Search Results - "Annexin A2"

ANXA2 knockdown inhibits oxidative stress and pyroptosis to alleviate epilepsy by suppressing the toll-like receptor (TLR) pathway.

Authors: Wang F Jiang J Xu T et al.

Source: Cellular signalling [Cell Signal] 2025 Dec; Vol. 136, pp. 112140. Date of Electronic Publication: 2025 Sep 18.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

MeSH Terms: Pyroptosis*/genetics , Oxidative Stress* , Annexin A2*/metabolism , Annexin A2*/genetics , Epilepsy*/metabolism , Epilepsy*/genetics , Epilepsy*/pathology , Epilepsy*/chemically induced , Toll-Like Receptors*/metabolism, Animals ; Rats ; Signal Transduction ; Male ; Neurons/metabolism ; Rats, Sprague-Dawley ; Hippocampus/metabolism ; Hippocampus/pathology ; Gene Knockdown Techniques ; Humans

Targeting annexin A2 enhances anti-PD-1 immunotherapy in pancreatic ductal adenocarcinoma by remodeling the tumor immune microenvironment.

Authors: Liu M Wang G Gao J et al.

Source: International immunopharmacology [Int Immunopharmacol] 2025 Nov 14; Vol. 165, pp. 115504. Date of Electronic Publication: 2025 Sep 09.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: Carcinoma, Pancreatic Ductal*/immunology , Carcinoma, Pancreatic Ductal*/drug therapy , Carcinoma, Pancreatic Ductal*/pathology , Carcinoma, Pancreatic Ductal*/therapy , Carcinoma, Pancreatic Ductal*/genetics , Annexin A2*/genetics , Annexin A2*/metabolism , Annexin A2*/antagonists & inhibitors , Pancreatic Neoplasms*/immunology , Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/therapy , Pancreatic Neoplasms*/pathology , Immune Checkpoint Inhibitors*/pharmacology , Immune Checkpoint Inhibitors*/therapeutic use, Animals ; Tumor Microenvironment/immunology ; Tumor Microenvironment/drug effects ; Humans ; Mice ; Cell Line, Tumor ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/immunology ; Immunotherapy/methods ; CD8-Positive T-Lymphocytes/immunology ; Female ; Mice, Inbred C57BL ; Male ; Cell Proliferation

Annexin A2 interferes with complement regulation within the glomerulus.

Authors: Renner B Laskowski J Poppelaars F et al.

Source: The Journal of biological chemistry [J Biol Chem] 2025 Oct; Vol. 301 (10), pp. 110657. Date of Electronic Publication: 2025 Aug 30.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

MeSH Terms: Annexin A2*/metabolism , Annexin A2*/genetics , Annexin A2*/immunology , Kidney Glomerulus*/metabolism , Kidney Glomerulus*/pathology , Kidney Glomerulus*/immunology , Complement Factor H*/metabolism , Complement Factor H*/genetics, Animals ; Mice ; Humans ; Podocytes/metabolism ; Podocytes/pathology ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Mice, Knockout ; Complement Activation ; Mice, Inbred C57BL

ARNTL2 regulated the oncogene c-myc and promoted the progression of esophageal cancer through activatingANXA2transcription .

Authors: Qin Y Ci H Wang Z et al.

Source: Cancer biology & therapy [Cancer Biol Ther] 2025 Dec 31; Vol. 26 (1), pp. 2574544. Date of Electronic Publication: 2025 Nov 16.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8576 (Electronic) Linking ISSN: 15384047 NLM ISO Abbreviation: Cancer Biol Ther Subsets: MEDLINE

MeSH Terms: Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/metabolism , Annexin A2*/genetics , Annexin A2*/metabolism , Proto-Oncogene Proteins c-myc*/genetics , Proto-Oncogene Proteins c-myc*/metabolism, Humans ; Animals ; Mice ; Gene Expression Regulation, Neoplastic ; Disease Progression ; Cell Proliferation ; Epithelial-Mesenchymal Transition ; Mice, Inbred BALB C ; Cell Line, Tumor ; Male ; Female ; Mice, Nude ; Cell Movement ; Promoter Regions, Genetic ; Middle Aged

Tenascin-C from the tissue microenvironment promotes muscle stem cell maintenance and function through Annexin A2.

Authors: Cecchini A Loreti M Kaufman CD et al.

Source: Communications biology [Commun Biol] 2025 Dec 05; Vol. 8 (1), pp. 1709. Date of Electronic Publication: 2025 Dec 05.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

MeSH Terms: Tenascin*/metabolism , Tenascin*/genetics , Annexin A2*/metabolism , Annexin A2*/genetics , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/cytology , Muscle, Skeletal*/physiology , Stem Cells*/metabolism , Stem Cells*/cytology, Animals ; Mice ; Regeneration ; Mice, Knockout ; Muscle Development ; Mice, Inbred C57BL ; Aging

The Novel Direct AR Target Gene Annexin A2 Mediates Androgen-Induced Cellular Senescence in Prostate Cancer Cells.

Authors: Mirzakhani K Heidari Horestani M Kallenbach J et al.

Source: Biochemical genetics [Biochem Genet] 2025 Dec; Vol. 63 (6), pp. 5013-5028. Date of Electronic Publication: 2024 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0126611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4927 (Electronic) Linking ISSN: 00062928 NLM ISO Abbreviation: Biochem Genet Subsets: MEDLINE

MeSH Terms: Cellular Senescence*/drug effects , Cellular Senescence*/genetics , Annexin A2*/genetics , Annexin A2*/metabolism , Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/metabolism , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/drug therapy , Receptors, Androgen*/metabolism , Receptors, Androgen*/genetics , Androgens*/pharmacology, Humans ; Male ; Cell Line, Tumor ; Proto-Oncogene Proteins c-akt/metabolism ; Gene Expression Regulation, Neoplastic/drug effects ; HSP27 Heat-Shock Proteins/metabolism ; HSP27 Heat-Shock Proteins/genetics ; Heat-Shock Proteins ; Molecular Chaperones

Plectin promotes bone formation via phase separation and sequestering annexin A2.

Authors: Zheng K He X Yu Y et al.

Source: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 4), pp. 117403. Date of Electronic Publication: 2025 Oct 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Plectin*/metabolism , Plectin*/pharmacology , Plectin*/genetics , Osteogenesis*/physiology , Osteogenesis*/drug effects , Osteoblasts*/metabolism , Osteoblasts*/drug effects , Annexin A2*/metabolism, Animals ; Mice ; Humans ; Cell Differentiation/physiology ; Cell Differentiation/drug effects ; Mice, Inbred C57BL ; Osteoporosis/metabolism ; Osteoporosis/drug therapy ; Male ; Phase Separation

Isoliquiritigenin inhibits the activation of the ANXA2/STAT3 pathway by down-regulating TAGLN2, thereby alleviating alcoholic fatty liver.

Authors: Fan F Zhu F Jiang C et al.

Source: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 2), pp. 117308. Date of Electronic Publication: 2025 Sep 06.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: STAT3 Transcription Factor*/metabolism , STAT3 Transcription Factor*/antagonists & inhibitors , Chalcones*/pharmacology , Chalcones*/therapeutic use , Annexin A2*/metabolism , Annexin A2*/antagonists & inhibitors , Annexin A2*/genetics , Fatty Liver, Alcoholic*/metabolism , Fatty Liver, Alcoholic*/drug therapy , Microfilament Proteins*/metabolism , Microfilament Proteins*/antagonists & inhibitors , Microfilament Proteins*/genetics, Animals ; Mice ; Male ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Humans ; Mice, Inbred C57BL ; Hep G2 Cells

Calcium oxalate alters lipid profiles and annexin A2 enrichment in membrane fractions of murine inner medullary collecting duct cells.

Authors: Shahzad Z Rafay R Khan S et al.

Source: Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2025 Dec; Vol. 1869 (12), pp. 130868. Date of Electronic Publication: 2025 Oct 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8006 (Electronic) Linking ISSN: 03044165 NLM ISO Abbreviation: Biochim Biophys Acta Gen Subj Subsets: MEDLINE

MeSH Terms: Kidney Tubules, Collecting*/metabolism , Kidney Tubules, Collecting*/drug effects , Kidney Tubules, Collecting*/cytology , Calcium Oxalate*/pharmacology , Annexin A2*/metabolism , Cell Membrane*/metabolism , Cell Membrane*/drug effects, Animals ; Mice ; Phosphatidylserines/metabolism ; Cell Line ; Kidney Medulla/metabolism

Dihydroartemisinin targets ANXA2 to suppress hepatocellular carcinoma angiogenesis through the PI3K/AKT signaling pathway.

Authors: Cao L Wang L Lin J et al.

Source: Tissue & cell [Tissue Cell] 2025 Dec; Vol. 97, pp. 103087. Date of Electronic Publication: 2025 Aug 13.

Publication Type: Journal Article

Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH Terms: Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/blood supply , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/genetics , Liver Neoplasms*/pathology , Liver Neoplasms*/drug therapy , Liver Neoplasms*/blood supply , Liver Neoplasms*/metabolism , Liver Neoplasms*/genetics , Proto-Oncogene Proteins c-akt*/metabolism , Signal Transduction*/drug effects , Phosphatidylinositol 3-Kinases*/metabolism , Annexin A2*/metabolism , Annexin A2*/genetics , Artemisinins*/pharmacology , Neovascularization, Pathologic*/drug therapy , Neovascularization, Pathologic*/pathology, Humans ; Human Umbilical Vein Endothelial Cells ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Angiogenesis

VSIG2 hinders gastric cancer progression by suppressing ANXA2-mediated NF-κB pathway activation.

Authors: Ni Q Wang Y Bian X et al.

Source: Acta biochimica et biophysica Sinica [Acta Biochim Biophys Sin (Shanghai)] 2025 Nov 04; Vol. 57 (11), pp. 1834-1846.

Publication Type: Journal Article

Journal Info: Publisher: China Science Publishing & Media Ltd Country of Publication: China NLM ID: 101206716 Publication Model: Print Cited Medium: Internet ISSN: 1745-7270 (Electronic) Linking ISSN: 16729145 NLM ISO Abbreviation: Acta Biochim Biophys Sin (Shanghai) Subsets: MEDLINE

MeSH Terms: Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/genetics , NF-kappa B*/metabolism , Annexin A2*/metabolism , Annexin A2*/genetics , Signal Transduction*, Humans ; Animals ; Disease Progression ; Mice ; Male ; Female ; Cell Line, Tumor ; Cell Proliferation ; Mice, Nude ; Middle Aged ; Gene Expression Regulation, Neoplastic ; Cell Movement ; Mice, Inbred BALB C ; Prognosis

HSPB1/KDM1 A facilitates ANXA2 expression via hypomethylated DNA promoter to inhibit ferroptosis and enhance gemcitabine resistance in pancreatic cancer.

Authors: Yang L Wang R Zhang L

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Nov; Vol. 398 (11), pp. 15665-15681. Date of Electronic Publication: 2025 May 14.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

MeSH Terms: Ferroptosis*/drug effects , Pancreatic Neoplasms*/drug therapy , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Annexin A2*/genetics , Annexin A2*/metabolism , Deoxycytidine*/analogs & derivatives , Deoxycytidine*/pharmacology , Deoxycytidine*/therapeutic use , Antimetabolites, Antineoplastic*/pharmacology , Heat-Shock Proteins*/genetics , Heat-Shock Proteins*/metabolism , HSP27 Heat-Shock Proteins*/genetics , HSP27 Heat-Shock Proteins*/metabolism, Humans ; Drug Resistance, Neoplasm ; Animals ; Promoter Regions, Genetic ; Gemcitabine ; Cell Line, Tumor ; Mice, Nude ; Molecular Chaperones/genetics ; Mice ; DNA Methylation ; Male ; Mice, Inbred BALB C ; Female ; Gene Expression Regulation, Neoplastic

Annexin A2 facilitates porcine circovirus type 2 infection by mediating viral attachment to host cells and interacting with the capsid protein.

Authors: Jiang Y Lei X Liu W et al.

Source: Veterinary research [Vet Res] 2025 Oct 10; Vol. 56 (1), pp. 191. Date of Electronic Publication: 2025 Oct 10.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9309551 Publication Model: Electronic Cited Medium: Internet ISSN: 1297-9716 (Electronic) Linking ISSN: 09284249 NLM ISO Abbreviation: Vet Res Subsets: MEDLINE

MeSH Terms: Annexin A2*/metabolism , Annexin A2*/genetics , Circovirus*/physiology , Capsid Proteins*/metabolism , Circoviridae Infections*/veterinary , Circoviridae Infections*/virology , Circoviridae Infections*/metabolism , Virus Attachment* , Swine Diseases*/virology, Animals ; Swine ; Cell Line

Serum sFlt-1/PlGF ratio combined with ANXA2 correlates with adverse pregnancy outcomes in women with suspected preeclampsia.

Authors: Chen Y Huang L Zhang J et al.

Source: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2025 Dec; Vol. 38 (1), pp. 2506008. Date of Electronic Publication: 2025 Jul 20.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101136916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4954 (Electronic) Linking ISSN: 14764954 NLM ISO Abbreviation: J Matern Fetal Neonatal Med Subsets: MEDLINE

MeSH Terms: Pre-Eclampsia*/blood , Pre-Eclampsia*/diagnosis , Placenta Growth Factor*/blood , Vascular Endothelial Growth Factor Receptor-1*/blood , Annexin A2*/blood, Humans ; Female ; Pregnancy ; Adult ; Pregnancy Outcome/epidemiology ; Prospective Studies ; Biomarkers/blood ; Infant, Newborn

A ⁶⁸ Ga-/ ¹⁷⁷ Lu-labeled theranostic pair targeting annexin A2 for precision management of breast cancer.

Authors: Yang J Xie Y Zhang L et al.

Source: Bioorganic chemistry [Bioorg Chem] 2025 Nov; Vol. 166, pp. 109149. Date of Electronic Publication: 2025 Oct 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH Terms: Gallium Radioisotopes*/chemistry , Gallium Radioisotopes*/pharmacology , Lutetium*/chemistry , Lutetium*/pharmacology , Annexin A2*/metabolism , Radiopharmaceuticals*/chemistry , Radiopharmaceuticals*/pharmacology , Radiopharmaceuticals*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Breast Neoplasms*/diagnostic imaging, Animals ; Humans ; Mice ; Female ; Tissue Distribution ; Radioisotopes/chemistry ; Theranostic Nanomedicine ; Molecular Structure ; Mice, Inbred BALB C ; Cell Proliferation/drug effects ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Structure-Activity Relationship ; Positron-Emission Tomography ; Drug Screening Assays, Antitumor

ANXA2 in hepatocellular carcinoma: orchestrating tumorigenesis, progression, and therapeutic resistance toward precision targeting.

Authors: Chen J Li J Ran L et al.

Source: Journal of translational medicine [J Transl Med] 2025 Oct 15; Vol. 23 (1), pp. 1104. Date of Electronic Publication: 2025 Oct 15.

Publication Type: Journal Article; Review

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH Terms: Liver Neoplasms*/pathology , Liver Neoplasms*/metabolism , Liver Neoplasms*/therapy , Liver Neoplasms*/genetics , Liver Neoplasms*/drug therapy , Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/therapy , Carcinoma, Hepatocellular*/genetics , Disease Progression* , Annexin A2*/metabolism , Carcinogenesis*/pathology , Carcinogenesis*/metabolism , Drug Resistance, Neoplasm* , Precision Medicine*, Humans ; Animals ; Epithelial-Mesenchymal Transition ; Molecular Targeted Therapy

Multi-omics analysis identifies S100a10/Anxa2 complex within proximal tubule aggravates acute kidney injury through p-Stat3/Spp1 signaling.

Authors: Chen Z Ye L Zhu M et al.

Source: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2025 Oct; Vol. 284, pp. 57-68. Date of Electronic Publication: 2025 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101280339 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1810 (Electronic) Linking ISSN: 18781810 NLM ISO Abbreviation: Transl Res Subsets: MEDLINE

MeSH Terms: Annexin A2*/metabolism , STAT3 Transcription Factor*/metabolism , Acute Kidney Injury*/metabolism , Acute Kidney Injury*/genetics , Acute Kidney Injury*/pathology , Kidney Tubules, Proximal*/metabolism , Kidney Tubules, Proximal*/pathology , S100 Proteins*/metabolism , S100 Proteins*/genetics , Osteopontin*/metabolism, Signal Transduction ; Animals ; Humans ; Male ; Cisplatin ; Mice ; Multiomics

Galangin alleviates vitiligo by targeting ANXA2 degradation in macrophages.

Authors: Wei W Alimujiang A Zhang Z et al.

Source: British journal of pharmacology [Br J Pharmacol] 2025 Oct; Vol. 182 (19), pp. 4647-4667. Date of Electronic Publication: 2025 Jun 17.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

MeSH Terms: Flavonoids*/pharmacology , Flavonoids*/therapeutic use , Vitiligo*/drug therapy , Vitiligo*/metabolism , Vitiligo*/chemically induced , Vitiligo*/pathology , Macrophages*/drug effects , Macrophages*/metabolism , Annexin A2*/metabolism , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/therapeutic use, Animals ; Mice, Inbred C57BL ; Mice ; Hydrogen Peroxide ; Male ; Humans ; Cell Proliferation/drug effects

Pro-inflammatory regulation of EGFR-Annexin A2 synergy by sodium butyrate: An upstream target to reduce articular inflammation and cartilage destruction in rheumatoid arthritis.

Authors: Jayaswamy PK Haridas V Vijaykrishnaraj M et al.

Source: Cytokine [Cytokine] 2025 Oct; Vol. 194, pp. 157008. Date of Electronic Publication: 2025 Aug 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0023 (Electronic) Linking ISSN: 10434666 NLM ISO Abbreviation: Cytokine Subsets: MEDLINE

MeSH Terms: Arthritis, Rheumatoid*/metabolism , Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/pathology , ErbB Receptors*/metabolism , Butyric Acid*/pharmacology , Inflammation*/metabolism , Inflammation*/pathology , Inflammation*/drug therapy , Annexin A2*/metabolism , Cartilage, Articular*/pathology , Cartilage, Articular*/metabolism , Cartilage, Articular*/drug effects, Animals ; Humans ; Mice ; Arthritis, Experimental/metabolism ; Arthritis, Experimental/pathology ; Arthritis, Experimental/drug therapy ; Fibroblasts/metabolism ; Fibroblasts/drug effects ; Mice, Inbred DBA ; Annexin A1/metabolism ; Male ; Synovial Membrane/pathology ; Synovial Membrane/metabolism ; Tumor Necrosis Factor-alpha/metabolism

Downregulation of ANXA2 suppresses trophoblast cell invasion and migration through β-catenin pathway in preeclampsia.

Authors: Mei Z Gong M Lai J et al.

Source: Placenta [Placenta] 2025 Sep; Vol. 169, pp. 60-71. Date of Electronic Publication: 2025 Jul 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8006349 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3102 (Electronic) Linking ISSN: 01434004 NLM ISO Abbreviation: Placenta Subsets: MEDLINE

MeSH Terms: Trophoblasts*/metabolism , Trophoblasts*/physiology , Pre-Eclampsia*/metabolism , Pre-Eclampsia*/pathology , Annexin A2*/metabolism , Annexin A2*/genetics , Cell Movement*/physiology , beta Catenin*/metabolism, Humans ; Female ; Pregnancy ; Down-Regulation ; Adult ; Cell Proliferation ; Wnt Signaling Pathway ; Placenta/metabolism ; Cell Line