Výsledky vyhľadávania - "ARHGAP18"

Upregulation of ARHGAP18 by miR-613 Inhibits Cigarette Smoke Extract-Induced Apoptosis and Epithelial-Mesenchymal Transition in Bronchial Epithelial Cells

Autori: Fu H Liu K Zheng Y a ďalší

Zdroj: Int J Chron Obstruct Pulmon Dis
International Journal of COPD, Vol Volume 20, Iss Issue 1, Pp 2525-2537 (2025)

Predmety: Diseases of the respiratory system, RC705-779, Chronic obstructive pulmonary disease, miR-613, apoptosis, epithelial-mesenchymal transition, ARHGAP18, Original Research

Prístupová URL adresa: https://doaj.org/article/99894dd286f34e05aeb8f0284a7a4c20

YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment

Autori: Paul R. Coleman Angelina J. Lay Ka Ka Ting a ďalší

Zdroj: Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-12 (2020)

Predmety: ARHGAP18, Endothelial cells, YAP, Mechanotransduction, Inflammation, Medicine, Cytology, QH573-671

Popis súboru: electronic resource

Relation: https://doaj.org/toc/1478-811X

Prístupová URL adresa: https://doaj.org/article/b16eece7e7754260b2573b55236c9117

LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage

Autori: Sherwin S. Yen Maya Styner Keith Burridge a ďalší

Prispievatelia: Sherwin S. Yen Maya Styner Keith Burridge a ďalší

Zdroj: Bone. 107:172-180

Predmety: Male, rho GTP-Binding Proteins, 0301 basic medicine, LARG, Bone Marrow Cells, ARHGAP18, adipogenesis, osteogenesis, Mice, 03 medical and health sciences, Osteogenesis, Animals, Cell Lineage, Biomedical Engineering and Bioengineering, mesenchymal stem cells, 0303 health sciences, Adipogenesis, Mechanical Engineering, GTPase-Activating Proteins, RhoA, Cell Differentiation, Mesenchymal Stem Cells, Adaptation, Physiological, BRC, Mice, Inbred C57BL, Stress, Mechanical, rhoA GTP-Binding Protein, Rho Guanine Nucleotide Exchange Factors

Popis súboru: application/pdf

Prístupová URL adresa: https://europepmc.org/articles/pmc5743610?pdf=render
https://pubmed.ncbi.nlm.nih.gov/29208526
https://www.sciencedirect.com/science/article/pii/S8756328217304416
http://www.ncbi.nlm.nih.gov/pubmed/29208526
https://core.ac.uk/display/146989135
https://scholarworks.boisestate.edu/mecheng_facpubs/87/
https://works.bepress.com/gunes-uzer/11/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743610/

Rho-GTPase activating-protein 18: a biomarker associated with good prognosis in invasive breast cancer

Autori: Aleskandarany, Mohammed A Sonbul, Sultan Surridge, Rachel a ďalší

Prispievatelia: Aleskandarany, Mohammed A Sonbul, Sultan Surridge, Rachel a ďalší

Zdroj: Br J Cancer

Predmety: Nottingham Breast Cancer Research Centre, Epithelial-Mesenchymal Transition, Carcinoma, Ductal, Breast, GTPase-Activating Proteins, A100, Breast Neoplasms, Middle Aged, ARHGAP18, Lymphovascular invasion, Immunohistochemistry, Breast cancer, Prognosis, Prognosis, Immunohistochemistry, Tumor Burden, 3. Good health, Carcinoma, Lobular, 03 medical and health sciences, 0302 clinical medicine, Humans, Female, Neoplasm Invasiveness, RNA, Messenger, Molecular Diagnostics, Neoplasm Staging, Proportional Hazards Models

Popis súboru: application/pdf; PDF

Prístupová URL adresa: https://www.nature.com/articles/bjc2017261.pdf
https://pubmed.ncbi.nlm.nih.gov/28829761
https://europepmc.org/article/PMC/PMC5674094
https://www.nature.com/articles/bjc2017261
http://eprints.nottingham.ac.uk/44298/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674094/
https://www.nature.com/articles/bjc2017261.pdf
https://pubmed.ncbi.nlm.nih.gov/28829761/
https://www.repository.cam.ac.uk/handle/1810/292101
https://doi.org/10.1038/bjc.2017.261
https://doi.org/10.17863/cam.39256

A Screen for PKN3 Substrates Reveals an Activating Phosphorylation of ARHGAP18

Autori: Michal Dibus Jan Brábek Daniel Rösel

Zdroj: International Journal of Molecular Sciences, Vol 21, Iss 7769, p 7769 (2020)

Predmety: PKN3, phosphorylation, phosphoproteomic screen, ARHGAP18, Rho-GTP, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/21/20/7769; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/6cd6463a29cc4f42ba5e18286e378e64

Dostupnosť: https://doi.org/10.3390/ijms21207769
https://doaj.org/article/6cd6463a29cc4f42ba5e18286e378e64

ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis

Autori: Angelina J. Lay Paul R. Coleman Ann Formaz‐Preston a ďalší

Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 2 (2019)

Predmety: animal model, ARHGAP18, endothelial cell, atherosclerosis, Diseases of the circulatory (Cardiovascular) system, RC666-701

Popis súboru: electronic resource

Relation: https://doaj.org/toc/2047-9980

Prístupová URL adresa: https://doaj.org/article/4246dd9cdf2b4f87b31453c111a86454

Over-expression of ARHGAP18 suppressed cell proliferation, migration, invasion, and tumor growth in gastric cancer by restraining over-activation of MAPK signaling pathways

Autori: Li Y Ji S Fu L a ďalší

Zdroj: OncoTargets and Therapy, Vol Volume 11, Pp 279-290 (2018)

Predmety: ARHGAP18, gastric cancer, cell proliferation, migration, invasion, MAPK, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.dovepress.com/over-expression-of-arhgap18--suppressed-cell-proliferation-migration-i-peer-reviewed-article-OTT; https://doaj.org/toc/1178-6930; https://doaj.org/article/9112a125bfb44033b5fc4deed0e84caf

Dostupnosť: https://doaj.org/article/9112a125bfb44033b5fc4deed0e84caf

Human brain arteriovenous malformation: an analysis of differential expressed genes

Autori: Liu, Xing Meng, Guolu Yu, Tengfei a ďalší

Predmety: Brain arteriovenous malformations, Gene microarray technique, VCAN, SPARK, ARHGAP18, MAPK pathway

Relation: http://www.cnjournal.org/content/2/1/43

Dostupnosť: http://www.cnjournal.org/content/2/1/43

LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage

Autori: Thompson, William R. Yen, Sherwin S. Uzer, Gunes a ďalší

Prispievatelia: Thompson, William R. Yen, Sherwin S. Uzer, Gunes a ďalší

Zdroj: Author

Predmety: LARG, ARHGAP18, RhoA

Popis súboru: application/pdf

Relation: Bone; https://hdl.handle.net/1805/15001

Dostupnosť: https://hdl.handle.net/1805/15001

LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage

Autori: Thompson, William R. Yen, Sherwin S. Uzer, Gunes a ďalší

Zdroj: Bone, 107

Predmety: enhancement, cytoskeletal structures, GEF, bone, alkaline, physical factors, fate, adipogenic markers, quality, activation of RhoA, static state, quality of bone, work, fiber formation, RhoA, cell lineages, culture, mesenchymal stem cell lineages, BGLAP gene, qPCR, stress fiber formation, mechanical activation, response, lineage decisions, microenvironment, inhibit adipogenesis, commitment, Oil Red O, ARHGAP18, static culture

Relation: https://cdr.lib.unc.edu/downloads/6t053w32q?file=thumbnail; https://cdr.lib.unc.edu/downloads/6t053w32q

Dostupnosť: https://doi.org/10.17615/sg2p-4h46
https://cdr.lib.unc.edu/downloads/6t053w32q?file=thumbnail
https://cdr.lib.unc.edu/downloads/6t053w32q

ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions

Autori: Chang, Garry H. K. Lay, Angelina J. Ting, Ka Ka a ďalší

Zdroj: Small GTPases. 5:e975002

Predmety: rho GTP-Binding Proteins, 0301 basic medicine, 1303 Biochemistry, Melanoma, Experimental, Neovascularization, Physiologic, Retina, 1307 Cell Biology, Cell junctions, Mice, 03 medical and health sciences, Cell Line, Tumor, Human Umbilical Vein Endothelial Cells, Animals, Humans, Arhgap18, Zebrafish, 0303 health sciences, GTPase-Activating Proteins, Endothelial Cells, Senex, Zebrafish Proteins, 3. Good health, Mice, Inbred C57BL, Intercellular Junctions, 13. Climate action, Angiogenesis, Sprouting

Prístupová URL adresa: https://www.tandfonline.com/doi/pdf/10.4161/21541248.2014.975002?needAccess=true
https://pubmed.ncbi.nlm.nih.gov/25425145
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601187/
https://europepmc.org/abstract/MED/25425145
https://core.ac.uk/display/43362365
https://www.tandfonline.com/doi/full/10.4161/21541248.2014.975002
https://www.tandfonline.com/doi/pdf/10.4161/21541248.2014.975002
https://espace.library.uq.edu.au/view/UQ:349170

ARHGAP18 is Upregulated by Transcription Factor GATA1 Promotes the Proliferation and Invasion in Hepatocellular Carcinoma.

Autori: Chen P Liu X Liu Y a ďalší

Zdroj: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2024 Feb; Vol. 196 (2), pp. 679-689. Date of Electronic Publication: 2023 May 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 8208561 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0291 (Electronic) Linking ISSN: 02732289 NLM ISO Abbreviation: Appl Biochem Biotechnol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Carcinoma, Hepatocellular*/pathology , Liver Neoplasms*/pathology, Humans ; GATA1 Transcription Factor/genetics ; GATA1 Transcription Factor/metabolism ; Gene Expression Regulation ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Cell Movement/genetics ; GTPase-Activating Proteins/genetics ; GTPase-Activating Proteins/metabolism

Liquiritigenin alleviates doxorubicin-induced chronic heart failure via promoting ARHGAP18 and suppressing RhoA/ROCK1 pathway.

Autori: Xu Z Hu Z Xu H a ďalší

Zdroj: Experimental cell research [Exp Cell Res] 2022 Feb 15; Vol. 411 (2), pp. 113008. Date of Electronic Publication: 2022 Jan 04.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2422 (Electronic) Linking ISSN: 00144827 NLM ISO Abbreviation: Exp Cell Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Flavanones/*pharmacology , GTPase-Activating Proteins/*metabolism , Heart Failure/*drug therapy , rho GTP-Binding Proteins/*antagonists & inhibitors , rho-Associated Kinases/*antagonists & inhibitors, Animals ; Apoptosis/drug effects ; Cell Line ; Chronic Disease ; Disease Models, Animal ; Down-Regulation ; Doxorubicin/toxicity ; GTPase-Activating Proteins/antagonists & inhibitors ; GTPase-Activating Proteins/genetics ; Gene Knockdown Techniques ; Glycyrrhiza/chemistry ; Heart Failure/chemically induced ; Heart Failure/metabolism ; Medicine, Chinese Traditional ; Plants, Medicinal ; Rats ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; rho GTP-Binding Proteins/metabolism ; rho-Associated Kinases/metabolism

Advanced glycosylation end products (AGEs) controls proliferation, invasion and permeability through orchestrating ARHGAP18/RhoA pathway in human umbilical vein endothelial cells.

Autori: Li X Tao Y Wang X a ďalší

Zdroj: Glycoconjugate journal [Glycoconj J] 2020 Apr; Vol. 37 (2), pp. 209-219. Date of Electronic Publication: 2020 Feb 03.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Springer Country of Publication: United States NLM ID: 8603310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4986 (Electronic) Linking ISSN: 02820080 NLM ISO Abbreviation: Glycoconj J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cell Movement* , Cell Proliferation*, GTPase-Activating Proteins/*metabolism , Glycation End Products, Advanced/*metabolism , Human Umbilical Vein Endothelial Cells/*metabolism , rhoA GTP-Binding Protein/*metabolism, Cells, Cultured ; GTPase-Activating Proteins/genetics ; Human Umbilical Vein Endothelial Cells/physiology ; Humans ; Signal Transduction ; rhoA GTP-Binding Protein/genetics

LncRNA CDKN2BAS predicts poor prognosis in patients with hepatocellular carcinoma and promotes metastasis via the miR-153-5p/ARHGAP18 signaling axis.

Autori: Chen J Huang X Wang W a ďalší

Zdroj: Aging [Aging (Albany NY)] 2018 Nov 29; Vol. 10 (11), pp. 3371-3381.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print Cited Medium: Internet ISSN: 1945-4589 (Electronic) Linking ISSN: 19454589 NLM ISO Abbreviation: Aging (Albany NY) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Carcinoma, Hepatocellular/*metabolism , GTPase-Activating Proteins/*metabolism , Liver Neoplasms/*metabolism , MicroRNAs/*metabolism , RNA, Long Noncoding/*metabolism, GTPase-Activating Proteins/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Metastasis ; RNA, Long Noncoding/genetics ; Signal Transduction/physiology

ARHGAP18 is a novel gene under positive natural selection that influences HbF levels in β-thalassaemia.

Autori: He Y Luo J Chen Y a ďalší

Zdroj: Molecular genetics and genomics : MGG [Mol Genet Genomics] 2018 Feb; Vol. 293 (1), pp. 207-216. Date of Electronic Publication: 2017 Oct 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101093320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1617-4623 (Electronic) Linking ISSN: 16174623 NLM ISO Abbreviation: Mol Genet Genomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fetal Hemoglobin/*genetics , GTPase-Activating Proteins/*genetics , Selection, Genetic/*genetics , beta-Thalassemia/*genetics, Adolescent ; Adult ; Apoptosis/genetics ; Cell Proliferation/genetics ; Child ; Child, Preschool ; Female ; Gene Expression Regulation/genetics ; Gene Knockout Techniques ; Genetic Association Studies ; Humans ; K562 Cells ; Lentivirus/genetics ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Young Adult ; beta-Thalassemia/blood ; beta-Thalassemia/pathology

Activation of human gonadotropin-releasing hormone receptor promotes down regulation of ARHGAP18 and regulates the cell invasion of MDA-MB-231 cells.

Autori: Aguilar-Rojas A Maya-Núñez G Huerta-Reyes M a ďalší

Zdroj: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2018 Jan 15; Vol. 460, pp. 94-103. Date of Electronic Publication: 2017 Jul 11.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: North Holland Publishing Country of Publication: Ireland NLM ID: 7500844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8057 (Electronic) Linking ISSN: 03037207 NLM ISO Abbreviation: Mol Cell Endocrinol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Down-Regulation/*genetics , GTPase-Activating Proteins/*genetics , Receptors, LHRH/*metabolism, Cell Adhesion ; Cell Line, Tumor ; Cell Proliferation ; Collagen Type I/metabolism ; GTPase-Activating Proteins/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Invasiveness ; Reproducibility of Results ; Wound Healing

Caveolae control the anti-inflammatory phenotype of senescent endothelial cells.

Autori: Powter EE Coleman PR Tran MH a ďalší

Zdroj: Aging cell [Aging Cell] 2015 Feb; Vol. 14 (1), pp. 102-11. Date of Electronic Publication: 2014 Nov 19.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cellular Senescence*, Anti-Inflammatory Agents/*metabolism , Caveolae/*metabolism , Human Umbilical Vein Endothelial Cells/*cytology , Human Umbilical Vein Endothelial Cells/*metabolism , Inflammation/*pathology, Animals ; Carrier Proteins/metabolism ; Caveolin 1/metabolism ; GTPase-Activating Proteins/metabolism ; Gene Knockdown Techniques ; Humans ; Mice ; NF-kappa B/metabolism ; Phenotype ; Phosphate-Binding Proteins ; RNA-Binding Proteins/metabolism ; Transcription Factor AP-1/metabolism ; Up-Regulation

Rho-GTPase activating protein 18: a biomarker associated with good prognosis in invasive breast cancer

Autori: Aleskandarany, Mohammed A. Sonbul, Sultan N. Surridge, Rachel a ďalší

Témy: ARHGAP18, Lymphovascular invasion, Immunohistochemistry, Breast cancer, Prognosis, Article, PeerReviewed

URL: https://eprints.nottingham.ac.uk/44298/
http://www.nature.com/bjc/journal/vaop/ncurrent/full/bjc2017261a.html?foxtrotcallback=true
https://eprints.nottingham.ac.uk/44298
http://www.nature.com/bjc/journal/vaop/ncurrent/full/bjc2017261a.html?foxtrotcallback=true
doi:10.1038/bjc.2017.261