Suchergebnisse - "Angiogenesis"

Recent progress in the exploitation of anti-cancer small molecules targeting angiogenesis.

Autoren: Zheng Y Qiu H Zhang K et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2584811. Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Angiogenesis Inhibitors*/pharmacology , Angiogenesis Inhibitors*/chemistry , Angiogenesis Inhibitors*/chemical synthesis , Neovascularization, Pathologic*/drug therapy , Neovascularization, Pathologic*/metabolism , Neovascularization, Pathologic*/pathology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Small Molecule Libraries*/pharmacology , Small Molecule Libraries*/chemistry , Small Molecule Libraries*/chemical synthesis , Neoplasms*/drug therapy , Neoplasms*/pathology , Neoplasms*/blood supply, Humans ; Structure-Activity Relationship ; Molecular Structure ; Cell Proliferation/drug effects ; Animals ; Apoptosis/drug effects ; Drug Screening Assays, Antitumor ; Angiogenesis

Low-molecular-weight dextran sulfate sodium as novel heparanase inhibitor preventing breast cancer metastasis in mice by inhibiting migration and angiogenesis.

Autoren: Mo Y Song G Fu L et al.

Quelle: Carbohydrate polymers [Carbohydr Polym] 2025 Dec 01; Vol. 369, pp. 124255. Date of Electronic Publication: 2025 Aug 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE

MeSH-Schlagworte: Glucuronidase*/antagonists & inhibitors , Glucuronidase*/metabolism , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Dextran Sulfate*/pharmacology , Dextran Sulfate*/chemistry , Dextran Sulfate*/therapeutic use , Neovascularization, Pathologic*/drug therapy , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Angiogenesis Inhibitors*/pharmacology , Angiogenesis Inhibitors*/chemistry, Animals ; Humans ; Female ; Cell Movement/drug effects ; Mice ; Human Umbilical Vein Endothelial Cells/drug effects ; Cell Line, Tumor ; Molecular Weight ; Mice, Inbred BALB C ; Neoplasm Metastasis/prevention & control ; Epithelial-Mesenchymal Transition/drug effects ; Angiogenesis

Identification of RIPK1 as a novel target for angiogenesis regulation based on ABT-869 conjugated photoaffinity probes.

Autoren: Li Y Liu T Cheng W et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Nov; Vol. 166, pp. 109191. Date of Electronic Publication: 2025 Nov 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Receptor-Interacting Protein Serine-Threonine Kinases*/antagonists & inhibitors , Receptor-Interacting Protein Serine-Threonine Kinases*/metabolism , Photoaffinity Labels*/chemistry , Photoaffinity Labels*/pharmacology , Photoaffinity Labels*/chemical synthesis , Neovascularization, Pathologic*/drug therapy , Neovascularization, Pathologic*/metabolism , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis , Angiogenesis Inhibitors*/pharmacology , Angiogenesis Inhibitors*/chemistry , Angiogenesis Inhibitors*/chemical synthesis , Sulfonamides*/pharmacology , Sulfonamides*/chemistry, Humans ; Molecular Structure ; Structure-Activity Relationship ; Dose-Response Relationship, Drug ; Human Umbilical Vein Endothelial Cells/drug effects ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Vascular Endothelial Growth Factor Receptor-2/antagonists & inhibitors ; Angiogenesis

Discovery and validation of pyrrolopyrimidine-based VEGFR2 inhibitors targeting tumor angiogenesis via structure-based virtual screening, quantum chemical analysis, and in vitro assays.

Autoren: Foudah AI Sharma P Alam A

Quelle: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2025 Oct 28; Vol. 39 (2), pp. 109. Date of Electronic Publication: 2025 Oct 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4951 (Electronic) Linking ISSN: 0920654X NLM ISO Abbreviation: J Comput Aided Mol Des Subsets: MEDLINE

MeSH-Schlagworte: Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-2*/chemistry , Vascular Endothelial Growth Factor Receptor-2*/metabolism , Pyrimidines*/chemistry , Pyrimidines*/pharmacology , Angiogenesis Inhibitors*/chemistry , Angiogenesis Inhibitors*/pharmacology , Pyrroles*/chemistry , Pyrroles*/pharmacology , Neovascularization, Pathologic*/drug therapy , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/pharmacology , Neoplasms*/drug therapy, Humans ; Molecular Docking Simulation ; Human Umbilical Vein Endothelial Cells ; Molecular Dynamics Simulation ; Drug Discovery ; Structure-Activity Relationship ; Angiogenesis

Angiogenesis and thymic epithelial tumors: from preclinical insights to different therapeutic lines and combination strategies.

Autoren: Miliziano D Sciortino C Manglaviti S et al.

Quelle: Cancer treatment reviews [Cancer Treat Rev] 2025 Dec; Vol. 141, pp. 103049. Date of Electronic Publication: 2025 Nov 13.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7502030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1967 (Electronic) Linking ISSN: 03057372 NLM ISO Abbreviation: Cancer Treat Rev Subsets: MEDLINE

MeSH-Schlagworte: Thymus Neoplasms*/drug therapy , Thymus Neoplasms*/blood supply , Thymus Neoplasms*/pathology , Neovascularization, Pathologic*/drug therapy , Angiogenesis Inhibitors*/therapeutic use , Angiogenesis Inhibitors*/administration & dosage , Neoplasms, Glandular and Epithelial*/drug therapy , Neoplasms, Glandular and Epithelial*/blood supply , Neoplasms, Glandular and Epithelial*/pathology , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use, Humans ; Animals ; Angiogenesis

SCR Disease Name: Thymic epithelial tumor

Betulin, an active component from Chinese herb birch bark, suppresses tumor angiogenesis and tumor growth by inhibiting the PAX2/VEGF-A/VEGR2 signaling pathway in non-small cell lung cancer.

Autoren: Li Z Huang M Wang J et al.

Quelle: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Nov 25; Vol. 148, pp. 157445. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE

MeSH-Schlagworte: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/metabolism , Lung Neoplasms*/drug therapy , Lung Neoplasms*/metabolism , Lung Neoplasms*/pathology , Betula*/chemistry , Triterpenes*/pharmacology , Angiogenesis Inhibitors*/pharmacology , Neovascularization, Pathologic*/drug therapy, Animals ; Humans ; Signal Transduction/drug effects ; Plant Bark/chemistry ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Zebrafish ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Mice ; Human Umbilical Vein Endothelial Cells ; Drugs, Chinese Herbal/pharmacology ; Angiogenesis ; Betulinic Acid

MLN4924, neddylation inhibitor suppresses hypoxia induced retinal angiogenesis by targeting Human Antigen R signaling.

Autoren: Mohan SP NareshKumar RN Cheruvu SS et al.

Quelle: Life sciences [Life Sci] 2025 Nov 01; Vol. 380, pp. 123927. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

MeSH-Schlagworte: Cyclopentanes*/pharmacology , Pyrimidines*/pharmacology , Signal Transduction*/drug effects , ELAV-Like Protein 1*/metabolism , Retinal Neovascularization*/drug therapy , Retinal Neovascularization*/metabolism , Angiogenesis Inhibitors*/pharmacology , Hypoxia*, Humans ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Cell Hypoxia/drug effects ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Angiogenesis

Caulerpin suppresses tumor-associated angiogenesis and tumor growth via Hippo signaling in cervical cancer.

Autoren: Yang G Mo Y Rong H et al.

Quelle: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2025 Nov; Vol. 504, pp. 117541. Date of Electronic Publication: 2025 Sep 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Uterine Cervical Neoplasms*/drug therapy , Uterine Cervical Neoplasms*/pathology , Uterine Cervical Neoplasms*/metabolism , Uterine Cervical Neoplasms*/blood supply , Neovascularization, Pathologic*/drug therapy , Protein Serine-Threonine Kinases*/metabolism , Protein Serine-Threonine Kinases*/antagonists & inhibitors , Indoles*/pharmacology , Indoles*/therapeutic use , Angiogenesis Inhibitors*/pharmacology, Humans ; Female ; Animals ; Hippo Signaling Pathway ; Signal Transduction/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects ; Xenograft Model Antitumor Assays ; HeLa Cells ; Cell Proliferation/drug effects ; Mice, Nude ; Mice ; Mice, Inbred BALB C ; Cell Movement/drug effects ; Apoptosis/drug effects ; YAP-Signaling Proteins ; Adaptor Proteins, Signal Transducing/metabolism ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Angiogenesis

Advances in Magnesium Metal and Its Alloys for Promoting Angiogenesis.

Autoren: Huang J Wu J Liu D et al.

Quelle: Journal of biomedical materials research. Part B, Applied biomaterials [J Biomed Mater Res B Appl Biomater] 2025 Nov; Vol. 113 (11), pp. e35671.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101234238 Publication Model: Print Cited Medium: Internet ISSN: 1552-4981 (Electronic) Linking ISSN: 15524973 NLM ISO Abbreviation: J Biomed Mater Res B Appl Biomater Subsets: MEDLINE

MeSH-Schlagworte: Magnesium*/chemistry , Magnesium*/pharmacology , Alloys*/chemistry , Alloys*/pharmacology , Neovascularization, Physiologic*/drug effects , Angiogenesis Inducing Agents*/pharmacology , Angiogenesis Inducing Agents*/chemistry, Humans ; Animals ; Angiogenesis

Angiogenesis Signaling in Retinoblastoma: Prognostic and Therapeutic Applications.

Autoren: Yang E Odell N Dimaras H et al.

Quelle: International ophthalmology clinics [Int Ophthalmol Clin] 2025 Oct 01; Vol. 65 (4), pp. 35-41. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0374731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-9617 (Electronic) Linking ISSN: 00208167 NLM ISO Abbreviation: Int Ophthalmol Clin Subsets: MEDLINE

MeSH-Schlagworte: Retinoblastoma*/metabolism , Retinoblastoma*/drug therapy , Retinal Neoplasms*/metabolism , Retinal Neoplasms*/drug therapy , Angiogenesis Inhibitors*/therapeutic use , Neovascularization, Pathologic*/metabolism , Neovascularization, Pathologic*/drug therapy, Humans ; Prognosis ; Signal Transduction ; Vascular Endothelial Growth Factor A/metabolism ; Angiogenesis

Selenomethionine suppresses lung tumor growth without hepatorenal toxicity in mice via the induction of apoptosis-ferroptosis and angiogenesis inhibition.

Autoren: Liu H Zhang C Zhang L et al.

Quelle: Tissue & cell [Tissue Cell] 2025 Oct; Vol. 96, pp. 102956. Date of Electronic Publication: 2025 May 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH-Schlagworte: Selenomethionine*/pharmacology , Selenomethionine*/therapeutic use , Apoptosis*/drug effects , Neovascularization, Pathologic*/drug therapy , Neovascularization, Pathologic*/pathology , Lung Neoplasms*/pathology , Lung Neoplasms*/drug therapy , Ferroptosis*/drug effects , Carcinoma, Lewis Lung*/pathology , Carcinoma, Lewis Lung*/drug therapy , Angiogenesis Inhibitors*/pharmacology, Animals ; Mice ; Cell Proliferation/drug effects ; Cell Line, Tumor ; Mice, Inbred C57BL ; Angiogenesis

Bruton's tyrosine kinase inhibition suppresses pathological retinal angiogenesis.

Autoren: Chen S Liu Y Zhang Y et al.

Quelle: British journal of pharmacology [Br J Pharmacol] 2025 Oct; Vol. 182 (20), pp. 4944-4967. Date of Electronic Publication: 2024 Oct 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors , Agammaglobulinaemia Tyrosine Kinase*/metabolism , Retinal Neovascularization*/drug therapy , Retinal Neovascularization*/pathology , Retinal Neovascularization*/metabolism , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/therapeutic use , Angiogenesis Inhibitors*/pharmacology, Animals ; Mice, Inbred C57BL ; Mice ; Humans ; Microglia/drug effects ; Microglia/metabolism ; Mice, Knockout ; Male ; Retina/drug effects ; Angiogenesis

Inhibition of ex vivo VEGF-induced angiogenesis by tyrosol and hydroxytyrosol: a quantitative three-dimensional mouse aortic ring model.

Autoren: Cerezo AB Gallardo-Fernandez M Santana-Garrido Á et al.

Quelle: Food & function [Food Funct] 2025 Oct 27; Vol. 16 (21), pp. 8594-8603. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101549033 Publication Model: Electronic Cited Medium: Internet ISSN: 2042-650X (Electronic) Linking ISSN: 20426496 NLM ISO Abbreviation: Food Funct Subsets: MEDLINE

MeSH-Schlagworte: Phenylethyl Alcohol*/analogs & derivatives , Phenylethyl Alcohol*/pharmacology , Aorta*/drug effects , Vascular Endothelial Growth Factor A*/metabolism , Angiogenesis Inhibitors*/pharmacology, Animals ; Mice ; Humans ; Male ; Phosphorylation/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Vascular Endothelial Growth Factor Receptor-2/genetics ; Mice, Inbred C57BL ; Signal Transduction/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Nitric Oxide Synthase Type III/metabolism ; Nitric Oxide Synthase Type III/genetics ; Phospholipase C gamma/metabolism ; Phospholipase C gamma/genetics ; Angiogenesis

Exploring the Efficacy of AZD6738 in Corneal Neovascularization: Autophagy Enhancement and Angiogenesis Inhibition.

Autoren: Wang Q Peng Y Wang S et al.

Quelle: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics [J Ocul Pharmacol Ther] 2025 Oct; Vol. 41 (8), pp. 444-454. Date of Electronic Publication: 2025 Jun 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Ocular Pharmacology And Therapeutics Country of Publication: United States NLM ID: 9511091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7732 (Electronic) Linking ISSN: 10807683 NLM ISO Abbreviation: J Ocul Pharmacol Ther Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/drug effects , Corneal Neovascularization*/drug therapy , Corneal Neovascularization*/metabolism , Corneal Neovascularization*/pathology , Angiogenesis Inhibitors*/pharmacology , Pyrimidines*/pharmacology, Animals ; Rats, Sprague-Dawley ; Rats ; Humans ; Human Umbilical Vein Endothelial Cells/drug effects ; Cell Survival/drug effects ; Vascular Endothelial Growth Factor A/metabolism ; Cell Movement/drug effects ; Male ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Angiogenesis

Chamuangone purified from Garcinia cowa inhibits inflammation, angiogenesis, epithelial-mesenchymal transition, and metastasis in breast cancer.

Autoren: Rahman AU Khan NU Basit A et al.

Quelle: Journal of the science of food and agriculture [J Sci Food Agric] 2026 Jan 15; Vol. 106 (1), pp. 469-481. Date of Electronic Publication: 2025 Sep 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0010 (Electronic) Linking ISSN: 00225142 NLM ISO Abbreviation: J Sci Food Agric Subsets: MEDLINE

MeSH-Schlagworte: Garcinia*/chemistry , Epithelial-Mesenchymal Transition*/drug effects , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Breast Neoplasms*/physiopathology , Lung Neoplasms*/secondary , Lung Neoplasms*/prevention & control , Lung Neoplasms*/drug therapy , Antineoplastic Agents, Phytogenic*/isolation & purification , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/therapeutic use , Antineoplastic Agents, Phytogenic*/administration & dosage , Antineoplastic Agents, Phytogenic*/chemistry , Neovascularization, Pathologic*/drug therapy , Plant Extracts*/isolation & purification , Plant Extracts*/administration & dosage , Plant Extracts*/chemistry , Plant Extracts*/pharmacology , Plant Extracts*/therapeutic use , Angiogenesis Inhibitors*/isolation & purification , Angiogenesis Inhibitors*/administration & dosage , Angiogenesis Inhibitors*/therapeutic use , Angiogenesis Inhibitors*/pharmacology, Animals ; Female ; Humans ; Mice ; Apoptosis/drug effects ; Mice, Inbred BALB C ; Cell Proliferation/drug effects ; Plant Leaves/chemistry ; MCF-7 Cells ; Cell Line, Tumor ; Inflammation/drug therapy ; Neoplasm Metastasis ; Angiogenesis

Network pharmacology and molecular docking reveal the multi-target mechanisms of Paeoniae Radix Rubra in functional angiogenesis: Synergistic regulation of ADAM10-NOTCH and VEGFR2-PI3K/AKT signaling.

Autoren: Zhang R Hu R Wang Y et al.

Quelle: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jan 30; Vol. 355 (Pt A), pp. 120532. Date of Electronic Publication: 2025 Sep 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Paeonia*/chemistry , Neovascularization, Physiologic*/drug effects , Angiogenesis Inducing Agents*/pharmacology , Drugs, Chinese Herbal*/pharmacology, Animals ; Molecular Docking Simulation ; Humans ; Proto-Oncogene Proteins c-akt/metabolism ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Signal Transduction/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects ; Receptors, Notch/metabolism ; Network Pharmacology ; Mice ; Phosphatidylinositol 3-Kinases/metabolism ; ADAM10 Protein/metabolism ; Cell Proliferation/drug effects ; Cell Movement/drug effects ; Male ; Mice, Inbred C57BL ; Amyloid Precursor Protein Secretases/metabolism ; Hindlimb/blood supply ; Ischemia/drug therapy ; Plant Roots ; Angiogenesis ; Plant Extracts

Decoding Gujin Luyan Xuming decoction: How ancient wisdom meets modern science in promoting angiogenesis to ameliorate cerebral infarction.

Autoren: Cai Y Zhang M He Q et al.

Quelle: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jan 30; Vol. 355 (Pt A), pp. 120652. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

MeSH-Schlagworte: Drugs, Chinese Herbal*/pharmacology , Drugs, Chinese Herbal*/therapeutic use , Drugs, Chinese Herbal*/chemistry , Cerebral Infarction*/drug therapy , Cerebral Infarction*/metabolism , Neovascularization, Physiologic*/drug effects , Angiogenesis Inducing Agents*/pharmacology, Animals ; Molecular Docking Simulation ; Male ; Humans ; Mice ; Human Umbilical Vein Endothelial Cells/drug effects ; Mice, Inbred C57BL ; Rats, Sprague-Dawley ; Network Pharmacology ; Angiogenesis

Effect of Precipitated Extracellular Marennine on Angiogenesis and Tumour Cell Proliferation.

Autoren: Fodil M Muñoz-Garcia J Benali AK et al.

Quelle: Marine drugs [Mar Drugs] 2025 Sep 19; Vol. 23 (9). Date of Electronic Publication: 2025 Sep 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-3397 (Electronic) Linking ISSN: 16603397 NLM ISO Abbreviation: Mar Drugs Subsets: MEDLINE

MeSH-Schlagworte: Cell Proliferation*/drug effects , Neovascularization, Pathologic*/drug therapy , Angiogenesis Inhibitors*/pharmacology , Angiogenesis Inhibitors*/isolation & purification , Diatoms*/chemistry , Neoplasms*/drug therapy , Neoplasms*/pathology, Humans ; Cell Line, Tumor ; Apoptosis/drug effects ; Cell Movement/drug effects ; Animals ; Angiogenesis

Synthesis and evaluation of sulfonamide-chalcone hybrid compounds as inhibitors of VEGFR1/VEGFR2-mediated angiogenesis.

Autoren: Barlak N Sanli F Celik S et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Sep; Vol. 164, pp. 108903. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-2*/metabolism , Angiogenesis Inhibitors*/pharmacology , Angiogenesis Inhibitors*/chemical synthesis , Angiogenesis Inhibitors*/chemistry , Vascular Endothelial Growth Factor Receptor-1*/antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-1*/metabolism , Sulfonamides*/chemistry , Sulfonamides*/pharmacology , Neovascularization, Pathologic*/drug therapy , Neovascularization, Pathologic*/metabolism , Chalcone*/chemistry , Chalcone*/pharmacology , Chalcones*/chemistry , Chalcones*/pharmacology , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry, Humans ; Cell Proliferation/drug effects ; Structure-Activity Relationship ; Human Umbilical Vein Endothelial Cells/drug effects ; Molecular Docking Simulation ; Molecular Structure ; Dose-Response Relationship, Drug ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Angiogenesis

Polysaccharide isolated from Dahlia root tubers affects the proliferation of HUVECs and promotes angiogenesis in zebrafish.

Autoren: Zhang X Wang Y Zhang Z et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Sep; Vol. 321 (Pt 3), pp. 146464. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Polysaccharides*/pharmacology , Polysaccharides*/chemistry , Polysaccharides*/isolation & purification , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/cytology , Neovascularization, Physiologic*/drug effects , Plant Roots*/chemistry , Plant Tubers*/chemistry , Liliaceae*/chemistry , Angiogenesis Inducing Agents*/pharmacology , Angiogenesis Inducing Agents*/chemistry , Angiogenesis Inducing Agents*/isolation & purification, Animals ; Zebrafish ; Humans ; Cell Proliferation/drug effects ; Cell Movement/drug effects ; Molecular Docking Simulation ; Cell Survival/drug effects ; Angiogenesis