Suchergebnisse - "Anemia, Sickle Cell"

The right patient, the right treatment: tailoring sickle cell disease care.

Autoren: Alan S Desai P

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 585-591.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/genetics , Anemia, Sickle Cell*/epidemiology , Precision Medicine*, Humans ; Adult ; Pain Management ; Female

Sickle cell disease: managing thromboembolism.

Autoren: Babu K Wun T

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 279-284.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/blood , Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/drug therapy , Venous Thromboembolism*/prevention & control , Venous Thromboembolism*/etiology , Venous Thromboembolism*/drug therapy , Thromboembolism*/prevention & control, Humans ; Female ; Pregnancy ; Pregnancy Complications, Hematologic ; Factor Xa Inhibitors/therapeutic use

Proactive management to improve outcomes of high-risk pregnancy in people with sickle cell disease.

Autoren: Obadina MA Pecker LH

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 511-522.

Publikationsart: Journal Article; Review; Case Reports

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/complications , Pregnancy Complications, Hematologic*/therapy, Humans ; Female ; Pregnancy ; Adult ; Erythrocyte Transfusion ; Blood Transfusion

Optimizing the right time to start sickle cell therapies.

Autoren: Martin OY Jacob SA

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 577-584.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/genetics , Hydroxyurea*/therapeutic use , Genetic Therapy* , Hematopoietic Stem Cell Transplantation*, Humans ; Antibodies, Monoclonal, Humanized/therapeutic use ; Glutamine/therapeutic use ; Benzaldehydes ; Pyrazines ; Pyrazoles

Optimizing the "right" patient selection for treatment for sickle cell disease.

Autoren: Colombatti R Reggiani G

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 571-576.

Publikationsart: Journal Article; Case Reports; Review

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/genetics , Patient Selection*, Humans ; Male ; Female ; Hydroxyurea/therapeutic use ; Adult ; Hematopoietic Stem Cell Transplantation

Impact of a comprehensive sickle cell disease care programme on community knowledge among Indian tribal populations: a multicentric study.

Autoren: Sharma Y Bhat D Sridevi P et al.

Quelle: Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2025 Dec 05; Vol. 119 (12), pp. 1324-1334.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 7506129 Publication Model: Print Cited Medium: Internet ISSN: 1878-3503 (Electronic) Linking ISSN: 00359203 NLM ISO Abbreviation: Trans R Soc Trop Med Hyg Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/prevention & control , Anemia, Sickle Cell*/epidemiology , Anemia, Sickle Cell*/ethnology , Anemia, Sickle Cell*/diagnosis , Health Knowledge, Attitudes, Practice* , Community Health Services*/organization & administration, Humans ; Male ; India/epidemiology ; Female ; Adult ; Adolescent ; Young Adult ; Middle Aged ; Health Education ; Program Evaluation ; Child

Motivators and barriers affecting decisions to participate in sickle cell disease clinical trials in the global Learning and Insights into Sickle Cell Trial Experiences (LISTEN) Survey: global and regional findings.

Autoren: Mahlangu J Colombatti R James J et al.

Quelle: The Lancet. Haematology [Lancet Haematol] 2025 Dec; Vol. 12 (12), pp. e966-e977.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101643584 Publication Model: Print Cited Medium: Internet ISSN: 2352-3026 (Electronic) Linking ISSN: 23523026 NLM ISO Abbreviation: Lancet Haematol Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/psychology , Anemia, Sickle Cell*/epidemiology , Clinical Trials as Topic* , Motivation* , Patient Participation*/psychology , Decision Making*, Humans ; Male ; Female ; Adult ; Surveys and Questionnaires ; Middle Aged ; Young Adult ; Adolescent ; Patient Selection

Adherence, treatment utilization, clinical and economic outcomes of patients with sickle cell disease with recurrent vaso-occlusive crises treated with recently approved chronic therapies in the US.

Autoren: Udeze C Jerry M Evans K et al.

Quelle: Journal of comparative effectiveness research [J Comp Eff Res] 2025 Dec; Vol. 14 (12), pp. e240232. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Becaris Publishing Country of Publication: England NLM ID: 101577308 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-6313 (Electronic) Linking ISSN: 20426305 NLM ISO Abbreviation: J Comp Eff Res Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/drug therapy , Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/economics , Patient Acceptance of Health Care*/statistics & numerical data , Antisickling Agents*/therapeutic use , Antisickling Agents*/economics, Humans ; Female ; Male ; Retrospective Studies ; Adult ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Monoclonal, Humanized/economics ; United States ; Young Adult ; Adolescent ; Middle Aged ; Recurrence ; Health Care Costs/statistics & numerical data ; Medication Adherence ; Vaso-Occlusive Crises

Challenges in Trials in Sickle Cell Disease: Thromboprophylaxis in Sickle Cell Disease With Central Venous Catheters (THIS) Pilot Study.

Autoren: Abdulrehman J Forté S Tomlinson G et al.

Quelle: Journal of clinical apheresis [J Clin Apher] 2025 Dec; Vol. 40 (6), pp. e70072.

Publikationsart: Journal Article; Randomized Controlled Trial; Multicenter Study

Info zur Zeitschrift: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8216305 Publication Model: Print Cited Medium: Internet ISSN: 1098-1101 (Electronic) Linking ISSN: 07332459 NLM ISO Abbreviation: J Clin Apher Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/therapy , Central Venous Catheters*/adverse effects , Venous Thromboembolism*/prevention & control , Venous Thromboembolism*/etiology , Rivaroxaban*/therapeutic use, Humans ; Pilot Projects ; Adult ; Male ; Female ; Double-Blind Method ; Middle Aged ; Catheterization, Central Venous/adverse effects ; Young Adult

Postpartum Tubal Sterilization in Sickle Cell Disease in the 2012-2019 National Inpatient Sample.

Autoren: Luo A Gemmill A Scott JL et al.

Quelle: Journal of women's health (2002) [J Womens Health (Larchmt)] 2025 Dec; Vol. 34 (12), pp. 1558-1568. Date of Electronic Publication: 2025 Jul 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101159262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-843X (Electronic) Linking ISSN: 15409996 NLM ISO Abbreviation: J Womens Health (Larchmt) Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/epidemiology , Anemia, Sickle Cell*/complications , Sterilization, Tubal*/statistics & numerical data , Postpartum Period*, Humans ; Female ; Cross-Sectional Studies ; Adult ; United States/epidemiology ; Pregnancy ; Inpatients/statistics & numerical data ; Black or African American/statistics & numerical data ; Young Adult ; Adolescent ; White

You only work with what you know: Healthcare providers' experiences using non-pharmacological interventions in managing sickle cell crisis pain in adolescents.

Autoren: Ibitoye BM Garrett B Ranger M et al.

Quelle: The journal of pain [J Pain] 2025 Dec; Vol. 37, pp. 105551. Date of Electronic Publication: 2025 Sep 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Churchill Livingstone Country of Publication: United States NLM ID: 100898657 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-8447 (Electronic) Linking ISSN: 15265900 NLM ISO Abbreviation: J Pain Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/therapy , Pain Management*/methods , Health Personnel*/psychology , Attitude of Health Personnel* , Health Knowledge, Attitudes, Practice* , Pain*/etiology, Humans ; Adolescent ; Male ; Female ; Nigeria ; Adult ; Young Adult

Risk of cancer in patients with thalassemia and sickle cell disease: a systematic review.

Autoren: Merolle L Ghirotto L Schiroli D et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2522967. Date of Electronic Publication: 2025 Jun 22.

Publikationsart: Systematic Review; Journal Article; Review

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/epidemiology , Anemia, Sickle Cell*/therapy , Thalassemia*/complications , Thalassemia*/epidemiology , Thalassemia*/therapy , Neoplasms*/epidemiology , Neoplasms*/etiology, Humans ; Risk Factors ; Incidence ; Male ; Female ; Blood Transfusion

Targeting PIEZO1-TMEM16F Coupling to Mitigate Sickle Cell Disease Complications.

Autoren: Liang P Wan YS Shan KZ et al.

Quelle: American journal of hematology [Am J Hematol] 2025 Dec; Vol. 100 (12), pp. 2261-2275. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/metabolism , Anemia, Sickle Cell*/drug therapy , Anemia, Sickle Cell*/blood , Anemia, Sickle Cell*/pathology , Anoctamins*/metabolism , Anoctamins*/genetics , Phospholipid Transfer Proteins*/metabolism , Phospholipid Transfer Proteins*/genetics , Ion Channels*/metabolism , Ion Channels*/antagonists & inhibitors , Ion Channels*/genetics, Humans ; Phosphatidylserines/metabolism ; Erythrocytes, Abnormal/metabolism ; Erythrocytes, Abnormal/pathology ; Calcium/metabolism ; Mechanotransduction, Cellular/drug effects ; Erythrocytes/metabolism

A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs.

Autoren: Conway AJ Rosanwo TO Williamson TE et al.

Quelle: Experimental hematology [Exp Hematol] 2025 Dec; Vol. 152, pp. 105264. Date of Electronic Publication: 2025 Sep 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/pathology , Anemia, Sickle Cell*/metabolism , Anemia, Sickle Cell*/genetics , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/pathology , Induced Pluripotent Stem Cells*/cytology , Cell Differentiation* , Erythrocytes*/metabolism , Erythrocytes*/pathology , Models, Biological*, Humans ; beta-Globins/genetics

Lower rates of maternal morbidities among pregnant women suffering from sickle cell disease who are exposed to hydroxyurea, a retrospective study from tribal area of Western India.

Autoren: Desai G Balar H Dave K et al.

Quelle: Expert review of hematology [Expert Rev Hematol] 2025 Dec; Vol. 18 (12), pp. 1099-1105. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101485942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4094 (Electronic) Linking ISSN: 17474094 NLM ISO Abbreviation: Expert Rev Hematol Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/drug therapy , Anemia, Sickle Cell*/ethnology , Pregnancy Complications*/chemically induced , Pregnancy Complications*/epidemiology , Pregnancy Complications*/ethnology , Pregnancy Outcome*/epidemiology , Pregnancy Outcome*/ethnology , Hydroxyurea*/adverse effects , Hydroxyurea*/therapeutic use , Antisickling Agents*/adverse effects , Antisickling Agents*/therapeutic use, Retrospective Studies ; India/epidemiology ; India/ethnology ; Humans ; Female ; Pregnancy ; Young Adult ; Adult ; Case-Control Studies ; Rural Population/statistics & numerical data ; Indigenous Peoples/statistics & numerical data ; Congenital Abnormalities/epidemiology ; Congenital Abnormalities/ethnology ; Congenital Abnormalities/etiology ; Infant, Newborn

Sickle cell mice exhibit elevated plasma bilirubin and altered intracranial cerebral blood velocities that are exacerbated by hypoxia-reoxygenation.

Autoren: Nunez FJ Mohieldin AM Pan AY et al.

Quelle: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2025 Dec; Vol. 45 (12), pp. 2329-2341. Date of Electronic Publication: 2025 May 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/blood , Anemia, Sickle Cell*/physiopathology , Bilirubin*/blood , Cerebrovascular Circulation*/physiology , Hypoxia*/physiopathology , Hypoxia*/blood, Animals ; Mice ; Mice, Transgenic ; Blood Flow Velocity ; Male ; Middle Cerebral Artery/physiopathology ; Middle Cerebral Artery/diagnostic imaging ; Disease Models, Animal

Musculoskeletal manifestations of sickle cell disease: an imaging perspective.

Autoren: Sato VN Moriwaki TL Tsuji LK et al.

Quelle: Skeletal radiology [Skeletal Radiol] 2025 Dec; Vol. 54 (12), pp. 2607-2623. Date of Electronic Publication: 2025 Jun 21.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7701953 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2161 (Electronic) Linking ISSN: 03642348 NLM ISO Abbreviation: Skeletal Radiol Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/diagnostic imaging , Musculoskeletal Diseases*/diagnostic imaging , Musculoskeletal Diseases*/etiology , Magnetic Resonance Imaging*/methods, Humans ; Diagnosis, Differential

Mitochondrial retention and autophagy dysregulation drive oxidative stress in sickle cell disease erythrocytes.

Autoren: Ramasamy J Punathil Kannan PK Dhavamani S et al.

Quelle: Experimental hematology [Exp Hematol] 2025 Dec; Vol. 152, pp. 105269. Date of Electronic Publication: 2025 Oct 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/pathology , Anemia, Sickle Cell*/blood , Anemia, Sickle Cell*/metabolism , Anemia, Sickle Cell*/genetics , Oxidative Stress* , Autophagy* , Mitochondria*/metabolism , Mitochondria*/pathology , Erythrocytes*/metabolism , Erythrocytes*/pathology, Humans ; Male ; Female ; Adult ; Reactive Oxygen Species/metabolism

A prime editing strategy to rewrite the γ-globin promoters and reactivate fetal hemoglobin for sickle cell disease.

Autoren: Chalumeau A Bou Dames M Fontana L et al.

Quelle: Blood [Blood] 2025 Nov 27; Vol. 146 (22), pp. 2641-2655.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/genetics , Anemia, Sickle Cell*/therapy , Fetal Hemoglobin*/genetics , Fetal Hemoglobin*/metabolism , gamma-Globins*/genetics , Gene Editing*/methods , Promoter Regions, Genetic*, Humans ; Hematopoietic Stem Cells/metabolism ; Mutation

Silent struggles: Assessing physical and psychosocial burdens among caregivers of children with sickle cell disease in western Sudan-A cross-sectional study.

Autoren: Abdallah W Abbas W Elsharif SAM et al.

Quelle: PloS one [PLoS One] 2025 Nov 25; Vol. 20 (11), pp. e0336469. Date of Electronic Publication: 2025 Nov 25 (Print Publication: 2025).

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Anemia, Sickle Cell*/psychology , Anemia, Sickle Cell*/epidemiology , Anemia, Sickle Cell*/therapy , Caregivers*/psychology , Cost of Illness* , Stress, Psychological*/epidemiology, Humans ; Female ; Cross-Sectional Studies ; Male ; Sudan/epidemiology ; Adult ; Child ; Young Adult ; Adolescent ; Middle Aged ; Child, Preschool