Suchergebnisse - "Administration"

Intranasal cocaine self-administration in male mice.

Autoren: Erickson KR Quan Y Farahbakhsh ZZ et al.

Quelle: Nature communications [Nat Commun] 2025 Dec 05; Vol. 16 (1), pp. 10916. Date of Electronic Publication: 2025 Dec 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Cocaine*/administration & dosage , Cocaine*/blood , Self Administration*/methods , Cocaine-Related Disorders*, Animals ; Male ; Administration, Intranasal ; Mice ; Mice, Inbred C57BL ; Behavior, Animal/drug effects ; Disease Models, Animal ; Dose-Response Relationship, Drug

Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality.

Autoren: Haidara FC Adubra L Abdou M et al.

Quelle: The New England journal of medicine [N Engl J Med] 2025 Oct 16; Vol. 393 (15), pp. 1498-1508.

Publikationsart: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/administration & dosage , Anti-Bacterial Agents*/adverse effects , Azithromycin*/administration & dosage , Azithromycin*/adverse effects , Infant Mortality* , Mass Drug Administration*/adverse effects , Mass Drug Administration*/methods , Mass Drug Administration*/statistics & numerical data , Child Mortality*, Child, Preschool ; Female ; Humans ; Infant ; Male ; Intention to Treat Analysis ; Mali/epidemiology ; Drug Administration Schedule ; Double-Blind Method ; Follow-Up Studies ; Treatment Outcome

Evaluating the reinforcing properties of oxycodone and oxymorphone using intravenous drug self-administration in male rats.

Autoren: Rashvand M Funk D Fletcher PJ et al.

Quelle: Neuropharmacology [Neuropharmacology] 2025 Dec 15; Vol. 281, pp. 110698. Date of Electronic Publication: 2025 Sep 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

MeSH-Schlagworte: Oxycodone*/administration & dosage , Oxycodone*/pharmacology , Oxymorphone*/administration & dosage , Oxymorphone*/pharmacology , Analgesics, Opioid*/administration & dosage , Reinforcement, Psychology*, Animals ; Male ; Self Administration ; Rats ; Dose-Response Relationship, Drug ; Rats, Wistar ; Conditioning, Operant/drug effects ; Reinforcement Schedule ; Administration, Intravenous ; Extinction, Psychological/drug effects

Signal Detection of Drug-Drug Interactions Between Topical Vitamin D3 Analogs and Oral Thiazide Diuretics in Hypercalcemia: Analysis of the Japanese Drug Event Report Database.

Autoren: Inoue A Kondo Y Tsuruhashi S et al.

Quelle: The Journal of dermatology [J Dermatol] 2025 Oct; Vol. 52 (10), pp. 1593-1597. Date of Electronic Publication: 2025 Aug 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7600545 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1346-8138 (Electronic) Linking ISSN: 03852407 NLM ISO Abbreviation: J Dermatol Subsets: MEDLINE

MeSH-Schlagworte: Cholecalciferol*/adverse effects , Cholecalciferol*/analogs & derivatives , Cholecalciferol*/administration & dosage , Hypercalcemia*/chemically induced , Hypercalcemia*/epidemiology , Sodium Chloride Symporter Inhibitors*/adverse effects , Sodium Chloride Symporter Inhibitors*/administration & dosage, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Administration, Oral ; Administration, Topical ; Adverse Drug Reaction Reporting Systems/statistics & numerical data ; Databases, Factual ; Drug Interactions ; Japan/epidemiology ; Risk Factors

Topical versus oral metronidazole for post-haemorrhoidectomy pain: A systematic review and meta-analysis of randomized controlled trials.

Autoren: Pompeu BF Garcia GL Barone GL et al.

Quelle: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland [Colorectal Dis] 2025 Dec; Vol. 27 (12), pp. e70321.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis; Comparative Study; Review

Info zur Zeitschrift: Publisher: Blackwell Science Ltd Country of Publication: England NLM ID: 100883611 Publication Model: Print Cited Medium: Internet ISSN: 1463-1318 (Electronic) Linking ISSN: 14628910 NLM ISO Abbreviation: Colorectal Dis Subsets: MEDLINE

MeSH-Schlagworte: Metronidazole*/administration & dosage , Pain, Postoperative*/drug therapy , Pain, Postoperative*/etiology , Hemorrhoidectomy*/adverse effects , Analgesics*/administration & dosage, Humans ; Randomized Controlled Trials as Topic ; Administration, Topical ; Administration, Oral ; Treatment Outcome ; Male ; Female ; Pain Measurement ; Middle Aged ; Adult

The efficacy and safety of diluted oral phosphate enema versus intravenous sodium glycerophosphate in the treatment of hypophosphatemia in intensive care unit patients - A non-inferiority trial.

Autoren: Najdi H Sayed R Mettawi AS et al.

Quelle: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2025 Dec; Vol. 70, pp. 692-700. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article; Randomized Controlled Trial; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101654592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4577 (Electronic) Linking ISSN: 24054577 NLM ISO Abbreviation: Clin Nutr ESPEN Subsets: MEDLINE

MeSH-Schlagworte: Hypophosphatemia*/drug therapy , Phosphates*/administration & dosage , Phosphates*/adverse effects , Glycerophosphates*/administration & dosage , Glycerophosphates*/adverse effects , Enema*/methods, Humans ; Male ; Female ; Middle Aged ; Prospective Studies ; Administration, Oral ; Intensive Care Units ; Administration, Intravenous ; Aged ; Treatment Outcome ; Adult ; Critical Illness/therapy

The impact of a best practice advisory for shifting to oral medications: A quality improvement project.

Autoren: Linfield RY Moskatel LS Carlton S et al.

Quelle: Journal of hospital medicine [J Hosp Med] 2025 Dec; Vol. 20 (12), pp. 1377-1382. Date of Electronic Publication: 2025 Jul 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: United States NLM ID: 101271025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-5606 (Electronic) Linking ISSN: 15535592 NLM ISO Abbreviation: J Hosp Med Subsets: MEDLINE

MeSH-Schlagworte: Quality Improvement* , Practice Patterns, Physicians'* , Practice Guidelines as Topic*/standards , Anti-Infective Agents*/administration & dosage , Anti-Infective Agents*/economics , Anti-Bacterial Agents*/administration & dosage , Anti-Bacterial Agents*/economics, Humans ; Administration, Oral ; Prospective Studies ; Administration, Intravenous

Changes in menopause-specific quality of life between women with transdermal estradiol versus oral estrogens: results of a randomized controlled trial.

Autoren: Tang R Fan Y Ruan X et al.

Quelle: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2025 Dec; Vol. 41 (1), pp. 2484213. Date of Electronic Publication: 2025 Apr 01.

Publikationsart: Journal Article; Randomized Controlled Trial; Comparative Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8807913 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-0766 (Electronic) Linking ISSN: 09513590 NLM ISO Abbreviation: Gynecol Endocrinol Subsets: MEDLINE

MeSH-Schlagworte: Estradiol*/administration & dosage , Estradiol*/analogs & derivatives , Quality of Life* , Menopause*/drug effects , Menopause*/psychology , Estrogen Replacement Therapy*/methods , Estrogens*/administration & dosage, Humans ; Female ; Middle Aged ; Administration, Cutaneous ; Adult ; Administration, Oral ; Treatment Outcome

Preferences between three options for androgen deprivation therapy: a focus group study.

Autoren: Rush HL Merrick S Marshall J et al.

Quelle: BJU international [BJU Int] 2025 Dec; Vol. 136 (6), pp. 1037-1047. Date of Electronic Publication: 2025 Jul 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: England NLM ID: 100886721 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-410X (Electronic) Linking ISSN: 14644096 NLM ISO Abbreviation: BJU Int Subsets: MEDLINE

MeSH-Schlagworte: Prostatic Neoplasms*/drug therapy , Patient Preference* , Androgen Antagonists*/therapeutic use , Androgen Antagonists*/administration & dosage , Gonadotropin-Releasing Hormone*/agonists , Gonadotropin-Releasing Hormone*/antagonists & inhibitors , Estradiol*/administration & dosage, Humans ; Male ; Aged ; Middle Aged ; Focus Groups ; Administration, Cutaneous ; Administration, Oral ; Aged, 80 and over

A Single- and Multiple-Dose Study to Characterize the Pharmacokinetics and Safety of Dotinurad in Healthy Chinese Adults.

Autoren: Liu Y Chen Q Sun H et al.

Quelle: Clinical drug investigation [Clin Drug Investig] 2025 Dec; Vol. 45 (12), pp. 957-966. Date of Electronic Publication: 2025 Oct 19.

Publikationsart: Journal Article; Clinical Trial, Phase I

Info zur Zeitschrift: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9504817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1918 (Electronic) Linking ISSN: 11732563 NLM ISO Abbreviation: Clin Drug Investig Subsets: MEDLINE

MeSH-Schlagworte: Triazoles*/pharmacokinetics , Triazoles*/adverse effects , Triazoles*/administration & dosage , Uricosuric Agents*/pharmacokinetics , Uricosuric Agents*/adverse effects , Uricosuric Agents*/administration & dosage, Adolescent ; Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Administration, Oral ; China ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Healthy Volunteers ; East Asian People ; Benzothiazoles

Capacity and cost benefits of subcutaneous versus intravenous pertuzumab/trastuzumab: The EASE-SC study.

Autoren: Zietse M Hu J van Staveren ER et al.

Quelle: Breast (Edinburgh, Scotland) [Breast] 2025 Dec; Vol. 84, pp. 104573. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article; Comparative Study; Observational Study; Multicenter Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9213011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3080 (Electronic) Linking ISSN: 09609776 NLM ISO Abbreviation: Breast Subsets: MEDLINE

MeSH-Schlagworte: Trastuzumab*/administration & dosage , Trastuzumab*/economics , Antibodies, Monoclonal, Humanized*/administration & dosage , Antibodies, Monoclonal, Humanized*/economics , Breast Neoplasms*/drug therapy , Breast Neoplasms*/economics , Antineoplastic Combined Chemotherapy Protocols*/economics , Antineoplastic Combined Chemotherapy Protocols*/administration & dosage, Humans ; Female ; Cost-Benefit Analysis ; Injections, Subcutaneous/economics ; Netherlands ; Administration, Intravenous/economics ; Middle Aged ; Infusions, Intravenous/economics ; Receptor, ErbB-2 ; Adult

Exposure-response analysis of oral and intravenous imatinib in critically ill patients with COVID-19 acute respiratory distress syndrome.

Autoren: Said MM Braam AM Duijvelaar E et al.

Quelle: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2025 Dec 01; Vol. 215, pp. 107332. Date of Electronic Publication: 2025 Oct 17.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

MeSH-Schlagworte: Imatinib Mesylate*/administration & dosage , Imatinib Mesylate*/pharmacokinetics , Imatinib Mesylate*/therapeutic use , COVID-19*/complications , Respiratory Distress Syndrome*/drug therapy , COVID-19 Drug Treatment* , Protein Kinase Inhibitors*/pharmacokinetics , Protein Kinase Inhibitors*/administration & dosage, Humans ; Critical Illness ; Male ; Middle Aged ; Female ; Aged ; Administration, Oral ; Administration, Intravenous ; SARS-CoV-2 ; Adult

Perioperative Antimicrobial Strategies in Inflatable Penile Prosthesis Surgery: Associations Between Antifungals, Oral Antibiotics, and Intravenous Antibiotic Duration, and Infection Outcomes.

Autoren: Abou Chawareb E Hammad MAM Azad B et al.

Quelle: The Journal of urology [J Urol] 2025 Dec; Vol. 214 (6), pp. 642-653. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 0376374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3792 (Electronic) Linking ISSN: 00225347 NLM ISO Abbreviation: J Urol Subsets: MEDLINE

MeSH-Schlagworte: Penile Prosthesis*/adverse effects , Anti-Bacterial Agents*/administration & dosage , Antifungal Agents*/administration & dosage , Antifungal Agents*/therapeutic use , Antibiotic Prophylaxis*/methods , Prosthesis-Related Infections*/prevention & control , Prosthesis-Related Infections*/epidemiology , Penile Implantation*/adverse effects , Penile Implantation*/methods , Perioperative Care*/methods, Humans ; Male ; Retrospective Studies ; Middle Aged ; Administration, Oral ; Aged ; Administration, Intravenous ; Risk Factors ; Treatment Outcome ; Reoperation

Zanamivir exposure in healthy rats and rats with acute lung injury.

Autoren: Klouček A Šmardová J Sklenárová M et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2534523. Date of Electronic Publication: 2025 Jul 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Zanamivir*/pharmacokinetics , Zanamivir*/administration & dosage , Acute Lung Injury*/drug therapy , Acute Lung Injury*/chemically induced , Acute Lung Injury*/metabolism , Antiviral Agents*/pharmacokinetics , Antiviral Agents*/administration & dosage, Animals ; Male ; Rats, Wistar ; Rats ; Bronchoalveolar Lavage Fluid/chemistry ; Administration, Inhalation ; Lipopolysaccharides ; Lung/metabolism ; Administration, Intravenous ; Disease Models, Animal ; Tandem Mass Spectrometry

Efficacy of oral isotretinoin monotherapy compared to combination isotretinoin and topical clascoterone for severe acne vulgaris: a multi-center retrospective study.

Autoren: Choi U Xiong G Metko D et al.

Quelle: The Journal of dermatological treatment [J Dermatolog Treat] 2025 Dec; Vol. 36 (1), pp. 2525287. Date of Electronic Publication: 2025 Jul 11.

Publikationsart: Journal Article; Multicenter Study; Comparative Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-1753 (Electronic) Linking ISSN: 09546634 NLM ISO Abbreviation: J Dermatolog Treat Subsets: MEDLINE

MeSH-Schlagworte: Isotretinoin*/administration & dosage , Isotretinoin*/adverse effects , Acne Vulgaris*/drug therapy , Acne Vulgaris*/diagnosis , Dermatologic Agents*/administration & dosage , Dermatologic Agents*/adverse effects , Cortodoxone*/administration & dosage , Cortodoxone*/analogs & derivatives , Cortodoxone*/adverse effects , Androgen Antagonists*/administration & dosage , Androgen Antagonists*/adverse effects, Humans ; Retrospective Studies ; Male ; Female ; Administration, Oral ; Treatment Outcome ; Adult ; Drug Therapy, Combination/methods ; Young Adult ; Severity of Illness Index ; Adolescent ; Administration, Cutaneous ; Quality of Life ; Propionates

Daily Mosnodenvir as Dengue Prophylaxis in a Controlled Human Infection Model.

Autoren: Durbin AP Van Wesenbeeck L Pierce KK et al.

Quelle: The New England journal of medicine [N Engl J Med] 2025 Nov 27; Vol. 393 (21), pp. 2107-2118.

Publikationsart: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

MeSH-Schlagworte: Antiviral Agents*/administration & dosage , Antiviral Agents*/adverse effects , Antiviral Agents*/pharmacokinetics , Dengue*/blood , Dengue*/drug therapy , Dengue*/prevention & control , Dengue*/virology , Dengue Virus*/genetics , Dengue Virus*/immunology , Dengue Virus*/isolation & purification , Drugs, Investigational*/administration & dosage , Drugs, Investigational*/adverse effects , Drugs, Investigational*/pharmacokinetics, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Administration, Oral ; Antibodies, Viral/blood ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drug Administration Schedule ; RNA, Viral/blood ; Viral Load/drug effects ; Treatment Outcome

Early vs. late initiation of long-acting basal insulin during IV insulin in pediatric diabetic ketoacidosis: a GRADE-assessed systematic review and meta-analysis.

Autoren: Shah A Jamal A Qadri M et al.

Quelle: European journal of pediatrics [Eur J Pediatr] 2025 Nov 26; Vol. 184 (12), pp. 797. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis; Review

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1076 (Electronic) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE

MeSH-Schlagworte: Diabetic Ketoacidosis*/drug therapy , Hypoglycemic Agents*/administration & dosage , Insulin, Long-Acting*/administration & dosage, Humans ; Child ; Administration, Intravenous ; Adolescent ; Drug Administration Schedule ; Length of Stay ; Time Factors ; Treatment Outcome

Short-term Abrocitinib Combined with Medicated Topical Therapy Provides Rapid Improvement in Pruritus in Elderly Patients with Moderate-to-severe Atopic Dermatitis: A Retrospective, Observational Real-world Study.

Autoren: Yu Y Chen Y Zhang Y et al.

Quelle: Acta dermato-venereologica [Acta Derm Venereol] 2025 Nov 19; Vol. 105, pp. adv44210. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: MJS Publishing Country of Publication: Sweden NLM ID: 0370310 Publication Model: Electronic Cited Medium: Internet ISSN: 1651-2057 (Electronic) Linking ISSN: 00015555 NLM ISO Abbreviation: Acta Derm Venereol Subsets: MEDLINE

MeSH-Schlagworte: Pruritus*/drug therapy , Pruritus*/diagnosis , Pruritus*/etiology , Dermatitis, Atopic*/drug therapy , Dermatitis, Atopic*/diagnosis , Dermatitis, Atopic*/complications , Pyrimidines*/administration & dosage , Pyrimidines*/adverse effects , Sulfonamides*/administration & dosage , Sulfonamides*/adverse effects , Antipruritics*/administration & dosage , Antipruritics*/adverse effects , Protein Kinase Inhibitors*/administration & dosage , Protein Kinase Inhibitors*/adverse effects , Janus Kinase Inhibitors*/administration & dosage , Janus Kinase Inhibitors*/adverse effects, Humans ; Male ; Female ; Aged ; Retrospective Studies ; Treatment Outcome ; Severity of Illness Index ; Time Factors ; Administration, Cutaneous ; Aged, 80 and over ; Drug Therapy, Combination ; Administration, Oral ; Age Factors ; Drug Administration Schedule

Use of intravenous magnesium sulfate in addition to standard first-line treatment with inhaled/nebulised short-acting beta 2 agonist and systemic steroids in the management of acute asthma exacerbations in children: a systematic review and meta-analyses of randomised controlled trials.

Autoren: Hamud AA Mudawi K Powell C et al.

Quelle: Archives of disease in childhood [Arch Dis Child] 2025 Nov 19; Vol. 110 (12), pp. 955-961. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis

Info zur Zeitschrift: Publisher: BMJ Pub. Group [etc.] Country of Publication: England NLM ID: 0372434 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-2044 (Electronic) Linking ISSN: 00039888 NLM ISO Abbreviation: Arch Dis Child Subsets: MEDLINE

MeSH-Schlagworte: Magnesium Sulfate*/administration & dosage , Magnesium Sulfate*/therapeutic use , Magnesium Sulfate*/adverse effects , Asthma*/drug therapy , Adrenergic beta-2 Receptor Agonists*/administration & dosage , Adrenergic beta-2 Receptor Agonists*/therapeutic use , Anti-Asthmatic Agents*/administration & dosage, Humans ; Child ; Randomized Controlled Trials as Topic ; Administration, Inhalation ; Administration, Intravenous ; Length of Stay/statistics & numerical data ; Hospitalization/statistics & numerical data

Efficacy and safety of apremilast in paediatric patients with moderate-to-severe plaque psoriasis: 52-week results from the SPROUT randomized controlled trial.

Autoren: Paller AS Fiorillo L Becker E et al.

Quelle: The British journal of dermatology [Br J Dermatol] 2025 Nov 18; Vol. 193 (6), pp. 1120-1127.

Publikationsart: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE

MeSH-Schlagworte: Psoriasis*/drug therapy , Psoriasis*/diagnosis , Thalidomide*/analogs & derivatives , Thalidomide*/adverse effects , Thalidomide*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Phosphodiesterase 4 Inhibitors*/administration & dosage , Phosphodiesterase 4 Inhibitors*/adverse effects, Humans ; Child ; Male ; Female ; Adolescent ; Double-Blind Method ; Treatment Outcome ; Severity of Illness Index ; Administration, Oral ; Dose-Response Relationship, Drug ; Drug Administration Schedule