genetics ; HeLa Cells ; Mitophagy ; Intracellular Signaling Peptides and Proteins/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; HEK293 Cells ; Autophagy-Related Protein 8 Family/metabolism ; Animals

Association of autophagy-related proteins in serum and synovial fluid with the severity of knee osteoarthritis.

Autoren: Okuyan HM Dogan S Erdoğan HF et al.

Quelle: The Knee [Knee] 2025 Dec; Vol. 57, pp. 37-46. Date of Electronic Publication: 2025 Aug 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9430798 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5800 (Electronic) Linking ISSN: 09680160 NLM ISO Abbreviation: Knee Subsets: MEDLINE

MeSH-Schlagworte: Osteoarthritis, Knee*/metabolism , Osteoarthritis, Knee*/diagnostic imaging , Osteoarthritis, Knee*/blood , Synovial Fluid*/metabolism , Autophagy-Related Proteins*/metabolism , Autophagy-Related Proteins*/blood, Humans ; Male ; Female ; Middle Aged ; Severity of Illness Index ; Aged ; Biomarkers/metabolism ; Biomarkers/blood ; Autophagy ; Beclin-1/metabolism ; Beclin-1/blood

Dietary urolithin A suppresses lung cancer via gut microbiota-mediated autophagy activation.

Autoren: Zhang J Li X Sun L et al.

Quelle: The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Dec; Vol. 146, pp. 110080. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

MeSH-Schlagworte: Coumarins*/administration & dosage , Coumarins*/pharmacology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Gastrointestinal Microbiome*/drug effects , Autophagy*/drug effects , Autophagy*/genetics, Diet ; Cell Proliferation/drug effects ; Xenograft Model Antitumor Assays ; Humans ; Male ; Mice, Inbred BALB C ; Mice, Nude ; A549 Cells ; Lactobacillus/drug effects ; Lactobacillus/growth & development ; Desulfovibrio/drug effects ; Animals ; Mice ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; MAP Kinase Signaling System/drug effects ; Autophagy-Related Proteins/genetics ; Gene Expression/drug effects

PIF4 controls autophagy during hypocotyl response to elevated ambient temperatures via ArpC5 in Arabidopsis.

Autoren: Pan Q Luo L Li J

Quelle: Developmental cell [Dev Cell] 2025 Dec 01; Vol. 60 (23), pp. 3236-3249.e4. Date of Electronic Publication: 2025 Jul 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

MeSH-Schlagworte: Arabidopsis*/metabolism , Arabidopsis*/genetics , Arabidopsis*/growth & development , Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Autophagy*/physiology , Hypocotyl*/metabolism , Hypocotyl*/growth & development , Basic Helix-Loop-Helix Transcription Factors*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/genetics , Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/genetics, Gene Expression Regulation, Plant ; Autophagy-Related Protein 8 Family/metabolism ; Autophagy-Related Protein 8 Family/genetics ; Actin Cytoskeleton/metabolism ; Actins/metabolism ; Indoleacetic Acids/metabolism ; Autophagosomes/metabolism

Peptide AEDL Activates Metabolism and Autophagy in Root Cells of Nicotiana tabacum .

Autoren: Lazareva EM Kazakov EP Dilovarova TA et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 14; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Nicotiana*/metabolism , Nicotiana*/drug effects , Nicotiana*/ultrastructure , Nicotiana*/growth & development , Nicotiana*/genetics , Autophagy*/drug effects , Plant Roots*/metabolism , Plant Roots*/drug effects , Plant Roots*/cytology , Plant Roots*/ultrastructure , Peptides*/pharmacology, Plant Proteins/metabolism ; Plant Proteins/genetics ; Gene Expression Regulation, Plant/drug effects ; Autophagy-Related Protein 8 Family/metabolism ; Autophagy-Related Protein 8 Family/genetics

Inhibition of Histone Methyltransferase G9a Activates Autophagy and Provides Protection in Dry Eye Disease.

Autoren: Chen Z Tang Y Jiang J et al.

Quelle: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Nov 03; Vol. 66 (14), pp. 52.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

MeSH-Schlagworte: Histone-Lysine N-Methyltransferase*/antagonists & inhibitors , Histone-Lysine N-Methyltransferase*/metabolism , Histocompatibility Antigens*/metabolism , Autophagy*/drug effects , Autophagy*/genetics , Dry Eye Syndromes*/chemically induced , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/pathology , Epithelium, Corneal*/cytology , Epithelium, Corneal*/drug effects , Epithelium, Corneal*/pathology, Disease Models, Animal ; Cell Line ; Benzalkonium Compounds/administration & dosage ; Benzalkonium Compounds/toxicity ; Severity of Illness Index ; Oxidative Stress/drug effects ; Apoptosis/drug effects ; Humans ; Animals ; Mice ; Autophagy-Related Protein 7/genetics ; Autophagy-Related Protein 7/metabolism ; Histones/metabolism ; Gene Silencing/drug effects ; Female ; Down-Regulation/drug effects

ATG9A and ARFIP2 cooperate to control PI4P levels for lysosomal repair.

Autoren: De Tito S Almacellas E Dai Yu D et al.

Quelle: Developmental cell [Dev Cell] 2025 Oct 20; Vol. 60 (20), pp. 2744-2760.e9. Date of Electronic Publication: 2025 Jun 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

MeSH-Schlagworte: Lysosomes*/metabolism , Autophagy-Related Proteins*/metabolism , Autophagy-Related Proteins*/genetics , Phosphatidylinositol Phosphates*/metabolism , Vesicular Transport Proteins*/metabolism , Vesicular Transport Proteins*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics, Humans ; Animals ; Mice ; Endoplasmic Reticulum/metabolism ; HeLa Cells ; Autophagy ; Endosomes/metabolism

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion.

Autoren: Kumari R Nath T Pflaum J et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Oct 14; Vol. 122 (41), pp. e2426476122. Date of Electronic Publication: 2025 Oct 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/physiology , Autophagosomes*/metabolism , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/genetics , Vesicular Transport Proteins*/metabolism , Vesicular Transport Proteins*/genetics, Autophagy-Related Proteins/metabolism ; Autophagy-Related Proteins/genetics ; Mutation

Characterization of Corneal Defects in ATG7-Deficient Mice.

Autoren: Volatier T Mourier A Mann J et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 14; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Autophagy-Related Protein 7*/genetics , Autophagy-Related Protein 7*/deficiency , Autophagy-Related Protein 7*/metabolism , Cornea*/metabolism , Cornea*/pathology , Epithelium, Corneal*/metabolism , Epithelium, Corneal*/pathology , Corneal Diseases*/metabolism , Corneal Diseases*/pathology , Corneal Diseases*/genetics, Animals ; Mice ; Autophagy/genetics ; Mice, Knockout ; Lymphangiogenesis ; Autophagosomes/metabolism ; Proteomics ; Disease Models, Animal

Molecular bases of the interactions of ATG16L1 with FIP200 and ATG8 family proteins.

Autoren: Gong X Zhou Y Wang Y et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 10; Vol. 16 (1), pp. 9035. Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Autophagy-Related Proteins*/metabolism , Autophagy-Related Proteins*/chemistry , Autophagy-Related Proteins*/genetics , Autophagy-Related Protein 8 Family*/metabolism , Autophagy-Related Protein 8 Family*/genetics , Autophagy-Related Protein 8 Family*/chemistry , Carrier Proteins*/metabolism , Carrier Proteins*/genetics , Carrier Proteins*/chemistry, Humans ; Protein Binding ; Autophagy ; Adaptor Proteins, Signal Transducing/metabolism ; Adaptor Proteins, Signal Transducing/chemistry ; Adaptor Proteins, Signal Transducing/genetics ; Microtubule-Associated Proteins/metabolism ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/chemistry ; Crystallography, X-Ray ; HEK293 Cells ; Autophagosomes/metabolism ; Models, Molecular ; Animals