Výsledky vyhľadávania - "Anti-Inflammatory Agents/pharmacology [MeSH]"

β-Citronellol: a potential anti-inflammatory and gastro-protective agent-mechanistic insights into its modulatory effects on COX-II, 5-LOX, eNOS, and ICAM-1 pathways through in vitro, in vivo, in silico, and network pharmacology studies

Autori: Urooj Iqbal Abdul Malik Nabeela Tabassum Sial a ďalší

Zdroj: Inflammopharmacology

Predmety: Male, Arachidonate 5-Lipoxygenase, Nitric Oxide Synthase Type III, Acyclic Monoterpenes, Indomethacin, Anti-Inflammatory Agents, Network Pharmacology, Intercellular Adhesion Molecule-1, Protective Agents, Molecular Docking Simulation/methods [MeSH], Network Pharmacology/methods [MeSH], β-Citronellol, Computer Simulation [MeSH], Stomach Ulcer/drug therapy [MeSH], Gastroprotective, Original Article, Intercellular Adhesion Molecule-1/metabolism [MeSH], Male [MeSH], Nitric Oxide Synthase Type III/metabolism [MeSH], Molecular docking, Acyclic Monoterpenes/pharmacology [MeSH], Stomach Ulcer/prevention, Stomach Ulcer/metabolism [MeSH], Antioxidants/pharmacology [MeSH], Indomethacin/pharmacology [MeSH], Humans [MeSH], Rats [MeSH], Network pharmacology, Animals [MeSH], Rats, Wistar [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], Arachidonate 5-Lipoxygenase/metabolism [MeSH], Anti-inflammatory, Stomach Ulcer/chemically induced [MeSH], Protective Agents/pharmacology [MeSH], Cyclooxygenase 2/metabolism [MeSH], Antioxidants, Rats, Molecular Docking Simulation, Cyclooxygenase 2, Animals, Humans, Computer Simulation, Stomach Ulcer, Rats, Wistar

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39342545
https://repository.publisso.de/resource/frl:6524558

Atheroprotective role of vinpocetine: an old drug with new indication

Autori: Mohammed H. Abu-Alghayth Hayder M. Al-kuraishy Ali I. Al-Gareeb a ďalší

Zdroj: Inflammopharmacology

Predmety: 0301 basic medicine, 0303 health sciences, NF-kappa B, Anti-Inflammatory Agents, Review, Atherosclerosis, Antioxidants, 3. Good health, Oxidative Stress, 03 medical and health sciences, Humans, Animals, Cytokines, Endothelium, Vascular, Antioxidants/pharmacology [MeSH], Endothelial dysfunction, Atherosclerosis/prevention, Humans [MeSH], Cytokines/metabolism [MeSH], Animals [MeSH], Endothelium, Vascular/drug effects [MeSH], Reactive oxygen species, Anti-Inflammatory Agents/pharmacology [MeSH], NF-kappa B/metabolism [MeSH], Vinpocetine, Atherosclerosis/drug therapy [MeSH], Oxidative Stress/drug effects [MeSH], Endothelium, Vascular/metabolism [MeSH], Vinca Alkaloids/pharmacology [MeSH], Atherosclerosis/metabolism [MeSH], Pro-inflammatory cytokines, Vinca Alkaloids

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39141151
https://repository.publisso.de/resource/frl:6495866

Paradoxical effect of anti-inflammatory drugs on IL-6 mRNA expression in patients with PTSD during treatment

Autori: Cosima Rhein Isabella Apelt Franziska Werner a ďalší

Zdroj: J Neural Transm (Vienna)

Predmety: Male, Adult, Therapy outcome, Female [MeSH], Stress Disorders, Post-Traumatic/genetics [MeSH], Stress Disorders, Post-Traumatic/metabolism [MeSH], Adult [MeSH], Interleukin 6, Posttraumatic stress disorder, Humans [MeSH], Prospective Studies [MeSH], Psychotherapy, Middle Aged [MeSH], Stress Disorders, Post-Traumatic/drug therapy [MeSH], Anti-inflammatory drugs, Anti-Inflammatory Agents/pharmacology [MeSH], Male [MeSH], Psychiatry and Preclinical Psychiatric Studies - Original Article, Anti-Inflammatory Agents/administration, Interleukin-6/genetics [MeSH], Depression/drug therapy [MeSH], RNA, Messenger/metabolism [MeSH], Interleukin-6, Depression, Anti-Inflammatory Agents, Middle Aged, Stress Disorders, Post-Traumatic, 03 medical and health sciences, 0302 clinical medicine, Humans, Female, RNA, Messenger, Prospective Studies

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38613673
https://repository.publisso.de/resource/frl:6523051

The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain

Autori: Ohm, Melanie Hosseini, Shirin Lonnemann, Niklas a ďalší

Zdroj: J Neuroinflammation
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-30 (2024)

Predmety: Lipopolysaccharides, Male, LPS, Anti-Inflammatory Agents, Hippocampus, Synaptic plasticity, neuroinflammation, Mice, Neuroinflammation, ddc:570, Animals, Veröffentlichung der TU Braunschweig, RC346-429, ddc:5, Research, Brain, Succinates, Neuroinflammatory Diseases/metabolism [MeSH], Brain/pathology [MeSH], Mice, Inbred C57BL [MeSH], Brain/drug effects [MeSH], Succinates/therapeutic use [MeSH], Microglia, Neuroinflammatory Diseases/chemically induced [MeSH], Neuroinflammatory Diseases/pathology [MeSH], Animals [MeSH], Succinates/pharmacology [MeSH], Lipopolysaccharides/toxicity [MeSH], Brain/immunology [MeSH], Mice [MeSH], Neuroinflammatory Diseases/drug therapy [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], Male [MeSH], Brain/metabolism [MeSH], Anti-Inflammatory Agents/therapeutic use [MeSH], Neuroinflammatory Diseases/immunology [MeSH], 3. Good health, Mice, Inbred C57BL, ddc:57, Neuroinflammatory Diseases, Neurology. Diseases of the nervous system, Publikationsfonds der TU Braunschweig, ScholarlyArticle

Popis súboru: 30 Seiten

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39164713
https://doaj.org/article/c956a3d2c98b40e0bbefddaa43ee01c7
https://repository.publisso.de/resource/frl:6499555
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00078080
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00078080
https://nbn-resolving.org/urn:nbn:de:gbv:084-2024101805576
https://doi.org/10.1186/s12974-024-03188-3
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00056246/s12974-024-03188-3.pdf

Characterization of Novel α-Mangostin and Paeonol Derivatives With Cancer-Selective Cytotoxicity

Autori: Suneetha Nunna Ying-Pei Huang Mahdi Rasa a ďalší

Zdroj: Mol Cancer Ther

Predmety: 0301 basic medicine, Acetophenones, Anti-Inflammatory Agents, Antineoplastic Agents, Cell Proliferation, Colorectal Neoplasms, Humans, Protein Kinase Inhibitors, Xanthones, Acetophenones/therapeutic use [MeSH], Protein Kinase Inhibitors/pharmacology, Anti-Inflammatory Agents/pharmacology, Xanthones/therapeutic use [MeSH], Antineoplastic Agents/pharmacology, Antineoplastic Agents/pharmacology [MeSH], Xanthones/pharmacology [MeSH], Acetophenones/therapeutic use, Acetophenones/pharmacology [MeSH], Colorectal Neoplasms/drug therapy, Xanthones/therapeutic use, Anti-Inflammatory Agents/therapeutic use, Cell Proliferation [MeSH], Protein Kinase Inhibitors/pharmacology [MeSH], Humans [MeSH], Xanthones/pharmacology, Colorectal Neoplasms/drug therapy [MeSH], Protein Kinase Inhibitors/therapeutic use [MeSH], Protein Kinase Inhibitors/therapeutic use, Anti-Inflammatory Agents/pharmacology [MeSH], Anti-Inflammatory Agents/therapeutic use [MeSH], Antineoplastic Agents/therapeutic use [MeSH], Acetophenones/pharmacology, Antineoplastic Agents/therapeutic use, 3. Good health, 03 medical and health sciences, Small Molecule Therapeutics

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/34789561
https://mct.aacrjournals.org/content/molcanther/early/2021/11/19/1535-7163.MCT-20-0787.full.pdf
https://mct.aacrjournals.org/content/early/2021/11/19/1535-7163.MCT-20-0787
https://pubmed.ncbi.nlm.nih.gov/34789561/
https://repository.publisso.de/resource/frl:6475594
https://hdl.handle.net/2318/1858348
https://doi.org/10.1158/1535-7163.MCT-20-0787

Limited Impact of 6-Mercaptopurine on Inflammation-Induced Chemokines Expression Profile in Primary Cultures of Enteric Nervous System

Autori: Kneusels, Jan Kaehler, Meike Cascorbi, Ingolf a ďalší

Prispievatelia: Kneusels, Jan Kaehler, Meike Cascorbi, Ingolf a ďalší

Zdroj: Neurochem Res

Predmety: MESH: Inflammation, 6-Mercaptopurine, Lipopolysaccharides, 0301 basic medicine, MESH: Gene Expression, MESH: Rats, Interleukin-1beta/genetics [MeSH], Tumor Necrosis Factor-alpha/genetics [MeSH], Enteric Nervous System/cytology [MeSH], Inflammation/chemically induced [MeSH], Rats [MeSH], Lipopolysaccharides [MeSH], Animals [MeSH], Gene Expression/drug effects [MeSH], Inflammatory bowel diseases, Neurons/drug effects [MeSH], CXC motif ligand chemokines, Interleukin-1beta/pharmacology [MeSH], Mercaptopurine/pharmacology [MeSH], Mice [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], Original Paper, Cells, Cultured [MeSH], Tumor Necrosis Factor-alpha/metabolism [MeSH], Enteric glial cells, Interleukin-1beta/metabolism [MeSH], Enteric nervous system, Tumor Necrosis Factor-alpha/pharmacology [MeSH], [SDV]Life Sciences [q-bio], Interleukin-1beta, MESH: Neurons, Anti-Inflammatory Agents, Gene Expression, Enteric Nervous System, Mice, 03 medical and health sciences, MESH: Interleukin-1beta, Animals, MESH: Animals, MESH: Mice, Cells, Cultured, Inflammation, Neurons, MESH: Cells, 0303 health sciences, Cultured, MESH: Enteric Nervous System, Mercaptopurine, Tumor Necrosis Factor-alpha, Rats, 3. Good health, [SDV] Life Sciences [q-bio], MESH: Anti-Inflammatory Agents, MESH: Tumor Necrosis Factor-alpha, MESH: Mercaptopurine, MESH: Lipopolysaccharides

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s11064-021-03324-y.pdf
https://pubmed.ncbi.nlm.nih.gov/33864170
https://www.ncbi.nlm.nih.gov/pubmed/33864170
https://link.springer.com/article/10.1007/s11064-021-03324-y
https://europepmc.org/article/PMC/PMC8187225
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187225
https://link.springer.com/content/pdf/10.1007/s11064-021-03324-y.pdf
https://hal.science/hal-04178448v1
https://hal.science/hal-04178448v1/document
https://doi.org/10.1007/s11064-021-03324-y
https://repository.publisso.de/resource/frl:6445958

Anti-inflammatory microenvironment of esophageal adenocarcinomas negatively impacts survival

Autori: Penelope Pelczar Anastasios D. Giannou Nicola Gagliani a ďalší

Zdroj: Cancer Immunol Immunother

Predmety: Male, 0301 basic medicine, 0303 health sciences, Esophageal Neoplasms, Anti-Inflammatory Agents, Adenocarcinoma, Survival Analysis, 3. Good health, Female [MeSH], Humans [MeSH], Survival Analysis [MeSH], Retrospective Studies [MeSH], Original Article, Anti-Inflammatory Agents/pharmacology [MeSH], Survival, Male [MeSH], Anti-Inflammatory Agents/therapeutic use [MeSH], Esophageal Neoplasms/mortality [MeSH], Esophageal Neoplasms/physiopathology [MeSH], Esophageal adenocarcinoma, Barrett's esophagus, Adenocarcinoma/mortality [MeSH], Anti-inflammatory environment, Adenocarcinoma/physiopathology [MeSH], Tumor Microenvironment [MeSH], 03 medical and health sciences, Tumor Microenvironment, Humans, Female, Retrospective Studies

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00262-020-02517-8.pdf
https://pubmed.ncbi.nlm.nih.gov/32100077
https://link.springer.com/content/pdf/10.1007/s00262-020-02517-8.pdf
https://europepmc.org/article/PMC/PMC7230052
https://fis-uke.de/portal/de/publications/antiinflammatory-microenvironment-of-esophageal-adenocarcinomas-negatively-impacts-survival(a8653de8-ba8c-4495-b254-667766ba599a).html
https://pubmed.ncbi.nlm.nih.gov/32100077/
https://www.ncbi.nlm.nih.gov/pubmed/32100077
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230052
https://repository.publisso.de/resource/frl:6470322

Impact of Sodium Butyrate Treatment in LPS-Stimulated Peripheral Blood Mononuclear Cells of Poorly Controlled Type 2 DM

Autori: Wibowo, Heri Harbuwono, Dante S. Tahapary, Dicky L. a ďalší

Zdroj: Frontiers in endocrinology, 12:652942

Predmety: butyrate, Inflammation [MeSH], Diabetes Mellitus, Type 2/drug therapy [MeSH], Interferon-gamma/metabolism [MeSH], peripheral blood mononuclear cells, Cytokines/metabolism [MeSH], Male [MeSH], Tumor Necrosis Factor-alpha/metabolism [MeSH], Leukocytes, Mononuclear/cytology [MeSH], Interleukin-6/metabolism [MeSH], Mononuclear/drug effects [MeSH], Female [MeSH], inflammatory response, Adult [MeSH], Humans [MeSH], Lipopolysaccharides/metabolism [MeSH], Middle Aged [MeSH], Type 2/blood [MeSH], Interleukin-10/metabolism [MeSH], Butyric Acid/pharmacology [MeSH], NF-kappa B p50 Subunit/metabolism [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], Interleukin-13/metabolism [MeSH], Type 2/immunology [MeSH], lipopolysaccharide (LPS), poorly controlled type 2 diabetes mellitus, Lipopolysaccharides/chemistry [MeSH], Endocrinology

Relation: https://repository.publisso.de/resource/frl:6478769; https://doi.org/10.3389/fendo.2021.652942; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358792/

Dostupnosť: https://repository.publisso.de/resource/frl:6478769
https://doi.org/10.3389/fendo.2021.652942
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358792/

Mitigated viral myocarditis in A/J mice by the immunoproteasome inhibitor ONX 0914 depends on inhibition of systemic inflammatory responses in CoxsackievirusB3 infection

Autori: Carl Christoph Goetzke Nadine Althof Hannah Louise Neumaier a ďalší

Zdroj: Basic Res Cardiol

Predmety: Male, 0301 basic medicine, Proteasome Endopeptidase Complex, Anti-Inflammatory Agents, Coxsackievirus Infections, Myeloid Cells/enzymology [MeSH], Coxsackievirus Infections/enzymology [MeSH], Original Contribution, Inflammation/enzymology [MeSH], Myeloid Cells/virology [MeSH], Oligopeptides/pharmacology [MeSH], Host-Pathogen Interactions [MeSH], Myocarditis/immunology [MeSH], Enterovirus B, Human/immunology [MeSH], Myocarditis, Proteasome Inhibitors/pharmacology [MeSH], Myocytes, Cardiac/virology [MeSH], Myocytes, Cardiac/immunology [MeSH], Inflammation/virology [MeSH], Male [MeSH], Proteasome, Inflammation/drug therapy [MeSH], Proteasome Endopeptidase Complex/metabolism [MeSH], Myocarditis/enzymology [MeSH], Myocytes, Cardiac/drug effects [MeSH], Coxsackievirus Infections/drug therapy [MeSH], Disease Models, Animal [MeSH], Myocarditis/drug therapy [MeSH], Inflammation/immunology [MeSH], Myocytes, Cardiac/enzymology [MeSH], Inflammation, Myeloid Cells/immunology [MeSH], Animals [MeSH], Infection, Mice, Knockout [MeSH], Enterovirus B, Human/pathogenicity [MeSH], Myocarditis/virology [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], Myeloid Cells/drug effects [MeSH], Proteolysis [MeSH], Coxsackievirus Infections/immunology [MeSH], Proteasome Endopeptidase Complex/genetics [MeSH], Cytokine, Cells, Cultured [MeSH], Mice, 03 medical and health sciences, Animals, Myeloid Cells, Myocytes, Cardiac, Cells, Cultured, Mice, Knockout, 2. Zero hunger, 0303 health sciences, Enterovirus B, Human, 3. Good health, Disease Models, Animal, Host-Pathogen Interactions, Proteolysis, Integrative Biomedicine [Topic 3], Technology Platforms, Oligopeptides, Proteasome Inhibitors, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00395-021-00848-w.pdf
https://pubmed.ncbi.nlm.nih.gov/33523326
https://publikationen.uni-tuebingen.de/xmlui/handle/10900/118936
https://bibliographie.uni-tuebingen.de/xmlui/handle/10900/118936
https://paperity.org/p/260436421/mitigated-viral-myocarditis-in-a-j-mice-by-the-immunoproteasome-inhibitor-onx-0914
https://link.springer.com/content/pdf/10.1007/s00395-021-00848-w.pdf
https://link.springer.com/article/10.1007/s00395-021-00848-w
https://pubmed.ncbi.nlm.nih.gov/33523326/
http://edoc.mdc-berlin.de/19966/1/19966oa.pdf
https://repository.publisso.de/resource/frl:6450764

The formyl peptide receptor agonist Ac2-26 alleviates neuroinflammation in a mouse model of pneumococcal meningitis

Autori: Eugenia Kipp Nicole Schröder Christian Blume a ďalší

Zdroj: J Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)

Predmety: 0301 basic medicine, Neutrophils, Bacterial meningitis, Anti-Inflammatory Agents, Hippocampus, Annexin A1/pharmacology [MeSH], Receptors, Formyl Peptide/genetics [MeSH], Treatment Outcome [MeSH], Glial cell, Encephalitis/drug therapy [MeSH], Neutrophils/drug effects [MeSH], Animals [MeSH], Meningitis, Pneumococcal/drug therapy [MeSH], Neutrophil Infiltration/drug effects [MeSH], Mice, Knockout [MeSH], Formyl peptide receptor, Mice [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], Innate immunity, Research, Anti-Inflammatory Agents/therapeutic use [MeSH], Peptides/pharmacology [MeSH], Annexin A1/therapeutic use [MeSH], Hippocampus/drug effects [MeSH], Peptides/therapeutic use [MeSH], Annexin A1, Mice, 03 medical and health sciences, Animals, RC346-429, Mice, Knockout, 0303 health sciences, Meningitis, Pneumococcal, Receptors, Formyl Peptide, 3. Good health, Streptococcus pneumoniae, Treatment Outcome, Neutrophil Infiltration, Encephalitis, Neurology. Diseases of the nervous system, Peptides

Prístupová URL adresa: https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-020-02006-w
https://pubmed.ncbi.nlm.nih.gov/33121515
https://doaj.org/article/2b8d3fb8b72d4a9390405b18948b8297
https://pubmed.ncbi.nlm.nih.gov/33121515/
https://www.ncbi.nlm.nih.gov/pubmed/33121515
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-020-02006-w
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596991
https://link.springer.com/article/10.1186/s12974-020-02006-w
https://europepmc.org/article/MED/33121515
https://repository.publisso.de/resource/frl:6464865

The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells

Autori: Pflüger-Müller, Beatrice Oo, James A. Heering, Jan a ďalší

Zdroj: http://lobid.org/resources/99370671625606441#!, 115(3):34.

Predmety: Anandamide, Chemokine CCL2/drug effects [MeSH], Endocannabinoids/metabolism [MeSH], Humans [MeSH], Inflammation, Original Contribution, Muscle, Smooth, Vascular/metabolism [MeSH], Animals [MeSH], Polyunsaturated Alkamides/pharmacology [MeSH], Arachidonic Acids/metabolism [MeSH], Endocannabinoids/pharmacology [MeSH], Mice [MeSH], Anti-Inflammatory Agents/pharmacology [MeSH], HDAC4, NCoR1, CCL2, Arachidonic Acids/pharmacology [MeSH], Vascular/drug effects [MeSH], Signal Transduction/drug effects [MeSH], Polyunsaturated Alkamides/metabolism [MeSH], Chemokine CCL2/biosynthesis [MeSH], Epigenesis, Genetic/drug effects [MeSH]

Relation: https://repository.publisso.de/resource/frl:6466714; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176595/

Dostupnosť: https://repository.publisso.de/resource/frl:6466714
https://doi.org/10.1007/s00395-020-0793-3
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176595/