Suchergebnisse - "AMIDES"

Inhibition of cytochrome bd oxidase in Mycobacterium tuberculosis by benzothiazole amides.

Autoren: Kumar R Roy A Kalia NP et al.

Quelle: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2025 Nov 01; Vol. 129, pp. 118323. Date of Electronic Publication: 2025 Jul 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Benzothiazoles*/chemistry , Benzothiazoles*/pharmacology , Benzothiazoles*/chemical synthesis , Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/enzymology , Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Antitubercular Agents*/chemical synthesis , Amides*/chemistry , Amides*/pharmacology , Amides*/chemical synthesis , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/chemical synthesis, Molecular Docking Simulation ; Microbial Sensitivity Tests ; Structure-Activity Relationship ; Humans ; Molecular Structure ; Dose-Response Relationship, Drug

Discovery of a heterocyclic aromatic amide based P-gp inhibitor as coadjutant regulating autophagy against drug resistance in breast cancer.

Autoren: Xue WH Zhang X Guo S et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118151. Date of Electronic Publication: 2025 Sep 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Autophagy*/drug effects , Drug Resistance, Neoplasm*/drug effects , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Amides*/pharmacology , Amides*/chemistry , Amides*/chemical synthesis , ATP Binding Cassette Transporter, Subfamily B, Member 1*/antagonists & inhibitors , ATP Binding Cassette Transporter, Subfamily B, Member 1*/metabolism , Drug Discovery* , Heterocyclic Compounds*/pharmacology , Heterocyclic Compounds*/chemistry , Heterocyclic Compounds*/chemical synthesis, Humans ; Female ; Structure-Activity Relationship ; Animals ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Molecular Structure ; Mice ; Dose-Response Relationship, Drug ; Apoptosis/drug effects ; Mice, Inbred BALB C ; Cell Line, Tumor

Potential role of Aliskiren in cancer modulation compared to other Renin-Angiotensin inhibitors: an in-depth review.

Autoren: De A Calcutta A Della Pietra GP et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Dec 05; Vol. 1008, pp. 178312. Date of Electronic Publication: 2025 Oct 31.

Publikationsart: Journal Article; Systematic Review; Review; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Fumarates*/therapeutic use , Fumarates*/pharmacology , Amides*/therapeutic use , Amides*/pharmacology , Neoplasms*/drug therapy , Neoplasms*/pathology , Neoplasms*/metabolism , Renin-Angiotensin System*/drug effects , Angiotensin-Converting Enzyme Inhibitors*/therapeutic use , Angiotensin-Converting Enzyme Inhibitors*/pharmacology , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/pharmacology, Humans ; Animals ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin Receptor Antagonists/pharmacology ; Renin/antagonists & inhibitors

Discovery and optimization of OA amide derivatives containing a trisubstituted l-hydroxyproline fragment as novel Omicron fusion inhibitors.

Autoren: Hong C Su H Lu L et al.

Quelle: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118058. Date of Electronic Publication: 2025 Aug 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Amides*/chemistry , Amides*/pharmacology , Amides*/chemical synthesis , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Antiviral Agents*/chemical synthesis , Betacoronavirus*/drug effects , Drug Discovery* , Hydroxyproline*/chemistry , Hydroxyproline*/pharmacology , SARS-CoV-2*/drug effects , Virus Internalization*/drug effects, Animals ; Humans ; Chlorocebus aethiops ; Dose-Response Relationship, Drug ; Molecular Docking Simulation ; Structure-Activity Relationship ; Saponins/chemical synthesis ; Saponins/chemistry ; Saponins/pharmacology

Comprehensive Overview of Pyrazole Amide Derivatives as Novel Pesticides for Crop Protection and Pest Management.

Autoren: Luo B Hu Y Wu Y et al.

Quelle: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Dec 03; Vol. 73 (48), pp. 30582-30600. Date of Electronic Publication: 2025 Nov 21.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

MeSH-Schlagworte: Pyrazoles*/chemistry , Pyrazoles*/pharmacology , Amides*/chemistry , Amides*/pharmacology , Pesticides*/chemistry , Pesticides*/pharmacology, Animals ; Pest Control ; Crop Protection ; Structure-Activity Relationship ; Crops, Agricultural/drug effects ; Crops, Agricultural/growth & development ; Insecticides/chemistry ; Insecticides/pharmacology

Design and semisynthesis of novel oleanolic acid-based tertiary amide derivatives as promising antifungal agents against phytopathogenic fungi.

Autoren: Sui G Sun J Zhang A et al.

Quelle: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6097-6105. Date of Electronic Publication: 2025 Feb 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

MeSH-Schlagworte: Antifungal Agents*/pharmacology , Antifungal Agents*/chemical synthesis , Antifungal Agents*/chemistry , Amides*/chemistry , Amides*/pharmacology , Amides*/chemical synthesis , Oleanolic Acid*/chemistry , Oleanolic Acid*/pharmacology , Oleanolic Acid*/chemical synthesis , Drug Design*, Structure-Activity Relationship ; Microbial Sensitivity Tests ; Mycelium/drug effects ; Botrytis/drug effects

ESCALÓN: A Prospective Randomized Trial of Corneal Endothelial Cell Therapy in Subjects With Corneal Edema.

Autoren: Holland EJ Yeu E Giegengack M et al.

Quelle: Cornea [Cornea] 2025 Dec 01; Vol. 44 (12), pp. 1497-1507. Date of Electronic Publication: 2025 Mar 03.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8216186 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-4798 (Electronic) Linking ISSN: 02773740 NLM ISO Abbreviation: Cornea Subsets: MEDLINE

MeSH-Schlagworte: Corneal Edema*/therapy , Corneal Edema*/etiology , Corneal Edema*/physiopathology , Corneal Edema*/surgery , Endothelium, Corneal*/transplantation , Endothelium, Corneal*/cytology , Amides*/therapeutic use , Amides*/adverse effects , Amides*/administration & dosage , Pyridines*/therapeutic use , Pyridines*/adverse effects , Pyridines*/administration & dosage , Cell- and Tissue-Based Therapy*/methods, Humans ; Prospective Studies ; Male ; Double-Blind Method ; Female ; Middle Aged ; Visual Acuity/physiology ; Aged ; rho-Associated Kinases/antagonists & inhibitors ; Fuchs' Endothelial Dystrophy/complications ; Enzyme Inhibitors/therapeutic use ; Enzyme Inhibitors/administration & dosage ; Cells, Cultured ; Adult ; Corneal Pachymetry ; Aged, 80 and over ; Treatment Outcome

Four new piperidine amide alkaloids from Piper longum fruits and their anti-inflammatory activities.

Autoren: Li T Yu XY Chen XY et al.

Quelle: Fitoterapia [Fitoterapia] 2025 Dec; Vol. 187, pp. 106899. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

MeSH-Schlagworte: Alkaloids*/isolation & purification , Alkaloids*/pharmacology , Alkaloids*/chemistry , Piper*/chemistry , Anti-Inflammatory Agents*/isolation & purification , Anti-Inflammatory Agents*/pharmacology , Piperidines*/isolation & purification , Piperidines*/pharmacology , Piperidines*/chemistry , Amides*/isolation & purification , Amides*/pharmacology, Animals ; Mice ; Fruit/chemistry ; RAW 264.7 Cells ; Molecular Structure ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism ; China

Design, synthesis, antifungal, and antibacterial evaluation of ferulic acid derivatives bearing amide moiety.

Autoren: Fei Q Luo Y Chen H et al.

Quelle: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 5577-5591. Date of Electronic Publication: 2024 Dec 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

MeSH-Schlagworte: Coumaric Acids*/chemistry , Coumaric Acids*/pharmacology , Coumaric Acids*/chemical synthesis , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Anti-Bacterial Agents*/chemistry , Drug Design* , Antifungal Agents*/pharmacology , Antifungal Agents*/chemical synthesis , Antifungal Agents*/chemistry , Amides*/chemistry , Amides*/pharmacology, Microbial Sensitivity Tests ; Molecular Docking Simulation ; Xanthomonas axonopodis/drug effects ; Plant Diseases/microbiology ; Plant Diseases/prevention & control ; Structure-Activity Relationship

Design, synthesis, and antibacterial activity of novel amide derivatives containing a sulfone moiety.

Autoren: Zou Y Liu X Zhu Z et al.

Quelle: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6079-6096. Date of Electronic Publication: 2025 Feb 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

MeSH-Schlagworte: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Anti-Bacterial Agents*/chemistry , Drug Design* , Sulfones*/chemistry , Sulfones*/pharmacology , Amides*/chemistry , Amides*/pharmacology , Amides*/chemical synthesis, Xanthomonas/drug effects ; Molecular Docking Simulation ; Microbial Sensitivity Tests ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Biofilms/drug effects

SCR Organism: Xanthomonas oryzae

Molecular docking and SARs guiding the gradual development of thiazole-2-yl amide derivatives containing biphenyl groups as promising antifungal scaffolds.

Autoren: Cheng X Zhang C Wang F et al.

Quelle: Pest management science [Pest Manag Sci] 2025 Dec; Vol. 81 (12), pp. 8007-8022. Date of Electronic Publication: 2025 Aug 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published for SCI by Wiley Country of Publication: England NLM ID: 100898744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4998 (Electronic) Linking ISSN: 1526498X NLM ISO Abbreviation: Pest Manag Sci Subsets: MEDLINE

MeSH-Schlagworte: Fungicides, Industrial*/pharmacology , Fungicides, Industrial*/chemistry , Amides*/chemistry , Amides*/pharmacology , Thiazoles*/chemistry , Thiazoles*/pharmacology , Biphenyl Compounds*/chemistry , Biphenyl Compounds*/pharmacology , Antifungal Agents*/pharmacology , Antifungal Agents*/chemistry, Molecular Docking Simulation ; Structure-Activity Relationship ; Ascomycota/drug effects ; Botrytis/drug effects ; Fusarium/drug effects

SCR Organism: Botrytis cinerea; Sclerotinia sclerotiorum; Fusarium graminearum

Correlation of amide I and III components in the human dentine infrared spectrum.

Autoren: Anastasiadis K; Private Practice.

Quelle: Dental materials journal [Dent Mater J] 2025 Nov 28; Vol. 44 (6), pp. 672-680. Date of Electronic Publication: 2025 Nov 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Japanese Society for Dental Materials and Devices Country of Publication: Japan NLM ID: 8309299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1361 (Electronic) Linking ISSN: 02874547 NLM ISO Abbreviation: Dent Mater J Subsets: MEDLINE

MeSH-Schlagworte: Dentin*/chemistry , Amides*/chemistry , Amides*/analysis, Humans ; Spectroscopy, Fourier Transform Infrared ; Phosphoric Acids/chemistry ; Collagen/chemistry ; Dentin-Bonding Agents/chemistry

Structure-Based Design and Optimization of Bi-Aryl Amide Derivatives as Nur77 Ligands for Nur77-Bcl-2-Dependent Apoptotic Cancer Therapy.

Autoren: Zhao T Chen J Hong W et al.

Quelle: Journal of medicinal chemistry [J Med Chem] 2025 Nov 27; Vol. 68 (22), pp. 24168-24195. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Nuclear Receptor Subfamily 4, Group A, Member 1*/metabolism , Apoptosis*/drug effects , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/pharmacokinetics , Drug Design* , Proto-Oncogene Proteins c-bcl-2*/metabolism , Amides*/pharmacology , Amides*/chemistry , Amides*/therapeutic use , Amides*/chemical synthesis , Amides*/pharmacokinetics, Humans ; Animals ; Ligands ; Structure-Activity Relationship ; Mice ; Cell Line, Tumor ; Male

Deazapurine Amide-Bond Synthetases: a New Family of Amide-Bond-Forming Enzymes Driving the Diversity of Peptidyl Deazapurine Natural Products.

Autoren: Ji CH Kim CI Yun B et al.

Quelle: Journal of the American Chemical Society [J Am Chem Soc] 2025 Nov 12; Vol. 147 (45), pp. 41668-41677. Date of Electronic Publication: 2025 Nov 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH-Schlagworte: Biological Products*/chemistry , Biological Products*/metabolism , Amides*/chemistry , Amides*/metabolism , Ligases*/metabolism , Ligases*/chemistry , Peptides*/chemistry , Peptides*/metabolism, Multigene Family

Engineering an Imine Reductase for Enantioselective Synthesis of Atropisomeric Amides.

Autoren: Yao Z Meng R Zhou Z et al.

Quelle: Journal of the American Chemical Society [J Am Chem Soc] 2025 Nov 05; Vol. 147 (44), pp. 40616-40625. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH-Schlagworte: Amides*/chemistry , Amides*/chemical synthesis , Amides*/metabolism , Oxidoreductases*/metabolism , Oxidoreductases*/chemistry , Oxidoreductases*/genetics , Imines*/metabolism , Imines*/chemistry , Protein Engineering*, Stereoisomerism ; Models, Molecular ; Biocatalysis ; Crystallography, X-Ray

Thienopyrimidine amide analogs target MmpL3 in Mycobacterium tuberculosis .

Autoren: Baldin VP Harding CL Quach D et al.

Quelle: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Nov 05; Vol. 69 (11), pp. e0098025. Date of Electronic Publication: 2025 Sep 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

MeSH-Schlagworte: Mycobacterium tuberculosis*/drug effects , Mycobacterium tuberculosis*/genetics , Mycobacterium tuberculosis*/metabolism , Bacterial Proteins*/genetics , Bacterial Proteins*/antagonists & inhibitors , Bacterial Proteins*/metabolism , Antitubercular Agents*/pharmacology , Antitubercular Agents*/chemistry , Amides*/pharmacology , Amides*/chemistry , Pyrimidines*/pharmacology , Pyrimidines*/chemistry, Cell Wall/drug effects ; Cell Wall/metabolism ; Microbial Sensitivity Tests ; Mutation ; Humans ; Adenosine Triphosphate/metabolism ; Membrane Transport Proteins

Effects of Rock Inhibitor (Y-27632) on the Corneal Endothelium in Dogs Undergoing Phacoemulsification: A Pilot Study.

Autoren: Rosa Filezio M R M Pádua I Madruga G et al.

Quelle: Veterinary ophthalmology [Vet Ophthalmol] 2025 Nov; Vol. 28 (6), pp. 956-965. Date of Electronic Publication: 2025 Mar 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: England NLM ID: 100887377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-5224 (Electronic) Linking ISSN: 14635216 NLM ISO Abbreviation: Vet Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Phacoemulsification*/veterinary , Pyridines*/pharmacology , Pyridines*/therapeutic use , Amides*/pharmacology , Amides*/therapeutic use , Endothelium, Corneal*/drug effects , rho-Associated Kinases*/antagonists & inhibitors , Dog Diseases*/surgery , Cataract*/veterinary, Animals ; Dogs ; Pilot Projects ; Female ; Male

Synthesis, computational, and biological evaluation of novel indolophenyl carboxamides as potential antimalarial agents.

Autoren: Mondal P Tudu AK Tiwari N et al.

Quelle: Future medicinal chemistry [Future Med Chem] 2025 Nov; Vol. 17 (22), pp. 1-17. Date of Electronic Publication: 2025 Oct 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

MeSH-Schlagworte: Antimalarials*/pharmacology , Antimalarials*/chemical synthesis , Antimalarials*/chemistry , Plasmodium falciparum*/drug effects , Indoles*/chemistry , Indoles*/pharmacology , Indoles*/chemical synthesis , Amides*/pharmacology , Amides*/chemistry , Amides*/chemical synthesis, Humans ; Structure-Activity Relationship ; Parasitic Sensitivity Tests ; Tetrahydrofolate Dehydrogenase/metabolism ; Tetrahydrofolate Dehydrogenase/chemistry ; Molecular Structure ; Molecular Docking Simulation ; Dose-Response Relationship, Drug

"Molecular Docking and Dynamic Studies of Amide Derivatives from Cinnamic Acid with Potential Anti-Dengue Virus Activity".

Autoren: Cárdenas-Granados LA Hernández-Serda MA Villegas-Solís OJ et al.

Quelle: ChemistryOpen [ChemistryOpen] 2025 Nov; Vol. 14 (11), pp. e202500107. Date of Electronic Publication: 2025 Jul 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101594811 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2191-1363 (Electronic) Linking ISSN: 21911363 NLM ISO Abbreviation: ChemistryOpen Subsets: MEDLINE

MeSH-Schlagworte: Dengue Virus*/drug effects , Antiviral Agents*/chemistry , Antiviral Agents*/pharmacology , Molecular Docking Simulation* , Amides*/chemistry , Amides*/pharmacology , Cinnamates*/chemistry , Cinnamates*/pharmacology, Molecular Dynamics Simulation ; Viral Envelope Proteins/metabolism ; Viral Envelope Proteins/antagonists & inhibitors ; Viral Envelope Proteins/chemistry ; Humans

Undescribed Alkamides From Echinacea purpurea and Echinacea angustifolia: Chemical Composition and Anti-inflammatory Activity.

Autoren: Osman A Ali Z Pandey P et al.

Quelle: Chemistry & biodiversity [Chem Biodivers] 2025 Nov; Vol. 22 (11), pp. e00407. Date of Electronic Publication: 2025 Jul 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE

MeSH-Schlagworte: Echinacea*/chemistry , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/chemistry , Anti-Inflammatory Agents*/isolation & purification , Amides*/chemistry , Amides*/pharmacology , Amides*/isolation & purification, Mice ; Animals ; RAW 264.7 Cells ; Lipopolysaccharides/pharmacology ; Lipopolysaccharides/antagonists & inhibitors ; Nitric Oxide Synthase Type II/antagonists & inhibitors ; Nitric Oxide Synthase Type II/metabolism ; Macrophages/drug effects ; Macrophages/metabolism ; Plant Roots/chemistry ; Plant Roots/metabolism ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Extracts/isolation & purification ; Molecular Structure ; Cell Survival/drug effects ; Structure-Activity Relationship ; Dose-Response Relationship, Drug