Suchergebnisse - "Antitubercular Agents"

11,12-dihydrolactaroviolin from edible mushroom Lactarius hatsudake Tanaka as a selective inhibitor of Mycobacterium tuberculosis.

Autoren: Zhong P Bi L Chang S et al.

Quelle: Food chemistry [Food Chem] 2025 Dec 30; Vol. 497, pp. 146964. Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/genetics , Mycobacterium tuberculosis*/metabolism , Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Antitubercular Agents*/isolation & purification , Basidiomycota*/chemistry , Agaricales*/chemistry, Microbial Sensitivity Tests ; Molecular Docking Simulation ; Humans ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/chemistry ; Molecular Structure

Tet2 Protects Against Isoniazid-Induced Hepatotoxicity via Regulating Autophagy.

Autoren: Wang D Wang S Jin Z et al.

Quelle: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Dec 15; Vol. 39 (23), pp. e71300.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/drug effects , Isoniazid*/toxicity , Isoniazid*/adverse effects , Chemical and Drug Induced Liver Injury*/metabolism , Chemical and Drug Induced Liver Injury*/prevention & control , Chemical and Drug Induced Liver Injury*/pathology , Chemical and Drug Induced Liver Injury*/etiology , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics , Proto-Oncogene Proteins*/metabolism , Proto-Oncogene Proteins*/genetics , Antitubercular Agents*/toxicity , Antitubercular Agents*/adverse effects, Animals ; Dioxygenases/metabolism ; Mice ; Mice, Knockout ; Male ; Mice, Inbred C57BL ; Humans ; Hepatocytes/metabolism ; Hepatocytes/drug effects ; Liver/metabolism ; Liver/drug effects ; Liver/pathology

Validation and clinical application of an LC-MS/MS method designed to simultaneously measure seven second-line TB drugs and two metabolites in human lung tissue.

Autoren: Foster KK Pooran A van der Merwe M et al.

Quelle: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Dec 15; Vol. 266, pp. 117093. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/methods , Antitubercular Agents*/analysis , Antitubercular Agents*/metabolism , Lung*/metabolism, Humans ; Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Diarylquinolines/analysis ; Diarylquinolines/metabolism ; Nitroimidazoles/analysis ; Nitroimidazoles/metabolism ; Oxazoles/analysis ; Oxazoles/metabolism ; Limit of Detection ; Liquid Chromatography-Mass Spectrometry

The Oxidase Reaction of Flavin-Dependent Thymidylate Synthase Reveals the Nature of Inhibitor Binding.

Autoren: Ozcan SI Ly M Mostarshed N et al.

Quelle: Biochemistry [Biochemistry] 2025 Dec 02; Vol. 64 (23), pp. 4565-4570. Date of Electronic Publication: 2025 Nov 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

MeSH-Schlagworte: Thymidylate Synthase*/antagonists & inhibitors , Thymidylate Synthase*/chemistry , Oxidoreductases*/chemistry , Oxidoreductases*/metabolism , Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/enzymology , Antitubercular Agents*/chemistry , Antitubercular Agents*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/pharmacology , Naphthoquinones*/chemistry , Naphthoquinones*/pharmacology, Protein Binding ; Reactive Oxygen Species/antagonists & inhibitors ; Binding Sites/drug effects ; Catalytic Domain/drug effects ; Thymine Nucleotides/biosynthesis

Targeting nitroreductases for selective drug activation: therapeutic perspectives in neglected diseases and tuberculosis.

Autoren: Ruiz IG de Andrade ID Matuhara LYS et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109123. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Nitroreductases*/metabolism , Nitroreductases*/antagonists & inhibitors , Neglected Diseases*/drug therapy , Tuberculosis*/drug therapy , Antitubercular Agents*/chemistry , Antitubercular Agents*/pharmacology , Prodrugs*/chemistry , Prodrugs*/pharmacology , Prodrugs*/metabolism , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry, Humans ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/enzymology ; Structure-Activity Relationship ; Animals ; Molecular Structure

Quantitation of Plasma Bedaquiline Concentrations in Indian MDR-TB Patients Using Liquid Chromatography-Tandem Mass Spectrometry.

Autoren: Lokhande RV Arora PR Joubert A et al.

Körperschaften: Lokhande RV Arora PR Joubert A et al.

Quelle: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Dec; Vol. 39 (12), pp. e70243.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

MeSH-Schlagworte: Tandem Mass Spectrometry*/methods , Diarylquinolines*/blood , Diarylquinolines*/pharmacokinetics , Diarylquinolines*/therapeutic use , Diarylquinolines*/chemistry , Tuberculosis, Multidrug-Resistant*/drug therapy , Tuberculosis, Multidrug-Resistant*/blood , Antitubercular Agents*/blood , Antitubercular Agents*/pharmacokinetics , Antitubercular Agents*/therapeutic use, Humans ; India ; Reproducibility of Results ; Male ; Linear Models ; Chromatography, Liquid/methods ; Adult ; Female ; Limit of Detection ; Middle Aged ; Sensitivity and Specificity

Incidence and risk factors of abnormal liver function and anti-tuberculosis drug-induced liver injury: a multicenter retrospective study involving 482 chinese pediatric tuberculosis patients.

Autoren: Zhou Y Wang M Xu H et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2546701. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Chemical and Drug Induced Liver Injury*/epidemiology , Chemical and Drug Induced Liver Injury*/etiology , Antitubercular Agents*/adverse effects , Antitubercular Agents*/therapeutic use , Tuberculosis*/drug therapy, Humans ; Male ; Retrospective Studies ; Female ; Child ; Risk Factors ; Incidence ; Child, Preschool ; China/epidemiology ; Infant ; Adolescent ; Liver Function Tests ; Kaplan-Meier Estimate ; East Asian People

Design, synthesis, and biological evaluation of (E)-3-amino-N'-substituted benzylidene-6-chloropyrazine-2-carbohydrazide derivatives as anti-mycobacterial agents.

Autoren: Kumar BVS Bhardwaj P Chaudhari HS et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109206. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Mycobacterium tuberculosis*/drug effects , Drug Design* , Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemical synthesis , Antitubercular Agents*/chemistry , Hydrazines*/pharmacology , Hydrazines*/chemistry , Hydrazines*/chemical synthesis , Pyrazines*/pharmacology , Pyrazines*/chemistry , Pyrazines*/chemical synthesis , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Anti-Bacterial Agents*/chemistry, Microbial Sensitivity Tests ; Structure-Activity Relationship ; Molecular Structure ; Dose-Response Relationship, Drug ; Molecular Docking Simulation ; Humans

The new thiazolidine-2,4-dione-based hybrids with promising antimycobacterial activity: design, synthesis, biological evaluation, and drug interaction analysis.

Autoren: Trotsko N Głogowska A Kaproń B et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2442703. Date of Electronic Publication: 2025 Jan 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Microbial Sensitivity Tests* , Mycobacterium tuberculosis*/drug effects , Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemical synthesis , Antitubercular Agents*/chemistry , Drug Design* , Thiazolidinediones*/pharmacology , Thiazolidinediones*/chemistry , Thiazolidinediones*/chemical synthesis , Dose-Response Relationship, Drug*, Structure-Activity Relationship ; Molecular Structure ; Drug Interactions

All-Oral Shorter Treatment Regimens for Multidrug- and Rifampicin-Resistant Tuberculosis: Evaluating Their Effectiveness, Safety, and Impact on the Quality of Life of Patients in Lao PDR.

Autoren: Iem V Suthepmany S Inthavong V et al.

Quelle: Tropical medicine & international health : TM & IH [Trop Med Int Health] 2025 Dec; Vol. 30 (12), pp. 1340-1353. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9610576 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3156 (Electronic) Linking ISSN: 13602276 NLM ISO Abbreviation: Trop Med Int Health Subsets: MEDLINE

MeSH-Schlagworte: Tuberculosis, Multidrug-Resistant*/drug therapy , Quality of Life* , Rifampin*/therapeutic use , Antitubercular Agents*/administration & dosage , Antitubercular Agents*/adverse effects , Antitubercular Agents*/therapeutic use, Humans ; Male ; Female ; Laos ; Adult ; Retrospective Studies ; Middle Aged ; Prospective Studies ; Administration, Oral ; Treatment Outcome

Late-onset paradoxical response 11 years after treatment of tuberculous hepatic abscesses in an HIV-negative patient: a case report and literature review.

Autoren: Suzue K Tanaka Y Akazawa N et al.

Quelle: Clinical journal of gastroenterology [Clin J Gastroenterol] 2025 Dec; Vol. 18 (6), pp. 1083-1088. Date of Electronic Publication: 2025 Aug 31.

Publikationsart: Journal Article; Case Reports; Review

Info zur Zeitschrift: Publisher: Springer Japan Country of Publication: Japan NLM ID: 101477246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-7265 (Electronic) Linking ISSN: 18657265 NLM ISO Abbreviation: Clin J Gastroenterol Subsets: MEDLINE

MeSH-Schlagworte: Antitubercular Agents*/therapeutic use , Antitubercular Agents*/adverse effects , Liver Abscess*/drug therapy , Liver Abscess*/microbiology , Tuberculosis, Hepatic*/drug therapy, Humans ; Female ; Middle Aged ; HIV Seronegativity ; Time Factors ; Tomography, X-Ray Computed

Inhibitors of NADH-O-methylquinone compound a class of antitubercular drugs.

Autoren: Lin D Xu C Gan C et al.

Quelle: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 5823-5833. Date of Electronic Publication: 2025 Jan 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

MeSH-Schlagworte: Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Mycobacterium marinum*/drug effects , Mycobacterium marinum*/metabolism , NAD*/metabolism , Hydroquinones*/pharmacology , Hydroquinones*/chemistry, Reactive Oxygen Species/metabolism ; Microbial Sensitivity Tests ; Oxidation-Reduction/drug effects

Predictors of therapeutic exposure and pharmacokinetic variability of second-line anti-TB drugs in MDR-TB patients: a retrospective study.

Autoren: Quncuo C Ye WD Yang J et al.

Quelle: Infection [Infection] 2025 Dec; Vol. 53 (6), pp. 2717-2726. Date of Electronic Publication: 2025 Aug 13.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Springer Heidelberg Country of Publication: Germany NLM ID: 0365307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0973 (Electronic) Linking ISSN: 03008126 NLM ISO Abbreviation: Infection Subsets: MEDLINE

MeSH-Schlagworte: Tuberculosis, Multidrug-Resistant*/drug therapy , Tuberculosis, Multidrug-Resistant*/blood , Antitubercular Agents*/pharmacokinetics , Antitubercular Agents*/therapeutic use , Antitubercular Agents*/blood, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Adult ; Drug Monitoring ; Aged ; Levofloxacin/pharmacokinetics ; Levofloxacin/therapeutic use ; Levofloxacin/blood ; Cycloserine/pharmacokinetics ; Cycloserine/therapeutic use ; Cycloserine/blood ; China ; Linezolid/pharmacokinetics ; Linezolid/therapeutic use ; Linezolid/blood ; Clofazimine/pharmacokinetics ; Clofazimine/therapeutic use ; Clofazimine/blood ; Young Adult ; Diarylquinolines

The clinical profile of patients with indeterminate Xpert rifampin resistance results in a single tertiary level institution.

Autoren: Tenorio BG Uayan DJ Lumunsad KF et al.

Quelle: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2025 Dec; Vol. 113 (4), pp. 117008. Date of Electronic Publication: 2025 Jul 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8305899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0070 (Electronic) Linking ISSN: 07328893 NLM ISO Abbreviation: Diagn Microbiol Infect Dis Subsets: MEDLINE

MeSH-Schlagworte: Rifampin*/pharmacology , Rifampin*/therapeutic use , Drug Resistance, Bacterial* , Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/genetics , Mycobacterium tuberculosis*/isolation & purification , Antitubercular Agents*/pharmacology , Antitubercular Agents*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Adult ; Tertiary Care Centers ; Aged ; Microbial Sensitivity Tests ; Retrospective Studies ; Molecular Diagnostic Techniques ; Young Adult ; Antibiotics, Antitubercular/pharmacology

Genetic and clinical risk factors for anti-tuberculosis drug-induced liver injury: insights from a prospective cohort study in central Ethiopia.

Autoren: Klindt C Fuchs A Behnke K et al.

Quelle: Infection [Infection] 2025 Dec; Vol. 53 (6), pp. 2833-2846. Date of Electronic Publication: 2025 Sep 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Heidelberg Country of Publication: Germany NLM ID: 0365307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0973 (Electronic) Linking ISSN: 03008126 NLM ISO Abbreviation: Infection Subsets: MEDLINE

MeSH-Schlagworte: Antitubercular Agents*/adverse effects , Antitubercular Agents*/therapeutic use , Chemical and Drug Induced Liver Injury*/genetics , Chemical and Drug Induced Liver Injury*/epidemiology , Chemical and Drug Induced Liver Injury*/etiology , Tuberculosis*/drug therapy, Humans ; Ethiopia/epidemiology ; Male ; Female ; Prospective Studies ; Adult ; Risk Factors ; Middle Aged ; Young Adult ; Incidence ; Adolescent

Clinical perspective of multiple drug resistance tuberculosis: An overview.

Autoren: Raj A Abbot V Kumar K

Quelle: Microbial pathogenesis [Microb Pathog] 2025 Dec; Vol. 209, pp. 108115. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: England NLM ID: 8606191 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1208 (Electronic) Linking ISSN: 08824010 NLM ISO Abbreviation: Microb Pathog Subsets: MEDLINE

MeSH-Schlagworte: Antitubercular Agents*/pharmacology , Antitubercular Agents*/therapeutic use , Mycobacterium tuberculosis*/drug effects , Tuberculosis, Multidrug-Resistant*/drug therapy , Tuberculosis, Multidrug-Resistant*/diagnosis , Tuberculosis, Multidrug-Resistant*/microbiology , Drug Resistance, Multiple, Bacterial*, Humans ; Nanotechnology ; Nanoparticles

Adverse drug reactions, particularly liver disorders, drive interruptions in anti-tuberculosis treatment: A retrospective cohort study.

Autoren: Dixon EG Biraua E Brencsēns E et al.

Quelle: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Dec; Vol. 91 (12), pp. 3461-3470. Date of Electronic Publication: 2025 Aug 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Antitubercular Agents*/adverse effects , Antitubercular Agents*/administration & dosage , Tuberculosis*/drug therapy , Chemical and Drug Induced Liver Injury*/epidemiology , Chemical and Drug Induced Liver Injury*/etiology , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Liver Diseases*/epidemiology, Humans ; Retrospective Studies ; Male ; Female ; Adult ; Middle Aged ; Aged ; Latvia/epidemiology ; Young Adult

Structural isomerisation affects the antitubercular activity of adamantyl-isoxyl adducts.

Autoren: Lu Y Partleton D Gugu FM et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2502600. Date of Electronic Publication: 2025 May 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Antitubercular Agents*/chemical synthesis , Mycobacterium tuberculosis*/drug effects , Adamantane*/pharmacology , Adamantane*/chemistry , Adamantane*/analogs & derivatives, Structure-Activity Relationship ; Microbial Sensitivity Tests ; Molecular Structure ; Dose-Response Relationship, Drug ; Isomerism ; Humans

Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study.

Autoren: Liu Y Zhang Y Lu X et al.

Quelle: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2534656. Date of Electronic Publication: 2025 Aug 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

MeSH-Schlagworte: Tuberculosis, Multidrug-Resistant*/epidemiology , Tuberculosis, Multidrug-Resistant*/microbiology , Tuberculosis, Multidrug-Resistant*/drug therapy , Mycobacterium tuberculosis*/genetics , Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/isolation & purification , Antitubercular Agents*/pharmacology , Antitubercular Agents*/therapeutic use , Drug Resistance, Multiple, Bacterial*/genetics , Coinfection*/epidemiology , Coinfection*/microbiology, Humans ; China/epidemiology ; Male ; Female ; Middle Aged ; Adult ; Aged ; Genotype ; Young Adult ; Microbial Sensitivity Tests ; Molecular Epidemiology ; Prevalence ; Adolescent

Targeting HspX of Mycobacterium tuberculosis: Advances in diagnostics, treatment, and vaccine development.

Autoren: Hidalgo-Gajardo A Mangui B Villavicencio C et al.

Quelle: Tuberculosis (Edinburgh, Scotland) [Tuberculosis (Edinb)] 2025 Dec; Vol. 155, pp. 102702. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 100971555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-281X (Electronic) Linking ISSN: 14729792 NLM ISO Abbreviation: Tuberculosis (Edinb) Subsets: MEDLINE

MeSH-Schlagworte: Mycobacterium tuberculosis*/immunology , Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/pathogenicity , Mycobacterium tuberculosis*/metabolism , Tuberculosis Vaccines*/immunology , Bacterial Proteins*/immunology , Bacterial Proteins*/metabolism , Vaccine Development* , alpha-Crystallins*/immunology , alpha-Crystallins*/metabolism , Antitubercular Agents*/therapeutic use , Antitubercular Agents*/adverse effects , Antigens, Bacterial*/immunology , Tuberculosis*/diagnosis , Tuberculosis*/immunology , Tuberculosis*/prevention & control , Tuberculosis*/microbiology, Humans ; Animals ; Latent Tuberculosis/immunology ; Latent Tuberculosis/diagnosis ; Latent Tuberculosis/microbiology