Výsledky vyhľadávania - "Antibodies, Neutralizing/immunology"

Relevance of Neutralizing Antibodies for the Pharmacokinetics of Pegunigalsidase Alfa in Patients with Fabry Disease

Autori: Malte Lenders Elise Raphaela Menke Michael Rudnicki a ďalší

Zdroj: BioDrugs

Predmety: Half-Life [MeSH], Aged [MeSH], Recombinant Proteins/pharmacokinetics [MeSH], alpha-Galactosidase/pharmacokinetics [MeSH], alpha-Galactosidase/therapeutic use [MeSH], Enzyme Replacement Therapy/methods [MeSH], Antibodies, Neutralizing/immunology [MeSH], Male [MeSH], Polyethylene Glycols/pharmacokinetics [MeSH], Fabry Disease/immunology [MeSH], Original Research Article, Isoenzymes/therapeutic use [MeSH], Adolescent [MeSH], Female [MeSH], Isoenzymes/pharmacokinetics [MeSH], Adult [MeSH], Humans [MeSH], alpha-Galactosidase/immunology [MeSH], Middle Aged [MeSH], alpha-Galactosidase/administration, Isoenzymes/immunology [MeSH], Recombinant Proteins/administration, Recombinant Proteins/therapeutic use [MeSH], Young Adult [MeSH], Fabry Disease/drug therapy [MeSH]

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39614966
https://repository.publisso.de/resource/frl:6501624

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base

Autori: De Cae, Sieglinde Van Molle, Inge van Schie, Loes a ďalší

Prispievatelia: De Cae, Sieglinde Van Molle, Inge van Schie, Loes a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 16, Iss 1, Pp 1-22 (2025)
NATURE COMMUNICATIONS

Predmety: mice, Science, Epitopes/immunology, SARS-COV-2, Antibodies, Viral, SARS-CoV-2/immunology, Article, REGION, Mice, Epitopes, SDG 3 - Good Health and Well-being, Medicine and Health Sciences, Humans, Animals, Antibodies, Viral/immunology, HR2, EXCHANGE, SITES, Science & Technology, SARS-CoV-2, Biology and Life Sciences, Single-Domain Antibodies/immunology, COVID-19, AUTOPROC, Single-Domain Antibodies, Antibodies, Neutralizing/immunology, Antibodies, Neutralizing, COVID-19/immunology, Multidisciplinary Sciences, HEK293 Cells, Severe acute respiratory syndrome-related coronavirus, Spike Glycoprotein, Coronavirus, Science & Technology - Other Topics, Spike Glycoprotein, Coronavirus/immunology, Female, Severe acute respiratory syndrome-related coronavirus/immunology

Popis súboru: application/pdf

Prístupová URL adresa: https://doaj.org/article/3f3f53d840984852b9c64bc832a5340f
https://biblio.vub.ac.be/vubir/ultrapotent-sars-coronavirusneutralizing-singledomain-antibodies-that-clamp-the-spike-at-its-base(77d17c42-6556-47b9-a42d-1d03b52eb1cc).html
https://biblio.ugent.be/publication/01K0Y9XR7PYRG04KSAN7CACSKA
https://biblio.ugent.be/publication/01K0Y9XR7PYRG04KSAN7CACSKA/file/01K0YAT4170ZJ38HB4M10M33YX
http://doi.org/10.1038/s41467-025-60250-1
http://hdl.handle.net/1854/LU-01K0Y9XR7PYRG04KSAN7CACSKA

Type I interferon autoantibody footprints reveal neutralizing mechanisms and allow inhibitory decoy design

Autori: Kevin Groen Roger Kuratli Jannik Enkelmann a ďalší

Prispievatelia: Kevin Groen Roger Kuratli Jannik Enkelmann a ďalší

Zdroj: J Exp Med
The Journal of experimental medicine, vol. 222, no. 6

Predmety: HEK293 Cells, SARS-CoV-2, Interferon Type I, HIV-1, Humans, COVID-19, HIV Infections, Autoantibodies/immunology, Autoantibodies/blood, Antibodies, Neutralizing/immunology, Interferon Type I/immunology, COVID-19/immunology, Receptor, Interferon alpha-beta/immunology, Receptor, Interferon alpha-beta/metabolism, SARS-CoV-2/immunology, HIV-1/immunology, HIV Infections/immunology, Receptor, Interferon alpha-beta, Antibodies, Neutralizing, Article, Autoantibodies

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40111224
https://serval.unil.ch/notice/serval:BIB_E3151BDE2BDE
https://serval.unil.ch/resource/serval:BIB_E3151BDE2BDE.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E3151BDE2BDE8

Convalescent Plasma for Covid-19–Induced ARDS in Mechanically Ventilated Patients

Autori: Misset, Benoît Piagnerelli, Michael Hoste, Eric a ďalší

Prispievatelia: Misset, Benoît Piagnerelli, Michael Hoste, Eric a ďalší

Zdroj: N Engl J Med
The New England journal of medicine, Vol. 389, no. 17, p. 1590-1600 (2023)
The New England journal of medicine
NEW ENGLAND JOURNAL OF MEDICINE

Predmety: Adult, Anesthésie & soins intensifs, Critical Care, Mechanical Ventilation, Infectious Disease, Global Health, Sciences de la santé humaine, Respiratory Distress Syndrome/etiology, Medicine and Health Sciences, Humans, Human health sciences, COVID-19 Serotherapy, Respiratory Distress Syndrome, Pulmonary/Critical Care General, SARS-CoV-2, MORTALITY, COVID-19, General Medicine, Sciences bio-médicales et agricoles, Anesthesia & intensive care, Antibodies, Neutralizing/immunology, Antibodies, Neutralizing, Respiration, Artificial, 3. Good health, Viral Infections, Coronavirus, Pulmonary/Critical Care, Treatment Outcome, COVID-19/complications, Original Article, Human medicine, Infectious Disease General

Popis súboru: application/pdf; 1 full-text file(s): application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37889107
https://hdl.handle.net/2078.1/279784
https://hdl.handle.net/10067/2012020151162165141
https://biblio.vub.ac.be/vubir/convalescent-plasma-for-covid19induced-ards-in-mechanically-ventilated-patients(b1db439c-cf5c-4699-944e-23023a0f2232).html
https://biblio.ugent.be/publication/01HK76T5Y3MY2MM1ZMQET7DNZ8/file/01HK7CSJMY9HBY7REAFS2RFX2T
http://hdl.handle.net/1854/LU-01HK76T5Y3MY2MM1ZMQET7DNZ8
https://biblio.ugent.be/publication/01HK76T5Y3MY2MM1ZMQET7DNZ8
http://doi.org/10.1056/NEJMoa2209502

Natural and hybrid immunity after SARS-CoV-2 infection in children and adolescents

Autori: Rothoeft, T. Maier, C. Talarico, A. a ďalší

Zdroj: Infection

Predmety: Male, 0301 basic medicine, ddc:610, Immunity, Cellular, 0303 health sciences, COVID-19 Vaccines, Adolescent, SARS-CoV-2, Research, COVID-19, COVID-19/immunology [MeSH], Antibodies, Neutralizing/blood [MeSH], T cell, Immunity, Humoral [MeSH], COVID-19 Vaccines/immunology [MeSH], Antibodies, Neutralizing/immunology [MeSH], Male [MeSH], SARS-CoV-2/immunology [MeSH], Immunity, Innate [MeSH], Coronavirus Nucleocapsid Proteins/immunology [MeSH], Child [MeSH], Antibodies, Viral/blood [MeSH], Adolescent [MeSH], Female [MeSH], Immunity, Cellular [MeSH], Humans [MeSH], Vaccination, Antibody, Children, Immunity, Convalescent, Spike Glycoprotein, Coronavirus/immunology [MeSH], Child, Preschool [MeSH], Antibodies, Viral, Antibodies, Neutralizing, Immunity, Innate, Immunity, Humoral, 3. Good health, 03 medical and health sciences, Child, Preschool, Spike Glycoprotein, Coronavirus, Humans, Coronavirus Nucleocapsid Proteins, Female, Child

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38499828
https://nbn-resolving.org/urn:nbn:de:hbz:294-113259
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/11325/RothoeftTobias18032024.pdf
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/11325
https://repository.publisso.de/resource/frl:6504215

Adenoviral fiber-knob based vaccination elicits efficient neutralizing antibodies and T cell responses against adenovirus infection

Autori: Orabi, Ahmed Shameli, Kamyar Protzer, Ulrike a ďalší

Zdroj: Virol J
Virology Journal, Vol 21, Iss 1, Pp 1-10 (2024)

Predmety: T-Lymphocytes, Adenoviridae Infections, Infectious and parasitic diseases, RC109-216, Neutralizing antibodies, Antibodies, Viral, Adenovirus Infections, Human, Mice, Adenovirus Vaccines, Animals, Humans, Research, Adenoviral vaccination, Fiber-knob, CD4, Adenovirus infection, Mice, Inbred BALB C, Adenoviruses, Human, Vaccination, Antibodies, Neutralizing, ddc, Adenoviridae Infections/prevention, Antibodies, Viral/immunology [MeSH], Mice, Inbred BALB C [MeSH], Capsid Proteins/genetics [MeSH], Adenovirus Infections, Human/prevention, Adenovirus Vaccines/administration, Antibodies, Neutralizing/immunology [MeSH], Adenoviruses, Human/immunology [MeSH], Adenoviridae Infections/immunology [MeSH], Female [MeSH], Adenovirus Vaccines/immunology [MeSH], Adenovirus Infections, Human/immunology [MeSH], T-Lymphocytes/immunology [MeSH], Humans [MeSH], Animals [MeSH], Mice [MeSH], HEK293 Cells [MeSH], Adenoviruses, Human/genetics [MeSH], Vaccination [MeSH], Adenovirus Infections, Human/virology [MeSH], Capsid Proteins/immunology [MeSH], HEK293 Cells, CD4+ T cell responses, Capsid Proteins, Female

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39370512
https://doaj.org/article/336c3f3954434751972ddb3955a2cfb9
https://repository.publisso.de/resource/frl:6490688
https://mediatum.ub.tum.de/doc/1770401/document.pdf

Personalized prediction of SARS-CoV-2 vaccine-induced immunity after boost: a longitudinal analysis using joint modeling.

Autori: Papadopoulos, Iraklis Diep, Anh Nguyet Schyns, Joey a ďalší

Zdroj: Frontiers in Immunology, 16, 1619631 (2025)

Predmety: SARS-CoV-2, breakthrough infection, immune response, joint modelling, prediction, COVID-19 Vaccines, Antibodies, Viral, Antibodies, Neutralizing, Immunoglobulin G, Spike Glycoprotein, Coronavirus, Humans, Longitudinal Studies, Antibodies, Viral/blood, Antibodies, Viral/immunology, Antibodies, Neutralizing/blood, Antibodies, Neutralizing/immunology, Female, Male, Middle Aged, Adult, Immunoglobulin G/blood, Immunoglobulin G/immunology, Models, Statistical, Precision Medicine, Aged, Spike Glycoprotein, Coronavirus/immunology, SARS-CoV-2/immunology, COVID-19/immunology, COVID-19/prevention & control, COVID-19 Vaccines/immunology, COVID-19 Vaccines/administration & dosage, Immunization, Secondary, Human health sciences, Immunology & infectious disease, Sciences de la santé humaine, Immunologie & maladie infectieuse

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1619631/full; urn:issn:1664-3224

Prístupová URL adresa: https://orbi.uliege.be/handle/2268/337078

Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies

Autori: Sonja Fernbach Nina K. Mair Irene A. Abela a ďalší

Prispievatelia: Sonja Fernbach Nina K. Mair Irene A. Abela a ďalší

Zdroj: J Exp Med
The Journal of experimental medicine, vol. 221, no. 9
Fernbach, Sonja; Mair, Nina K; Abela, Irene A; Groen, Kevin; Kuratli, Roger; Lork, Marie; Thorball, Christian W; Bernasconi, Enos; Filippidis, Paraskevas; Leuzinger, Karoline; Notter, Julia; Rauch, Andri; Hirsch, Hans H; Huber, Michael; Günthard, Huldrych F; Fellay, Jacques; Kouyos, Roger D; Hale, Benjamin G (2024). Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies. Journal of experimental medicine, 221(9) Rockefeller University Press 10.1084/jem.20240365 <http://dx.doi.org/10.1084/jem.20240365>

Predmety: Male, Adult, 0301 basic medicine, 0303 health sciences, Humans, Autoantibodies/immunology, Interferon Type I/immunology, Middle Aged, Female, COVID-19/immunology, Antibodies, Neutralizing/immunology, Aged, SARS-CoV-2/immunology, HIV Infections/immunology, Interferon-alpha/immunology, Retrospective Studies, SARS-CoV-2, COVID-19, Interferon-alpha, 610 Medicine & health, HIV Infections, Antibodies, Neutralizing, Article, 03 medical and health sciences, Interferon Type I, Autoantibodies

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39017930
https://serval.unil.ch/notice/serval:BIB_091D90E14C02
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_091D90E14C029
https://serval.unil.ch/resource/serval:BIB_091D90E14C02.P001/REF.pdf
https://boris.unibe.ch/199073/

Neutralizing Antibody Sample Testing and Report Harmonization

Autori: Darshana Jani Michele Gunsior Robin Marsden a ďalší

Zdroj: The AAPS Journal. 26

Predmety: 0301 basic medicine, 03 medical and health sciences, 0302 clinical medicine, multi-functional therapeutics, Antibodies, Neutralizing/immunology [MeSH], neutralizing antibody, immunogenicity, Antibodies, Neutralizing/blood [MeSH], Humans [MeSH], White Paper, template, bioanalytical report, Humans, Antibodies, Neutralizing, 3. Good health

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38992280
https://repository.publisso.de/resource/frl:6520449

Neutralizing antibody responses assessment after vaccination in people living with HIV using a surrogate neutralization assay

Autori: Batchi-Bouyou, Armel Landry Djontu, Jean Claude Ingoba, Line Lobaloba a ďalší

Zdroj: BMC Immunol
BMC Immunology, Vol 25, Iss 1, Pp 1-9 (2024)
BMC Immunology

Predmety: Sinopharm/BBIP-CorV, COVID-19, Antibodies, Viral/immunology [MeSH], COVID-19/immunology [MeSH], Antibodies, Neutralizing/blood [MeSH], Vaccine, COVID-19 Vaccines/immunology [MeSH], Antibodies, Neutralizing/immunology [MeSH], Male [MeSH], SARS-CoV-2/immunology [MeSH], SARS-CoV-2, Antibodies, Antibodies, Viral/blood [MeSH], Female [MeSH], Cellular immunology and HIV, Neutralization Tests [MeSH], Adult [MeSH], HIV Infections/immunology [MeSH], Humans [MeSH], Janssen/Ad26.COV2.S, Middle Aged [MeSH], COVID-19/prevention, HIV Infections/drug therapy [MeSH], Research, Vaccination [MeSH], Republic of the Congo, Male, Adult, 0301 basic medicine, COVID-19 Vaccines, HIV Infections, Antibodies, Viral, 03 medical and health sciences, Neutralization Tests, Humans, 0303 health sciences, Vaccination, RC581-607, Middle Aged, 16. Peace & justice, Antibodies, Neutralizing, 3. Good health, Female, Immunologic diseases. Allergy

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38987686
https://doaj.org/article/5b3aebe124bd4405845b055d5aaacc02
https://repository.publisso.de/resource/frl:6493342

Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer

Autori: Schleich, Fabian-Alexander Bale, Shridhar Guenaga, Javier a ďalší

Zdroj: Schleich, F-A, Bale, S, Guenaga, J, Ozorowski, G, Àdori, M, Lin, X, Castro Dopico, X, Wilson, R, Chernyshev, M, Cotgreave, A T, Mandolesi, M, Cluff, J, Doyle, E D, Sewall, L M, Lee, W-H, Zhang, S, O'Dell, S, Healy, B S, Lim, D, Lewis, V R, Ben-Akiva, E, Irvine, D J, Doria-Rose, N A, Corcoran, M, Carnathan, D, Silvestri, G, Wilson, I A, Ward, A B, Karlsson Hedestam, G B & Wyatt, R T 2025, 'Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer', Immunity, vol. 58, no. 6, pp. 1598-1613.e8. https://doi.org/10.1016/j.immuni.2025.04.010

Predmety: HIV-1 neutralization, CD4 Antigens/immunology, Cryoelectron Microscopy, Vaccination, Env trimers, IG genotyping, Epitopes/immunology, germline, vaccination, Antibodies, Neutralizing/immunology, HIV Envelope Protein gp120/immunology, Macaca mulatta, env Gene Products, Human Immunodeficiency Virus/immunology, Broadly Neutralizing Antibodies/immunology, HIV Infections/immunology, HIV-1/immunology, Animals, HIV Antibodies/immunology, Humans, AIDS Vaccines/immunology, monoclonal antibodies, Cross Reactions/immunology

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40339576

RAIN: machine learning-based identification for HIV-1 bNAbs

Autori: Mathilde Foglierini Pauline Nortier Rachel Schelling a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Nature communications, vol. 15, no. 1, pp. 5339

Predmety: Science, Cryoelectron Microscopy, HIV Infections, HIV Antibodies, HIV Envelope Protein gp120, Antibodies, Neutralizing, Article, 3. Good health, Machine Learning, CD4 Antigens, HIV-1/immunology, Humans, HIV Antibodies/immunology, Antibodies, Neutralizing/immunology, HIV Infections/virology, HIV Infections/immunology, CD4 Antigens/metabolism, CD4 Antigens/immunology, Amino Acid Sequence, HIV Envelope Protein gp120/immunology, HIV Envelope Protein gp120/chemistry, HIV-1

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38914562
https://doaj.org/article/9d102f79207c417eb04c2d3080c48cb2
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_7E00114027847
https://serval.unil.ch/resource/serval:BIB_7E0011402784.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_7E0011402784

Antibody and T-Cell Response to Bivalent Booster SARS-CoV-2 Vaccines in People With Compromised Immune Function: COVERALL-3 Study

Autori: Alain Amstutz Frédérique Chammartin Annette Audigé a ďalší

Prispievatelia: Alain Amstutz Frédérique Chammartin Annette Audigé a ďalší

Zdroj: J Infect Dis
The Journal of infectious diseases, vol. 230, no. 4, pp. e847-e859
Amstutz, Alain; Chammartin, Frédérique; Audigé, Annette; Eichenberger, Anna L; Braun, Dominique L; Amico, Patrizia; Stoeckle, Marcel P; Hasse, Barbara; Papadimitriou-Olivgeris, Matthaios; Manuel, Oriol; Bongard, Cédric; Schuurmans, Macé M; Hage, René; Damm, Dominik; Tamm, Michael; Mueller, Nicolas J; Rauch, Andri; Günthard, Huldrych F; Koller, Michael T; Schönenberger, Christof M; ... (2024). Antibody and T-cell response to bivalent booster SARS-CoV-2 vaccines in people with compromised immune function (COVERALL-3). The journal of infectious diseases, 230(4), e847-e859. Oxford University Press 10.1093/infdis/jiae291 <http://dx.doi.org/10.1093/infdis/jiae291>
Amstutz, Alain; Chammartin, Frédérique; Audigé, Annette; Eichenberger, Anna L; Braun, Dominique L; Amico, Patrizia; Stoeckle, Marcel P; Hasse, Barbara; Papadimitriou-Olivgeris, Matthaios; Manuel, Oriol; Bongard, Cédric; Schuurmans, Macé M; Hage, René; Damm, Dominik; Tamm, Michael; Mueller, Nicolas J; Rauch, Andri; Günthard, Huldrych F; Koller, Michael T; Schönenberger, Christof M; ... (2024). Antibody and T-cell response to bivalent booster SARS-CoV-2 vaccines in people with compromised immune function (COVERALL-3). (In Press). The journal of infectious diseases Oxford University Press 10.1093/infdis/jiae291 <http://dx.doi.org/10.1093/infdis/jiae291>

Predmety: Adult, Male, 0301 basic medicine, COVID-19 Vaccines, T-Lymphocytes, Immunization, Secondary, 610 Medicine & health, HIV Infections, Antibodies, Viral, Cohort Studies, Immunocompromised Host, 03 medical and health sciences, SARS-CoV-2 vaccine, Bivalent vaccine, Major Article, Humans, Aged, Female, Middle Aged, 2019-nCoV Vaccine mRNA-1273/immunology, Antibodies, Neutralizing/blood, Antibodies, Neutralizing/immunology, Antibodies, Viral/blood, BNT162 Vaccine/immunology, BNT162 Vaccine/administration & dosage, COVID-19/prevention & control, COVID-19/immunology, COVID-19 Vaccines/immunology, COVID-19 Vaccines/administration & dosage, HIV Infections/immunology, HIV Infections/prevention & control, Immunocompromised Host/immunology, SARS-CoV-2/immunology, Spike Glycoprotein, Coronavirus/immunology, Switzerland, T-Lymphocytes/immunology, HIV, SARS-CoV-2, bivalent vaccine, organ transplant, vaccine, BNT162 Vaccine, 0303 health sciences, COVID-19, Organ transplant, Antibodies, Neutralizing, Spike Glycoprotein, Coronavirus, Vaccine, 2019-nCoV Vaccine mRNA-1273

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38848312
https://archive-ouverte.unige.ch/unige:179658
https://doi.org/10.1093/infdis/jiae291
https://serval.unil.ch/resource/serval:BIB_3D75BC1FB104.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_3D75BC1FB104
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_3D75BC1FB1042
https://boris.unibe.ch/197683/

Quantitative assay to analyze neutralization and inhibition of authentic Middle East respiratory syndrome coronavirus

Autori: Helena Müller-Kräuter Jolanda Mezzacapo Michael Klüver a ďalší

Zdroj: Med Microbiol Immunol

Predmety: 0301 basic medicine, 0303 health sciences, Antibodies, Viral/blood [MeSH], Neutralization Tests/methods [MeSH], Middle East Respiratory Syndrome Coronavirus/immunology [MeSH], Coronavirus Infections/diagnosis [MeSH], Antibodies, Neutralizing/blood [MeSH], Humans [MeSH], Neutralization, VNT, Vaccine, Animals [MeSH], Coronavirus Infections/prevention, Antibodies, Neutralizing/immunology [MeSH], Sensitivity and Specificity [MeSH], MNA, Coronavirus Infections/immunology [MeSH], Original Investigation, MERS-CoV, Inhibitory Concentration 50 [MeSH], Middle East respiratory syndrome coronavirus, Antibodies, Viral, Antibodies, Neutralizing, Sensitivity and Specificity, Inhibitory Concentration 50, 03 medical and health sciences, Neutralization Tests, Middle East Respiratory Syndrome Coronavirus, Humans, Animals, Coronavirus Infections

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38722338
https://repository.publisso.de/resource/frl:6504911

CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies

Autori: Jonathan Richard Gérémy Sannier Li Zhu a ďalší

Zdroj: mBio
mBio, Vol 15, Iss 11 (2024)
mBio, vol. 15, no. 11, pp. e0182724

Predmety: Env, CD4-Positive T-Lymphocytes, nnAbs, Antibody-Dependent Cell Cytotoxicity, env Gene Products, Human Immunodeficiency Virus, Down-Regulation, HIV Infections, bNAbs, HIV Antibodies, Microbiology, Antibodies, Neutralizing, QR1-502, Mice, Antibody-Dependent Cell Cytotoxicity/immunology, HIV-1/immunology, HIV-1/genetics, Humans, HIV Antibodies/immunology, CD4-Positive T-Lymphocytes/immunology, CD4-Positive T-Lymphocytes/virology, CD4 Antigens/metabolism, CD4 Antigens/immunology, CD4 Antigens/genetics, HIV Infections/immunology, HIV Infections/virology, env Gene Products, Human Immunodeficiency Virus/immunology, env Gene Products, Human Immunodeficiency Virus/genetics, env Gene Products, Human Immunodeficiency Virus/metabolism, Antibodies, Neutralizing/immunology, Animals, A32, ADCC, HIV-1, RNA-flow fish, hu-mice, CD4 Antigens, Research Article

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39373535
https://doaj.org/article/e5ef3dc6caf5435fa447f314f7bf4a25
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_8B81A83C3D192
https://serval.unil.ch/notice/serval:BIB_8B81A83C3D19
https://serval.unil.ch/resource/serval:BIB_8B81A83C3D19.P001/REF.pdf

Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development

Autori: Hesselman, Maria C Zeeb, Marius Rusert, Peter a ďalší

Zdroj: Cell host & microbe, vol. 33, no. 2, pp. 279-293.e6

Predmety: AIDS Vaccines, elite neutralizers, HIV vaccine, broadly neutralizing antibodies, env Gene Products, Human Immunodeficiency Virus, envelope glycoprotein, HIV Infections, HIV Antibodies, Cross Reactions, HIV Envelope Protein gp120, Antibodies, Neutralizing, Epitopes, HIV-1/immunology, HIV-1/genetics, Humans, Cysteine/genetics, Cysteine/immunology, Cysteine/chemistry, HIV Antibodies/immunology, HIV Infections/immunology, HIV Infections/virology, Antibodies, Neutralizing/immunology, Epitopes/immunology, Epitopes/genetics, env Gene Products, Human Immunodeficiency Virus/immunology, env Gene Products, Human Immunodeficiency Virus/genetics, env Gene Products, Human Immunodeficiency Virus/chemistry, HIV Envelope Protein gp120/immunology, HIV Envelope Protein gp120/genetics, HIV Envelope Protein gp120/chemistry, Env stabilization, V1V2, HIV-1, Cysteine, Immune Evasion

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39909038
https://serval.unil.ch/resource/serval:BIB_1110935E8631.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_1110935E8631
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1110935E86310

Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency

Autori: Lang-Meli J. Fuchs J. Mathe P. a ďalší

Zdroj: J Clin Immunol

Predmety: Adult, Male, 0301 basic medicine, Adolescent, Primary Immunodeficiency Diseases, Antibodies, Viral, Plasma, Young Adult, 03 medical and health sciences, Humans, Child, COVID-19 Serotherapy, Aged, COVID-19, Common variable immunodeficiency, Antibodies, Viral/immunology [MeSH], COVID-19/immunology [MeSH], Aged [MeSH], Plasma/immunology [MeSH], COVID-19/therapy [MeSH], Original Article, Antibodies, Neutralizing/immunology [MeSH], Male [MeSH], SARS-CoV-2/immunology [MeSH], Child [MeSH], Immunization, Passive/methods [MeSH], SARS-CoV-2, Primary immunodeficiencies, Adolescent [MeSH], Female [MeSH], Primary Immunodeficiency Diseases/immunology [MeSH], Adult [MeSH], Antibodies, Monoclonal/immunology [MeSH], Humans [MeSH], Middle Aged [MeSH], Inborn errors of immunity, Virus Shedding/immunology [MeSH], Young Adult [MeSH], Convalescent plasma, Hypogammaglobulinemia, Immunization, Passive, Antibodies, Monoclonal, Middle Aged, Antibodies, Neutralizing, Virus Shedding, 3. Good health, Female, common variable immunodeficiency, convalescent plasma, hypogammaglobulinemia, inborn errors of immunity, primary immunodeficiencies

Popis súboru: application/pdf; pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s10875-021-01193-2.pdf
https://pubmed.ncbi.nlm.nih.gov/34893946
https://repository.publisso.de/resource/frl:6446023

Mechanisms of Neutralizing Anti-drug Antibody Formation and Clinical Relevance on Therapeutic Efficacy of Enzyme Replacement Therapies in Fabry Disease

Autori: Malte Lenders Eva Brand

Zdroj: Drugs

Predmety: Male, 0301 basic medicine, Trihexosylceramides, Review Article, Antibodies, Neutralizing, Recombinant Proteins, Injection Site Reaction, 3. Good health, Isoenzymes, Lysosomal Storage Diseases, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, alpha-Galactosidase, Antibody Formation, Fabry Disease, Humans, Enzyme Replacement Therapy, Pharmacology/Toxicology, Fabry Disease/physiopathology [MeSH], alpha-Galactosidase/adverse effects [MeSH], Enzyme Replacement Therapy/adverse effects [MeSH], Humans [MeSH], alpha-Galactosidase/therapeutic use [MeSH], Enzyme Replacement Therapy/methods [MeSH], Trihexosylceramides/metabolism [MeSH], Isoenzymes/adverse effects [MeSH], Risk Factors [MeSH], Lysosomal Storage Diseases/pathology [MeSH], Injection Site Reaction [MeSH], Recombinant Proteins/adverse effects [MeSH], Recombinant Proteins/therapeutic use [MeSH], Antibodies, Neutralizing/immunology [MeSH], Antibody Formation [MeSH], Male [MeSH], Fabry Disease/drug therapy [MeSH], Isoenzymes/therapeutic use [MeSH], Internal Medicine, Pharmacotherapy

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s40265-021-01621-y.pdf
https://pubmed.ncbi.nlm.nih.gov/34748189
https://www.ncbi.nlm.nih.gov/pubmed/34748189
https://link.springer.com/content/pdf/10.1007/s40265-021-01621-y.pdf
https://pubmed.ncbi.nlm.nih.gov/34748189/
https://link.springer.com/article/10.1007/s40265-021-01621-y
https://paperity.org/p/275572639/mechanisms-of-neutralizing-anti-drug-antibody-formation-and-clinical-relevance-on
https://repository.publisso.de/resource/frl:6465085

Development of Neutralizing Multimeric Nanobody Constructs Directed against IL-13: From Immunization to Lead Optimization: From Immunization to Lead Optimization

Autori: Philippe J-L Y Gevenois Pieter De Pauw Steve Schoonooghe a ďalší

Prispievatelia: Philippe J-L Y Gevenois Pieter De Pauw Steve Schoonooghe a ďalší

Zdroj: The Journal of Immunology. 207:2608-2620

Predmety: 0301 basic medicine, 0303 health sciences, Interleukin-13, Antibody Affinity/immunology, Antibody Affinity, Single-Domain Antibodies/immunology, Sciences bio-médicales et agricoles, Single-Domain Antibodies, Antibodies, Neutralizing/immunology, Antibodies, Neutralizing, 3. Good health, 03 medical and health sciences, Humans, Interleukin-13/antagonists & inhibitors

Popis súboru: 1 full-text file(s): application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/34645688
https://www.ncbi.nlm.nih.gov/pubmed/34645688
https://biblio.vub.ac.be/vubir/(ebe2dc14-7168-42d1-8721-b8ec96a92c9c).html

Sensitivity of two SARS-CoV-2 variants with spike protein mutations to neutralising antibodies

Autori: Stefanie Gruetzner Roman Wölfel Katharina Müller a ďalší

Zdroj: Virus Genes

Predmety: 0301 basic medicine, ddc:610, Original Paper, SARS-CoV-2, Antibodies, Monoclonal, COVID-19, Antibodies, Viral/immunology [MeSH], Mutation [MeSH], COVID-19/immunology [MeSH], COVID-19/virology [MeSH], Antibodies, Monoclonal/therapeutic use [MeSH], Antibodies, Monoclonal/immunology [MeSH], Humans [MeSH], SARS-CoV-2/genetics [MeSH], Antibodies, Neutralizing/therapeutic use [MeSH], Spike Glycoprotein, Coronavirus/genetics [MeSH], Antibodies, Neutralizing/immunology [MeSH], Mutation E484K, SARS-CoV-2/immunology [MeSH], Antibodies, Viral/therapeutic use [MeSH], SARS-CoV-2/chemistry [MeSH], B.1.351, Neutralising antibodies, Immune escape, Variants of concern, Antibodies, Viral, Antibodies, Neutralizing, 3. Good health, 03 medical and health sciences, Mutation, Spike Glycoprotein, Coronavirus, Humans

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s11262-021-01871-8.pdf
https://pubmed.ncbi.nlm.nih.gov/34608598
https://link.springer.com/content/pdf/10.1007/s11262-021-01871-8.pdf
http://europepmc.org/article/MED/34608598
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489549
https://link.springer.com/article/10.1007%2Fs11262-021-01871-8
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/90801
https://nbn-resolving.org/urn:nbn:de:bvb:384-opus4-908019
https://doi.org/10.1007/s11262-021-01871-8
https://repository.publisso.de/resource/frl:6444750