Suchergebnisse - "ATP Binding Cassette Transporter 1"

Roles of ABCA1 in Chronic Obstructive Pulmonary Disease.

Autoren: Gu Y Bi X Liu X et al.

Quelle: COPD [COPD] 2025 Dec; Vol. 22 (1), pp. 2493701. Date of Electronic Publication: 2025 Apr 29.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101211769 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-2563 (Electronic) Linking ISSN: 15412563 NLM ISO Abbreviation: COPD Subsets: MEDLINE

MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/metabolism , ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/physiology, Humans ; Signal Transduction ; Cholesterol/metabolism ; Lipid Metabolism ; Apoptosis ; Inflammation/metabolism ; Animals

Synthesis and evaluation of 5, 6-dihydro-8 H -isoquinolino[1, 2- b ]quinazolin-8-one derivatives as novel non-lipogenic ABCA1 up-regulators with inhibitory effects on macrophage-derived foam cell formation.

Autoren: Yang C Chen L Jiang Y et al.

Quelle: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2470310. Date of Electronic Publication: 2025 Feb 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/genetics , ATP Binding Cassette Transporter 1*/metabolism , Foam Cells*/drug effects , Foam Cells*/metabolism , Foam Cells*/cytology , Up-Regulation*/drug effects , Quinazolinones*/pharmacology , Quinazolinones*/chemical synthesis , Quinazolinones*/chemistry, Humans ; Structure-Activity Relationship ; Mice ; Animals ; Molecular Structure ; Dose-Response Relationship, Drug ; RAW 264.7 Cells ; Hep G2 Cells ; Macrophages/drug effects ; Macrophages/metabolism

Research Status and Latest Progress in the Regulatory Mechanisms of ABCA1.

Autoren: Chen X Zhou Y Yang J et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 08; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 08.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Cholesterol*/metabolism, Humans ; Animals ; Homeostasis ; Protein Processing, Post-Translational ; Biological Transport ; Gene Expression Regulation

Potential Effects of Nicotinamide on Serum HDL-Cholesterol Levels and Hepatic Oxidative Stress, ABCA1 Gene and Protein Expression in Rats Fed a High-Fat/Fructose Diet.

Autoren: Serafín-Fabián JI Ramírez-Cruz A Villeda-González JD et al.

Quelle: Nutrients [Nutrients] 2025 Nov 01; Vol. 17 (21). Date of Electronic Publication: 2025 Nov 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE

MeSH-Schlagworte: Oxidative Stress*/drug effects , ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Diet, High-Fat*/adverse effects , Cholesterol, HDL*/blood , Liver*/metabolism , Liver*/drug effects , Fructose*/adverse effects , Fructose*/administration & dosage , Niacinamide*/pharmacology, Animals ; Male ; Rats, Sprague-Dawley ; Rats ; Antioxidants/pharmacology ; Gene Expression/drug effects ; Lipid Metabolism/drug effects

LPCAT3-ABCA1 axis regulates the dose-sparing effects of steroid drugs in osteoarthritis in mice.

Autoren: Kondreddy V Magisetty J Kathirvel M et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Nov; Vol. 330 (Pt 3), pp. 148140. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Osteoarthritis*/drug therapy , Osteoarthritis*/metabolism , Osteoarthritis*/pathology , Osteoarthritis*/genetics , 1-Acylglycerophosphocholine O-Acyltransferase*/metabolism , 1-Acylglycerophosphocholine O-Acyltransferase*/genetics , Methylprednisolone*/pharmacology, Animals ; Mice ; Chondrocytes/metabolism ; Chondrocytes/drug effects ; Male ; Liver X Receptors/metabolism ; Disease Models, Animal ; Humans ; Benzenesulfonamides ; Fluorocarbons

Wild Cordyceps Polysaccharides Alleviate Atherosclerosis by Attenuating Macrophage Cholesterol Accumulation Through the PPARγ-LXRα-ABCA1/ABCG1 Pathway.

Autoren: Liu S Yang C Zhou X et al.

Quelle: Journal of medicinal food [J Med Food] 2025 Nov; Vol. 28 (11), pp. 1110-1123. Date of Electronic Publication: 2025 Sep 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9812512 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7600 (Electronic) Linking ISSN: 1096620X NLM ISO Abbreviation: J Med Food Subsets: MEDLINE

MeSH-Schlagworte: Atherosclerosis*/metabolism , Atherosclerosis*/drug therapy , Atherosclerosis*/genetics , PPAR gamma*/metabolism , PPAR gamma*/genetics , ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Macrophages*/metabolism , Macrophages*/drug effects , Cordyceps*/chemistry , Cholesterol*/metabolism , Liver X Receptors*/metabolism , Liver X Receptors*/genetics , ATP Binding Cassette Transporter, Subfamily G, Member 1*/metabolism , ATP Binding Cassette Transporter, Subfamily G, Member 1*/genetics , Polysaccharides*/administration & dosage , Polysaccharides*/chemistry , Fungal Polysaccharides*/administration & dosage , Fungal Polysaccharides*/chemistry, Animals ; Mice ; RAW 264.7 Cells ; Male ; Mice, Inbred C57BL ; Humans ; Signal Transduction/drug effects ; Diet, High-Fat/adverse effects

Shear Stress Regulates ABCA1-Dependent Membrane Cholesterol Content in Endothelial Cells Facilitating H 2 S-Dependent Vasodilation.

Autoren: Anderson JR Kanagy NL Gonzalez Bosc LV et al.

Quelle: Microcirculation (New York, N.Y. : 1994) [Microcirculation] 2025 Oct; Vol. 32 (7), pp. e70029.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9434935 Publication Model: Print Cited Medium: Internet ISSN: 1549-8719 (Electronic) Linking ISSN: 10739688 NLM ISO Abbreviation: Microcirculation Subsets: MEDLINE

MeSH-Schlagworte: Vasodilation*/drug effects , Vasodilation*/physiology , Cholesterol*/metabolism , ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/biosynthesis , Endothelial Cells*/metabolism , Stress, Mechanical* , Hydrogen Sulfide*/pharmacology , Hydrogen Sulfide*/metabolism , Cell Membrane*/metabolism, Animals ; Male ; Humans ; Rats ; Rats, Sprague-Dawley ; Mesenteric Arteries/metabolism ; Cells, Cultured

Ertugliflozin attenuates atherosclerosis in nondiabetic ApoE ^-/- mice by upregulating ABCA1 and LDLR via the PPARγ/LXRα pathway.

Autoren: Yang J Zhang B Zhao F et al.

Quelle: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Oct; Vol. 1871 (7), pp. 167927. Date of Electronic Publication: 2025 May 24.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE

MeSH-Schlagworte: Atherosclerosis*/drug therapy , Atherosclerosis*/metabolism , Atherosclerosis*/pathology , Atherosclerosis*/genetics , PPAR gamma*/metabolism , PPAR gamma*/genetics , Receptors, LDL*/metabolism , Receptors, LDL*/genetics , Apolipoproteins E*/genetics , Apolipoproteins E*/deficiency , Liver X Receptors*/metabolism , Liver X Receptors*/genetics , Bridged Bicyclo Compounds, Heterocyclic*/pharmacology , ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics, Animals ; Mice ; Male ; Signal Transduction/drug effects ; Up-Regulation/drug effects ; Plaque, Atherosclerotic/pathology ; Plaque, Atherosclerotic/drug therapy ; Plaque, Atherosclerotic/metabolism ; Mice, Knockout, ApoE ; Diet, High-Fat/adverse effects ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Mice, Knockout ; Mice, Inbred C57BL

Echinacoside suppresses macrophage lipid accumulation and attenuates atherosclerosis via the MDM2/PPARγ/ABCA1 signaling axis.

Autoren: Zhou QY Zhou J Li ZB et al.

Quelle: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2025 Oct; Vol. 1870 (7), pp. 159681. Date of Electronic Publication: 2025 Aug 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE

MeSH-Schlagworte: Atherosclerosis*/metabolism , Atherosclerosis*/drug therapy , Atherosclerosis*/pathology , PPAR gamma*/metabolism , PPAR gamma*/genetics , ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Proto-Oncogene Proteins c-mdm2*/metabolism , Proto-Oncogene Proteins c-mdm2*/genetics , Lipid Metabolism*/drug effects , Macrophages*/metabolism , Macrophages*/drug effects , Glycosides*/pharmacology, Animals ; Mice ; Signal Transduction/drug effects ; Mice, Inbred C57BL ; Male ; Foam Cells/metabolism ; Foam Cells/drug effects ; Diet, High-Fat/adverse effects ; Cholesterol/metabolism

ABCA1 modifies plasma membrane organization of living cells.

Autoren: Kondratowicz M Wu A Grela E et al.

Quelle: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2025 Oct; Vol. 1870 (7), pp. 159667. Date of Electronic Publication: 2025 Jul 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Cell Membrane*/metabolism, Humans ; Membrane Microdomains/metabolism ; Membrane Fluidity ; Membrane Lipids/metabolism ; Cholesterol/metabolism

ABC Transporters, APOE, CYP46A1, and LRP1 Gene Polymorphisms as Markers of Dementia Development in Patients with Hyperlipidemia.

Autoren: Machowska M Leszek J Rączy-Krzemianowska M et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 05; Vol. 26 (21). Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Hyperlipidemias*/genetics , Hyperlipidemias*/complications , Apolipoproteins E*/genetics , Dementia*/genetics , Dementia*/etiology , Polymorphism, Single Nucleotide* , ATP Binding Cassette Transporter 1*/genetics , Low Density Lipoprotein Receptor-Related Protein-1*/genetics , ATP-Binding Cassette Transporters*/genetics, Humans ; Male ; Female ; Aged ; Genetic Predisposition to Disease ; Genotype ; Middle Aged ; Alleles ; Gene Frequency ; Biomarkers ; Alzheimer Disease/genetics ; Aged, 80 and over ; Case-Control Studies

DNA N6-methyladenine and ABCA1 methylation associations with subclinical coronary atherosclerosis in people with HIV.

Autoren: Bernardino JI Dalmau R Rodriguez-Torres D et al.

Quelle: Clinical epigenetics [Clin Epigenetics] 2025 Oct 03; Vol. 17 (1), pp. 158. Date of Electronic Publication: 2025 Oct 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083 (Electronic) Linking ISSN: 18687075 NLM ISO Abbreviation: Clin Epigenetics Subsets: MEDLINE

MeSH-Schlagworte: DNA Methylation* , Coronary Artery Disease*/genetics , Coronary Artery Disease*/complications , ATP Binding Cassette Transporter 1*/genetics , HIV Infections*/complications , HIV Infections*/genetics , Adenine*/analogs & derivatives, Humans ; Male ; Female ; Middle Aged ; Cross-Sectional Studies ; Adult ; Plaque, Atherosclerotic/genetics ; Promoter Regions, Genetic ; Epigenesis, Genetic

Melatonin ameliorates ox-LDL-induced lipid accumulation and enhances ABCA1 expression in VSMCs via inhibition of the TRPV1-Ca ²⁺ -calpain signaling pathway.

Autoren: Tang Y Peng Y Zhang Y et al.

Quelle: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2026 Jan; Vol. 1871 (1), pp. 159704. Date of Electronic Publication: 2025 Nov 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , TRPV Cation Channels*/metabolism , Lipoproteins, LDL*/metabolism , Calpain*/metabolism , Muscle, Smooth, Vascular*/metabolism , Muscle, Smooth, Vascular*/drug effects , Muscle, Smooth, Vascular*/cytology , Myocytes, Smooth Muscle*/metabolism , Myocytes, Smooth Muscle*/drug effects , Lipid Metabolism*/drug effects, Animals ; Mice ; Calcium/metabolism ; Signal Transduction/drug effects ; Male ; Atherosclerosis/metabolism ; Atherosclerosis/drug therapy ; Atherosclerosis/pathology ; Mice, Inbred C57BL ; Diet, High-Fat/adverse effects

Euphorbia diterpenoids from Euphorbia peplus possessing anti-Alzheimer's activity via targeting PPARγ and upregulating the level of ABCA1.

Autoren: Yang Y He S Lin Y et al.

Quelle: Phytochemistry [Phytochemistry] 2026 Feb; Vol. 242, pp. 114712. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE

MeSH-Schlagworte: Euphorbia*/chemistry , PPAR gamma*/metabolism , PPAR gamma*/antagonists & inhibitors , ATP Binding Cassette Transporter 1*/metabolism , Diterpenes*/pharmacology , Diterpenes*/chemistry , Diterpenes*/isolation & purification , Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism, Up-Regulation/drug effects ; Molecular Structure ; Molecular Docking Simulation ; Animals ; Mice ; Humans ; Dose-Response Relationship, Drug ; Structure-Activity Relationship

SCR Organism: Euphorbia peplus

Direct Visualization of ATP-Binding Cassette Protein A1 Mediated Nascent High-Density Lipoprotein Biogenesis by High-Speed Atomic Force Microscopy.

Autoren: Kodan A Amyot R Umeda K et al.

Quelle: Nano letters [Nano Lett] 2025 Sep 10; Vol. 25 (36), pp. 13563-13570. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101088070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6992 (Electronic) Linking ISSN: 15306984 NLM ISO Abbreviation: Nano Lett Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/chemistry , Microscopy, Atomic Force*/methods , Lipoproteins, HDL*/biosynthesis , Lipoproteins, HDL*/chemistry , Lipoproteins, HDL*/metabolism, Humans ; Apolipoprotein A-I/metabolism ; Apolipoprotein A-I/chemistry ; Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/chemistry

Itaconate alleviates cholesterol burden via ABCA1 stabilization and cholesterol efflux.

Autoren: Hong NE Ravodina AM Asase C et al.

Quelle: Atherosclerosis [Atherosclerosis] 2025 Sep; Vol. 408, pp. 120445. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0242543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1484 (Electronic) Linking ISSN: 00219150 NLM ISO Abbreviation: Atherosclerosis Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Cholesterol*/metabolism , Atherosclerosis*/metabolism , Atherosclerosis*/pathology , Atherosclerosis*/genetics , Atherosclerosis*/drug therapy , Succinates*/pharmacology , Succinates*/pharmacokinetics , Aortic Diseases*/pathology , Aortic Diseases*/genetics , Aortic Diseases*/metabolism , Aortic Diseases*/prevention & control, Animals ; Mice ; Plaque, Atherosclerotic ; RAW 264.7 Cells ; Foam Cells/metabolism ; Foam Cells/drug effects ; Male ; Disease Models, Animal ; Lipid Metabolism/drug effects ; Mice, Inbred C57BL ; Macrophages/metabolism ; Macrophages/drug effects ; Mice, Knockout, ApoE ; Triglycerides/metabolism ; Diet, High-Fat

UBE3A promotes foam cell formation and counters remyelination by targeting ABCA1 for proteasomal degradation.

Autoren: Loix M Vanherle S Bolkaerts L et al.

Quelle: Nature communications [Nat Commun] 2025 Aug 29; Vol. 16 (1), pp. 8077. Date of Electronic Publication: 2025 Aug 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Remyelination*/physiology , Proteasome Endopeptidase Complex*/metabolism , Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Foam Cells*/metabolism, Animals ; Mice ; Ubiquitination ; Humans ; Proteolysis ; Mice, Inbred C57BL ; Myelin Sheath/metabolism ; Mice, Knockout ; Brain/metabolism ; Male

IGF2BP1-mediated methylation of ABCA1 facilitates tumor progression by affecting cholesterol metabolism in lung adenocarcinoma.

Autoren: Xu S Liu K Chen Z et al.

Quelle: Amino acids [Amino Acids] 2025 Aug 22; Vol. 57 (1), pp. 42. Date of Electronic Publication: 2025 Aug 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9200312 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-2199 (Electronic) Linking ISSN: 09394451 NLM ISO Abbreviation: Amino Acids Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/genetics , Cholesterol*/metabolism , Lung Neoplasms*/metabolism , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Adenocarcinoma of Lung*/metabolism , Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics, Humans ; Animals ; Mice ; Gene Expression Regulation, Neoplastic ; Disease Progression ; Methylation ; Cell Proliferation ; Cell Line, Tumor ; Mice, Nude

Functional characterization of genetic variants affecting the intracellular domains of ATP-binding cassette transporter A1 (ABCA1).

Autoren: Teigen M Ølnes ÅS Bjune K et al.

Quelle: Journal of lipid research [J Lipid Res] 2025 Aug; Vol. 66 (8), pp. 100854. Date of Electronic Publication: 2025 Jul 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE

MeSH-Schlagworte: ATP Binding Cassette Transporter 1*/genetics , ATP Binding Cassette Transporter 1*/metabolism , ATP Binding Cassette Transporter 1*/chemistry , Genetic Variation*, Humans ; Protein Domains ; Cholesterol/metabolism ; HEK293 Cells

HBV-miR-3 induces hepatic cholesterol accumulation by targeting ABCA1: Evidence for potential benefits of statin usage.

Autoren: Chowdhari S Deep A Ahmad B et al.

Quelle: Journal of lipid research [J Lipid Res] 2025 Aug; Vol. 66 (8), pp. 100866. Date of Electronic Publication: 2025 Jul 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE

MeSH-Schlagworte: MicroRNAs*/genetics , MicroRNAs*/metabolism , ATP Binding Cassette Transporter 1*/genetics , ATP Binding Cassette Transporter 1*/metabolism , Hepatitis B virus*/genetics , Cholesterol*/metabolism , Liver*/metabolism , Liver*/drug effects , Liver*/virology , Liver*/pathology , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology, Humans ; Hepatocytes/metabolism ; Hepatocytes/drug effects ; Male ; Female ; Hep G2 Cells ; Lipid Metabolism