Výsledky vyhľadávania - "Adenosine Monophosphate analogs & derivatives"

SARS-CoV-2 RNA and Nucleocapsid Antigen Are Blood Biomarkers Associated With Severe Disease Outcomes That Improve in Response to Remdesivir

Autori: Kanal Singh Kevin Rubenstein Viviane Callier a ďalší

Prispievatelia: Kanal Singh Kevin Rubenstein Viviane Callier a ďalší

Zdroj: Singh, K, Rubenstein, K, Callier, V, Shaw-Saliba, K, Rupert, A, Dewar, R, Laverdure, S, Highbarger, H, Lallemand, P, Huang, M-L, Jerome, K R, Sampoleo, R, Mills, M G, Greninger, A L, Juneja, K, Porter, D, Benson, C A, Dempsey, W, El Sahly, H M, Focht, C, Jilg, N, Paules, C I, Rapaka, R R, Uyeki, T M, Lane, H C, Beigel, J, Dodd, L E, Adaptive COVID-19 Treatment Trial (ACTT-1) Study Group Members & Nielsen, H 2024, 'SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir', The Journal of Infectious Diseases, vol. 230, no. 3, jiae198, pp. 624-634. https://doi.org/10.1093/infdis/jiae198
The Journal of Infectious Diseases, vol 230, iss 3
Singh, K, Rubenstein, K, Callier, V, Shaw-Saliba, K, Rupert, A, Dewar, R, Laverdure, S, Highbarger, H, Lallemand, P, Huang, M-L, Jerome, K R, Sampoleo, R, Mills, M G, Greninger, A L, Juneja, K, Porter, D, Benson, C A, Dempsey, W, El Sahly, H M, Focht, C, Jilg, N, Paules, C I, Rapaka, R R, Uyeki, T M, Lane, H C, Beigel, J, Dodd, L E & Adaptive COVID-19 Treatment Trial (ACTT-1) Study Group Members 2024, 'SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir', The Journal of Infectious Diseases, vol. 230, no. 3, pp. 624-634. https://doi.org/10.1093/infdis/jiae198

Predmety: Male, Adult, 0301 basic medicine, COVID-19/blood, remdesivir, antiviral efficacy, Antiviral Agents, Adenosine Monophosphate/analogs & derivatives, Coronavirus Nucleocapsid Proteins/immunology, SARS-CoV-2/immunology, 03 medical and health sciences, 0302 clinical medicine, Humans, Coronavirus Nucleocapsid Proteins, Viral, RNA, Viral/blood, Antigens, Antigens, Viral, Aged, Antiviral Agents/therapeutic use, Alanine, SARS-CoV-2, COVID-19, clinical trial, Alanine/analogs & derivatives, antiviral efficacy, clinical trial, COVID-19, remdesivir, SARS-CoV-2, Middle Aged, Viral Load, Adenosine Monophosphate, COVID-19 Drug Treatment, 3. Good health, Antigens, Viral/blood, Treatment Outcome, RNA, RNA, Viral, Female, Biomarkers/blood, Biomarkers

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38657001
https://vbn.aau.dk/da/publications/848d0595-5d78-4048-abfa-86e65c031503
https://doi.org/10.1093/infdis/jiae198
http://www.scopus.com/inward/record.url?scp=85204819223&partnerID=8YFLogxK
https://vbn.aau.dk/ws/files/705491966/Singh_et_al._2024_._SARS-CoV-2_RNA_and_nucleocapsid_antigen_are_blood_biomarkers_associated_with_severe_disease_outcomes_that_improve_in_response_to_remdesivir.pdf
https://escholarship.org/content/qt2hf3r271/qt2hf3r271.pdf
https://escholarship.org/uc/item/2hf3r271

Specific adverse outcomes associated with selective serotonin reuptake inhibitors use in COVID-19 patients might be potentiated by remdesivir use

Autori: Ivan Papic Petra Bistrovic Ivan Krecak a ďalší

Zdroj: Journal of Psychopharmacology. 38:395-403

Predmety: Selective Serotonin Reuptake Inhibitors / adverse effects, Alanine, SARS-CoV-2, COVID-19, remdesivir, Adenosine Monophosphate / analogs & derivatives, Adenosine Monophosphate, COVID-19 Drug Treatment, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Alanine / analogs & derivatives, depression, SSRI, Humans, Selective Serotonin Reuptake Inhibitors, Retrospective Studies

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38481078
https://journals.sagepub.com/doi/10.1177/02698811241237868
https://doi.org/10.1177/02698811241237868
https://urn.nsk.hr/urn:nbn:hr:105:413758
https://doi.org/10.1177/02698811241237868

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results

Autori: Pan H. Peto R. Henao-Restrepo A. -M. a ďalší

Prispievatelia: Pan H. Peto R. Henao-Restrepo A. -M. a ďalší

Zdroj: N Engl J Med
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
The New England journal of medicine, Vol. 384, no.6, p. 497-511 (2021)
2021, 'Repurposed Antiviral Drugs for Covid-19-Interim WHO Solidarity Trial Results', New England Journal of Medicine. https://doi.org/10.1056/NEJMoa2023184
Pan, Hongchao; Peto, Richard; Henao-Restrepo, Ana-Maria; Preziosi, Marie-Pierre; Sathiyamoorthy, Vasee; Abdool Karim, Quarraisha; Alejandria, Marissa M; Hernández García, César; Kieny, Marie-Paule; Malekzadeh, Reza; Murthy, Srinivas; Reddy, K Srinath; Roses Periago, Mirta; Abi Hanna, Pierre; Ader, Florence; Al-Bader, Abdullah M; Alhasawi, Almonther; Allum, Emma; Alotaibi, Athari; Alvarez-Moreno, Carlos A; ... (2021). Repurposed Antiviral Drugs for Covid-19-Interim WHO Solidarity Trial Results. New England journal of medicine NEJM, 384(6), pp. 497-511. Massachusetts Medical Society MMS 10.1056/NEJMoa2023184 <http://dx.doi.org/10.1056/NEJMoa2023184>
The new england journal o f medicine

Predmety: Male, Kaplan Meier method, Intention to Treat Analysi, remdesivir, Lopinavir/*therapeutic use, Hydroxychloroquine -- therapeutic use, middle aged, COVID-19 -- mortality, Hospital Mortality, Antiviral Agents/administration & dosage/adverse effects/*therapeutic use, comparative study, beta1a interferon, 0303 health sciences, Alanine, Respiration, adult, clinical trial, Sciences bio-médicales et agricoles, Intention to Treat Analysis, 3. Good health, [SDV] Life Sciences [q-bio], aged, name=Covid19, health care quality, priority journal, drug withdrawal, Artificial, Drug Therapy, Combination, alanine, hospitalization, Human, Interferon beta-1a/*therapeutic use, intention to treat analysis, World Health Organization, Antiviral Agents, Article, 03 medical and health sciences, Drug Therapy, death, Humans, human, treatment failure, Aged, treatment duration, extracorporeal oxygenation, Length of Stay, major clinical study, mortality, Respiration, Artificial, Adenosine Monophosphate/*analogs & derivatives/therapeutic use, multicenter study, Alanine/*analogs & derivatives/therapeutic use, randomized controlled trial, antivirus agent, 0301 basic medicine, Kaplan-Meier Estimate, Lopinavir, Adenosine Monophosphate, COVID-19, Female, Hospitalization, Hydroxychloroquine, Interferon beta-1a, Middle Aged, Treatment Failure, antiviral drugs, Covid-19, Hydroxychloroquine/*therapeutic use, artificial ventilation, General medicine, internal medicine and other clinical medicine, Lopinavir -- therapeutic use, drug therapy, ritonavir, hospital patient, Adenosine Monophosphate -- analogs & derivatives -- therapeutic use, female, Antiviral Agents -- administration & dosage -- adverse effects -- therapeutic use, Combination, Original Article, combination drug therapy, COVID-19/*drug therapy/mortality, hydroxychloroquine, Alanine -- analogs & derivatives -- therapeutic use, drug repositioning, drug clearance, adenosine phosphate, coronavirus disease 2019, length of stay, male, controlled study, hospital mortality, Antiviral Agent, Interferon beta-1a -- therapeutic use, COVID-19 Drug Treatment, lopinavir

Popis súboru: application/pdf; 1 full-text file(s): application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33264556
https://hdl.handle.net/20.500.12530/59115
http://hdl.handle.net/11368/2992403
https://www.nejm.org/doi/10.1056/NEJMoa2023184
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727327/
https://hdl.handle.net/2078.1/269080
http://hdl.handle.net/10138/335523
https://hdl.handle.net/1983/98635126-3b2a-4ee8-8bcd-ed25e5fe26e1
https://research-information.bris.ac.uk/ws/files/259551629/Full_text_PDF_Final_Published_Version_.pdf
https://boris.unibe.ch/149965/
https://hdl.handle.net/11368/2992403
https://doi.org/10.1056/NEJMoa2023184
https://www.nejm.org/doi/10.1056/NEJMoa2023184
https://hdl.handle.net/20.500.12866/9103
https://doi.org/10.1056/NEJMoa2023184
https://hdl.handle.net/2318/1785588
https://doi.org/10.1056/NEJMoa2023184

Safety and Efficacy of Cangrelor in Acute Stroke Treated with Mechanical Thrombectomy: Endovascular Treatment of Ischemic Stroke Registry and Meta-analysis

Autori: Marnat, G. Finistis, S. Delvoye, F. a ďalší

Prispievatelia: Marnat, G. Finistis, S. Delvoye, F. a ďalší

Zdroj: American Journal of Neuroradiology. 43:410-415

Predmety: Radiology, Nuclear Medicine and Imaging, Arterial Occlusive Diseases, Sciences de la santé humaine, Adenosine Monophosphate/analogs & derivatives, Brain Ischemia, Adenosine Monophosphate/therapeutic use, 03 medical and health sciences, 0302 clinical medicine, Neurologie, Ischemic Stroke/therapy, Multicenter Studies as Topic, Humans, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Prospective Studies, Registries, Adenosine Monophosphate/adverse effects, Human health sciences, Retrospective Studies, Cerebral Hemorrhage, Ischemic Stroke, Thrombectomy, Endovascular Procedures, Cerebral Hemorrhage/etiology, Combined Modality Therapy, Adenosine Monophosphate, 3. Good health, Stroke, Treatment Outcome, Neurology, Stents, Neurology (clinical), cangrelor

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35241418

Hyperimmune immunoglobulin for hospitalised patients with COVID-19 (ITAC): a double-blind, placebo-controlled, phase 3, randomised trial: a double-blind, placebo-controlled, phase 3, randomised trial

Autori: Group, The ITAC Study Polizzotto, Mark N Nordwall, Jacqueline a ďalší

Zdroj: Lancet
The Lancet, vol 399, iss 10324
The ITAC (INSIGHT 013) Study Group 2022, 'Hyperimmune immunoglobulin for hospitalised patients with COVID-19 (ITAC) : a double-blind, placebo-controlled, phase 3, randomised trial', The Lancet, vol. 399, no. 10324, pp. 530-540. https://doi.org/10.1016/S0140-6736(22)00101-5

Predmety: Male, 0301 basic medicine, Biomedical and clinical sciences, COVID-19 Vaccines, Internationality, Clinical Sciences, Clinical Trials and Supportive Activities, Inpatients/statistics & numerical data, Medical and Health Sciences, Antiviral Agents, Adenosine Monophosphate/analogs & derivatives, Antibodies, Vaccine Related, ITAC (INSIGHT 013) Study Group, 03 medical and health sciences, Double-Blind Method, Clinical Research, General & Internal Medicine, Humans, Lung, Neutralizing, Hospitalization/statistics & numerical data, Antiviral Agents/therapeutic use, Vaccines, Inpatients, Alanine, Biomedical and Clinical Sciences, Prevention, Evaluation of treatments and therapeutic interventions, Health sciences, COVID-19, Inactivated, Alanine/analogs & derivatives, Articles, Middle Aged, 16. Peace & justice, Antibodies, Neutralizing, Adenosine Monophosphate, 3. Good health, Hospitalization, Emerging Infectious Diseases, Treatment Outcome, Vaccines, Inactivated, 6.1 Pharmaceuticals, Female, COVID-19/therapy

Popis súboru: application/pdf

Prístupová URL adresa: http://www.thelancet.com/article/S0140673622001015/pdf
https://pubmed.ncbi.nlm.nih.gov/35093205
https://portal.findresearcher.sdu.dk/da/publications/119c94a2-5d0b-41af-8995-81a19b4dd077
https://doi.org/10.1016/S0140-6736(22)00101-5
https://discovery-pp.ucl.ac.uk/id/eprint/10143099/
https://escholarship.org/uc/item/3093f0p5

Is Antiviral Treatment with Remdesivir at the Acute Phase of SARS-CoV-2 Infection Effective for Decreasing the Risk of Long-Lasting Post-COVID Symptoms?

Autori: Fernández-de-Las-Peñas, César Franco-Moreno, Anabel Ruiz-Ruigómez, María a ďalší

Zdroj: Fernández-de-Las-Peñas, C, Franco-Moreno, A, Ruiz-Ruigómez, M, Arrieta-Ortubay, E, Ryan-Murua, P, Lumbreras-Bermejo, C, Del-Valle-Loarte, P, Pellicer-Valero, O J, Giordano, R, Arendt-Nielsen, L, Martín-Garrido, I & Torres-Macho, J 2024, 'Is Antiviral Treatment with Remdesivir at the Acute Phase of SARS-CoV-2 Infection Effective for Decreasing the Risk of Long-Lasting Post-COVID Symptoms?', Viruses, vol. 16, no. 6, 947. https://doi.org/10.3390/v16060947

Predmety: Adenosine Monophosphate/analogs & derivatives, Adult, Aged, Alanine/analogs & derivatives, Antiviral Agents/therapeutic use, COVID-19 Drug Treatment, COVID-19/complications, Case-Control Studies, Female, Humans, Male, Middle Aged, Post-Acute COVID-19 Syndrome, SARS-CoV-2/drug effects, remdesivir, antiviral, post-COVID-19, long-COVID

Popis súboru: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/38932239; info:eu-repo/semantics/altIdentifier/pissn/1999-4915

Dostupnosť: https://vbn.aau.dk/da/publications/14e09642-5263-4059-81a7-2c82516eb526
https://doi.org/10.3390/v16060947
https://vbn.aau.dk/ws/files/720335051/viruses-16-00947.pdf
https://www.scopus.com/pages/publications/85197147414

Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial

Autori: Vincent C Marconi Athimalaipet V Ramanan Stephanie de Bono a ďalší

Zdroj: Lancet Respir Med

Predmety: Adult, Asia, COVID-19, Baricitinib, Antiviral Agents, Adenosine Monophosphate/analogs & derivatives, Dexamethasone, Azetidines/therapeutic use, 03 medical and health sciences, Pyrazoles/therapeutic use, 0302 clinical medicine, Double-Blind Method, Adrenal Cortex Hormones, Purines/therapeutic use, Humans, Sulfonamides, Alanine, SARS-CoV-2, Alanine/analogs & derivatives, Articles, Sulfonamides/therapeutic use, South America, 16. Peace & justice, Adenosine Monophosphate, COVID-19 Drug Treatment, 3. Good health, Europe, Treatment Outcome, Purines, North America, Azetidines, Pyrazoles

Popis súboru: application/pdf

Prístupová URL adresa: http://www.thelancet.com/article/S2213260021003313/pdf
https://pubmed.ncbi.nlm.nih.gov/34480861
https://pubmed.ncbi.nlm.nih.gov/34480861/
https://digitalcommons.psjhealth.org/publications/5324/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409066/
https://www.sciencedirect.com/science/article/pii/S2213260021003313
http://europepmc.org/article/MED/34480861
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00331-3/fulltext
https://hdl.handle.net/10281/352601
https://doi.org/10.1016/S2213-2600(21)00331-3

Remdesivir triphosphate blocks DNA synthesis and increases exonucleolysis by the replicative mitochondrial DNA polymerase, Pol γ

Autori: Elena J. Ciesielska Shalom Kim Hyacintha-ghislaine M. Bisimwa a ďalší

Prispievatelia: Elena J. Ciesielska Shalom Kim Hyacintha-ghislaine M. Bisimwa a ďalší

Zdroj: Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Predmety: DNA Replication, 0301 basic medicine, Antiviral nucleoside analogues, pharmacology), Cells, Remdesivir, DNA, Mitochondrial, Fibroblasts (metabolism), 03 medical and health sciences, DNA polymerase gamma, Humans, Cells, Cultured, Alanine (analogs & derivatives, 0303 health sciences, Cultured, Alanine, SARS-CoV-2, COVID-19 (metabolism), Adenosine Monophosphate (analogs & derivatives, DNA Replication (drug effects), COVID-19, DNA, Fibroblasts, Mitochondrial DNA, Adenosine Monophosphate, DNA Polymerase gamma, COVID-19 Drug Treatment, 3. Good health, DNA Polymerase gamma (metabolism), Mitochondrial (biosynthesis)

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/34619353
https://www.sciencedirect.com/science/article/pii/S1567724921001367
https://pubmed.ncbi.nlm.nih.gov/34619353/
https://search.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/en/covidwho-1454362

Cardiovascular events and safety outcomes associated with remdesivir using a World Health Organization international pharmacovigilance database

Autori: Nam Kyun Kim Marco Solmi Salvatore Terrazzino a ďalší

Prispievatelia: Nam Kyun Kim Marco Solmi Salvatore Terrazzino a ďalší

Zdroj: Clin Transl Sci
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Clinical and Translational Science, Vol 15, Iss 2, Pp 501-513 (2022)

Predmety: Alanine / adverse effects, Adenosine Monophosphate / adverse effects, Adenosine Monophosphate / analogs & derivatives, Antiviral Agents / adverse effects, Databases, Factual, [SDV]Life Sciences [q-bio], RM1-950, World Health Organization, Antiviral Agents, Databases, Pharmacovigilance, 03 medical and health sciences, 0302 clinical medicine, Annan medicinsk grundvetenskap, Humans, Myocytes, Cardiac, Other Basic Medicine, Factual, Retrospective Studies, Myocytes, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Alanine, SARS-CoV-2, Research, VIGIBASE, COVID-19, 16. Peace & justice, Adenosine Monophosphate, COVID-19 Drug Treatment, 3. Good health, [SDV] Life Sciences [q-bio], Alanine / analogs & derivatives, COVID-19 / drug therapy, Cardiovascular Diseases / chemically induced, Cardiovascular Diseases, Cardiac / drug effects, Therapeutics. Pharmacology, Public aspects of medicine, RA1-1270, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

Popis súboru: application/pdf; STAMPA

Prístupová URL adresa: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cts.13168
https://pubmed.ncbi.nlm.nih.gov/34719115
https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=20245
https://ascpt.onlinelibrary.wiley.com/doi/10.1111/cts.13168
https://arro.anglia.ac.uk/id/eprint/707069/11/Jung_et_al_2021.pdf
https://doaj.org/article/193ae135de354dc99bb9951ef20e5f30
https://hal.uvsq.fr/hal-03416916v1
https://pubmed.ncbi.nlm.nih.gov/34719115/
https://www.ncbi.nlm.nih.gov/pubmed/34719115
https://search.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/zh/covidwho-1494654
https://ascpt.onlinelibrary.wiley.com/doi/10.1111/cts.13168
https://arro.anglia.ac.uk/id/eprint/707069/
https://hal.sorbonne-universite.fr/hal-03416916v1
https://hal.sorbonne-universite.fr/hal-03416916v1/document
https://doi.org/10.1111/cts.13168
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-181065

A Multicenter Preliminary Study of Cangrelor following Thrombectomy Failure for Refractory Proximal Intracranial Occlusions

Autori: Marnat, Gaultier Delvoye, François Finitsis, S a ďalší

Prispievatelia: Marnat, Gaultier Delvoye, François Finitsis, S a ďalší

Zdroj: American Journal of Neuroradiology. 42:1452-1457

Predmety: Radiology, Nuclear Medicine and Imaging, Sciences de la santé humaine, Adenosine Monophosphate/analogs & derivatives, Adenosine Monophosphate, 3. Good health, Stroke, 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, Neurology, Stroke/surgery, Neurologie, Humans, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Neurology (clinical), Prospective Studies, Human health sciences, Stroke/drug therapy, cangrelor, Retrospective Studies, Thrombectomy

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/34117019
http://www.ajnr.org/content/42/8/1452
https://europepmc.org/article/MED/34117019
https://www.ncbi.nlm.nih.gov/pubmed/34117019
https://hdl.handle.net/2268/324565
https://doi.org/10.3174/ajnr.A7180
https://hal.science/hal-03401850v1
https://doi.org/10.3174/ajnr.a7180

Improved Survival Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Treated With Remdesivir and Dexamethasone. A Nationwide Population-Based Cohort Study

Autori: Marie Helleberg Christian N Meyer Claire Præst Holm a ďalší

Zdroj: Benfield, T, Bodilsen, J, Brieghel, C, Harboe, Z B, Helleberg, M, Holm, C, Israelsen, S B, Jensen, J, Jensen, T Ø, Johansen, I S, Johnsen, S, Madsen, B L, Lundgren, J, Meyer, C N, Mohey, R, Pedersen, L M, Nielsen, H, Nielsen, S L, Obel, N, Omland, L H, Podlekareva, D, Poulsen, B K, Ravn, P, Sandholdt, H, Starling, J, Storgaard, M, Søborg, C, Søgaard, O S, Tranborg, T, Wiese, L & Christensen, H R 2021, 'Improved Survival Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Treated With Remdesivir and Dexamethasone. A Nationwide Population-Based Cohort Study', Clinical Infectious Diseases, vol. 73, no. 11, ciab536, pp. 2031-2036. https://doi.org/10.1093/cid/ciab536
Benfield, T, Bodilsen, J, Brieghel, C, Harboe, Z B, Helleberg, M, Holm, C, Israelsen, S B, Jensen, J, Jensen, T Ø, Johansen, I S, Johnsen, S, Madsen, B L, Lundgren, J, Meyer, C N, Mohey, R, Pedersen, L M, Nielsen, H, Nielsen, S L, Obel, N, Omland, L H, Podlekareva, D, Poulsen, B K, Ravn, P, Sandholdt, H, Starling, J, Storgaard, M, Søborg, C, Søgaard, O S, Tranborg, T, Wiese, L & Christensen, H R 2021, ' Improved Survival Among Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Treated With Remdesivir and Dexamethasone. A Nationwide Population-Based Cohort Study ', Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 73, no. 11, pp. 2031-2036 . https://doi.org/10.1093/cid/ciab536

Predmety: Antiviral Agents/therapeutic use, 0301 basic medicine, Alanine, SARS-CoV-2, COVID-19, dexamethasone, remdesivir, Alanine/analogs & derivatives, COVID-19/drug therapy, survival, Antiviral Agents, Adenosine Monophosphate/analogs & derivatives, Dexamethasone/therapeutic use, Adenosine Monophosphate, Dexamethasone, COVID-19 Drug Treatment, 3. Good health, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, pneumonia, Humans, Retrospective Studies

Prístupová URL adresa: https://academic.oup.com/cid/article-pdf/73/11/2031/41608413/ciab536.pdf
https://pubmed.ncbi.nlm.nih.gov/34111274
https://europepmc.org/article/MED/34111274
https://vbn.aau.dk/en/publications/improved-survival-among-hospitalized-patients-with-covid-19-treat
https://pure-portal.regsj.dk/da/publications/improved-survival-among-hospitalized-patients-with-coronavirus-di
https://portal.findresearcher.sdu.dk/en/publications/improved-survival-among-hospitalized-patients-with-covid-19-treat
https://www.ncbi.nlm.nih.gov/pubmed/34111274
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344480
https://portal.findresearcher.sdu.dk/da/publications/602f10fd-a7bb-4879-ae11-16f97bdb9a37

A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19

Autori: Estelle S. Harris Jason V. Baker B. Taylor Thompson a ďalší

Zdroj: N Engl J Med
Lundgren, J D, Grund, B, Barkauskas, C E, Holland, T L, Gottlieb, R L, Sandkovsky, U, Brown, S M, Knowlton, K U, Self, W H, Files, D C, Jain, M K, Benfield, T, Bowdish, M E, Leshnower, B G, Baker, J V, Jensen, J-U, Gardner, E M, Ginde, A A, Harris, E S, Johansen, I S, Markowitz, N, Matthay, M A, Østergaard, L, Chang, C C, Davey, V J, Goodman, A, Higgs, E S, Murray, D D, Murray, T A, Paredes, R, Parmar, M K B, Phillips, A N, Reilly, C, Sharma, S, Dewar, R L, Teitelbaum, M, Wentworth, D, Cao, H, Klekotka, P, Babiker, A G, Gelijns, A C, Kan, V L, Polizzotto, M N, Thompson, B T, Lane, H C, Neaton, J D, TICO Study Group, Nielsen, H, ACTIV-3/TICO LY-CoV555 Study Group & Writing Commitee 2021, 'A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19', The New England Journal of Medicine, vol. 384, no. 10, pp. 905-914. https://doi.org/10.1056/NEJMoa2033130
ACTIV-3/TICO LY-CoV555 Study Group 2021, 'A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19', The New England Journal of Medicine, vol. 384, no. 10, pp. 905-914. https://doi.org/10.1056/NEJMoa2033130
ACTIV-3/TICO LY-CoV555 Study Group 2021, ' A neutralizing monoclonal antibody for hospitalized patients with Covid-19 ', New England Journal of Medicine, vol. 384, no. 10, pp. 905-914 . https://doi.org/10.1056/NEJMoa2033130
Lundgren, J D, Grund, B, Barkauskas, C E, Holland, T L, Gottlieb, R L, Sandkovsky, U, Brown, S M, Knowlton, K U, Self, W H, Files, D C, Jain, M K, Benfield, T, Bowdish, M E, Leshnower, B G, Baker, J V, Jensen, J U, Gardner, E M, Ginde, A A, Harris, E S, Johansen, I S, Markowitz, N, Matthay, M A, Østergaard, L, Chang, C C, Davey, V J, Goodman, A, Higgs, E S, Murray, D D, Murray, T A, Paredes, R, Parmar, M K B, Phillips, A N, Reilly, C, Sharma, S, Dewar, R L, Teitelbaum, M, Wentworth, D, Cao, H, Klekotka, P, Babiker, A G, Gelijns, A C, Kan, V L, Polizzotto, M N, Thompson, B T, Lane, H C, Neaton, J D & ACTIV-3/TICO LY-CoV555 Study Group 2021, ' A neutralizing monoclonal antibody for hospitalized patients with Covid-19 ', New England Journal of Medicine, vol. 384, no. 10, pp. 905-914 . https://doi.org/10.1056/NEJMoa2033130

Predmety: Glucocorticoids/therapeutic use, Adult, Male, 0301 basic medicine, Antibodies, Monoclonal, Humanized, COVID-19/drug therapy, Antiviral Agents, Antibodies, Adenosine Monophosphate/analogs & derivatives, 03 medical and health sciences, Drug Therapy, Double-Blind Method, Monoclonal, Humans, Treatment Failure, Glucocorticoids, Aged, Alanine, COVID-19, Neutralizing/adverse effects, Alanine/analogs & derivatives, Middle Aged, Antiviral Agents/adverse effects, Antibodies, Neutralizing, Antibodies, Neutralizing/adverse effects, Adenosine Monophosphate, Intention to Treat Analysis, COVID-19 Drug Treatment, 3. Good health, Hospitalization, Antibodies, Monoclonal, Humanized/adverse effects, Combination, Original Article, Drug Therapy, Combination, Female, Humanized/adverse effects

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/33356051
https://vbn.aau.dk/da/publications/b270161e-4ef1-4a73-a42b-7e358e9ee9c3
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781100/pdf/NEJMoa2033130.pdf
https://doi.org/10.1056/NEJMoa2033130
http://www.scopus.com/inward/record.url?scp=85099949020&partnerID=8YFLogxK
https://pure.au.dk/portal/en/publications/f31200af-4c9e-4290-9824-4f4f1fc165d1
https://curis.ku.dk/ws/files/290115626/A_Neutralizing_Monoclonal_Antibod.pdf
https://portal.findresearcher.sdu.dk/da/publications/cd272378-cae6-4d23-bc95-bf5a750d6684
https://doi.org/10.1056/NEJMoa2033130
https://findresearcher.sdu.dk:8443/ws/files/180856467/nejmoa2033130.pdf
https://pure.au.dk/portal/en/publications/f31200af-4c9e-4290-9824-4f4f1fc165d1
https://pure.au.dk/ws/files/275347137/A_Neutralizing_Monoclonal_Antibody_for_Hospitalized_Patients_with_Covid_19.pdf
https://doi.org/10.1056/NEJMoa2033130
http://www.scopus.com/inward/record.url?scp=85099949020&partnerID=8YFLogxK

Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update

Autori: Yaseen M. Arabi Greg S. Martin Craig M. Coopersmith a ďalší

Prispievatelia: Yaseen M. Arabi Greg S. Martin Craig M. Coopersmith a ďalší

Zdroj: Alhazzani, W, Evans, L, Alshamsi, F, Møller, M H, Ostermann, M, Prescott, H C, Arabi, Y M, Loeb, M, Ng Gong, M, Fan, E, Oczkowski, S, Levy, M M, Derde, L, Dzierba, A, Du, B, MacHado, F, Wunsch, H, Crowther, M, Cecconi, M, Koh, Y, Burry, L, Chertow, D S, Szczeklik, W, Belley-Cote, E, Greco, M, Bala, M, Zarychanski, R, Kesecioglu, J, McGeer, A, Mermel, L, Mammen, M J, Nainan Myatra, S, Arrington, A, Kleinpell, R, Citerio, G, Lewis, K, Bridges, E, Memish, Z A, Hammond, N, Hayden, F G, Alshahrani, M, Al Duhailib, Z, Martin, G S, Kaplan, L J, Coopersmith, C M, Antonelli, M & Rhodes, A 2021, ' Surviving Sepsis Campaign Guidelines on the Management of Adults with Coronavirus Disease 2019 (COVID-19) in the ICU : First Update ', Critical Care Medicine, vol. 49, no. 3, pp. E219-E234 . https://doi.org/10.1097/CCM.0000000000004899
Critical Care Medicine

Predmety: Critical Care, Adrenal Cortex Hormones/therapeutic use, Critical Care and Intensive Care Medicine, Adenosine Monophosphate/analogs & derivatives, Dexamethasone, Patient Positioning, 03 medical and health sciences, 0302 clinical medicine, Surviving Sepsis Campaign, Guidelines, Adults, Coronavirus Disease 2019 (COVID-19), ICU, Adrenal Cortex Hormones, Journal Article, Humans, COVID-19 Serotherapy, Alanine, Evidence-Based Medicine, Hemodynamics, Immunization, Passive, Anticoagulants, COVID-19, Disease Management, Alanine/analogs & derivatives, Dexamethasone/therapeutic use, Adenosine Monophosphate, Ventilation, 3. Good health, Intensive Care Units, Practice Guidelines as Topic, Research Support, U.S. Gov't, Non-P.H.S, COVID-19/therapy, Hydroxychloroquine

Popis súboru: application/pdf

Prístupová URL adresa: https://journals.lww.com/ccmjournal/Fulltext/2021/03000/Surviving_Sepsis_Campaign_Guidelines_on_the.21.aspx
https://pubmed.ncbi.nlm.nih.gov/33555780
https://journals.lww.com/ccmjournal/Fulltext/2021/03000/Surviving_Sepsis_Campaign_Guidelines_on_the.21.aspx
https://doi.org/10.1097/CCM.0000000000004899
https://dspace.library.uu.nl/handle/1874/442507
https://curis.ku.dk/ws/files/331774901/Surviving_Sepsis_Campaign_Guidelines_on_the.21.pdf
https://ruj.uj.edu.pl/xmlui/handle/item/270369

Treatment of severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and coronavirus disease 2019 (COVID-19): a systematic review of in vitro, in vivo, and clinical trials

Autori: Han, Youngjoo Lee, Keum-Hwa Yoon, Sojung a ďalší

Prispievatelia: Han, Youngjoo Lee, Keum-Hwa Yoon, Sojung a ďalší

Zdroj: Theranostics
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname

Predmety: 0301 basic medicine, Pyrrolidines, Adenosine Monophosphate / therapeutic use, coronavirus, Drug Evaluation, Preclinical, Review, Severe Acute Respiratory Syndrome, mortality, Valine / therapeutic use, Antiviral Agents / therapeutic use, Randomized Controlled Trials as Topic, Valine / analogs & derivatives, 0303 health sciences, Alanine, Imidazoles, Sofosbuvir / therapeutic use, Valine, Preclinical, 3. Good health, Pyrrolidines / therapeutic use, Drug Combinations, COVID-19 / mortality, Treatment Outcome, SARS, Drug Therapy, Combination, therapeutic agent, Alanine / therapeutic use, Combination / methods, COVID-19, Coronavirus Infections, MERS, [SDV.CAN]Life Sciences [q-bio]/Cancer, Adenosine Monophosphate / analogs & derivatives, Carbamates / therapeutic use, Antiviral Agents, Severe Acute Respiratory Syndrome / therapy, Passive / methods, 03 medical and health sciences, Alanine / analogs & derivatives, Coronavirus Infections / therapy, Drug Therapy, Severe Acute Respiratory Syndrome / mortality, Animals, Humans, Mortality, Therapeutic agent, Cancer och onkologi, Animal, Immunization, Passive, Adenosine Monophosphate, Coronavirus, COVID-19 / therapy, Imidazoles / therapeutic use, Disease Models, Animal, Coronavirus Infections / mortality, Cancer and Oncology, Disease Models, Drug Evaluation, Immunization, Carbamates, Sofosbuvir

Popis súboru: application/pdf

Prístupová URL adresa: https://europepmc.org/articles/pmc7738873?pdf=render
https://pubmed.ncbi.nlm.nih.gov/33391531
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18601
https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=18601
https://arro.anglia.ac.uk/id/eprint/706008/5/Han_et_al_2020.pdf
https://yonsei.pure.elsevier.com/en/publications/treatment-of-severe-acute-respiratory-syndrome-sars-middle-east-r
https://www.ncbi.nlm.nih.gov/pubmed/33391531
https://www.thno.org/v11p1207.htm
https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/181969/1/T202100076.pdf
https://ir.ymlib.yonsei.ac.kr/handle/22282913/181969
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-171952

Psychiatric Disorders and Hydroxychloroquine for Coronavirus Disease 2019 (COVID-19): A VigiBase Study

Autori: Yannick Degboé François Montastruc Alexis Revet a ďalší

Prispievatelia: Yannick Degboé François Montastruc Alexis Revet a ďalší

Zdroj: Drug Saf
Drug Safety

Predmety: Male, Hallucinations, Databases, Pharmaceutical, Toxicology, Lopinavir, MESH: Adenosine Monophosphate / analogs & derivatives, 0302 clinical medicine, Monoclonal, 80 and over, Pharmacology (medical), Original Research Article, MESH: Lopinavir / adverse effects, MESH: Aged, Aged, 80 and over, Alanine, Mental Disorders, MESH: Hallucinations / chemically induced, Middle Aged, 3. Good health, Drug Combinations, MESH: Hydroxychloroquine / adverse effects, MESH: COVID-19 Drug Treatment, Female, Hydroxychloroquine, Adult, Humanized / adverse effects, Antibodies, Monoclonal, Humanized, Antiviral Agents, MESH: Databases, MESH: Antiviral Agents / adverse effects, Psychoses, Substance-Induced, 03 medical and health sciences, Humans, MESH: Hallucinations / epidemiology, Aged, MESH: Drug Combinations, Pharmacology, MESH: Adenosine Monophosphate / adverse effects, MESH: Humans, Ritonavir, MESH: Antibodies, MESH: Adult, MESH: Alanine / analogs & derivatives, MESH: Male, Adenosine Monophosphate, Pharmaceutical, MESH: Alanine / adverse effects, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, MESH: Female, Self-Injurious Behavior

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s40264-020-01013-3.pdf
https://pubmed.ncbi.nlm.nih.gov/33078372

Compassionate Use of Remdesivir in Pregnant Women With Severe Coronavirus Disease 2019

Autori: William R. Short Ilona T. Goldfarb Anu Osinusi a ďalší

Zdroj: Clin Infect Dis
Clinical infectious diseases, vol. 73, no. 11, pp. e3996-e4004
Clinical Infectious Diseases

Predmety: Microbiology (medical), Adult, Compassionate Use Trials, Alanine, SARS-CoV-2, Infant, Adenosine Monophosphate, Pregnant People, COVID-19 Drug Treatment, 3. Good health, 03 medical and health sciences, Infectious Diseases, 0302 clinical medicine, Oxygen Saturation, Pregnancy, Humans, Female, Pregnancy Complications, Infectious, Online Only Articles, Adenosine Monophosphate/analogs & derivatives, Alanine/analogs & derivatives, COVID-19/drug therapy, Pregnancy Complications, Infectious/drug therapy, Pregnant Women, COVID-19, pregnant, recovery, remdesivir, ventilation

Popis súboru: application/pdf

Prístupová URL adresa: https://academic.oup.com/cid/article-pdf/73/11/e3996/41608183/ciaa1466.pdf
https://pubmed.ncbi.nlm.nih.gov/33031500
https://serval.unil.ch/resource/serval:BIB_90F193837F76.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_90F193837F765
https://serval.unil.ch/notice/serval:BIB_90F193837F76

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Autori: Ko Yung Sit Ren Sun Raveen Rathnasinghe a ďalší

Zdroj: Nature, vol 586, iss 7827
Nature

Predmety: 0301 basic medicine, Coronaviruses, 302091 Immuntherapie, Drug Evaluation, Preclinical, Gene Expression Regulation/drug effects, Alveolar Epithelial Cells/cytology, Virus Replication, POSTMENOPAUSAL OSTEOPOROSIS, Morpholines/analysis, ONO-5334, Coronaviruses Therapeutics and Interventions, Induced Pluripotent Stem Cells/cytology, PIKFYVE, Models, 302091 Immunotherapy, Viral, 106052 Cell biology, Lung, 106022 Mikrobiologie, 0303 health sciences, Multidisciplinary, Betacoronavirus/drug effects, Alanine, Triazines, APILIMOD, Drug Synergism, Alanine/analogs & derivatives, Preclinical, Triazines/analysis, 3. Good health, EBOLA-VIRUS, Infectious Diseases, Medical Microbiology, 5.1 Pharmaceuticals, SDG 3 – Gesundheit und Wohlergehen, Pneumonia & Influenza, 106022 Microbiology, 106052 Zellbiologie, Drug, Infection, Coronavirus Infections, General Science & Technology, Morpholines, Induced Pluripotent Stem Cells, Cysteine Proteinase Inhibitors, Antiviral Agents, Models, Biological, Adenosine Monophosphate/analogs & derivatives, Cell Line, Small Molecule Libraries, Dose-Response Relationship, Betacoronavirus, 03 medical and health sciences, Rare Diseases, SDG 3 - Good Health and Well-being, Antiviral Agents/analysis, Small Molecule Libraries/analysis, KINASE, Humans, Viral/drug therapy, Pandemics, Virus Replication/drug effects, Biomedical and Clinical Sciences, Dose-Response Relationship, Drug, SARS-CoV-2, Drug Repositioning, Hydrazones, Reproducibility of Results, COVID-19, Coronavirus Infections/drug therapy, Pneumonia, Virus Internalization, Stem Cell Research, Biological, EFFICACY, Adenosine Monophosphate, COVID-19 Drug Treatment, Virus Internalization/drug effects, Good Health and Well Being, Orphan Drug, Emerging Infectious Diseases, Pyrimidines, IL-12/IL-23 INHIBITOR, Gene Expression Regulation, CATHEPSIN-L, Alveolar Epithelial Cells, REPLICATION, Drug Evaluation, Cysteine Proteinase Inhibitors/analysis

Popis súboru: application/pdf

Prístupová URL adresa: https://www.nature.com/articles/s41586-020-2577-1.pdf
https://pubmed.ncbi.nlm.nih.gov/32707573
https://ucrisportal.univie.ac.at/de/publications/5e0e71b3-7b21-41ba-a0f2-eddf86ce60e7
https://doi.org/10.1038/s41586-020-2577-1
http://vlib.kmu.ac.ir/kmu/handle/kmu/891293
http://vlib.kmu.ac.ir/kmu/handle/kmu/912560
https://escholarship.org/content/qt6p88f41f/qt6p88f41f.pdf
https://escholarship.org/uc/item/6p88f41f

Utilization of COVID-19 Treatments and Clinical Outcomes among Patients with Cancer: A COVID-19 and Cancer Consortium (CCC19) Cohort Study.

Autori: Rivera, D.R. Peters, S. Panagiotou, O.A. a ďalší

Prispievatelia: Rivera, D.R. Peters, S. Panagiotou, O.A. a ďalší

Predmety: Adenosine Monophosphate/analogs & derivatives, Adenosine Monophosphate/therapeutic use, Age Factors, Aged, Alanine/analogs & derivatives, Alanine/therapeutic use, Betacoronavirus/pathogenicity, Clinical Decision-Making, Coronavirus Infections/complications, Coronavirus Infections/diagnosis, Coronavirus Infections/drug therapy, Coronavirus Infections/mortality, Drug Therapy, Combination/methods, Combination/statistics & numerical data, Drug Utilization/statistics & numerical data, Follow-Up Studies, Glucocorticoids/therapeutic use, Healthcare Disparities/statistics & numerical data, Hospital Mortality, Humans, Hydroxychloroquine/therapeutic use, Male, Middle Aged, Neoplasms/complications, Neoplasms/mortality, Pandemics, Pneumonia, Viral/complications, Viral/diagnosis

Popis súboru: application/pdf

Relation: Cancer Discovery; https://iris.unil.ch/handle/iris/97141; serval:BIB_2286AC0B4000; 000576792800026

Dostupnosť: https://iris.unil.ch/handle/iris/97141
https://doi.org/10.1158/2159-8290.CD-20-0941

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses.

Autori: Pan, H. WHO Solidarity Trial Consortium Peto, R. a ďalší

Prispievatelia: Pan, H. WHO Solidarity Trial Consortium Peto, R. a ďalší

Predmety: Adenosine Monophosphate/analogs & derivatives, Adenosine Monophosphate/therapeutic use, Adult, Alanine/analogs & derivatives, Alanine/therapeutic use, Antiviral Agents/therapeutic use, Humans, Hydroxychloroquine/therapeutic use, Interferon beta-1a/therapeutic use, Lopinavir/therapeutic use, Oxygen/administration & dosage, Randomized Controlled Trials as Topic, Treatment Outcome, World Health Organization, COVID-19 Drug Treatment

Popis súboru: application/pdf

Relation: The Lancet; https://iris.unil.ch/handle/iris/259427; serval:BIB_E7449A3BEA46; 000804936100017

Dostupnosť: https://iris.unil.ch/handle/iris/259427
https://doi.org/10.1016/S0140-6736(22)00519-0

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

Autori: Pan, H. WHO Solidarity Trial Consortium Peto, R. a ďalší

Prispievatelia: Pan, H. WHO Solidarity Trial Consortium Peto, R. a ďalší

Zdroj: Lancet, vol. 399, no. 10339, pp. 1941-1953

Predmety: Adenosine Monophosphate/analogs & derivatives, Adenosine Monophosphate/therapeutic use, Adult, Alanine/analogs & derivatives, Alanine/therapeutic use, Antiviral Agents/therapeutic use, Humans, Hydroxychloroquine/therapeutic use, Interferon beta-1a/therapeutic use, Lopinavir/therapeutic use, Oxygen/administration & dosage, Randomized Controlled Trials as Topic, Treatment Outcome, World Health Organization, COVID-19 Drug Treatment

Popis súboru: application/pdf

Prístupová URL adresa: http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E7449A3BEA461
https://serval.unil.ch/resource/serval:BIB_E7449A3BEA46.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_E7449A3BEA46
https://europepmc.org/articles/PMC9060606