Search Results - "Animal models in research"

Experimental models of epilepsy: A comprehensive review of mechanisms, translational relevance, and future directions.

Authors: Jiji, P. J. Rai, Rajalakshmi Kumar, Nayanatara Arun et al.

Source: Veterinary World. Oct2025, Vol. 18 Issue 10, p3041-3050. 10p.

Subjects: Epilepsy, Animal models in research, Investigational therapies, Artificial intelligence, Systems biology, Seizures (Medicine), Ethical problems, Brain imaging

Animal models of autism spectrum disorder: Insights into genetic, structural and environmental models.

Authors: CHIVCHIBASHI-PAVLOVA, DARIYA BRATOEVA, KAMELIYA

Source: Veterinární Medicína. 2025, Vol. 70 Issue 7, p227-241. 15p.

Subjects: Autism spectrum disorders, Animal models in research, Cognition, Behaviorism (Psychology), Neural development, Pathogenesis, Disease risk factors, Molecular genetics

Precision Oncology Strategy and Personalized Medicine for the Treatment of Malignant Peripheral Nerve Sheath Tumor

Authors: Ortega Bertran, Sara

Contributors: University/Department: Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut

Thesis Advisors: Lázaro García, Conxi, Fernández Rodríguez, Juana, Viñals Canals, Francesc

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Ciències de la salut, Ciencias biomédicas, Medical sciences, Sarcoma, Cèl·lules canceroses, Células cancerosas, Cancer cells, Models animals en la investigació, Modelos animales en investigación, Animal models in research, Investigació farmacèutica, Investigación farmacéutica, Pharmaceutical research, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/695626

A long-lasting porcine model of ARDS caused by Pseudomonas aeruginosa and Ventilator-Induced Lung Injury

Authors: Arrieta Ruiz, Marta

Contributors: University/Department: Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut

Thesis Advisors: Torres Martí, Antoni, Rigol Muxart, Montserrat

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Malalties del pulmó, Enfermedades pulmonares, Pulmonary diseases, Respiració artificial, Respiración artificial, Artificial respiration, Pseudomonas, Models animals en la investigació, Modelos animales en investigación, Animal models in research, Ciències de la Salut

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694653

Estudio de nuevas aproximaciones terapéuticas aplicadas a patologías musculoesqueléticas en nuevos modelos animales que imitan la patología humana

Authors: Vidal i Fornells, Laura

Contributors: University/Department: Universitat de Barcelona. Facultat de Farmàcia i Ciències de l'Alimentació

Thesis Advisors: Marotta Baleriola, Mario, Marrero González, Pedro F.

Source: TDX (Tesis Doctorals en Xarxa)

Subject Terms: Medicina esportiva, Medicina deportiva, Sports medicine, Lesions esportives, Lesiones deportivas, Sports injuries, Tendinitis, Models animals en la investigació, Modelos animales en investigación, Animal models in research, Teràpia cel·lular, Terapia celular, Cellular therapy, Ciències de la Salut

Time: 616.7

File Description: application/pdf

Access URL: http://hdl.handle.net/10803/694367

Acoustic complexity of pup isolation calls in Mongolian hamsters: 3-frequency phenomena and chaos.

Authors: Rutovskaya, Marina V Volodin, Ilya A Feoktistova, Natalia Y et al.

Source: Current Zoology. Oct2024, Vol. 70 Issue 5, p559-574. 16p.

Subjects: Autism spectrum disorders, Animal models in research, Body size, Body weight, Frequency spectra

"Addicted" rats? Epistemic challenges in modeling addiction with laboratory animals.

Authors: Athéa, Héloïse^1,2 (AUTHOR) heloise.athea@gustaveroussy.fr

Source: History & Philosophy of the Life Sciences. Dec2025, Vol. 47 Issue 4, p1-20. 20p.

Subject Terms: *ANIMAL models in research, *LABORATORY rats, *SCIENTIFIC apparatus & instruments, *EPISTEMICS, *BEHAVIORAL neuroscience, *MENTAL health, *PHILOSOPHY of science, *ADDICTIONS

Applications and Complementarity of Organ‐Chips and Animal Models in Lung Cancer Driver Gene Research.

Authors: Wang, Lu‐Kai Wu, Tsai‐Jung Tsai, Fu‐Ming

Source: Cell Biology International. Nov2025, p1. 15p. 3 Illustrations.

Subject Terms: *LUNG cancer, *ANIMAL models in research, *RAS oncogenes, *CANCER genes, *EPIDERMAL growth factor receptors, *TRANSLATIONAL research, *ALTERNATIVE toxicity testing, *MICROPHYSIOLOGICAL systems

Beyond Rodents: Alternative Animal Models in Colorectal Cancer Research.

Authors: Xiong, Wei Favier, Solène Wu, Ting et al.

Source: International Journal of Molecular Sciences. Nov2025, Vol. 26 Issue 22, p10874. 23p.

Subject Terms: *COLORECTAL cancer, *ANIMAL models in research, *DROSOPHILA, *CAENORHABDITIS elegans, *DRUG resistance, *LABORATORY zebrafish, *CANCER research

Animal models of methylmalonic acidemia: insights and challenges.

Authors: Shan, Shan Liu, Min Ma, Yue et al.

Source: Orphanet Journal of Rare Diseases. 11/14/2025, Vol. 20 Issue 1, p1-8. 8p.

Subject Terms: *ANIMAL models in research, *INBORN errors of metabolism, *UNIVERSITY research, *MEDICAL innovations, *DISEASE complications, *THERAPEUTICS, *GENETIC disorders, *NEUROLOGIC manifestations of general diseases

Polyserine-mediated targeting of FAF2/UBXD8 ameliorates tau aggregation.

Authors: Van Alstyne, Meaghan Brown, Georgia Nguyen, Vanessa L. et al.

Source: Neuron. Nov2025, Vol. 113 Issue 21, p3601-36361. 32761p.

Subject Terms: *NEURODEGENERATION, *ANIMAL models in research, *GLIOSIS, *PROTEASOMES, *PROTEINS

Study Models for Non-Syndromic Hearing Loss.

Authors: Hoyau, Valentine Leclère, Jean-Christophe Moisan, Stéphanie

Source: Cells (2073-4409). Nov2025, Vol. 14 Issue 21, p1658. 24p.

Subject Terms: *HEARING disorders, *ANIMAL models in research, *CELL culture, *INVESTIGATIONAL therapies, *BIOLOGICAL models, *CELL physiology

Modelling Osteoporosis in Pre-Clinical Research—Challenges, Trends and New Approaches.

Authors: Plank, Johannes Damerau, Alexandra Chacon, Madison Skye et al.

Source: Cells (2073-4409). Nov2025, Vol. 14 Issue 21, p1649. 23p.

Subject Terms: *OSTEOPOROSIS, *ANIMAL models in research, *THERAPEUTICS, *TRANSLATIONAL research, *IN vivo studies, *MICROPHYSIOLOGICAL systems, *BONE diseases

Modeling Glioblastoma for Translation: Strengths and Pitfalls of Preclinical Studies.

Authors: D'Antonio, Concetta Liguori, Giovanna L.

Source: Biology (2079-7737). Nov2025, Vol. 14 Issue 11, p1490. 38p.

Subject Terms: *GLIOBLASTOMA multiforme, *ANIMAL models in research, *THERAPEUTICS, *CELL culture, *SIMULATION methods & models, *TUMOR microenvironment, *TRANSLATIONAL research, *MEDICAL sciences

Replicating human diabetes: insights from a novel animal model.

Authors: Teixidó-Trujillo, Silvia Porrini, Esteban Menéndez-Quintanal, Luis Manuel et al.

Source: American Journal of Physiology: Endocrinology & Metabolism. Nov2025, Vol. 329 Issue 5, p1-14. 14p.

Subject Terms: *TYPE 2 diabetes, *ANIMAL models in research, *OBESITY, *HYPERGLYCEMIA, *ISLANDS of Langerhans, *INSULIN, *PATHOLOGICAL physiology, *TRANSCRIPTION factors

Translatability of Animal Models for Alzheimer's Disease Using a Machine Learning Based Workflow.

Authors: Foster‐Powell, Alex Meno‐Tetang, Guy Rostami‐Hodjegan, Amin et al.

Source: CTS: Clinical & Translational Science. Nov2025, Vol. 18 Issue 11, p1-12. 12p.

Subject Terms: *ALZHEIMER'S disease, *ANIMAL models in research, *DNA microarrays, *MACHINE learning, *PATHOLOGICAL physiology, *TREATMENT failure, *TRANSLATIONAL research

Theme 4 In Vivo Experimental Models.

Authors: Paolantoni, Chiara Campenhoudt, Marine Van Källstig, Emma et al.

Source: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2025 Suppl 2, Vol. 26, p114-127. 14p.

Subject Terms: *AMYOTROPHIC lateral sclerosis, *ANIMAL models in research, *RNA-binding proteins, *GUT microbiota, *PROTEINS, *NEURODEGENERATION, *THERAPEUTICS, *GENETIC mutation

Establishment of disseminated neonatal echovirus 11 infection model in hFcRn transgenic mice.

Authors: Li, Fei Li, Qi Zhao, Xin et al.

Source: Virology Journal. 10/28/2025, Vol. 22 Issue 1, p1-12. 12p.

Subject Terms: *NEONATAL sepsis, *ANIMAL models in research, *VIRAL load, *ECHO viruses, *CYTOKINES, *FC receptors, *HISTOPATHOLOGY, *PATHOGENESIS

Presentation and characterisation of the ALBA micro8 system for targeted hyperthermia in small animal research.

Authors: Groen, J. A. Zweije, R. Sijbrands, J. et al.

Source: Scientific Reports. 10/29/2025, Vol. 15 Issue 1, p1-13. 13p.

Subject Terms: *CANCER research, *ANIMAL models in research, *THERAPEUTICS, *TUMORS, *TEMPERATURE distribution, *THERMOTHERAPY, *ELECTRIC heating, *MEDICAL sciences

Establishing an in vivo large animal model of one-lung ventilation and operative lung trauma.

Authors: Giffin, Catherine Kormish, Jay Hinton, Martha et al.

Source: PLoS ONE. 10/27/2025, Vol. 20 Issue 10, p1-16. 16p.

Subject Terms: *LUNG injuries, *ANIMAL models in research, *PIGLETS, *ARTIFICIAL respiration, *OPERATIVE surgery