Výsledky vyhľadávania - "Activin Receptors, Type II"

Efficacy and safety of luspatercept in non-transfusion-dependent β-thalassemia: long-term results from the BEYOND study.

Autori: Taher AT Viprakasit V Kattamis A a ďalší

Zdroj: Blood advances [Blood Adv] 2025 Dec 09; Vol. 9 (23), pp. 6108-6119.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study

Informácie o časopise: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

Výrazy zo slovníka MeSH: beta-Thalassemia*/drug therapy , beta-Thalassemia*/blood , Immunoglobulin Fc Fragments*/therapeutic use , Immunoglobulin Fc Fragments*/adverse effects , Immunoglobulin Fc Fragments*/administration & dosage , Recombinant Fusion Proteins*/therapeutic use , Recombinant Fusion Proteins*/adverse effects , Recombinant Fusion Proteins*/administration & dosage , Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage, Humans ; Male ; Female ; Adult ; Treatment Outcome ; Adolescent ; Young Adult ; Middle Aged ; Double-Blind Method ; Child

Luspatercept for the treatment of lower-risk myelodysplastic syndrome with SF3B1 mutation: a real-world single-center research in China.

Autori: Liang W Kang R Zhao Y a ďalší

Zdroj: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2506858. Date of Electronic Publication: 2025 Jun 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/genetics , RNA Splicing Factors*/genetics , Immunoglobulin Fc Fragments*/therapeutic use , Immunoglobulin Fc Fragments*/administration & dosage , Immunoglobulin Fc Fragments*/adverse effects , Recombinant Fusion Proteins*/therapeutic use , Recombinant Fusion Proteins*/adverse effects , Recombinant Fusion Proteins*/administration & dosage , Mutation* , Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage, Humans ; Male ; Female ; Middle Aged ; Aged ; China ; Retrospective Studies ; Treatment Outcome ; Phosphoproteins

Activin receptor type IIA/IIB blockade increases muscle mass and strength, but compromises glycemic control in mice.

Autori: Carlsson M Frank E Màrmol JM a ďalší

Zdroj: Molecular metabolism [Mol Metab] 2025 Dec; Vol. 102, pp. 102261. Date of Electronic Publication: 2025 Sep 27.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycemic Control* , Activin Receptors, Type II*/antagonists & inhibitors , Muscle, Skeletal*/anatomy & histology , Muscle, Skeletal*/drug effects , Muscle, Skeletal*/physiology , Muscle Strength*/drug effects, Animals ; Mice ; Blood Glucose/drug effects ; Blood Glucose/metabolism ; Mice, Obese ; Glucose Intolerance ; Humans ; Insulin Resistance ; Adipose Tissue/drug effects ; Adipose Tissue/metabolism ; Running ; Male ; Mice, Inbred C57BL

Gel Electrophoretic Detection of Black Market ACE-031.

Autori: Reichel C Filip T Gmeiner G a ďalší

Zdroj: Drug testing and analysis [Drug Test Anal] 2025 Oct; Vol. 17 (10), pp. 1934-1946. Date of Electronic Publication: 2025 May 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 101483449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-7611 (Electronic) Linking ISSN: 19427603 NLM ISO Abbreviation: Drug Test Anal Subsets: MEDLINE

Výrazy zo slovníka MeSH: Electrophoresis, Polyacrylamide Gel*/methods , Activin Receptors, Type II*/analysis , Recombinant Fusion Proteins*/analysis , Performance-Enhancing Substances*/analysis, Humans ; Animals ; Rats ; Blotting, Western/methods ; Immunoglobulin Fc Fragments/analysis

SMAD5 phosphorylation by ALK1 is modulated by the interaction of the spike protein of SARS-CoV-2 and angiotensin-converting enzyme 2.

Autori: Teratake Y Okamura T Ishizaka Y

Zdroj: Antiviral research [Antiviral Res] 2025 Oct; Vol. 242, pp. 106261. Date of Electronic Publication: 2025 Aug 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Angiotensin-Converting Enzyme 2*/metabolism , Spike Glycoprotein, Coronavirus*/metabolism , SARS-CoV-2*/metabolism , Smad5 Protein*/metabolism , Activin Receptors, Type II*/metabolism, Humans ; Phosphorylation ; COVID-19/metabolism ; HEK293 Cells ; Protein Binding

Generation of patient-derived and gene-corrected hiPSC lines from Hereditary Hemorrhagic Telangiectasia type 2 patients with ACVRL1 c.1042delG mutation.

Autori: Urdaneta KE van den Hil FE Bouma MJ a ďalší

Zdroj: Stem cell research [Stem Cell Res] 2025 Oct; Vol. 88, pp. 103812. Date of Electronic Publication: 2025 Aug 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101316957 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-7753 (Electronic) Linking ISSN: 18735061 NLM ISO Abbreviation: Stem Cell Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Telangiectasia, Hereditary Hemorrhagic*/genetics , Telangiectasia, Hereditary Hemorrhagic*/pathology , Telangiectasia, Hereditary Hemorrhagic*/metabolism , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/cytology , Activin Receptors, Type II*/genetics , Mutation*, Humans ; Cell Line ; Male ; Female ; Cell Differentiation

Hereditary Hemorrhagic Telangiectasia Prevalence Estimates Calculated From GnomAD Allele Frequencies of Predicted Pathogenic Variants in ENG and ACVRL1 .

Autori: Anzell AR M White C Diergaarde B a ďalší

Zdroj: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2025 Oct; Vol. 18 (5), pp. e005061. Date of Electronic Publication: 2025 Sep 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101714113 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2574-8300 (Electronic) Linking ISSN: 25748300 NLM ISO Abbreviation: Circ Genom Precis Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Telangiectasia, Hereditary Hemorrhagic*/genetics , Telangiectasia, Hereditary Hemorrhagic*/epidemiology , Activin Receptors, Type II*/genetics , Endoglin*/genetics , Gene Frequency*, Humans ; Prevalence

CryoEM structure of ALK2:BMP6 reveals distinct mechanism that allow ALK2 to interact with both BMP and activin ligands.

Autori: Goebel EJ Aykul S Hom WW a ďalší

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Sep 02; Vol. 122 (35), pp. e2502788122. Date of Electronic Publication: 2025 Aug 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy zo slovníka MeSH: Activin Receptors, Type I*/metabolism , Activin Receptors, Type I*/chemistry , Activin Receptors, Type I*/genetics , Activins*/metabolism , Activins*/chemistry , Bone Morphogenetic Protein 6*/metabolism , Bone Morphogenetic Protein 6*/chemistry , Activin Receptors, Type II*/metabolism , Activin Receptors, Type II*/chemistry, Humans ; Cryoelectron Microscopy ; Ligands ; Protein Binding ; Signal Transduction ; Animals

[Luspatercept combined with roxadustat in the treatment of refractory myelodysplastic neoplasms with ring sideroblasts: a prospective, randomized, single-center study].

Autori: Lu XY Zhang ZX Liu ZW a ďalší

Zdroj: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi [Zhonghua Xue Ye Xue Za Zhi] 2025 Jul 14; Vol. 46 (7), pp. 625-630.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; English Abstract

Informácie o časopise: Publisher: Chinese Medical Association Country of Publication: China NLM ID: 8212398 Publication Model: Print Cited Medium: Print ISSN: 0253-2727 (Print) Linking ISSN: 02532727 NLM ISO Abbreviation: Zhonghua Xue Ye Xue Za Zhi Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycine*/analogs & derivatives , Glycine*/therapeutic use , Glycine*/administration & dosage , Isoquinolines*/therapeutic use , Isoquinolines*/administration & dosage , Recombinant Fusion Proteins*/therapeutic use , Recombinant Fusion Proteins*/administration & dosage , Immunoglobulin Fc Fragments*/therapeutic use , Immunoglobulin Fc Fragments*/administration & dosage , Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage , Myelodysplastic Syndromes*/drug therapy, Humans ; Middle Aged ; Male ; Prospective Studies ; Female ; Aged ; Adult ; Treatment Outcome ; Drug Therapy, Combination

Real world efficacy of luspatercept in patients with lower-risk myelodysplastic syndromes/neoplasms (MDS); a single center study in a heavily pretreated cohort.

Autori: Kometas ML Hoff FW Hyak J a ďalší

Zdroj: Leukemia & lymphoma [Leuk Lymphoma] 2025 Jul; Vol. 66 (7), pp. 1245-1253. Date of Electronic Publication: 2025 Mar 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1029-2403 (Electronic) Linking ISSN: 10268022 NLM ISO Abbreviation: Leuk Lymphoma Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myelodysplastic Syndromes*/complications , Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/mortality , Myelodysplastic Syndromes*/diagnosis , Recombinant Fusion Proteins*/therapeutic use , Recombinant Fusion Proteins*/adverse effects , Recombinant Fusion Proteins*/administration & dosage , Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage , Anemia*/etiology , Anemia*/drug therapy , Immunoglobulin Fc Fragments*/therapeutic use , Immunoglobulin Fc Fragments*/adverse effects, Humans ; Male ; Female ; Aged ; Middle Aged ; Retrospective Studies ; Treatment Outcome ; Aged, 80 and over ; Adult ; Blood Transfusion

Molecular mechanism of Activin receptor inhibition by DLK1.

Autori: Antfolk D Ming Q Manturova A a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Jul 01; Vol. 16 (1), pp. 5976. Date of Electronic Publication: 2025 Jul 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Activin Receptors, Type II*/metabolism , Activin Receptors, Type II*/chemistry , Activin Receptors, Type II*/genetics , Activin Receptors, Type II*/antagonists & inhibitors , Calcium-Binding Proteins*/metabolism , Intercellular Signaling Peptides and Proteins*/metabolism , Intercellular Signaling Peptides and Proteins*/chemistry , Intercellular Signaling Peptides and Proteins*/genetics, Humans ; Signal Transduction ; Animals ; Transforming Growth Factor beta/metabolism ; Mice ; Cell Differentiation ; HEK293 Cells ; Receptors, Notch/metabolism ; Myoblasts/metabolism ; Myoblasts/cytology ; Myostatin/metabolism ; Smad2 Protein/metabolism ; Protein Binding ; Smad3 Protein/metabolism ; Crystallography, X-Ray ; Muscle Development ; Membrane Proteins

Long-Term Transfusion Independence with Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent-Naive, Lower-Risk Myelodysplastic Syndromes in the COMMANDS Trial.

Autori: Garcia-Manero G Santini V Zeidan AM a ďalší

Zdroj: Advances in therapy [Adv Ther] 2025 Jul; Vol. 42 (7), pp. 3576-3589. Date of Electronic Publication: 2025 May 16.

Spôsob vydávania: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Comparative Study

Informácie o časopise: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE

Výrazy zo slovníka MeSH: Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage , Anemia*/etiology , Anemia*/drug therapy , Epoetin Alfa*/therapeutic use , Epoetin Alfa*/adverse effects , Epoetin Alfa*/administration & dosage , Erythrocyte Transfusion* , Hematinics*/therapeutic use , Hematinics*/adverse effects , Immunoglobulin Fc Fragments*/therapeutic use , Myelodysplastic Syndromes*/complications , Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/therapy, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Blood Transfusion ; CD47 Antigen/therapeutic use ; Recombinant Fusion Proteins/therapeutic use ; Recombinant Fusion Proteins/adverse effects ; Recombinant Fusion Proteins/administration & dosage

Real-life experience of luspatercept in transfusion-dependent lower risk myelodysplastic syndrome patients.

Autori: Bouchla A Papageorgiou SG Kotsianidis I a ďalší

Zdroj: British journal of haematology [Br J Haematol] 2025 Jul; Vol. 207 (1), pp. 101-109. Date of Electronic Publication: 2025 May 05.

Spôsob vydávania: Journal Article; Multicenter Study

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myelodysplastic Syndromes*/therapy , Myelodysplastic Syndromes*/mortality , Myelodysplastic Syndromes*/drug therapy , Recombinant Fusion Proteins*/therapeutic use , Recombinant Fusion Proteins*/adverse effects , Recombinant Fusion Proteins*/administration & dosage , Immunoglobulin Fc Fragments*/therapeutic use , Immunoglobulin Fc Fragments*/adverse effects , Immunoglobulin Fc Fragments*/administration & dosage , Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage , Blood Transfusion*, Humans ; Male ; Female ; Aged ; Retrospective Studies ; Middle Aged ; Aged, 80 and over ; Adult ; Treatment Outcome

Coordinated expression of BMP10/ALK1/endoglin-proteins that drive embryonic cardiac and vascular morphogenesis-in patients with heart failure: The EMPEROR Program.

Autori: Packer M Butler J Ferreira JP a ďalší

Zdroj: European journal of heart failure [Eur J Heart Fail] 2025 Sep; Vol. 27 (9), pp. 1737-1751. Date of Electronic Publication: 2025 Jul 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Country of Publication: England NLM ID: 100887595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0844 (Electronic) Linking ISSN: 13889842 NLM ISO Abbreviation: Eur J Heart Fail Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endoglin*/blood , Endoglin*/biosynthesis , Heart Failure*/blood , Heart Failure*/metabolism , Bone Morphogenetic Proteins*/blood , Bone Morphogenetic Proteins*/biosynthesis , Activin Receptors, Type II*/blood , Heart*/embryology , Activin Receptors, Type I*/blood, Humans ; Female ; Male ; Middle Aged ; Aged ; Morphogenesis ; Biomarkers/blood

How to use luspatercept and erythropoiesis-stimulating agents in low-risk myelodysplastic syndrome.

Autori: Santini V Consagra A

Zdroj: British journal of haematology [Br J Haematol] 2025 Jul; Vol. 207 (1), pp. 15-26. Date of Electronic Publication: 2025 May 02.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/complications , Hematinics*/therapeutic use , Recombinant Fusion Proteins*/therapeutic use , Activin Receptors, Type II*/therapeutic use , Immunoglobulin Fc Fragments*/therapeutic use , Anemia*/drug therapy , Anemia*/etiology, Humans

ACVR2A facilitates trophoblast cell invasion through TCF7/c-JUN pathway in pre-eclampsia progression.

Autori: Yang S Liu H Hu J a ďalší

Zdroj: ELife [Elife] 2025 May 30; Vol. 14. Date of Electronic Publication: 2025 May 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Výrazy zo slovníka MeSH: Trophoblasts*/physiology , Trophoblasts*/metabolism , Activin Receptors, Type II*/metabolism , Activin Receptors, Type II*/genetics , Pre-Eclampsia*/genetics , Pre-Eclampsia*/pathology , Pre-Eclampsia*/metabolism , Signal Transduction* , Proto-Oncogene Proteins c-jun*/metabolism, Humans ; Female ; Pregnancy ; Cell Line ; Cell Movement ; Cell Proliferation

Long-Term Experience with Luspatercept in Relapsed/Refractory Myelodysplastic Neoplasms: A Chinese Real-World Study.

Autori: Zhang Z Wang L Liu Z a ďalší

Zdroj: Advances in therapy [Adv Ther] 2025 Apr; Vol. 42 (4), pp. 1907-1918. Date of Electronic Publication: 2025 Mar 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE

Výrazy zo slovníka MeSH: Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/mortality , Recombinant Fusion Proteins*/therapeutic use , Recombinant Fusion Proteins*/adverse effects , Recombinant Fusion Proteins*/administration & dosage , Activin Receptors, Type II*/therapeutic use , Activin Receptors, Type II*/administration & dosage , Immunoglobulin Fc Fragments*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Aged ; Retrospective Studies ; Adult ; Aged, 80 and over ; China ; East Asian People

A Combination of Resveratrol and Quercetin Prevents Sarcopenic Obesity: Its Role as a Signaling Inhibitor of Myostatin/ActRIIA and ActRIIB/Smad and as an Enhancer of Insulin Actions.

Autori: Cano-Martínez A Méndez-Castro JA García-Vázquez VE a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 May 21; Vol. 26 (10). Date of Electronic Publication: 2025 May 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Resveratrol*/pharmacology , Myostatin*/metabolism , Quercetin*/pharmacology , Sarcopenia*/metabolism , Sarcopenia*/prevention & control , Sarcopenia*/drug therapy , Obesity*/metabolism , Obesity*/prevention & control , Obesity*/drug therapy , Insulin*/metabolism , Activin Receptors, Type II*/metabolism, Animals ; Rats ; Male ; Signal Transduction/drug effects ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/drug effects ; Insulin Resistance ; Rats, Wistar ; Smad Proteins/metabolism ; Metabolic Syndrome/metabolism

ACVRL1 variation-induced hereditary hemorrhagic telangiectasia presenting with pulmonary arterial hypertension: clinical and genetic analyses of three case studies.

Autori: Wang Z Li N Qiao N a ďalší

Zdroj: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2025 Apr 09; Vol. 25 (1), pp. 271. Date of Electronic Publication: 2025 Apr 09.

Spôsob vydávania: Journal Article; Case Reports

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE

Výrazy zo slovníka MeSH: Telangiectasia, Hereditary Hemorrhagic*/genetics , Telangiectasia, Hereditary Hemorrhagic*/diagnosis , Telangiectasia, Hereditary Hemorrhagic*/physiopathology , Telangiectasia, Hereditary Hemorrhagic*/complications , Telangiectasia, Hereditary Hemorrhagic*/drug therapy , Pulmonary Arterial Hypertension*/genetics , Pulmonary Arterial Hypertension*/physiopathology , Pulmonary Arterial Hypertension*/drug therapy , Pulmonary Arterial Hypertension*/diagnosis , Activin Receptors, Type II*/genetics , Mutation* , Arterial Pressure*/drug effects , Arterial Pressure*/genetics, Humans ; Female ; Adult ; Phenotype ; Genetic Predisposition to Disease ; Retrospective Studies ; Antihypertensive Agents/therapeutic use

ActRII or BMPR ligands inhibit skeletal myoblast differentiation, and BMPs promote heterotopic ossification in skeletal muscles in mice.

Autori: Egerman MA Zhang Y Donne R a ďalší

Zdroj: Skeletal muscle [Skelet Muscle] 2025 Feb 24; Vol. 15 (1), pp. 4. Date of Electronic Publication: 2025 Feb 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101561193 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5040 (Electronic) Linking ISSN: 20445040 NLM ISO Abbreviation: Skelet Muscle Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cell Differentiation* , Activin Receptors, Type II*/metabolism , Activin Receptors, Type II*/genetics , Ossification, Heterotopic*/metabolism , Ossification, Heterotopic*/genetics , Ossification, Heterotopic*/pathology , Muscle, Skeletal*/metabolism , Muscle, Skeletal*/pathology , Myoblasts, Skeletal*/metabolism , Bone Morphogenetic Protein Receptors*/metabolism , Bone Morphogenetic Proteins*/metabolism , Bone Morphogenetic Proteins*/genetics, Animals ; Humans ; Mice ; Ligands ; Signal Transduction ; Muscle Development ; Mice, Inbred C57BL ; Bone Morphogenetic Protein 7/metabolism ; Bone Morphogenetic Protein 7/genetics