Search Results - "Angiotensin II"

Stimulation of angiotensin II type 2 receptor recruit skeletal and cardiac muscle microvasculature in humans.

Authors: Tan WKA Jahn LA Hartline L et al.

Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2025 Nov 01; Vol. 329 (5), pp. E755-E763. Date of Electronic Publication: 2025 Oct 13.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE

MeSH Terms: Receptor, Angiotensin, Type 2*/metabolism , Receptor, Angiotensin, Type 2*/agonists , Muscle, Skeletal*/blood supply , Muscle, Skeletal*/drug effects , Muscle, Skeletal*/metabolism , Angiotensin II*/pharmacology , Microvessels*/drug effects , Microvessels*/metabolism, Humans ; Male ; Adult ; Female ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Benzimidazoles/pharmacology ; Biphenyl Compounds ; Glucose Clamp Technique ; Insulin/pharmacology ; Young Adult ; Tetrazoles/pharmacology ; Myocardium/metabolism ; Hemodynamics/drug effects ; Microcirculation/drug effects ; Brachial Artery/drug effects ; Regional Blood Flow/drug effects ; Receptor, Angiotensin, Type 1

Sodium appetite is enhanced in 5/6 nephrectomized rat by high-sodium diet via increased levels of angiotensin II in the subfornical organ.

Authors: Aoki T Ohashi N Uchiyama Y et al.

Source: Hypertension research : official journal of the Japanese Society of Hypertension [Hypertens Res] 2025 Oct; Vol. 48 (10), pp. 2595-2605. Date of Electronic Publication: 2025 Jul 29.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9307690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1348-4214 (Electronic) Linking ISSN: 09169636 NLM ISO Abbreviation: Hypertens Res Subsets: MEDLINE

MeSH Terms: Angiotensin II*/metabolism , Appetite*/drug effects , Appetite*/physiology , Subfornical Organ*/metabolism , Subfornical Organ*/drug effects , Sodium Chloride, Dietary*/pharmacology , Sodium, Dietary* , Renal Insufficiency, Chronic*/metabolism , Renal Insufficiency, Chronic*/physiopathology, Animals ; Nephrectomy ; Male ; Rats ; Renin-Angiotensin System/drug effects ; Renin-Angiotensin System/physiology ; Kidney/metabolism ; Rats, Sprague-Dawley ; Blood Pressure/drug effects ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Sodium/metabolism

Angiotensin II Type 1 Receptor Blocker Usage Prevents Oxidative Stress and Muscle Dysfunction in HIV.

Authors: Deminice R Cella PS Borsari AL et al.

Source: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2025 Aug; Vol. 39 (4), pp. e70016.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Science Country of Publication: England NLM ID: 8710411 Publication Model: Print Cited Medium: Internet ISSN: 1472-8206 (Electronic) Linking ISSN: 07673981 NLM ISO Abbreviation: Fundam Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Oxidative Stress*/drug effects , Angiotensin II Type 1 Receptor Blockers*/therapeutic use , Angiotensin II Type 1 Receptor Blockers*/pharmacology , Muscle, Skeletal*/drug effects , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/pathology , Muscle, Skeletal*/physiopathology , HIV Infections*/drug therapy , HIV Infections*/complications , HIV Infections*/physiopathology , HIV Infections*/metabolism , Muscular Atrophy*/prevention & control, Humans ; Male ; Female ; Middle Aged ; Adult ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Muscle Strength/drug effects ; Receptor, Angiotensin, Type 1/metabolism ; Angiotensin II/blood

Placental ischemia-upregulated angiotensin II type 1 receptor in hypothalamic paraventricular nucleus contributes to hypertension in rat.

Authors: Issotina Zibrila A Zhou J Wang X et al.

Source: Pflugers Archiv : European journal of physiology [Pflugers Arch] 2024 Nov; Vol. 476 (11), pp. 1677-1691. Date of Electronic Publication: 2024 Aug 31.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 0154720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2013 (Electronic) Linking ISSN: 00316768 NLM ISO Abbreviation: Pflugers Arch Subsets: MEDLINE

MeSH Terms: Paraventricular Hypothalamic Nucleus*/metabolism , Paraventricular Hypothalamic Nucleus*/drug effects , Receptor, Angiotensin, Type 1*/metabolism , Receptor, Angiotensin, Type 1*/genetics , Rats, Sprague-Dawley* , Placenta*/metabolism , Placenta*/drug effects , Losartan*/pharmacology , Angiotensin II*/pharmacology, Animals ; Pregnancy ; Female ; Rats ; Hypertension/metabolism ; Hypertension/physiopathology ; Ischemia/metabolism ; Pre-Eclampsia/metabolism ; Pre-Eclampsia/physiopathology ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Up-Regulation ; Blood Pressure/drug effects

Renin-angiotensin blockade ameliorates the progression of glomerular injury in podocyte-specific Ctcf knockout mice.

Authors: Fujioka K Nagai T Hattori T et al.

Source: Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2024 Dec; Vol. 29 (12), pp. 815-824. Date of Electronic Publication: 2024 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Science Country of Publication: Australia NLM ID: 9615568 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1797 (Electronic) Linking ISSN: 13205358 NLM ISO Abbreviation: Nephrology (Carlton) Subsets: MEDLINE

MeSH Terms: Podocytes*/metabolism , Podocytes*/drug effects , Podocytes*/pathology , Mice, Knockout* , Proteinuria*/metabolism , Proteinuria*/genetics , CCCTC-Binding Factor*/genetics , CCCTC-Binding Factor*/metabolism , Renin-Angiotensin System*/drug effects , Disease Progression* , Angiotensin II Type 1 Receptor Blockers*/pharmacology , Disease Models, Animal*, Animals ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Cells, Cultured ; Angiotensin II ; Phenotype ; Male ; Mice, Inbred C57BL ; Mice ; Kidney Glomerulus/pathology ; Kidney Glomerulus/metabolism ; Kidney Glomerulus/drug effects

A novel angiotensin II type 2 receptor antagonist TDI05 alleviates the peripheral neuropathic pain.

Authors: Mao Q Zeng Y Liang H et al.

Source: Neuroscience letters [Neurosci Lett] 2025 Nov 01; Vol. 867, pp. 138369. Date of Electronic Publication: 2025 Aug 28.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7972 (Electronic) Linking ISSN: 03043940 NLM ISO Abbreviation: Neurosci Lett Subsets: MEDLINE

MeSH Terms: Neuralgia*/drug therapy , Neuralgia*/metabolism , Angiotensin II Type 2 Receptor Blockers*/pharmacology , Angiotensin II Type 2 Receptor Blockers*/therapeutic use , Receptor, Angiotensin, Type 2*/metabolism , Analgesics*/pharmacology , Analgesics*/therapeutic use, Animals ; Mice ; Male ; RAW 264.7 Cells ; Mice, Inbred C57BL ; Macrophages/drug effects ; Macrophages/metabolism ; TRPA1 Cation Channel/metabolism

Real-world Experience of Angiotensin II and Renin Usage in Patients With Distributive Shock:A Single-center Descriptive Study.

Authors: Möller Petrun A Gorenjak M Svenšek F et al.

Source: Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2025 Dec; Vol. 39 (12), pp. 3359-3367. Date of Electronic Publication: 2025 Aug 23.

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 9110208 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8422 (Electronic) Linking ISSN: 10530770 NLM ISO Abbreviation: J Cardiothorac Vasc Anesth Subsets: MEDLINE

MeSH Terms: Angiotensin II*/administration & dosage , Angiotensin II*/therapeutic use , Renin*/administration & dosage , Renin*/blood , Renin*/therapeutic use , Vasoconstrictor Agents*/administration & dosage , Shock*/drug therapy , Shock*/blood , Shock, Septic*/drug therapy , Shock, Septic*/blood, Humans ; Male ; Retrospective Studies ; Female ; Middle Aged ; Aged ; Cohort Studies ; Adult

HSPD1 regulates angiotensin II‑induced atrial fibrillation via the PPAR signaling pathway.

Authors: Zhou Y Zhang L Zhou S et al.

Source: Molecular medicine reports [Mol Med Rep] 2025 Dec; Vol. 32 (6). Date of Electronic Publication: 2025 Sep 26.

Publication Type: Journal Article

Journal Info: Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-3004 (Electronic) Linking ISSN: 17912997 NLM ISO Abbreviation: Mol Med Rep Subsets: MEDLINE

MeSH Terms: Angiotensin II*/metabolism , Angiotensin II*/pharmacology , Atrial Fibrillation*/metabolism , Atrial Fibrillation*/genetics , Atrial Fibrillation*/pathology , Atrial Fibrillation*/chemically induced , Signal Transduction*/drug effects , Heat-Shock Proteins*/genetics , Heat-Shock Proteins*/metabolism , Peroxisome Proliferator-Activated Receptors*/metabolism, Humans ; Protein Interaction Maps ; Molecular Chaperones/metabolism ; Molecular Chaperones/genetics ; Fibroblasts/metabolism ; Cell Movement ; Gene Expression Regulation ; Cell Survival/drug effects ; Cytokines/metabolism ; Chaperonin 60 ; Mitochondrial Proteins

Angiotensin II Activates Yes-Associated Protein (YAP) in Fibroblast Promoting Deep Fascia Remodeling.

Authors: Caroccia B Caputo I Bertoldi G et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 17; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 17.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Fibroblasts*/metabolism , Fibroblasts*/drug effects , Angiotensin II*/pharmacology , Angiotensin II*/metabolism , Adaptor Proteins, Signal Transducing*/metabolism , Fascia*/metabolism , Fascia*/cytology , Fascia*/drug effects , Transcription Factors*/metabolism, Humans ; YAP-Signaling Proteins ; Receptor, Angiotensin, Type 1/metabolism ; Cell Proliferation/drug effects ; Signal Transduction/drug effects ; Cell Movement/drug effects ; Cells, Cultured

Angiotensin II Promotes Progressive Activation of Fibrogenic Periostin-Lineage Cells in Lung and Kidney.

Authors: Ozdemir M Guirao-Abad JP Kasprovic DA et al.

Source: Cells [Cells] 2025 Oct 11; Vol. 14 (20). Date of Electronic Publication: 2025 Oct 11.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Angiotensin II*/pharmacology , Angiotensin II*/metabolism , Kidney*/pathology , Kidney*/metabolism , Kidney*/drug effects , Lung*/pathology , Lung*/metabolism , Lung*/drug effects , Cell Adhesion Molecules*/metabolism , Cell Lineage*/drug effects, Animals ; Fibrosis ; Mice ; Myofibroblasts/metabolism ; Myofibroblasts/drug effects ; Male ; Fibroblasts/metabolism ; Mice, Inbred C57BL ; Periostin

A molecular mechanism for angiotensin II receptor blocker-mediated slit membrane protection: Angiotensin II increases nephrin endocytosis via AT1-receptor-dependent ERK 1/2 activation.

Authors: Königshausen E Zierhut UM Ruetze M et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Sep 15; Vol. 38 (17), pp. e70018.

Publication Type: Journal Article

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH Terms: Endocytosis*/drug effects , Endocytosis*/physiology , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Angiotensin II*/pharmacology , Angiotensin II*/metabolism , Receptor, Angiotensin, Type 1*/metabolism , Receptor, Angiotensin, Type 1*/genetics, Animals ; Humans ; MAP Kinase Signaling System/drug effects ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Mice ; Albuminuria/metabolism ; Podocytes/metabolism ; Podocytes/drug effects ; Mitogen-Activated Protein Kinase 3/metabolism ; Mitogen-Activated Protein Kinase 3/genetics ; Biphenyl Compounds/pharmacology ; Irbesartan/pharmacology ; HEK293 Cells ; beta-Arrestin 2/metabolism ; beta-Arrestin 2/genetics ; Benzimidazoles ; Tetrazoles

Angiotensin II-induced fibrosis is mediated by activation of FGFR1 pathway in renal epithelial cells: Attenuation by chimeric peptide.

Authors: Venkadakrishnan J Bhat A Jadhav KB et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2025 Dec 15; Vol. 1009, pp. 178390. Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH Terms: Angiotensin II*/pharmacology , Receptor, Fibroblast Growth Factor, Type 1*/metabolism , Epithelial Cells*/drug effects , Epithelial Cells*/metabolism , Epithelial Cells*/pathology , Kidney*/pathology , Kidney*/drug effects , Kidney*/metabolism , Peptides*/pharmacology, Fibrosis ; Animals ; Cell Proliferation/drug effects ; Receptor, Angiotensin, Type 1/metabolism ; Signal Transduction/drug effects ; Oxidative Stress/drug effects ; Rats ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Cell Line

Analysis of clinical experience with angiotensin II: A meta-analysis and 4 AI.

Authors: Isern-de-Val Í Antón Juarros S Malingre Gajino M et al.

Source: Medicina intensiva [Med Intensiva (Engl Ed)] 2025 Dec; Vol. 49 (12), pp. 502269. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article; Meta-Analysis; Comparative Study

Journal Info: Publisher: Elsevier España Country of Publication: Spain NLM ID: 101717568 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2173-5727 (Electronic) Linking ISSN: 21735727 NLM ISO Abbreviation: Med Intensiva (Engl Ed) Subsets: MEDLINE

MeSH Terms: Angiotensin II*/therapeutic use , Angiotensin II*/adverse effects , Artificial Intelligence* , Shock*/drug therapy , Shock*/mortality , Vasoconstrictor Agents*/therapeutic use, Humans

Angiotensin II-induced phosphorylation of CHK1 at serine-280 drives cardiac remodelling by direct phosphorylation of JAK1, thus activating JAK1-STAT signalling in murine cardiomyocytes.

Authors: Xu Z Shen Y Luo X et al.

Source: British journal of pharmacology [Br J Pharmacol] 2025 Dec; Vol. 182 (24), pp. 6120-6135. Date of Electronic Publication: 2025 Aug 24.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

MeSH Terms: Angiotensin II*/pharmacology , Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/drug effects , Checkpoint Kinase 1*/metabolism , Checkpoint Kinase 1*/antagonists & inhibitors , Janus Kinase 1*/metabolism , Ventricular Remodeling*/drug effects, Animals ; Phosphorylation/drug effects ; Mice, Inbred C57BL ; Signal Transduction/drug effects ; Mice ; Male ; Rats ; Serine/metabolism ; Cells, Cultured ; STAT Transcription Factors/metabolism

ABI3BP deficiency alleviates Ang II-induced VSMC senescence through the Nrf2 signalling pathway.

Authors: Mao A Tu Q Xie H et al.

Source: Mechanisms of ageing and development [Mech Ageing Dev] 2025 Dec; Vol. 228, pp. 112104. Date of Electronic Publication: 2025 Aug 30.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 0347227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6216 (Electronic) Linking ISSN: 00476374 NLM ISO Abbreviation: Mech Ageing Dev Subsets: MEDLINE

MeSH Terms: NF-E2-Related Factor 2*/metabolism , NF-E2-Related Factor 2*/genetics , Angiotensin II*/pharmacology , Angiotensin II*/metabolism , Muscle, Smooth, Vascular*/metabolism , Muscle, Smooth, Vascular*/pathology , Cellular Senescence*/drug effects , Signal Transduction*/drug effects , Myocytes, Smooth Muscle*/metabolism , Myocytes, Smooth Muscle*/pathology , Carrier Proteins*/genetics , Carrier Proteins*/metabolism , Aging*/metabolism , Aging*/pathology, Animals ; Mice ; Mice, Knockout ; Male

Region-Specific Roles of TGF-β2 and Angiotensin II in Fibrotic and Inflammatory Remodeling of the Optic Nerve Head.

Authors: Oh SE Kim JH Park SE et al.

Source: Cells [Cells] 2025 Nov 20; Vol. 14 (22). Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Transforming Growth Factor beta2*/metabolism , Angiotensin II*/metabolism , Optic Disk*/pathology , Optic Disk*/metabolism , Inflammation*/pathology , Inflammation*/metabolism, Animals ; Humans ; Fibrosis ; Rats ; Male ; Extracellular Matrix/metabolism ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Rats, Sprague-Dawley ; Ocular Hypertension/pathology ; Ocular Hypertension/metabolism

Knocking Out Rap1a Attenuates Cardiac Remodeling and Fibrosis in a Male Murine Model of Angiotensin II-Induced Hypertension.

Authors: Porter CS Brown LT Lacey C et al.

Source: Cells [Cells] 2025 Nov 20; Vol. 14 (22). Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Angiotensin II* , Hypertension*/chemically induced , Hypertension*/physiopathology , Hypertension*/pathology , Hypertension*/genetics , Hypertension*/metabolism , rap1 GTP-Binding Proteins*/metabolism , rap1 GTP-Binding Proteins*/genetics , rap1 GTP-Binding Proteins*/deficiency , Ventricular Remodeling*, Animals ; Male ; Fibrosis ; Mice, Knockout ; Mice ; Disease Models, Animal ; Receptor for Advanced Glycation End Products/metabolism ; Mice, Inbred C57BL ; Myocardium/pathology ; Myocardium/metabolism

Polo-like Kinase 1 Activation Regulates Angiotensin II-Induced Contraction in Pudendal and Small Mesenteric Arteries from Mice.

Authors: Moraes RA Arishe OO Pratt J et al.

Source: Cells [Cells] 2025 Nov 06; Vol. 14 (21). Date of Electronic Publication: 2025 Nov 06.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Angiotensin II*/pharmacology , Protein Serine-Threonine Kinases*/metabolism , Protein Serine-Threonine Kinases*/genetics , Protein Serine-Threonine Kinases*/antagonists & inhibitors , Mesenteric Arteries*/drug effects , Mesenteric Arteries*/physiology , Mesenteric Arteries*/metabolism , Proto-Oncogene Proteins*/metabolism , Proto-Oncogene Proteins*/genetics , Proto-Oncogene Proteins*/antagonists & inhibitors , Muscle Contraction*/drug effects , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics , Cell Cycle Proteins*/antagonists & inhibitors , Vasoconstriction*/drug effects, Animals ; Male ; Mice ; Polo-Like Kinase 1 ; Mice, Inbred C57BL ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Serotonin/pharmacology ; Enzyme Activation/drug effects

Sacubitril/valsartan and quality of life assessed using the EuroQol Five-dimension Three-level questionnaire level sum score (EQ-5D-3L-LSS) in patients with HFrEF and HFmrEF/HFpEF.

Authors: Yang M Henderson AD Anand IS et al.

Source: European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2025 Nov 04; Vol. 11 (7), pp. 574-589.

Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101669491 Publication Model: Print Cited Medium: Internet ISSN: 2055-6845 (Electronic) NLM ISO Abbreviation: Eur Heart J Cardiovasc Pharmacother Subsets: MEDLINE

MeSH Terms: Aminobutyrates*/therapeutic use , Aminobutyrates*/adverse effects , Angiotensin II Type 1 Receptor Blockers*/adverse effects , Angiotensin II Type 1 Receptor Blockers*/therapeutic use , Angiotensin Receptor Antagonists*/therapeutic use , Angiotensin Receptor Antagonists*/adverse effects , Heart Failure*/drug therapy , Heart Failure*/physiopathology , Heart Failure*/mortality , Heart Failure*/diagnosis , Heart Failure*/psychology , Protease Inhibitors*/therapeutic use , Protease Inhibitors*/adverse effects , Quality of Life* , Stroke Volume*/drug effects, Aged ; Female ; Humans ; Male ; Middle Aged ; Biphenyl Compounds ; Drug Combinations ; Neprilysin/antagonists & inhibitors ; Recovery of Function ; Risk Factors ; Surveys and Questionnaires ; Tetrazoles/therapeutic use ; Tetrazoles/adverse effects ; Time Factors ; Treatment Outcome ; Valsartan/therapeutic use ; Valsartan/adverse effects ; Ventricular Function, Left/drug effects

Impact of early in-hospital initiation of sacubitril/valsartan on left ventricular reverse remodelling in acute heart failure.

Authors: Takahashi T Kusunose K Imai T et al.

Source: European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2025 Nov 04; Vol. 11 (7), pp. 565-573.

Publication Type: Clinical Trial, Phase IV; Journal Article; Multicenter Study; Randomized Controlled Trial

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101669491 Publication Model: Print Cited Medium: Internet ISSN: 2055-6845 (Electronic) NLM ISO Abbreviation: Eur Heart J Cardiovasc Pharmacother Subsets: MEDLINE

MeSH Terms: Aminobutyrates*/administration & dosage , Aminobutyrates*/adverse effects , Angiotensin II Type 1 Receptor Blockers*/adverse effects , Angiotensin II Type 1 Receptor Blockers*/administration & dosage , Angiotensin Receptor Antagonists*/administration & dosage , Angiotensin Receptor Antagonists*/adverse effects , Heart Failure*/drug therapy , Heart Failure*/physiopathology , Heart Failure*/diagnostic imaging , Heart Failure*/diagnosis , Tetrazoles*/administration & dosage , Tetrazoles*/adverse effects , Valsartan*/administration & dosage , Valsartan*/adverse effects , Ventricular Function, Left*/drug effects, Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Acute Disease ; Biphenyl Compounds ; Drug Combinations ; Hospitalization ; Recovery of Function ; Stroke Volume/drug effects ; Time Factors ; Treatment Outcome ; Ventricular Remodeling/drug effects