Výsledky vyhľadávania - "Abecasis, G."

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Autori: Zanoni, P. Khetarpal, S. A. Larach, D. B. a ďalší

Dostupnosť: http://hdl.handle.net/10150/623258
http://arizona.openrepository.com/arizona/handle/10150/623258

Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis

Autori: Zhou, S. R. Sosina, O. A. Bovijn, J. a ďalší

Zdroj: Nature Genetics. 55(8):1277-87

Predmety: Medical Genetics and Genomics, Medicinsk genetik och genomik, cell-adhesion molecule-1, mendelian randomization, bone mass, identification, determinants, instruments, ultrasound, expression, heel, gwas, Genetics & Heredity

Prístupová URL adresa: https://gup.ub.gu.se/publication/328775

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Autori: Mahajan, A. Spracklen, C.N. Zhang, W. a ďalší

Prispievatelia: Mahajan, A. Spracklen, C.N. Zhang, W. a ďalší

Zdroj: Nat Genet
Mahajan, A, Spracklen, C N, Zhang, W, Ng, M C Y, Petty, L E, Kitajima, H, Yu, G Z, Rüeger, S, Speidel, L, Kim, Y J, Horikoshi, M, Mercader, J M, Taliun, D, Moon, S, Kwak, S-H, Robertson, N R, Rayner, N W, Loh, M, Kim, B-J, Chiou, J, Miguel-Escalada, I, Della Briotta Parolo, P, Lin, K, Bragg, F, Preuss, M H, Takeuchi, F, Nano, J, Guo, X, Lamri, A, Nakatochi, M, Scott, R A, Lee, J-J, Huerta-Chagoya, A, Graff, M, Chai, J-F, Parra, E J, Yao, J, Bielak, L F, Tabara, Y, Hai, Y, Steinthorsdottir, V, Cook, J P, Kals, M, Grarup, N, Schmidt, E M, Pan, I, Sofer, T, Wuttke, M, Sarnowski, C, Gieger, C, Nousome, D, Trompet, S, Long, J, Sun, M, Tong, L, Chen, W-M, Ahmad, M, Noordam, R, Lim, V J Y, Tam, C H T, Joo, Y Y, Chen, C-H, Raffield, L M, Lecoeur, C, Prins, B P, Nicolas, A, Yanek, L R, Chen, G, Jensen, R A, Tajuddin, S, Kabagambe, E K, An, P, Xiang, A H, Choi, H S, Cade, B E, Tan, J, Flanagan, J, Abaitua, F, Adair, L S, Adeyemo, A, Aguilar-Salinas, C A, Akiyama, M, Anand, S S, Bertoni, A, Bian, Z, Bork-Jensen, J, Brandslund, I, Brody, J A, Brummett, C M, Buchanan, T A, Canouil, M, Chan, J C N, Chang, L-C, Chee, M-L, Chen, J, Chen, S-H, Chen, Y-T, Chen, Z, Chuang, L-M, Cushman, M, Das, S K, de Silva, H J, Dedoussis, G, Dimitrov, L, Doumatey, A P, Du, S, Duan, Q, Eckardt, K-U, Emery, L S, Evans, D S, Evans, M K, Fischer, K, Floyd, J S, Ford, I, Fornage, M, Franco, O H, Frayling, T M, Freedman, B I, Fuchsberger, C, Genter, P, Gerstein, H C, Giedraitis, V, González-Villalpando, C, González-Villalpando, M E, Goodarzi, M O, Gordon-Larsen, P, Gorkin, D, Gross, M, Guo, Y, Hackinger, S, Han, S, Hattersley, A T, Herder, C, Howard, A-G, Hsueh, W, Huang, M, Huang, W, Hung, Y-J, Hwang, M Y, Hwu, C-M, Ichihara, S, Ikram, M A, Ingelsson, M, Islam, M T, Isono, M, Jang, H-M, Jasmine, F, Jiang, G, Jonas, J B, Jørgensen, M E, Jørgensen, T, Kamatani, Y, Kandeel, F R, Kasturiratne, A, Katsuya, T, Kaur, V, Kawaguchi, T, Keaton, J M, Kho, A N, Khor, C-C, Kibriya, M G, Kim, D-H, Kohara, K, Kriebel, J, Kronenberg, F, Kuusisto, J, Läll, K, Lange, L A, Lee, M-S, Lee, N R, Leong, A, Li, L, Li, Y, Li-Gao, R, Ligthart, S, Lindgren, C M, Linneberg, A, Liu, C-T, Liu, J, Locke, A E, Louie, T, Luan, J, Luk, A O, Luo, X, Lv, J, Lyssenko, V, Mamakou, V, Mani, K R, Meitinger, T, Metspalu, A, Morris, A D, Nadkarni, G N, Nadler, J L, Nalls, M A, Nayak, U, Nongmaithem, S S, Ntalla, I, Okada, Y, Orozco, L, Patel, S R, Pereira, M A, Peters, A, Pirie, F J, Porneala, B, Prasad, G, Preissl, S, Rasmussen-Torvik, L J, Reiner, A P, Roden, M, Rohde, R, Roll, K, Sabanayagam, C, Sander, M, Sandow, K, Sattar, N, Schönherr, S, Schurmann, C, Shahriar, M, Shi, J, Shin, D M, Shriner, D, Smith, J A, So, W Y, Stančáková, A, Stilp, A M, Strauch, K, Suzuki, K, Takahashi, A, Taylor, K D, Thorand, B, Thorleifsson, G, Thorsteinsdottir, U, Tomlinson, B, Torres, J M, Tsai, F-J, Tuomilehto, J, Tusie-Luna, T, Udler, M S, Valladares-Salgado, A, van Dam, R M, van Klinken, J B, Varma, R, Vujkovic, M, Wacher-Rodarte, N, Wheeler, E, Whitsel, E A, Wickremasinghe, A R, van Dijk, K W, Witte, D R, Yajnik, C S, Yamamoto, K, Yamauchi, T, Yengo, L, Yoon, K, Yu, C, Yuan, J-M, Yusuf, S, Zhang, L, Zheng, W, Raffel, L J, Igase, M, Ipp, E, Redline, S, Cho, Y S, Lind, L, Province, M A, Hanis, C L, Peyser, P A, Ingelsson, E, Zonderman, A B, Psaty, B M, Wang, Y-X, Rotimi, C N, Becker, D M, Matsuda, F, Liu, Y, Zeggini, E, Yokota, M, Rich, S S, Kooperberg, C, Pankow, J S, Engert, J C, Chen, Y-D I, Froguel, P, Wilson, J G, Sheu, W H H, Kardia, S L R, Wu, J-Y, Hayes, M G, Ma, R C W, Wong, T-Y, Groop, L, Mook-Kanamori, D O, Chandak, G R, Collins, F S, Bharadwaj, D, Paré, G, Sale, M M, Ahsan, H, Motala, A A, Shu, X-O, Park, K-S, Jukema, J W, Cruz, M, McKean-Cowdin, R, Grallert, H, Cheng, C-Y, Bottinger, E P, Dehghan, A, Tai, E-S, Dupuis, J, Kato, N, Laakso, M, Köttgen, A, Koh, W-P, Palmer, C N A, Liu, S, Abecasis, G, Kooner, J S, Loos, R J F, North, K E, Haiman, C A, Florez, J C, Saleheen, D, Hansen, T, Pedersen, O, Mägi, R, Langenberg, C, Wareham, N J, Maeda, S, Kadowaki, T, Lee, J, Millwood, I Y, Walters, R G, Stefansson, K, Myers, S R, Ferrer, J, Gaulton, K J, Meigs, J B, Mohlke, K L, Gloyn, A L, Bowden, D W, Below, J E, Chambers, J C, Sim, X, Boehnke, M, Rotter, J I, McCarthy, M I, Morris, A P, FinnGen & eMERGE Consortium 2022, 'Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation', Nature Genetics, vol. 54, no. 5, pp. 560-572. https://doi.org/10.1038/s41588-022-01058-3
Mahajan, A, Spracklen, C N, Zhang, W, Ng, M C Y, Petty, L E, Kitajima, H, Yu, G Z, Rüeger, S, Speidel, L, Kim, Y J, Horikoshi, M, Mercader, J M, Taliun, D, Moon, S, Kwak, S-H, Robertson, N R, Rayner, N W, Loh, M, Kim, B-J, Chiou, J, Miguel-Escalada, I, Della Briotta Parolo, P, Lin, K, Bragg, F, Preuss, M H, Takeuchi, F, Nano, J, Guo, X, Lamri, A, Nakatochi, M, Scott, R A, Lee, J-J, Huerta-Chagoya, A, Graff, M, Chai, J-F, Parra, E J, Yao, J, Bielak, L F, Grarup, N, Chen, W-M, Bork-Jensen, J, Islam, M T, Jørgensen, M E, Jørgensen, T, Linneberg, A, Witte, D R, Lind, L, Loos, R J F, Hansen, T, Pedersen, O & FinnGen 2022, ' Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation ', Nature Genetics, vol. 54, no. 5, pp. 560-572 . https://doi.org/10.1038/s41588-022-01058-3
2022, ' Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation ', Nature Genetics, vol. 54, no. 5, pp. 560-572 . https://doi.org/10.1038/s41588-022-01058-3
Nat. Genet. 54, 560-572 (2022)
Mahajan, A, Spracklen, C N, Zhang, W, Ng, M C Y, Petty, L E, Kitajima, H, Yu, G Z, Rüeger, S, Speidel, L, Kim, Y J, Horikoshi, M, Mercader, J M, Taliun, D, Moon, S, Kwak, S, Robertson, N R, Rayner, N W, Loh, M, Kim, B, Chiou, J, Miguel-escalada, I, Della Briotta Parolo, P, Lin, K, Bragg, F, Preuss, M H, Takeuchi, F, Nano, J, Guo, X, Lamri, A, Nakatochi, M, Scott, R A, Lee, J, Huerta-chagoya, A, Graff, M, Chai, J, Parra, E J, Yao, J, Bielak, L F, Tabara, Y, Hai, Y, Steinthorsdottir, V, Cook, J P, Kals, M, Grarup, N, Schmidt, E M, Pan, I, Sofer, T, Wuttke, M, Sarnowski, C, Gieger, C, Nousome, D, Trompet, S, Long, J, Sun, M, Tong, L, Chen, W, Ahmad, M, Noordam, R, Lim, V J Y, Tam, C H T, Joo, Y Y, Chen, C, Raffield, L M, Lecoeur, C, Prins, B P, Nicolas, A, Yanek, L R, Chen, G, Jensen, R A, Tajuddin, S, Kabagambe, E K, An, P, Xiang, A H, Choi, H S, Cade, B E, Tan, J, Flanagan, J, Abaitua, F, Adair, L S, Adeyemo, A, Aguilar-salinas, C A, Akiyama, M, Anand, S S, Bertoni, A, Bian, Z, Bork-jensen, J, Brandslund, I, Brody, J A, Brummett, C M, Buchanan, T A, Canouil, M, Chan, J C N, Chang, L, Chee, M, Chen, J, Chen, S, Chen, Y, Chen, Z, Chuang, L, Cushman, M, Das, S K, De Silva, H J, Dedoussis, G, Dimitrov, L, Doumatey, A P, Du, S, Duan, Q, Eckardt, K, Emery, L S, Evans, D S, Evans, M K, Fischer, K, Floyd, J S, Ford, I, Fornage, M, Franco, O H, Frayling, T M, Freedman, B I, Fuchsberger, C, Genter, P, Gerstein, H C, Giedraitis, V, González-villalpando, C, González-villalpando, M E, Goodarzi, M O, Gordon-larsen, P, Gorkin, D, Gross, M, Guo, Y, Hackinger, S, Han, S, Hattersley, A T, Herder, C, Howard, A, Hsueh, W, Huang, M, Huang, W, Hung, Y, Hwang, M Y, Hwu, C, Ichihara, S, Ikram, M A, Ingelsson, M, Islam, M T, Isono, M, Jang, H, Jasmine, F, Jiang, G, Jonas, J B, Jørgensen, M E, Jørgensen, T, Kamatani, Y, Kandeel, F R, Kasturiratne, A, Katsuya, T, Kaur, V, Kawaguchi, T, Keaton, J M, Kho, A N, Khor, C, Kibriya, M G, Kim, D, Kohara, K, Kriebel, J, Kronenberg, F, Kuusisto, J, Läll, K, Lange, L A, Lee, M, Lee, N R, Leong, A, Li, L, Li, Y, Li-gao, R, Ligthart, S, Lindgren, C M, Linneberg, A, Liu, C, Liu, J, Locke, A E, Louie, T, Luan, J, Luk, A O, Luo, X, Lv, J, Lyssenko, V, Mamakou, V, Mani, K R, Meitinger, T, Metspalu, A, Morris, A D, Nadkarni, G N, Nadler, J L, Nalls, M A, Nayak, U, Nongmaithem, S S, Ntalla, I, Okada, Y, Orozco, L, Patel, S R, Pereira, M A, Peters, A, Pirie, F J, Porneala, B, Prasad, G, Preissl, S, Rasmussen-torvik, L J, Reiner, A P, Roden, M, Rohde, R, Roll, K, Sabanayagam, C, Sander, M, Sandow, K, Sattar, N, Schönherr, S, Schurmann, C, Shahriar, M, Shi, J, Shin, D M, Shriner, D, Smith, J A, So, W Y, Stančáková, A, Stilp, A M, Strauch, K, Suzuki, K, Takahashi, A, Taylor, K D, Thorand, B, Thorleifsson, G, Thorsteinsdottir, U, Tomlinson, B, Torres, J M, Tsai, F, Tuomilehto, J, Tusie-luna, T, Udler, M S, Valladares-salgado, A, Van Dam, R M, Van Klinken, J B, Varma, R, Vujkovic, M, Wacher-rodarte, N, Wheeler, E, Whitsel, E A, Wickremasinghe, A R, Van Dijk, K W, Witte, D R, Yajnik, C S, Yamamoto, K, Yamauchi, T, Yengo, L, Yoon, K, Yu, C, Yuan, J, Yusuf, S, Zhang, L, Zheng, W, Rüeger, S, Della Briotta Parolo, P, Joo, Y Y, Hayes, M G, Raffel, L J, Igase, M, Ipp, E, Redline, S, Cho, Y S, Lind, L, Province, M A, Hanis, C L, Peyser, P A, Ingelsson, E, Zonderman, A B, Psaty, B M, Wang, Y, Rotimi, C N, Becker, D M, Matsuda, F, Liu, Y, Zeggini, E, Yokota, M, Rich, S S, Kooperberg, C, Pankow, J S, Engert, J C, Chen, Y I, Froguel, P, Wilson, J G, Sheu, W H H, Kardia, S L R, Wu, J, Hayes, M G, Ma, R C W, Wong, T, Groop, L, Mook-kanamori, D O, Chandak, G R, Collins, F S, Bharadwaj, D, Paré, G, Sale, M M, Ahsan, H, Motala, A A, Shu, X, Park, K, Jukema, J W, Cruz, M, Mckean-cowdin, R, Grallert, H, Cheng, C, Bottinger, E P, Dehghan, A, Tai, E, Dupuis, J, Kato, N, Laakso, M, Köttgen, A, Koh, W, Palmer, C N A, Liu, S, Abecasis, G, Kooner, J S, Loos, R J F, North, K E, Haiman, C A, Florez, J C, Saleheen, D, Hansen, T, Pedersen, O, Mägi, R, Langenberg, C, Wareham, N J, Maeda, S, Kadowaki, T, Lee, J, Millwood, I Y, Walters, R G, Stefansson, K, Myers, S R, Ferrer, J, Gaulton, K J, Meigs, J B, Mohlke, K L, Gloyn, A L, Bowden, D W, Below, J E, Chambers, J C, Sim, X, Boehnke, M, Rotter, J I, Mccarthy, M I & Morris, A P 2022, 'Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation', Nature Genetics, vol. 54, no. 5, pp. 560-572. https://doi.org/10.1038/s41588-022-01058-3
Nature Genetics, vol 54, iss 5
Mahajan, A, Spracklen, C N, Zhang, W, Ng, M C Y, Petty, L E, Kitajima, H, Yu, G Z, Rüeger, S, Speidel, L, Kim, Y J, Horikoshi, M, Mercader, J M, Taliun, D, Moon, S, Kwak, S H, Robertson, N R, Rayner, N W, Loh, M, Kim, B J, Chiou, J, Miguel-Escalada, I, della Briotta Parolo, P, Lin, K, Bragg, F, Preuss, M H, Takeuchi, F, Nano, J, Guo, X, Lamri, A, Nakatochi, M, Scott, R A, Lee, J J, Huerta-Chagoya, A, Graff, M, Chai, J F, Parra, E J, Yao, J, Bielak, L F, Tabara, Y, Grarup, N, Chen, W M, Jensen, R A, Chen, J, Huang, W, Jørgensen, M E, Jørgensen, T, Witte, D R, Zhang, L, Hansen, T, Pedersen, O, FinnGen & eMERGE Consortium 2022, 'Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation', Nature Genetics, vol. 54, no. 5, pp. 560-572. https://doi.org/10.1038/s41588-022-01058-3

Predmety: 0301 basic medicine, name=Genetics, Hasso-Plattner-Institut für Digital Engineering gGmbH, eMERGE Consortium, Medical and Health Sciences, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Risk Factors, Genetics, Diabetes Mellitus, Ethnicity, Humans, Genetic Predisposition to Disease, Polymorphism, Type 2/epidemiology, Metabolic and endocrine, ddc:610, 0303 health sciences, Diabetes, Human Genome, Single Nucleotide, Biological Sciences, Polymorphism, Single Nucleotide/genetics, R1, 3. Good health, FinnGen, [SDV] Life Sciences [q-bio], Diabetes Mellitus, Type 2/epidemiology, Diabetes Mellitus, Type 2, Single Nucleotide/genetics, Type 2, Developmental Biology, Genome-Wide Association Study

Popis súboru: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35551307
https://eprints.gla.ac.uk/271636/1/271636.pdf
https://hdl.handle.net/1887/3479795
https://pure.amsterdamumc.nl/en/publications/9f15452f-a5dd-480c-babc-ac5f9b81c476
https://doi.org/10.1038/s41588-022-01058-3
https://pergamos.lib.uoa.gr/uoa/dl/object/3346931
https://curis.ku.dk/ws/files/362320626/Multi_ancestry_genetic_study_of_type_2_diabetes_highlights_the_power_of_diverse_populations_for_discovery_and_translation.pdf
https://hdl.handle.net/20.500.11820/9676888f-1f60-44ff-8c62-09196c2c8dee
https://www.pure.ed.ac.uk/ws/files/266903807/Multi_ancestry_genetic_study_of_type_2_diabetes_highlights_the_power_of_diverse_populations_for_discovery_and_translation.pdf
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=65002
https://discovery-pp.ucl.ac.uk/id/eprint/10155438/
https://escholarship.org/uc/item/59z0821f
https://pure.au.dk/portal/en/publications/04d034b2-c833-41e4-8665-f9fb146b8f52
https://doi.org/10.1038/s41588-022-01058-3
http://www.scopus.com/inward/record.url?scp=85130637871&partnerID=8YFLogxK
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9179018/pdf/nihms-1792335.pdf

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Autori: Ramdas, S. Judd, J. Graham, S. E. a ďalší

Zdroj: American Journal of Human Genetics. 109(8):1366-1387

Predmety: Genetics and Genomics, Genetik och genomik, integrative analysis, wide association, 3d genome, variants, cholesterol, annotation, obesity, common, loci, expression, Genetics & Heredity

Prístupová URL adresa: https://gup.ub.gu.se/publication/318991

A deep catalogue of protein-coding variation in 983,578 individuals

Autori: Sun, KY Bai, X Chen, S a ďalší

Relation: http://hdl.handle.net/11343/349714

Dostupnosť: http://hdl.handle.net/11343/349714

Predicting physiological aging rates from a range of quantitative traits using machine learning

Autori: Sun E. D. Qian Y. Oppong R. a ďalší

Zdroj: Aging (Albany NY)

Predmety: Adult, Aged, 80 and over, Male, Neuroticism, 0301 basic medicine, Aging, aging clock, machine learning, mortality, personalized medicine, physiological aging rate, quantitative trait, DNA Methylation, Middle Aged, Pulse Wave Analysis, Models, Biological, Machine Learning, Young Adult, 03 medical and health sciences, Phenotype, Humans, Female, Longitudinal Studies, Algorithms, Research Paper, Aged, Genome-Wide Association Study

Prístupová URL adresa: https://www.aging-us.com/article/203660/pdf
https://pubmed.ncbi.nlm.nih.gov/34718232
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8580337/
https://www.aging-us.com/lookup/doi/10.18632/aging.203660
https://hdl.handle.net/11388/346653
https://doi.org/10.18632/aging.203660

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

Autori: Eijsbouts, C. Zheng, T. Kennedy, N. A. a ďalší

Zdroj: Nature Genetics. 53(11):1543-1552

Predmety: Medical Genetics and Genomics, Medicinsk genetik och genomik

Prístupová URL adresa: https://gup.ub.gu.se/publication/315468

Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder

Autori: Jia, X. M. Goes, F. S. Locke, A. E. a ďalší

Zdroj: Molecular Psychiatry. 26(9):5239-5250

Predmety: Psychiatry, Psykiatri, genome-wide association, genetic epidemiology research, spectrum, disorder, african-american, adult health, schizophrenia, variants, burden, individuals, risk, Biochemistry & Molecular Biology, Neurosciences & Neurology

Prístupová URL adresa: https://gup.ub.gu.se/publication/303837

The power of genetic diversity in genome-wide association studies of lipids (vol 600, pg 675, 2021)

Autori: Graham, SE Clarke, SL Wu, K-HH a ďalší

Popis súboru: application/pdf

Prístupová URL adresa: https://hdl.handle.net/1887/3720827

Clonal haematopoiesis and risk of chronic liver disease

Autori: Wong, WJ Emdin, C Bick, AG a ďalší

Predmety: Ageing, Metabolic diseases, Genome-wide association studies, Non-alcoholic steatohepatitis

Prístupová URL adresa: https://discovery-pp.ucl.ac.uk/id/eprint/10191211/

Author Correction: The power of genetic diversity in genome-wide association studies of lipids (Nature, (2021), 600, 7890, (675-679), 10.1038/s41586-021-04064-3)

Autori: Graham, S.E. Clarke, S.L. Wu, K.-H.H. Kanoni, S. Zajac, G.J.M. Ramdas, S. Surakka, I. Ntalla, I. Vedantam, S. Winkler, T.W. Locke, A.E. Marouli, E. Hwang, M.Y. Han, S. Narita, A. Choudhury, A. Bentley, A.R. Ekoru, K. Verma, A. Trivedi, B. Martin, H.C. Hunt, K.A. Hui, Q. Klarin, D. Zhu, X. Thorleifsson, G. Helgadottir, A. Gudbjartsson, D.F. Holm, H. Olafsson, I. Akiyama, M. Sakaue, S. Terao, C. Kanai, M. Zhou, W. Brumpton, B.M. Rasheed, H. Ruotsalainen, S.E. Havulinna, A.S. Veturi, Y. Feng, Q.P. Rosenthal, E.A. Lingren, T. Pacheco, J.A. Pendergrass, S.A. Haessler, J. Giulianini, F. Bradford, Y. Miller, J.E. Campbell, A. Lin, K. Millwood, I.Y. Hindy, G. Rasheed, A. Faul, J.D. Zhao, W. Weir, D.R. Turman, C. Huang, H. Graff, M. Mahajan, A. Brown, M.R. Zhang, W. Yu, K. Schmidt, E.M. Pandit, A. Gustafsson, S. Yin, X. Luan, J. Zhao, J.-H. Matsuda, F. Jang, H.-M. Yoon, K. Medina-Gomez, C. Pitsillides, A. Hottenga, J.J. Willemsen, G. Wood, A.R. Ji, Y. Gao, Z. Haworth, S. Mitchell, R.E. Chai, J.F. Aadahl, M. Yao, J. Manichaikul, A. Warren, H.R. Ramirez, J. Bork-Jensen, J. Kårhus, L.L. Goel, A. Sabater-Lleal, M. Noordam, R. Sidore, C. Fiorillo, E. McDaid, A.F. Marques-Vidal, P. Wielscher, M. Trompet, S. Sattar, N. Møllehave, L.T. Thuesen, B.H. Munz, M. Zeng, L. Huang, J. Yang, B. Poveda, A. Kurbasic, A. Lamina, C. Forer, L. Scholz, M. Galesloot, T.E. Bradfield, J.P. Daw, E.W. Zmuda, J.M. Mitchell, J.S. Fuchsberger, C. Christensen, H. Brody, J.A. Feitosa, M.F. Wojczynski, M.K. Preuss, M. Mangino, M. Christofidou, P. Verweij, N. Benjamins, J.W. Engmann, J. Kember, R.L. Slieker, R.C. Lo, K.S. Zilhao, N.R. Le, P. Kleber, M.E. Delgado, G.E. Huo, S. Ikeda, D.D. Iha, H. Yang, J. Liu, J. Leonard, H.L. Marten, J. Schmidt, B. Arendt, M. Smyth, L.J. Cañadas-Garre, M. Wang, C. Nakatochi, M. Wong, A. Hutri-Kähönen, N. Sim, X. Xia, R. Huerta-Chagoya, A. Fernandez-Lopez, J.C. Lyssenko, V. Ahmed, M. Jackson, A.U. Yousri, N.A. Irvin, M.R. Oldmeadow, C. Kim, H.-N. Ryu, S. Timmers, P.R.H.J. Arbeeva, L. Dorajoo, R. Lange, L.A. Chai, X. Prasad, G. Lorés-Motta, L. Pauper, M. Long, J. Li, X. Theusch, E. Takeuchi, F. Spracklen, C.N. Loukola, A. Bollepalli, S. Warner, S.C. Wang, Y.X. Wei, W.B. Nutile, T. Ruggiero, D. Sung, Y.J. Hung, Y.-J. Chen, S. Liu, F. Yang, J. Kentistou, K.A. Gorski, M. Brumat, M. Meidtner, K. Bielak, L.F. Smith, J.A. Hebbar, P. Farmaki, A.-E. Hofer, E. Lin, M. Xue, C. Zhang, J. Concas, M.P. Vaccargiu, S. van der Most, P.J. Pitkänen, N. Cade, B.E. Lee, J. van der Laan, S.W. Chitrala, K.N. Weiss, S. Zimmermann, M.E. Lee, J.Y. Choi, H.S. Nethander, M. Freitag-Wolf, S. Southam, L. Rayner, N.W. Wang, C.A. Lin, S.-Y. Wang, J.-S. Couture, C. Lyytikäinen, L.-P. Nikus, K. Cuellar-Partida, G. Vestergaard, H. Hildalgo, B. Giannakopoulou, O. Cai, Q. Obura, M.O. van Setten, J. Li, X. Schwander, K. Terzikhan, N. Shin, J.H. Jackson, R.D. Reiner, A.P. Martin, L.W. Chen, Z. Li, L. Highland, H.M. Young, K.L. Kawaguchi, T. Thiery, J. Bis, J.C. Nadkarni, G.N. Launer, L.J. Li, H. Nalls, M.A. Raitakari, O.T. Ichihara, S. Wild, S.H. Nelson, C.P. Campbell, H. Jäger, S. Nabika, T. Al-Mulla, F. Niinikoski, H. Braund, P.S. Kolcic, I. Kovacs, P. Giardoglou, T. Katsuya, T. Bhatti, K.F. de Kleijn, D. de Borst, G.J. Kim, E.K. Adams, H.H.H. Ikram, M.A. Zhu, X. Asselbergs, F.W. Kraaijeveld, A.O. Beulens, J.W.J. Shu, X.-O. Rallidis, L.S. Pedersen, O. Hansen, T. Mitchell, P. Hewitt, A.W. Kähönen, M. Pérusse, L. Bouchard, C. Tönjes, A. Chen, Y.-D.I. Pennell, C.E. Mori, T.A. Lieb, W. Franke, A. Ohlsson, C. Mellström, D. Cho, Y.S. Lee, H. Yuan, J.-M. Koh, W.-P. Rhee, S.Y. Woo, J.-T. Heid, I.M. Stark, K.J. Völzke, H. Homuth, G. Evans, M.K. Zonderman, A.B. Polasek, O. Pasterkamp, G. Hoefer, I.E. Redline, S. Pahkala, K. Oldehinkel, A.J. Snieder, H. Biino, G. Schmidt, R. Schmidt, H. Chen, Y.E. Bandinelli, S. Dedoussis, G. Thanaraj, T.A. Kardia, S.L.R. Kato, N. Schulze, M.B. Girotto, G. Jung, B. Böger, C.A. Joshi, P.K. Bennett, D.A. De Jager, P.L. Lu, X. Mamakou, V. Brown, M. Caulfield, M.J. Munroe, P.B. Guo, X. Ciullo, M. Jonas, J.B. Samani, N.J. Kaprio, J. Pajukanta, P. Adair, L.S. Bechayda, S.A. de Silva, H.J. Wickremasinghe, A.R. Krauss, R.M. Wu, J.-Y. Zheng, W. den Hollander, A.I. Bharadwaj, D. Correa, A. Wilson, J.G. Lind, L. Heng, C.-K. Nelson, A.E. Golightly, Y.M. Wilson, J.F. Penninx, B. Kim, H.-L. Attia, J. Scott, R.J. Rao, D.C. Arnett, D.K. Hunt, S.C. Walker, M. Koistinen, H.A. Chandak, G.R. Yajnik, C.S. Mercader, J.M. Tusié-Luna, T. Aguilar-Salinas, C.A. Villalpando, C.G. Orozco, L. Fornage, M. Tai, E.S. van Dam, R.M. Lehtimäki, T. Chaturvedi, N. Yokota, M. Liu, J. Reilly, D.F. McKnight, A.J. Kee, F. Jöckel, K.-H. McCarthy, M.I. Palmer, C.N.A. Vitart, V. Hayward, C. Simonsick, E. van Duijn, C.M. Lu, F. Qu, J. Hishigaki, H. Lin, X. März, W. Parra, E.J. Cruz, M. Gudnason, V. Tardif, J.-C. Lettre, G. ’t Hart, L.M. Elders, P.J.M. Damrauer, S.M. Kumari, M. Kivimaki, M. van der Harst, P. Spector, T.D. Loos, R.J.F. Province, M.A. Psaty, B.M. Brandslund, I. Pramstaller, P.P. Christensen, K. Ripatti, S. Widén, E. Hakonarson, H. Grant, S.F.A. Kiemeney, L.A.L.M. de Graaf, J. Loeffler, M. Kronenberg, F. Gu, D. Erdmann, J. Schunkert, H. Franks, P.W. Linneberg, A. Jukema, J.W. Khera, A.V. Männikkö, M. Jarvelin, M.-R. Kutalik, Z. Cucca, F. Mook-Kanamori, D.O. van Dijk, K.W. Watkins, H. Strachan, D.P. Grarup, N. Sever, P. Poulter, N. Rotter, J.I. Dantoft, T.M. Karpe, F. Neville, M.J. Timpson, N.J. Cheng, C.-Y. Wong, T.-Y. Khor, C.C. Sabanayagam, C. Peters, A. Gieger, C. Hattersley, A.T. Pedersen, N.L. Magnusson, P.K.E. Boomsma, D.I. de Geus, E.J.C. Cupples, L.A. van Meurs, J.B.J. Ghanbari, M. Gordon-Larsen, P. Huang, W. Kim, Y.J. Tabara, Y. Wareham, N.J. Langenberg, C. Zeggini, E. Kuusisto, J. Laakso, M. Ingelsson, E. Abecasis, G. Chambers, J.C. Kooner, J.S. de Vries, P.S. Morrison, A.C. North, K.E. Daviglus, M. Kraft, P. Martin, N.G. Whitfield, J.B. Abbas, S. Saleheen, D. Walters, R.G. Holmes, M.V. Black, C. Smith, B.H. Justice, A.E. Baras, A. Buring, J.E. Ridker, P.M. Chasman, D.I. Kooperberg, C. Wei, W.-Q. Jarvik, G.P. Namjou, B. Hayes, M.G. Ritchie, M.D. Jousilahti, P. Salomaa, V. Hveem, K. Åsvold, B.O. Kubo, M. Kamatani, Y. Okada, Y. Murakami, Y. Thorsteinsdottir, U. Stefansson, K. Ho, Y.-L. Lynch, J.A. Rader, D.J. Tsao, P.S. Chang, K.-M. Cho, K. O’Donnell, C.J. Gaziano, J.M. Wilson, P. Rotimi, C.N. Hazelhurst, S. Ramsay, M. Trembath, R.C. van Heel, D.A. Tamiya, G. Yamamoto, M. Kim, B.-J. Mohlke, K.L. Frayling, T.M. Hirschhorn, J.N. Kathiresan, S. Boehnke, M. Natarajan, P. Peloso, G.M. Brown, C.D. Morris, A.P. Assimes, T.L. Deloukas, P. Sun, Y.V. Willer, C.J. VA Million Veteran Program Global Lipids Genetics Consortium

Predmety: 3. Good health

Prístupová URL adresa: https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3342972

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization

Autori: Willems SM Ng NHJ Fernandez J a ďalší

Zdroj: Wellcome Open Research, 2023

Popis súboru: application/pdf

Relation: https://eprints.ncl.ac.uk/301452; https://eprints.ncl.ac.uk/fulltext.aspx?url=301452/E412AEE3-26F2-446F-BA3F-9F71260E1945.pdf&pub_id=301452

Dostupnosť: https://eprints.ncl.ac.uk/301452

Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Autori: Ziyatdinov, A Torres, J Alegre-Díaz, J a ďalší

Prispievatelia: Ziyatdinov, A Torres, J Alegre-Díaz, J a ďalší

Dostupnosť: https://doi.org/10.1038/s41586-023-06595-3
https://ora.ox.ac.uk/objects/uuid:f8100a6c-153a-4bfb-af57-4c1bd90a0afe

Methods for fine mapping complex traits in human pedigrees

Autori: Abecasis, G. R.

Predmety: 572.8, Genetic disorders, Disease genes

Dostupnosť: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365700

Whole-genome sequencing reveals host factors underlying critical COVID-19

Autori: Kousathanas A. Pairo-Castineira E. Rawlik K. a ďalší

Prispievatelia: Kousathanas A. Pairo-Castineira E. Rawlik K. a ďalší

Relation: info:eu-repo/semantics/altIdentifier/pmid/35255492; info:eu-repo/semantics/altIdentifier/wos/WOS:000812472400001; volume:607; issue:7917; firstpage:97; lastpage:103; journal:NATURE; https://hdl.handle.net/11380/1294474

Dostupnosť: https://hdl.handle.net/11380/1294474
https://doi.org/10.1038/s41586-022-04576-6

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Autori: Justice, A.E. Karaderi, T. Highland, H.M. a ďalší

Prispievatelia: Justice, A.E. Karaderi, T. Highland, H.M. a ďalší

Predmety: Animals, Body Fat Distribution/methods, Body Mass Index, Case-Control Studies, Drosophila/genetics, Exome/genetics, Female, Gene Frequency/genetics, Genetic Predisposition to Disease/genetics, Genetic Variation/genetics, Genome-Wide Association Study/methods, Homeostasis/genetics, Humans, Lipids/genetics, Male, Proteins/genetics, Risk Factors, Waist-Hip Ratio/methods

Popis súboru: application/pdf

Relation: Nature Genetics; https://iris.unil.ch/handle/iris/74577; serval:BIB_3FE73F14651D; 000459947200014

Dostupnosť: https://iris.unil.ch/handle/iris/74577
https://doi.org/10.1038/s41588-018-0334-2

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Autori: Turcot, V. Lu, Y. Highland, H.M. a ďalší

Prispievatelia: Turcot, V. Lu, Y. Highland, H.M. a ďalší

Predmety: Adult, Animals, Body Mass Index, Drosophila/genetics, Energy Intake/genetics, Energy Metabolism/genetics, Female, Gene Frequency, Genetic Variation, Humans, Male, Obesity/genetics, Proteins/genetics, Syndrome

Popis súboru: application/pdf

Relation: Nature Genetics; https://iris.unil.ch/handle/iris/60982; serval:BIB_37FAA1DECECC; 000423157400007

Dostupnosť: https://iris.unil.ch/handle/iris/60982
https://doi.org/10.1038/s41588-017-0011-x

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

Autori: Wheeler, E. Leong, A. Liu, C.T. a ďalší

Prispievatelia: Wheeler, E. Leong, A. Liu, C.T. a ďalší

Predmety: Diabetes Mellitus, Type 2/diagnosis, Type 2/epidemiology, Type 2/genetics, Genetic Variation, Genome-Wide Association Study, Hemoglobin A, Glycosylated/genetics, Glycosylated/metabolism, Humans, Phenotype, Risk

Popis súboru: application/pdf

Relation: PLoS Medicine; https://iris.unil.ch/handle/iris/259837; serval:BIB_F9F443A70DAC; 000411970300003

Dostupnosť: https://iris.unil.ch/handle/iris/259837
https://doi.org/10.1371/journal.pmed.1002383

Rare and low-frequency coding variants alter human adult height.

Autori: Marouli, E. Graff, M. Medina-Gomez, C. a ďalší

Prispievatelia: Marouli, E. Graff, M. Medina-Gomez, C. a ďalší

Popis súboru: application/pdf

Relation: Nature; https://iris.unil.ch/handle/iris/205749; serval:BIB_CB04B9543EC2; 000393737500031

Dostupnosť: https://iris.unil.ch/handle/iris/205749
https://doi.org/10.1038/nature21039

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Autori: Wain, L.V. Vaez, A. Jansen, R. a ďalší

Predmety: GWAS, blood pressure, cardiovascular risk, complex traits, eSNP, hypertension

Relation: Hypertension; https://iris.unil.ch/handle/iris/121680; serval:BIB_324C28AFCA02; 000407241500001

Dostupnosť: https://iris.unil.ch/handle/iris/121680
https://doi.org/10.1161/HYPERTENSIONAHA.117.09438