Search Results - "Atorvastatin"

Study on the protective effects and mechanisms of atorvastatin in retinal ischemia-reperfusion injury in mice.

Authors: Yin K Li X Chen H et al.

Source: Experimental eye research [Exp Eye Res] 2025 Dec; Vol. 261, pp. 110686. Date of Electronic Publication: 2025 Oct 09.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 0370707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0007 (Electronic) Linking ISSN: 00144835 NLM ISO Abbreviation: Exp Eye Res Subsets: MEDLINE

MeSH Terms: Reperfusion Injury*/metabolism , Reperfusion Injury*/prevention & control , Reperfusion Injury*/drug therapy , Reperfusion Injury*/pathology , Atorvastatin*/therapeutic use , Atorvastatin*/pharmacology , Retinal Diseases*/prevention & control , Retinal Diseases*/metabolism , Retinal Diseases*/pathology , Retinal Diseases*/drug therapy , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use, Animals ; Mice ; Retinal Ganglion Cells/pathology ; Retinal Ganglion Cells/drug effects ; Retinal Ganglion Cells/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; Insulin-Like Growth Factor I/genetics ; Insulin-Like Growth Factor I/metabolism ; Male ; Blotting, Western ; Retinal Vessels/pathology ; Cell Survival ; Electroretinography

Mapping the polar metabolome in Huh-7 liver cancer cells reveal the role of atorvastatin in enhancing chemotherapeutic efficacy of doxorubicin.

Authors: Kopsida M Regtop L Lennernäs H et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Nov 15; Vol. 265, pp. 117012. Date of Electronic Publication: 2025 Jun 06.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH Terms: Atorvastatin*/pharmacology , Atorvastatin*/administration & dosage , Doxorubicin*/pharmacology , Doxorubicin*/administration & dosage , Liver Neoplasms*/drug therapy , Liver Neoplasms*/metabolism , Metabolome*/drug effects , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/metabolism , Antineoplastic Combined Chemotherapy Protocols*/pharmacology, Humans ; Cell Line, Tumor ; Drug Synergism ; Oxidative Stress/drug effects ; Lipid Metabolism/drug effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Inhibitory Concentration 50 ; Metabolomics/methods ; Dose-Response Relationship, Drug

Efficacy and Safety of Fimasartan, Atorvastatin, and Ezetimibe Combination Therapy in Patients With Hypertension and Dyslipidemia: A Randomized, Double-Blind, Multicenter, Therapeutic Confirmatory, Phase III Clinical Trial.

Authors: Hong SJ Kim JH Cha KS et al.

Source: Clinical therapeutics [Clin Ther] 2025 Nov; Vol. 47 (11), pp. 1028-1036. Date of Electronic Publication: 2025 Sep 14.

Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III

Journal Info: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE

MeSH Terms: Hypertension*/drug therapy , Hypertension*/complications , Pyrimidines*/adverse effects , Pyrimidines*/therapeutic use , Pyrimidines*/administration & dosage , Atorvastatin*/adverse effects , Atorvastatin*/therapeutic use , Atorvastatin*/administration & dosage , Biphenyl Compounds*/adverse effects , Biphenyl Compounds*/therapeutic use , Biphenyl Compounds*/administration & dosage , Anticholesteremic Agents*/therapeutic use , Anticholesteremic Agents*/adverse effects , Anticholesteremic Agents*/administration & dosage , Tetrazoles*/adverse effects , Tetrazoles*/therapeutic use , Tetrazoles*/administration & dosage , Hypercholesterolemia*/drug therapy , Hypercholesterolemia*/complications , Dyslipidemias*/drug therapy , Dyslipidemias*/complications , Azetidines*/adverse effects , Azetidines*/therapeutic use , Azetidines*/administration & dosage , Antihypertensive Agents*/therapeutic use , Antihypertensive Agents*/adverse effects , Antihypertensive Agents*/administration & dosage, Humans ; Male ; Female ; Middle Aged ; Drug Therapy, Combination ; Double-Blind Method ; Ezetimibe/adverse effects ; Ezetimibe/therapeutic use ; Aged ; Republic of Korea ; Blood Pressure/drug effects ; Treatment Outcome ; Cholesterol, LDL/blood

Atorvastatin alleviates atherosclerosis by improving intestinal barrier function in mice and patients by modulating inflammation.

Authors: Yin C Li L Zhang Z et al.

Source: International immunopharmacology [Int Immunopharmacol] 2025 Oct 10; Vol. 163, pp. 115202. Date of Electronic Publication: 2025 Jul 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: Atorvastatin*/therapeutic use , Atorvastatin*/pharmacology , Atherosclerosis*/drug therapy , Intestinal Mucosa*/drug effects , Intestinal Mucosa*/metabolism , Anti-Inflammatory Agents*/therapeutic use , Anti-Inflammatory Agents*/pharmacology, Animals ; Humans ; Male ; Caco-2 Cells ; Mice ; Female ; Mice, Inbred C57BL ; Inflammation/drug therapy ; Middle Aged ; Disease Models, Animal ; Mice, Knockout, ApoE ; Apolipoproteins E/genetics ; Intestinal Barrier Function

Comparative Study Between the Effects of High Doses of Rosuvastatin and Atorvastatin on Ventricular Remodeling in Patients with ST-Segment Elevation Myocardial Infarction.

Authors: Elhadad ZM Kassem AB Amrawy AME et al.

Source: Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2025 Oct; Vol. 39 (5), pp. 1113-1123. Date of Electronic Publication: 2024 Sep 12.

Publication Type: Journal Article; Randomized Controlled Trial; Comparative Study

Journal Info: Publisher: Kluwer Academic For The International Society For Cardiovascular Pharmacotherapy Country of Publication: United States NLM ID: 8712220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7241 (Electronic) Linking ISSN: 09203206 NLM ISO Abbreviation: Cardiovasc Drugs Ther Subsets: MEDLINE

MeSH Terms: Rosuvastatin Calcium*/administration & dosage , Rosuvastatin Calcium*/adverse effects , Atorvastatin*/administration & dosage , Atorvastatin*/adverse effects , Ventricular Remodeling*/drug effects , ST Elevation Myocardial Infarction*/therapy , ST Elevation Myocardial Infarction*/physiopathology , ST Elevation Myocardial Infarction*/diagnostic imaging , ST Elevation Myocardial Infarction*/blood , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects , Percutaneous Coronary Intervention*/adverse effects , Ventricular Function, Left*/drug effects, Humans ; Male ; Female ; Middle Aged ; Aged ; Treatment Outcome ; Biomarkers/blood ; Inflammation Mediators/blood ; Time Factors ; C-Reactive Protein/metabolism ; Fibrosis ; Matrix Metalloproteinase 9

Effect of LDL-Cholesterol Levels and Oral Atorvastatin on Outcomes After Pipeline Therapy for Intracranial Aneurysms.

Authors: Feng X Huang C Tong X et al.

Source: Stroke [Stroke] 2025 Oct; Vol. 56 (10), pp. 3002-3013. Date of Electronic Publication: 2025 Aug 06.

Publication Type: Journal Article; Multicenter Study

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE

MeSH Terms: Atorvastatin*/administration & dosage , Atorvastatin*/therapeutic use , Intracranial Aneurysm*/blood , Intracranial Aneurysm*/therapy , Cholesterol, LDL*/blood , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Embolization, Therapeutic*/methods, Humans ; Female ; Male ; Middle Aged ; Treatment Outcome ; Aged ; Registries ; Adult ; Stents ; Administration, Oral

Comparative Effectiveness and Safety of Moderate-Intensity Pravastatin Versus Atorvastatin in Patients with Dyslipidemia: A Retrospective Cohort Study Using a Common Data Model of Multicenter Electronic Health Records in South Korea.

Authors: Chun SW Kim HJ Seo JA et al.

Source: Journal of atherosclerosis and thrombosis [J Atheroscler Thromb] 2025 Oct 01; Vol. 32 (10), pp. 1268-1303. Date of Electronic Publication: 2025 May 09.

Publication Type: Journal Article; Multicenter Study; Comparative Study

Journal Info: Publisher: Japan Atherosclerosis Society Country of Publication: Japan NLM ID: 9506298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-3873 (Electronic) Linking ISSN: 13403478 NLM ISO Abbreviation: J Atheroscler Thromb Subsets: MEDLINE

MeSH Terms: Pravastatin*/therapeutic use , Pravastatin*/adverse effects , Pravastatin*/administration & dosage , Atorvastatin*/therapeutic use , Atorvastatin*/adverse effects , Atorvastatin*/administration & dosage , Dyslipidemias*/drug therapy , Electronic Health Records*/statistics & numerical data, Humans ; Retrospective Studies ; Female ; Male ; Republic of Korea/epidemiology ; Middle Aged ; Aged ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Rhabdomyolysis ; Cardiovascular Diseases/prevention & control ; Prognosis ; Follow-Up Studies

Contact lenses eluting atorvastatin-loaded ginger-exosomes: mechanistic modulation of oxidative and inflammatory pathways in glaucoma management.

Authors: Bebawy G Ashour AA El-Moslemany RM et al.

Source: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126292. Date of Electronic Publication: 2025 Oct 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

MeSH Terms: Glaucoma*/drug therapy , Glaucoma*/metabolism , Atorvastatin*/administration & dosage , Atorvastatin*/pharmacokinetics , Atorvastatin*/chemistry , Atorvastatin*/pharmacology , Zingiber officinale*/chemistry , Contact Lenses*, Animals ; Rabbits ; Humans ; Drug Liberation ; Delayed-Action Preparations ; Oxidative Stress/drug effects ; Cell Survival/drug effects ; Male ; Intraocular Pressure/drug effects

Impact of High-Intensity Statin on Atrial Fibrillation after Off-Pump Coronary Artery Bypass.

Authors: Lee Y Kang Y Kim JS et al.

Source: The Thoracic and cardiovascular surgeon [Thorac Cardiovasc Surg] 2025 Dec; Vol. 73 (8), pp. 633-638. Date of Electronic Publication: 2024 Oct 24.

Publication Type: Journal Article

Journal Info: Publisher: Thieme Country of Publication: Germany NLM ID: 7903387 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-1902 (Electronic) Linking ISSN: 01716425 NLM ISO Abbreviation: Thorac Cardiovasc Surg Subsets: MEDLINE

MeSH Terms: Atrial Fibrillation*/prevention & control , Atrial Fibrillation*/diagnosis , Atrial Fibrillation*/etiology , Atrial Fibrillation*/epidemiology , Atrial Fibrillation*/physiopathology , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects , Coronary Artery Bypass, Off-Pump*/adverse effects , Coronary Artery Disease*/surgery , Coronary Artery Disease*/diagnosis , Atorvastatin*/administration & dosage , Atorvastatin*/adverse effects , Rosuvastatin Calcium*/administration & dosage , Rosuvastatin Calcium*/adverse effects, Humans ; Male ; Female ; Retrospective Studies ; Aged ; Risk Factors ; Middle Aged ; Treatment Outcome ; Time Factors ; Odds Ratio ; Logistic Models ; Multivariate Analysis ; Chi-Square Distribution

STAREE-HEART: A randomized placebo-controlled trial of atorvastatin effects on a marker of cardiac aging in older individuals without prior cardiovascular disease events: Protocol and baseline description of participants.

Authors: Hopper I Marwick TH Wolfe R et al.

Source: American heart journal [Am Heart J] 2025 Dec; Vol. 290, pp. 140-152. Date of Electronic Publication: 2025 Jun 12.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE

MeSH Terms: Atorvastatin*/therapeutic use , Atorvastatin*/administration & dosage , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Aging*/physiology , Aging*/drug effects , Ventricular Function, Left*/drug effects , Ventricular Function, Left*/physiology , Heart Failure*/prevention & control, Humans ; Aged ; Male ; Female ; Double-Blind Method ; Biomarkers/blood ; Echocardiography ; Electrocardiography ; Aged, 80 and over ; Primary Prevention/methods

Atorvastatin negatively regulates MAPK pathway in vitro to inhibit proliferation, migration, and invasion of hepatocellular carcinoma cells.

Authors: Meng Y Mo L Liang T et al.

Source: Scientific reports [Sci Rep] 2025 Nov 21; Vol. 15 (1), pp. 41279. Date of Electronic Publication: 2025 Nov 21.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Atorvastatin*/pharmacology , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/metabolism , Liver Neoplasms*/pathology , Liver Neoplasms*/drug therapy , Liver Neoplasms*/metabolism , Cell Proliferation*/drug effects , Cell Movement*/drug effects , MAP Kinase Signaling System*/drug effects, Humans ; Animals ; Mice ; Cell Line, Tumor ; Male ; Neoplasm Invasiveness ; Female ; Prognosis

Smart Antifungal Therapy: Lipase-Responsive Ketoconazole and Atorvastatin Co-loaded Poly є-caprolactone Nanoparticles for Cutaneous Candidiasis.

Authors: Gul P Ur Rehman A Ullah N et al.

Source: AAPS PharmSciTech [AAPS PharmSciTech] 2025 Nov 14; Vol. 27 (1), pp. 33. Date of Electronic Publication: 2025 Nov 14.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100960111 Publication Model: Electronic Cited Medium: Internet ISSN: 1530-9932 (Electronic) Linking ISSN: 15309932 NLM ISO Abbreviation: AAPS PharmSciTech Subsets: MEDLINE

MeSH Terms: Antifungal Agents*/administration & dosage , Antifungal Agents*/chemistry , Antifungal Agents*/pharmacology , Lipase*/metabolism , Lipase*/chemistry , Ketoconazole*/administration & dosage , Ketoconazole*/chemistry , Ketoconazole*/pharmacology , Nanoparticles*/chemistry , Atorvastatin*/administration & dosage , Atorvastatin*/chemistry , Atorvastatin*/pharmacology , Polyesters*/chemistry , Candidiasis, Cutaneous*/drug therapy, Animals ; Particle Size ; Drug Liberation ; Candida albicans/drug effects ; Mice ; Skin Absorption ; Skin/metabolism ; Drug Carriers/chemistry ; Administration, Cutaneous

The combined effect of statin and vitamin C in patients with pulmonary septic shock: a single-center, double-blind clinical trial.

Authors: Farzanegan B Shafigh N Hasheminik M et al.

Source: BMC infectious diseases [BMC Infect Dis] 2025 Oct 24; Vol. 25 (1), pp. 1407. Date of Electronic Publication: 2025 Oct 24.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE

MeSH Terms: Shock, Septic*/drug therapy , Shock, Septic*/mortality , Ascorbic Acid*/therapeutic use , Ascorbic Acid*/administration & dosage , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Atorvastatin*/therapeutic use , Atorvastatin*/administration & dosage, Humans ; Male ; Double-Blind Method ; Female ; Middle Aged ; Aged ; Intensive Care Units ; Drug Therapy, Combination ; Treatment Outcome ; C-Reactive Protein/analysis ; Adult ; Organ Dysfunction Scores

Effects of dengue virus type-2 serotype (DENV-2) on the expression profile of matrix metalloproteinases in THP-1, monocyte cells and their roles in endothelial dysfunctions: protective effect of atorvastatin.

Authors: Niranjan R Vidhyapriya P Murugasamy V et al.

Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Oct 20; Vol. 15, pp. 1632634. Date of Electronic Publication: 2025 Oct 20 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

MeSH Terms: Atorvastatin*/pharmacology , Monocytes*/virology , Monocytes*/drug effects , Monocytes*/metabolism , Dengue Virus*/drug effects , Dengue Virus*/classification , Matrix Metalloproteinases*/metabolism , Matrix Metalloproteinases*/genetics , Endothelial Cells*/drug effects , Endothelial Cells*/virology, Humans ; Animals ; Mice ; Dengue/virology ; Dengue/drug therapy ; THP-1 Cells ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase 9/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Serogroup ; Disease Models, Animal ; Matrix Metalloproteinase 2/genetics ; Matrix Metalloproteinase 2/metabolism ; Gene Expression Profiling ; Matrix Metalloproteinase 14/genetics ; Matrix Metalloproteinase 14/metabolism

Combination of atorvastatin and ticagrelor associated with rhabdomyolysis: A case report.

Authors: Li B Zhao L

Source: Medicine [Medicine (Baltimore)] 2025 Oct 10; Vol. 104 (41), pp. e45189.

Publication Type: Journal Article; Case Reports

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

MeSH Terms: Rhabdomyolysis*/chemically induced , Rhabdomyolysis*/therapy , Ticagrelor*/adverse effects , Ticagrelor*/administration & dosage , Atorvastatin*/adverse effects , Atorvastatin*/administration & dosage , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage, Humans ; Male ; Middle Aged ; Acute Coronary Syndrome/drug therapy ; Acute Coronary Syndrome/surgery ; Fatal Outcome ; Acute Kidney Injury/chemically induced ; Percutaneous Coronary Intervention ; Drug Therapy, Combination

Exploring the relationship between atorvastatin and rosuvastatin use and respiratory, thoracic, and mediastinal disorders: A retrospective study.

Authors: Tan T Lei Y Li C et al.

Source: Medicine [Medicine (Baltimore)] 2025 Oct 10; Vol. 104 (41), pp. e44984.

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

MeSH Terms: Atorvastatin*/adverse effects , Rosuvastatin Calcium*/adverse effects , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/adverse effects , Respiratory Tract Diseases*/chemically induced , Respiratory Tract Diseases*/epidemiology , Thoracic Diseases*/chemically induced , Thoracic Diseases*/epidemiology, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Pharmacovigilance ; Adult ; Aged ; Adverse Drug Reaction Reporting Systems/statistics & numerical data ; Adolescent ; Young Adult

Association of Ezetimibe and Statin Combinations With Recurrent Ischemic Stroke: A Nationwide Study With Dual Design.

Authors: Lee DH Park YA Choi SA et al.

Source: Journal of the American Heart Association [J Am Heart Assoc] 2025 Oct 07; Vol. 14 (19), pp. e038873. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE

MeSH Terms: Ezetimibe*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Ischemic Stroke*/epidemiology , Ischemic Stroke*/prevention & control , Ischemic Stroke*/diagnosis , Ischemic Stroke*/drug therapy , Rosuvastatin Calcium*/therapeutic use , Atorvastatin*/therapeutic use , Anticholesteremic Agents*/therapeutic use, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Republic of Korea/epidemiology ; Aged ; Recurrence ; Case-Control Studies ; Drug Therapy, Combination

Effects of Atorvastatin and Gemfibrozil on Mice Corpus Cavernosum In Vitro.

Authors: Erkoseoglu I Duman MK Kesim SM et al.

Source: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2025 Oct; Vol. 39 (5), pp. e70042.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Science Country of Publication: England NLM ID: 8710411 Publication Model: Print Cited Medium: Internet ISSN: 1472-8206 (Electronic) Linking ISSN: 07673981 NLM ISO Abbreviation: Fundam Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Atorvastatin*/pharmacology , Gemfibrozil*/pharmacology , Penis*/drug effects , Penis*/metabolism , Penile Erection*/drug effects , Hypolipidemic Agents*/pharmacology, Animals ; Male ; Mice ; Dose-Response Relationship, Drug ; In Vitro Techniques ; Muscle Relaxation/drug effects ; NG-Nitroarginine Methyl Ester/pharmacology

Preserved Cognitive Function After Statin Administration During Cancer Treatment With Doxorubicin: A Secondary Analysis of a Randomized Clinical Trial.

Authors: Grizzard PJ O'Connell NS Rapp SR et al.

Source: JAMA network open [JAMA Netw Open] 2025 Oct 01; Vol. 8 (10), pp. e2538325. Date of Electronic Publication: 2025 Oct 01.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE

MeSH Terms: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Doxorubicin*/adverse effects , Doxorubicin*/therapeutic use , Cognition*/drug effects , Atorvastatin*/therapeutic use , Atorvastatin*/administration & dosage , Breast Neoplasms*/drug therapy , Lymphoma*/drug therapy , Antibiotics, Antineoplastic*/adverse effects , Antibiotics, Antineoplastic*/therapeutic use, Humans ; Female ; Middle Aged ; Male ; Aged ; Adult ; Executive Function/drug effects

ADAMTS- 1 rs402007 Polymorphism Modulates Carotid Plaque Vulnerability and Atorvastatin Efficacy in Cerebral Infarction Patients.

Authors: Liu Y Deng Y Du Z et al.

Source: Translational stroke research [Transl Stroke Res] 2025 Oct; Vol. 16 (5), pp. 1792-1798. Date of Electronic Publication: 2025 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101517297 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1868-601X (Electronic) Linking ISSN: 18684483 NLM ISO Abbreviation: Transl Stroke Res Subsets: MEDLINE

MeSH Terms: Atorvastatin*/therapeutic use , Cerebral Infarction*/drug therapy , Cerebral Infarction*/genetics , Plaque, Atherosclerotic*/genetics , Plaque, Atherosclerotic*/drug therapy , Anticholesteremic Agents*/therapeutic use , Carotid Artery Diseases*/genetics , Carotid Artery Diseases*/drug therapy, Humans ; Male ; Female ; Middle Aged ; Aged ; Polymorphism, Single Nucleotide/genetics ; Genotype ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Treatment Outcome