Výsledky vyhľadávania - "Astrocytes/drug effects"

Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds

Autori: Kelly E. Carstens Elena Gronskaya David Jäckel a ďalší

Zdroj: Arch Toxicol
Archives of toxicology, vol. 99, no. 7, pp. 2917-2935

Predmety: In Vitro Systems, Humans, Induced Pluripotent Stem Cells/drug effects, Microelectrodes, Neurons/drug effects, Brain/drug effects, Brain/cytology, Toxicity Tests/methods, Astrocytes/drug effects, Environmental Pollutants/toxicity, Neurotoxicity Syndromes/etiology, Oligodendroglia/drug effects, Cells, Cultured, Microphysiological Systems, 3D cultures, BrainSphere, High-density electrode array, MEA, MPS, Microelectrode array, Neuronal electrical activity, Neurotoxicology, iPSC

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40293475
https://serval.unil.ch/notice/serval:BIB_76A6E3083DBE
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_76A6E3083DBE7
https://serval.unil.ch/resource/serval:BIB_76A6E3083DBE.P001/REF.pdf

Astrocyte Dysfunctions in Obsessive Compulsive Disorder: Rethinking Neurobiology and Therapeutic Targets

Autori: Gonzalez L. Bezzi P.

Zdroj: J Neurochem
Journal of neurochemistry, vol. 169, no. 5, pp. e70092

Predmety: Obsessive-Compulsive Disorder, OCD, astrocytes, psychiatric disorders, Neuronal Plasticity, Neurobiology, Astrocytes, REVIEW, Humans, Animals, Astrocytes/metabolism, Astrocytes/drug effects, Astrocytes/pathology, Obsessive-Compulsive Disorder/metabolism, Obsessive-Compulsive Disorder/physiopathology, Obsessive-Compulsive Disorder/drug therapy, Obsessive-Compulsive Disorder/therapy, Obsessive-Compulsive Disorder/pathology, Neuronal Plasticity/physiology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40400176
https://serval.unil.ch/notice/serval:BIB_B14759715279
https://serval.unil.ch/resource/serval:BIB_B14759715279.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B147597152794
https://hdl.handle.net/11573/1749038
https://doi.org/10.1111/jnc.70092

Consequences of a 2-Deoxyglucose Exposure on the ATP Content and the Cytosolic Glucose Metabolism of Cultured Primary Rat Astrocytes

Autori: Antonia Regina Harders Patrick Watermann Gabriele Karger a ďalší

Zdroj: Neurochem Res

Predmety: 0301 basic medicine, Original Paper, 0303 health sciences, Deoxyglucose, Deoxyglucose/metabolism [MeSH], Glycolysis/drug effects [MeSH], Glycolysis, Glucose, Rats [MeSH], Adenosine Triphosphate/metabolism [MeSH], Astrocytes/metabolism [MeSH], Astrocytes, Pentose phosphate pathway, Animals [MeSH], Glycolysis/physiology [MeSH], Astrocytes/drug effects [MeSH], Cytosol/metabolism [MeSH], Rats, Wistar [MeSH], Cells, Cultured [MeSH], Glucose/metabolism [MeSH], ATP, Deoxyglucose/pharmacology [MeSH], Rats, 03 medical and health sciences, Adenosine Triphosphate, Cytosol, Animals, Rats, Wistar, Cells, Cultured

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38898248
https://repository.publisso.de/resource/frl:6524588

Serotonin Effects on Human iPSC-Derived Neural Cell Functions: from Mitochondria to Depression

Autori: Cardon, Iseline Grobecker, Sonja Jenne, Frederike a ďalší

Zdroj: Mol Psychiatry

Predmety: Neurons, Adult, Male, 0301 basic medicine, ddc:610, Serotonin, Depressive Disorder, Major, 0303 health sciences, Depression, Induced Pluripotent Stem Cells, 610 Medizin, Middle Aged, Synaptic Transmission, Article, Antidepressive Agents, Mitochondria, 3. Good health, 03 medical and health sciences, 631/532, Depressive Disorder, Major/metabolism [MeSH], Synaptic Transmission/drug effects [MeSH], Astrocytes/drug effects [MeSH], Neurons/drug effects [MeSH], Synaptic Transmission/physiology [MeSH], 631/80, Male [MeSH], 13/100, Depression/metabolism [MeSH], 13/1, Female [MeSH], Serotonin/metabolism [MeSH], Calcium/metabolism [MeSH], Mitochondria/metabolism [MeSH], Adult [MeSH], Humans [MeSH], Neurons/metabolism [MeSH], 9/74, Astrocytes/metabolism [MeSH], Middle Aged [MeSH], Serotonin/pharmacology [MeSH], Induced Pluripotent Stem Cells/metabolism [MeSH], 9/10, 14/34, Mitochondria/drug effects [MeSH], 13/95, 631/378, Antidepressive Agents/pharmacology [MeSH], article, Induced Pluripotent Stem Cells/drug effects [MeSH], Astrocytes, Humans, Calcium, Female

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38532010
https://repository.publisso.de/resource/frl:6524232
https://epub.uni-regensburg.de/58045/

Differential Effects of Itaconate and its Esters on the Glutathione and Glucose Metabolism of Cultured Primary Rat Astrocytes

Autori: Patrick Watermann Gurleen K. Kalsi Ralf Dringen a ďalší

Zdroj: Neurochem Res

Predmety: Glucose, Cell Survival, Research, Astrocytes, Animals, Succinates, Esters, Rats, Wistar, Glutathione, Esters/pharmacology [MeSH], Glycolysis, Rats [MeSH], Cell Survival/drug effects [MeSH], Astrocytes/metabolism [MeSH], Succinates/metabolism [MeSH], Pentose-phosphate pathway, Animals [MeSH], Succinates/pharmacology [MeSH], Astrocytes/drug effects [MeSH], Glutathione/metabolism [MeSH], Rats, Wistar [MeSH], Itaconate, Cells, Cultured [MeSH], Glucose/metabolism [MeSH], Cells, Cultured, Rats

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39562371
https://repository.publisso.de/resource/frl:6493354

The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke

Autori: Olschewski, Daniel Navin Nazarzadeh, Nilufar Lange, Felix a ďalší

Zdroj: BMC Neurosci
BMC Neuroscience, Vol 25, Iss 1, Pp 1-19 (2024)
BMC neuroscience 25(1), 29 (2024). doi:10.1186/s12868-024-00876-x

Predmety: Neurophysiology and neuropsychology, 0301 basic medicine, Pyridines, Neurosciences. Biological psychiatry. Neuropsychiatry, Angiotensin II Type 2 Receptor Blockers, Cell Communication, Receptor, Angiotensin, Type 2, Receptor, Angiotensin, Type 1, Renin–angiotensin–aldosterone system, 03 medical and health sciences, Neuroinflammation, Cortical neuronal network, Animals, Telmisartan, Rats, Wistar, Cells, Cultured, Ischemic Stroke, Neurons, 0303 health sciences, Receptor, Angiotensin, Type 2/metabolism [MeSH], Microglia/drug effects [MeSH], Ischemic Stroke/metabolism [MeSH], Cell Communication/physiology [MeSH], Astrocytes, PD123319, Astrocytes/drug effects [MeSH], Neurons/drug effects [MeSH], Microglia/metabolism [MeSH], Telmisartan/pharmacology [MeSH], Cell Communication/drug effects [MeSH], Benzimidazoles/pharmacology [MeSH], Animals, Newborn [MeSH], Imidazoles/pharmacology [MeSH], Angiotensin II Type 2 Receptor Blockers/pharmacology [MeSH], Pyridines/pharmacology [MeSH], Neurons/metabolism [MeSH], Microglia, Rats [MeSH], Angiotensin II Type 1 Receptor Blockers/pharmacology [MeSH], Astrocytes/metabolism [MeSH], Animals [MeSH], Cerebral ischemia, Rats, Wistar [MeSH], Research, Ischemic Stroke/pathology [MeSH], Cells, Cultured [MeSH], Neuroinflammation and Brain Disease, MEA, Receptor, Angiotensin, Type 1/metabolism [MeSH], Microelectrode array, QP351-495, Imidazoles, Rats, 3. Good health, Animals, Newborn, Benzimidazoles, Angiotensin II Type 1 Receptor Blockers, RC321-571

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38926677
https://doaj.org/article/bc674676932a4f62ab2291b14f244c50
https://juser.fz-juelich.de/record/1028966
https://repository.publisso.de/resource/frl:6497061

Effects of Local Administration of Iron Oxide Nanoparticles in the Prefrontal Cortex, Striatum, and Hippocampus of Rats

Autori: Ellen Irrsack Julia Schuller Charlotte Petters a ďalší

Zdroj: Neurotox Res

Predmety: Male, Neurons, 0301 basic medicine, 0303 health sciences, Prefrontal Cortex, Hippocampus, Neurotoxicity, Immunocytochemistry, Microglia/drug effects [MeSH], Corpus Striatum/drug effects [MeSH], Rats [MeSH], Iron oxide nanoparticles, Animals [MeSH], Astrocytes/drug effects [MeSH], Magnetic Iron Oxide Nanoparticles/administration, Neurons/drug effects [MeSH], Rats, Wistar [MeSH], Original Article, Neurodegeneration, Male [MeSH], Glial cells, Hippocampus/drug effects [MeSH], Prefrontal Cortex/drug effects [MeSH], Injections, Intraventricular [MeSH], Corpus Striatum, Rats, 3. Good health, 03 medical and health sciences, Astrocytes, Animals, Magnetic Iron Oxide Nanoparticles, Microglia, Rats, Wistar, Injections, Intraventricular

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s12640-021-00432-z.pdf
https://pubmed.ncbi.nlm.nih.gov/34705254
https://paperity.org/p/274532406/effects-of-local-administration-of-iron-oxide-nanoparticles-in-the-prefrontal-cortex
https://link.springer.com/article/10.1007/s12640-021-00432-z
https://repository.publisso.de/resource/frl:6444212

β-Lapachone Induces Acute Oxidative Stress in Rat Primary Astrocyte Cultures that is Terminated by the NQO1-Inhibitor Dicoumarol

Autori: Johann Steinmeier Sophie Kube Gabriele Karger a ďalší

Zdroj: Neurochem Res

Predmety: 0301 basic medicine, Original Paper, Dicumarol, 0303 health sciences, NQO1, Naphthoquinones/adverse effects [MeSH], Dicoumarol, Reactive Oxygen Species/metabolism [MeSH], Cell Survival/drug effects [MeSH], Glutathione/chemistry [MeSH], Astrocytes, GSSG, Oxidation-Reduction [MeSH], Animals [MeSH], Astrocytes/drug effects [MeSH], Glutathione/metabolism [MeSH], Rats, Wistar [MeSH], Dicumarol/pharmacology [MeSH], Oxidative stress, Enzyme Inhibitors/pharmacology [MeSH], Neuroprotective Agents/pharmacology [MeSH], Oxidative Stress/drug effects [MeSH], NAD(P)H Dehydrogenase (Quinone)/antagonists, Cell Survival, Glutathione, 3. Good health, Oxidative Stress, 03 medical and health sciences, Neuroprotective Agents, NAD(P)H Dehydrogenase (Quinone), Animals, Enzyme Inhibitors, Rats, Wistar, Reactive Oxygen Species, Oxidation-Reduction, Naphthoquinones

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s11064-020-03104-0.pdf
https://pubmed.ncbi.nlm.nih.gov/32789798
https://europepmc.org/article/MED/32789798
https://pubmed.ncbi.nlm.nih.gov/32789798/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511478
https://link.springer.com/content/pdf/10.1007/s11064-020-03104-0.pdf
http://www.ncbi.nlm.nih.gov/pubmed/32789798
https://link.springer.com/article/10.1007/s11064-020-03104-0
https://repository.publisso.de/resource/frl:6470836

9-Methyl-β-carboline inhibits monoamine oxidase activity and stimulates the expression of neurotrophic factors by astrocytes

Autori: Sebastian Keller Gabriele Gille Witold H Polanski a ďalší

Zdroj: J Neural Transm (Vienna)
Journal of neural transmission 127(7), 999-1012 (2020). doi:10.1007/s00702-020-02189-9

Predmety: Dopaminergic Neurons [MeSH], Mice, Inbred C57BL [MeSH], Neurotrophic factors, Phosphatidylinositol 3-Kinases [MeSH], Nerve Growth Factors/metabolism [MeSH], Monoamine Oxidase Inhibitors/pharmacology [MeSH], Astrocytes, Animals [MeSH], Monoamine Oxidase [MeSH], Carbolines/pharmacology [MeSH], Astrocytes/drug effects [MeSH], Neurology and Preclinical Neurological Studies - Original Article, Dopaminergic neurons, Inhibition of monoamine oxidase A and B, 9-Methyl-β-carboline, Astrocytes/enzymology [MeSH], Cells, Cultured [MeSH], metabolism [Nerve Growth Factors], Monoamine Oxidase Inhibitors, Dopaminergic Neurons, drug effects [Astrocytes], pharmacology [Carbolines], enzymology [Astrocytes], Mice, Inbred C57BL, Phosphatidylinositol 3-Kinases, Animals, ddc:610, Nerve Growth Factors, Monoamine Oxidase, pharmacology [Monoamine Oxidase Inhibitors], Cells, Cultured, Carbolines

Prístupová URL adresa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592951
https://pubmed.ncbi.nlm.nih.gov/32285253
https://www.ncbi.nlm.nih.gov/pubmed/32285253
https://europepmc.org/article/PMC/PMC8592951
https://pubmed.ncbi.nlm.nih.gov/32285253/
https://link.springer.com/article/10.1007/s00702-020-02189-9
https://pub.dzne.de/record/151649
https://repository.publisso.de/resource/frl:6470388

Unusual astrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures.

Autori: Zurich, M.G. Lengacher, S. Braissant, O. a ďalší

Predmety: Animals, Astrocytes/drug effects, Astrocytes/physiology, Brain/cytology, Cell Aggregation/drug effects, Cells, Cultured, Culture Media, Serum-Free/pharmacology, Cyclic AMP/metabolism, Cyclic AMP/pharmacology, Dose-Response Relationship, Drug, Drug Interactions, Embryo, Mammalian, Extracellular Fluid/drug effects, Extracellular Fluid/metabolism, Gene Expression Regulation/drug effects, Glial Fibrillary Acidic Protein/genetics, Glial Fibrillary Acidic Protein/metabolism, Glutamate-Ammonia Ligase/genetics, Glutamate-Ammonia Ligase/metabolism, Heme Oxygenase (Decyclizing)/genetics, Heme Oxygenase (Decyclizing)/metabolism, Heme Oxygenase-1, Hydro-Lyases/metabolism, Immunohistochemistry/methods, In Situ Hybridization/methods, Mycotoxins/pharmacology

Relation: Neuroscience; 0306-4522[print], 0306-4522[linking]; https://iris.unil.ch/handle/iris/97651; serval:BIB_35682; 000231491200006

Dostupnosť: https://iris.unil.ch/handle/iris/97651
https://doi.org/10.1016/j.neuroscience.2005.04.030

Cyclooxygenase-2 in human and experimental ischemic proliferative retinopathy.

Autori: Sennlaub, F. Valamanesh, F. Vazquez-Tello, A. a ďalší

Predmety: Adult, Aged, Animals, Antigens, CD36/metabolism, Astrocytes/drug effects, Astrocytes/enzymology, Cell Division/drug effects, Cells, Cultured, Cyclooxygenase 2, Diabetic Retinopathy/complications, Diabetic Retinopathy/drug therapy, Dinoprostone/metabolism, Disease Models, Animal, Endothelial Growth Factors/metabolism, Enzyme Inhibitors/pharmacology, Female, Humans, Intercellular Signaling Peptides and Proteins/metabolism, Ischemia/complications, Ischemia/enzymology, Isoenzymes/antagonists & inhibitors, Isoenzymes/metabolism, Lymphokines/metabolism, Male, Membrane Proteins, Mice, Inbred C57BL

Popis súboru: application/pdf

Relation: Circulation; https://iris.unil.ch/handle/iris/72753; serval:BIB_3A50A6EB875D; 000184152900017

Dostupnosť: https://iris.unil.ch/handle/iris/72753
https://doi.org/10.1161/01.CIR.0000080735.93327.00

Maturation-dependent neurotoxicity of lead acetate in vitro: implication of glial reactions.

Autori: Zurich, M.G. Eskes, C. Honegger, P. a ďalší

Predmety: Animals, Astrocytes/cytology, Astrocytes/drug effects, Carbon Isotopes, Cell Differentiation/drug effects, Cells, Cultured, Choline O-Acetyltransferase/metabolism, Fetus, Glial Fibrillary Acidic Protein/metabolism, Glutamate Decarboxylase/metabolism, Glutamate Synthase/metabolism, Immunohistochemistry, Lectins/chemistry, Neuroglia/cytology, Neuroglia/drug effects, Neurons/cytology, Neurons/drug effects, Organometallic Compounds/toxicity, Rats, Telencephalon, Thymidine/metabolism

Relation: Journal of Neuroscience Research; 0360-4012[print], 0360-4012[linking]; https://iris.unil.ch/handle/iris/71001; serval:BIB_23011; 000178328800011

Dostupnosť: https://iris.unil.ch/handle/iris/71001
https://doi.org/10.1002/jnr.10367

Neuronal and astroglial monocarboxylate transporters play key but distinct roles in hippocampus-dependent learning and memory formation.

Autori: Netzahualcoyotzi, C. Pellerin, L.

Predmety: Animals, Astrocytes/drug effects, Astrocytes/metabolism, Behavior, Animal/physiology, Cognitive Dysfunction/drug therapy, Cognitive Dysfunction/metabolism, Cognitive Dysfunction/physiopathology, Genetic Vectors, Hippocampus/drug effects, Hippocampus/metabolism, Hippocampus/physiopathology, Lactic Acid/administration & dosage, Lactic Acid/pharmacology, Male, Mice, Inbred C57BL, Knockout, Monocarboxylic Acid Transporters, Muscle Proteins, Neurogenesis/drug effects, Neurogenesis/physiology, Neurons/drug effects, Neurons/metabolism, Spatial Learning/drug effects, Spatial Learning/physiology, Spatial Memory/drug effects, Spatial Memory/physiology, Conditional KO mouse, Lactate

Popis súboru: application/pdf

Relation: Progress in Neurobiology; https://iris.unil.ch/handle/iris/70265; serval:BIB_18C4DC876193; 000585063500011

Dostupnosť: https://iris.unil.ch/handle/iris/70265
https://doi.org/10.1016/j.pneurobio.2020.101888

Mitochondrial polarization in rat hippocampal astrocytes is resistant to cytosolic Ca(2+) loads

Autori: Kahlert, S. Schild, L. Reiser, G.

Predmety: Adenosine Triphosphate/metabolism Animals Animals, Newborn Astrocytes/drug effects/*metabolism Brain Ischemia/*metabolism/physiopathology Calcium/*metabolism Cells, Cultured Cytochrome c Group/metabolism/pharmacology Cytosol/drug effects/*metabolism Energy Metabolism/drug effects/*physiology Enzyme Inhibitors/pharmacology Fluorescent Dyes/diagnostic use Glycolysis/drug effects/physiology Hippocampus/drug effects/*metabolism/physiopathology Intracellular Membranes/drug effects/metabolism Ionophores/pharmacology Membrane Potentials/drug effects/physiology Membrane Transport Proteins/drug effects/physiology Mitochondria/drug effects/*metabolism Oxidative Phosphorylation/drug effects Rats Rats, Wistar

Relation: Journal of Neuroscience Research; https://iris.unil.ch/handle/iris/60929; serval:BIB_44BF3D8645D7; 000172562200037

Dostupnosť: https://iris.unil.ch/handle/iris/60929
https://doi.org/10.1002/jnr.10052

The naturally occurring food mycotoxin fumonisin B1 impairs myelin formation in aggregating brain cell culture.

Autori: Monnet-Tschudi, F. Zurich, M.G. Sorg, O. a ďalší

Predmety: Animals, Apoptosis/drug effects, Astrocytes/drug effects, Blotting, Western, Brain/cytology, Brain/drug effects, Carboxylic Acids/pharmacology, Cell Aggregation/drug effects, Cells, Cultured, Fumonisins, Glial Fibrillary Acidic Protein/biosynthesis, Immunohistochemistry, In Situ Nick-End Labeling, Microglia/drug effects, Microglia/ultrastructure, Mycotoxins/pharmacology, Myelin Basic Protein/biosynthesis, Myelin Basic Protein/metabolism, Myelin Sheath/drug effects, Neurons/drug effects, Oligodendroglia/drug effects, Rats, Thymidine/metabolism

Relation: NeuroToxicology; https://iris.unil.ch/handle/iris/52922; serval:BIB_2B01C2FA42D1; 000078809400004

Dostupnosť: https://iris.unil.ch/handle/iris/52922

Influence of epidermal growth factor on the maturation of fetal rat brain cells in aggregate culture. An immunocytochemical study.

Autori: Monnet-Tschudi, F. Honegger, P.

Predmety: Animals, Astrocytes/cytology, Astrocytes/drug effects, Biological Markers/analysis, Cell Aggregation/drug effects, Cell Differentiation/drug effects, Cells, Cultured, Epidermal Growth Factor/pharmacology, Fluorescent Antibody Technique, Galactosylceramides/analysis, Glial Fibrillary Acidic Protein/analysis, Immunohistochemistry, Intermediate Filaments/analysis, Neuroglia/drug effects, Neurons/cytology, Neurons/drug effects, Oligodendroglia/cytology, Oligodendroglia/drug effects, Phosphopyruvate Hydratase/analysis, Rats, Inbred Strains, Vimentin/analysis

Relation: Developmental Neuroscience; https://iris.unil.ch/handle/iris/42910; serval:BIB_32F047878DC9; A1989T525900004; 2653794

Dostupnosť: https://iris.unil.ch/handle/iris/42910
https://doi.org/10.1159/000111883

Arachidonic acid stimulates glucose uptake in cerebral cortical astrocytes

Autori: Yu, N. Martin, J. L. Stella, N. a ďalší

Predmety: Animals Animals, Newborn Arachidonic Acid/*metabolism/*pharmacology Astrocytes/drug effects/*metabolism Biological Transport/drug effects Cells, Cultured Cerebral Cortex/*metabolism Cytochalasin B/pharmacology Deoxyglucose/*metabolism Indomethacin/pharmacology Kinetics Linolenic Acids/pharmacology Melitten/pharmacology Mice Nordihydroguaiaretic Acid/pharmacology Norepinephrine/pharmacology Thimerosal/pharmacology Time Factors Vasoactive Intestinal Peptide/pharmacology

Relation: Proceedings of the National Academy of Sciences; https://iris.unil.ch/handle/iris/39869; serval:BIB_266BD4AE71A0; A1993LA43000056; 8483920

Dostupnosť: https://iris.unil.ch/handle/iris/39869
https://doi.org/10.1073/pnas.90.9.4042

Inhibition of glial cell proinflammatory activities by peroxisome proliferator-activated receptor gamma agonist confers partial protection during antimyelin oligodendrocyte glycoprotein demyelination in vitro.

Autori: Duvanel, C.B. Honegger, P. Pershadsingh, H. a ďalší

Predmety: Analysis of Variance, Animals, Antibodies, Monoclonal/pharmacology, Astrocytes/drug effects, Astrocytes/metabolism, Cells, Cultured, Complement System Proteins/immunology, Crystallins/drug effects, Crystallins/metabolism, Demyelinating Diseases/chemically induced, Dose-Response Relationship, Drug, Drug Interactions, Embryo, Mammalian, Glyceraldehyde-3-Phosphate Dehydrogenases/genetics, Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism, Heat-Shock Proteins/drug effects, Heat-Shock Proteins/metabolism, Heme Oxygenase (Decyclizing), Hypoglycemic Agents/pharmacology, Immunoglobulin G/pharmacology, Inflammation Mediators/physiology, Myelin Proteins, Myelin-Associated Glycoprotein/immunology, Myelin-Oligodendrocyte Glycoprotein, Neuroglia/drug effects, Neuroglia/physiology

Relation: Journal of Neuroscience Research; https://iris.unil.ch/handle/iris/39249; serval:BIB_1CF21763FEAE; 000180196500009

Dostupnosť: https://iris.unil.ch/handle/iris/39249
https://doi.org/10.1002/jnr.10471

Pro-inflammatory cytokines induce the transcription factors C/EBPbeta and C/EBPdelta in astrocytes.

Autori: Cardinaux, J.R. Allaman, I. Magistretti, P.J.

Predmety: Animals, Astrocytes/cytology, Astrocytes/drug effects, Blotting, Northern, CCAAT-Enhancer-Binding Proteins, Cells, Cultured, Cerebral Cortex/cytology, Complement C3/biosynthesis, Complement C3/genetics, Cycloheximide/pharmacology, Cytokines/metabolism, Cytokines/pharmacology, DNA-Binding Proteins/biosynthesis, DNA-Binding Proteins/genetics, Gene Expression/drug effects, Interferon-gamma/pharmacology, Interleukin-1/pharmacology, Interleukin-6/pharmacology, Lipopolysaccharides/pharmacology, Mice, Nuclear Proteins/biosynthesis, Nuclear Proteins/genetics, Protein Isoforms/biosynthesis, Protein Isoforms/genetics, Protein Synthesis Inhibitors/pharmacology, RNA, Messenger/biosynthesis, Serpins

Relation: Glia; https://iris.unil.ch/handle/iris/258477; serval:BIB_F0133DCB1181; 000084388600009

Dostupnosť: https://iris.unil.ch/handle/iris/258477

Glutamate uptake stimulates Na+,K+-ATPase activity in astrocytes via activation of a distinct subunit highly sensitive to ouabain

Autori: Pellerin, L. Magistretti, P. J.

Predmety: Animals Animals, Newborn Astrocytes/drug effects/*metabolism Biological Transport/drug effects Cells, Cultured Cerebral Cortex/*metabolism Enzyme Activation Glutamic Acid/*metabolism/*pharmacology Kinetics Macromolecular Substances Mice Na(+)-K(+)-Exchanging ATPase/chemistry/drug effects/*metabolism Ouabain/*pharmacology Regression Analysis Rubidium/pharmacokinetics

Relation: Journal of Neurochemistry; https://iris.unil.ch/handle/iris/242701; serval:BIB_F2285DC50508; A1997YC16800040; 9349559

Dostupnosť: https://iris.unil.ch/handle/iris/242701