Search Results - "ALPHA-RECEPTOR"

Prediction of compounds from breadfruit plants (Artocarpus altilis) as alpha estrogen receptor agonists for novel breast cancer anticancer therapy: an in silico approach

Authors: N. Su’aida R. R. Pratama A. Fadillah et al.

Source: Сибирский онкологический журнал, Vol 24, Iss 2, Pp 68-78 (2025)

Subject Terms: breast cancer, in silico, estrogen alpha receptor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, breadfruit plant, RC254-282

Access URL: https://doaj.org/article/a88db70938834a16a894e1dc64f77c82

Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity

Authors: Amy Dashwood Ntombizodwa Makuyana Rob van der Kant et al.

Contributors: Amy Dashwood Ntombizodwa Makuyana Rob van der Kant et al.

Source: Comput Struct Biotechnol J
Computational and Structural Biotechnology Journal, Vol 27, Iss, Pp 1112-1123 (2025)

Subject Terms: Biochemistry & Molecular Biology, 3101 Biochemistry and cell biology, Science & Technology, COMPLEX, PREDICTION, 0103 Numerical and Computational Mathematics, 4601 Applied computing, SEQUENCE, HUMAN IL-2, Biotechnology & Applied Microbiology, ALPHA-RECEPTOR, T-CELLS, Interleukin-2, INTERLEUKIN-2 THERAPY, Protein engineering, PROTEIN AGGREGATION, Life Sciences & Biomedicine, Cytokine, IN-VIVO, TP248.13-248.65, 0802 Computation Theory and Mathematics, Biotechnology, Research Article

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/40190571
https://doaj.org/article/bbf5a2197aa04d7885455a6e9ab2ddf3

Type 1 interferon signalling orchestrated by gut microbiota suppresses IgE-mediated anaphylaxis associated with vitamin D3 signalling

Authors: Bangtao Chen, PhD Tingting Song, MD Fei Hao, PhD et al.

Source: World Allergy Organization Journal, Vol 18, Iss 8, Pp 101089- (2025)

Subject Terms: Anaphylaxis, Gut microbiota, Type 1 interferon, Vitamin D3, IFN1 alpha receptor subunit 1, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1939455125000663; https://doaj.org/toc/1939-4551

Access URL: https://doaj.org/article/ee1ade961afc4d01aced5bf649d33536

STables (S1-S14 Tables).

Authors: Bohao Wu Chirag M. Vyas Adrián A. Medina et al.

Subject Terms: Medicine, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Mathematical Sciences not elsewhere classified, women &# 8217, selected inflammatory biomarkers, nurses &# 8217, master &# 8217, limited statistical power, included 329 women, four inflammatory biomarkers, gestational risk factor, crp ), interleukin, chronic systemic inflammation, alpha receptor 2, 55 contemplating pregnancy, statistically significant associations, hispanic white women, health study 3, 26 pregnant ), 28 contemplating pregnancy, pregnancy , contemplating pregnancy

Availability: https://doi.org/10.1371/journal.pone.0331905.s001
https://figshare.com/articles/journal_contribution/STables_S1-S14_Tables_/30080105

Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains

Authors: Marjolein C. Stip J. H. Marco Jansen Maaike Nederend et al.

Contributors: Marjolein C. Stip J. H. Marco Jansen Maaike Nederend et al.

Source: Cancer Immunol Immunother

Subject Terms: Male, Cancer Research, Fc alpha receptor, Neutrophils, Research, Immunology, Mice, Transgenic, Mice, SCID, Receptors, Fc, 3. Good health, Immunoglobulin A, Mice, Inbred C57BL, Mice, Oncology, Genetically engineered mouse model, Neoplasms, Journal Article, Immunology and Allergy, Humans, Animals, Female, Immunotherapy

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Access URL: https://pubmed.ncbi.nlm.nih.gov/37338671
https://dspace.library.uu.nl/handle/1874/449390

Tumor necrosis factor receptor signaling modulates carcinogenesis in a mouse model of breast cancer

Authors: He, Ling Bhat, Kruttika Duhacheck-Muggy, Sara et al.

Source: Neoplasia. 23(2)

Subject Terms: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Genetics, Women's Health, Breast Cancer, Alleles, Animals, Biomarkers, Breast Neoplasms, Cell Line, Tumor, Cell Transformation, Neoplastic, Cytokines, Disease Models, Animal, Disease Susceptibility, Female, Humans, Immunohistochemistry, Mice, Mice, Knockout, NF-kappa B, Organogenesis, Proteomics, Receptors, Tumor Necrosis Factor, Receptors, Tumor Necrosis Factor, Type II, Signal Transduction, Breast cancer, Mammary epithelial stem cells, Tumor necrosis factor alpha receptor, NF-kappa B signaling, NF-κB signaling, Clinical Sciences, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis

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Access URL: https://escholarship.org/uc/item/3mt428qb
https://escholarship.org/content/qt3mt428qb/qt3mt428qb.pdf

Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG

Authors: Brandsma, Arianne M. Bondza, Sina Evers, Mitchell et al.

Source: Frontiers in Immunology. 10

Subject Terms: IgA, immunotherapy, neutrophil, ADCC, cancer, Fc alpha receptor I, CD89, signaling

File Description: electronic

Access URL: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382553
https://doi.org/10.3389/fimmu.2019.00704

Synthesis and computational insights of hybrid heterocyclic bis-chalcone compounds and their cytotoxic effects against breast cancer cells

Authors: Sadiq Abubakar Melati Khairuddean Noor Zafirah Ismail et al.

Source: Results in Chemistry, Vol 7, Iss , Pp 101464- (2024)

Subject Terms: Cytotoxicity, Computational analysis, Estrogen alpha receptor, Bis-chalcone, ADME properties, Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715624001607; https://doaj.org/toc/2211-7156

Access URL: https://doaj.org/article/80b257dd69794fe2a5a9589505bc098a

Hypotension with and Without Hypertensive Episodes During Endoscopic Adrenalectomy for Pheochromocytoma or Paraganglioma—Should Perioperative Treatment Be Individualized?

Authors: Akos Tiboldi Jonas Gernhold Christian Scheuba et al.

Source: Journal of Clinical Medicine ; Volume 13 ; Issue 23 ; Pages: 7054

Subject Terms: pheochromocytoma, hypotension, alpha-receptor blocker, adrenalectomy, risk factor

File Description: application/pdf

Relation: General Surgery; https://dx.doi.org/10.3390/jcm13237054

Availability: https://doi.org/10.3390/jcm13237054

TGFB2 mRNA Levels Prognostically Interact with Interferon-Alpha Receptor Activation of IRF9 and IFI27, and an Immune Checkpoint LGALS9 to Impact Overall Survival in Pancreatic Ductal Adenocarcinoma

Authors: Sanjive Qazi Vuong Trieu

Source: International Journal of Molecular Sciences ; Volume 25 ; Issue 20 ; Pages: 11221

Subject Terms: PDAC, pancreatic cancer, TGF beta, TGFB2, interferon-alpha receptor, RNAseq, mRNA, tumor microenvironment, biomarkers, TAMs, immune checkpoint

Subject Geographic: agris

File Description: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms252011221

Availability: https://doi.org/10.3390/ijms252011221

Effects of bone marrow mesenchymal stem cell transplantation on tumor necrosis factor-alpha receptor 1 expression, granulosa cell apoptosis, and folliculogenesis repair in endometriosis mouse models

Authors: Sri Ratna Dwiningsih Soehartono Darmosoekarto Hendy Hendarto et al.

Source: Vet World
Veterinary World, Vol 14, Iss 7, Pp 1788-1796 (2021)

Subject Terms: endometriosis, Veterinary medicine, apoptosis, bone marrow mesenchymal stem cells, R Medicine (General), SF1-1100, Animal culture, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, granulosa cells, folliculogenesis, tumor necrosis factor-alpha receptor 1, RG Gynecology and obstetrics, SF600-1100, Research Article

File Description: text

Access URL: http://www.veterinaryworld.org/Vol.14/July-2021/9.pdf
https://pubmed.ncbi.nlm.nih.gov/34475699
https://doaj.org/article/d7f084c98c7a41fdad4bf43e35c622a4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404130
http://www.veterinaryworld.org/Vol.14/July-2021/9.pdf

Curcumin assists anti-EV71 activity of IFN-α by inhibiting IFNAR1 reduction in SH-SY5Y cells

Authors: Yanfang Wang Kena Dan Xiaoling Xue et al.

Source: Gut Pathogens, Vol 14, Iss 1, Pp 1-9 (2022)

Subject Terms: Enterovirus 71(EV71), Interferon alpha receptor 1 (IFNAR1), Curcumin, Interferon-α (IFN-α), Ubiquitin–proteasome, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4749

Access URL: https://doaj.org/article/e2cafc15c5514b40adc1723da6658668

Antagonizing FcαR1 (CD89) as treatment in IgA-mediated chronic inflammation and autoimmunity

Authors: Myrthe A. M. van Delft Esil Aleyd Richard van der Mast et al.

Source: Front Immunol
Frontiers in Immunology, Vol 14 (2023)
van Delft, M A M, Aleyd, E, Mast, R V D, de Jong, N, Boon, L, Simons, P J & van Egmond, M 2023, 'Antagonizing FcαR1 (CD89) as treatment in IgA-mediated chronic inflammation and autoimmunity', Frontiers in Immunology, vol. 14, 1118539, pp. 1118539. https://doi.org/10.3389/fimmu.2023.1118539, https://doi.org/10.3389/fimmu.2023.1118539

Subject Terms: Inflammation, Fc alpha receptor (FcαRI), autoimmunity, Immunology, Autoimmunity, immunoglobulin A, RC581-607, Leukotriene B4, 3. Good health, Immunoglobulin A, neutrophils (PMNs), Mice, Lactoferrin, Animals, chronic-inflammation (CI), Immunologic diseases. Allergy

Access URL: https://pubmed.ncbi.nlm.nih.gov/37081893
https://doaj.org/article/1896f0aee4b44201819b5da2463403ec
https://research.vumc.nl/en/publications/2a114001-c100-4863-8753-0bfc8de5cbbf

Approach to the Patient: Perioperative Management of the Patient with Pheochromocytoma or Sympathetic Paraganglioma: Perioperative Management of the Patient with Pheochromocytoma or Sympathetic Paraganglioma

Authors: Jacques W.M. Lenders Michiel N. Kerstens Henri J L M Timmers et al.

Source: Journal of Clinical Endocrinology and Metabolism, 105, 9

Subject Terms: sympathetic paraganglioma, Adrenal Gland Neoplasms, Pheochromocytoma, PREOPERATIVE PREPARATION, Drug Administration Schedule, Perioperative Care, Paraganglioma, Young Adult, 03 medical and health sciences, Radboudumc 16: Vascular damage RIHS: Radboud Institute for Health Sciences, 0302 clinical medicine, Patient-Centered Care, Humans, Internal Medicine - Radboud University Medical Center, Perioperative Period, CALCIUM-CHANNEL BLOCKERS, HALOTHANE ANESTHESIA, Antihypertensive Agents, Radboudumc 16: Vascular damage RIMLS: Radboud Institute for Molecular Life Sciences, ANESTHETIC MANAGEMENT, Paraganglia, Chromaffin, HEMODYNAMIC INSTABILITY, alpha-receptor blockade, perioperative management, HYPERTENSIVE RESPONSE, pheochromocytoma, Combined Modality Therapy, EUROPEAN-SOCIETY, 3. Good health, ALPHA-METHYLTYROSINE, Autonomic Nervous System Diseases, LAPAROSCOPIC ADRENALECTOMY, HISTAMINE-RELEASE, Female

Access URL: https://pure.rug.nl/ws/files/130596087/dgaa441.pdf
https://pubmed.ncbi.nlm.nih.gov/32726444
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/225527
https://doi.org/10.1210/clinem/dgaa441
https://research.rug.nl/en/publications/18f7d2c5-e924-48c0-a693-4945d62b1ada
https://hdl.handle.net/11370/18f7d2c5-e924-48c0-a693-4945d62b1ada
https://doi.org/10.1210/clinem/dgaa441
https://academic.oup.com/jcem/article-abstract/105/9/3088/5868468
https://research.rug.nl/en/publications/approach-to-the-patient-perioperative-management-of-the-patient-w
http://www.ncbi.nlm.nih.gov/pubmed/32726444
https://www.rug.nl/research/portal/publications/approach-to-the-patient(18f7d2c5-e924-48c0-a693-4945d62b1ada).html
https://pubmed.ncbi.nlm.nih.gov/32726444/
https://www.ncbi.nlm.nih.gov/pubmed/32726444
https://hdl.handle.net/2066/225527
https://repository.ubn.ru.nl//bitstream/handle/2066/225527/225527.pdf

Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer

Authors: Ling He Kruttika Bhat Sara Duhacheck-Muggy et al.

Source: Neoplasia
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 197-209 (2021)
Neoplasia, vol 23, iss 2

Subject Terms: Proteomics, 0301 basic medicine, Organogenesis, Clinical sciences, Cell Transformation, Receptors, Tumor Necrosis Factor, Mice, Breast cancer, Receptors, Mammary epithelial stem cells, RC254-282, Cancer, Tumor necrosis factor alpha receptor, Mice, Knockout, 2. Zero hunger, 0303 health sciences, Tumor, NF-kappa B, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, 3. Good health, Cell Transformation, Neoplastic, NF-κB signaling, Cytokines, Female, Disease Susceptibility, Signal Transduction, Original article, Knockout, Oncology and Carcinogenesis, Clinical Sciences, Breast Neoplasms, Type II, Cell Line, NF-kappa B signaling, 03 medical and health sciences, Cell Line, Tumor, Breast Cancer, Genetics, Animals, Humans, Receptors, Tumor Necrosis Factor, Type II, Oncology & Carcinogenesis, Alleles, Neoplastic, Biomedical and Clinical Sciences, Animal, Oncology and carcinogenesis, Disease Models, Animal, Disease Models, Women's Health, Tumor Necrosis Factor, Biomarkers

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Access URL: https://europepmc.org/articles/pmc7779542?pdf=render
https://pubmed.ncbi.nlm.nih.gov/33383310
https://doaj.org/article/5f3b6de0ed604aa2bc4f1d4989e411f7
https://www.biorxiv.org/content/10.1101/2020.03.12.989335v1
https://biorxiv.org/content/10.1101/2020.03.12.989335v1.full.pdf
https://www.sciencedirect.com/science/article/abs/pii/S1476558620301883
https://pubmed.ncbi.nlm.nih.gov/33383310/
https://escholarship.org/uc/item/3mt428qb
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779542
https://www.scilit.net/article/d7aeb3696c63328a1f559bdc750cc121
https://www.sciencedirect.com/science/article/pii/S1476558620301883
https://escholarship.org/uc/item/3mt428qb
https://escholarship.org/content/qt3mt428qb/qt3mt428qb.pdf

Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains

Authors: Stip, Marjolein C. Jansen, J. H.Marco Nederend, Maaike et al.

Contributors: Stip, Marjolein C. Jansen, J. H.Marco Nederend, Maaike et al.

Subject Terms: Fc alpha receptor, Genetically engineered mouse model, Immunoglobulin A, Immunotherapy, Neutrophils, Oncology, Cancer Research, Immunology and Allergy, Immunology, Journal Article

File Description: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/449390

Availability: https://dspace.library.uu.nl/handle/1874/449390

An Attempt to Identify the Medaka Receptor for Somatolactin Alpha Using a Reverse Genetics Approach

Authors: Yuko Moroki Mamiko Komori Yuko Ogawa et al.

Source: Genes, Vol 14, Iss 4, p 796 (2023)

Subject Terms: medaka fish, phylogenetic reconstruction, genome editing, frameshift mutations, growth hormone receptor, somatolactin alpha receptor, Genetics, QH426-470

Relation: https://www.mdpi.com/2073-4425/14/4/796; https://doaj.org/toc/2073-4425; https://doaj.org/article/e60340a5fc4f4b00bc022738f1c6f431

Availability: https://doi.org/10.3390/genes14040796
https://doaj.org/article/e60340a5fc4f4b00bc022738f1c6f431

IgA - The art of balancing between host protection and auto-immunity

Authors: Breedveld, Anne Charlotte

Source: Breedveld , A C 2021 , ' IgA - The art of balancing between host protection and auto-immunity ' , Dr. , Vrije Universiteit Amsterdam , s.l. .

Subject Terms: IgA, Immunoglobuline A, Fc alpha receptor, CD89, vaginale microbiota, reuma, serum IgA, dendritische cellen, neutrofielen, Immunoglobulin A, vaginal microbiota, rheumatoid artritis, dendritic cells, neutrophils

File Description: application/pdf; image/jpeg

Relation: urn:ISBN:9789464165531

Availability: https://research.vu.nl/en/publications/3da43fe4-0146-4cce-b89a-ffb3f2f53633
https://hdl.handle.net/1871.1/3da43fe4-0146-4cce-b89a-ffb3f2f53633
https://research.vu.nl/ws/files/131185443/A%20C%20%20Breedveld%20-%20thesis.pdf
https://research.vu.nl/ws/files/131185445/A%20C%20%20Breedveld%20-%20cover.jpg
https://research.vu.nl/ws/files/131185447/A%20C%20%20Breedveld%20-%20title_page.pdf

Characteristics of study participants contemplating pregnancy in the total sample (n = 204) and by severity levels of childhood maltreatment, Nurses’ Health Study 3.

Authors: Bohao Wu Chirag M. Vyas Adrián A. Medina et al.

Subject Terms: Medicine, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Mathematical Sciences not elsewhere classified, women &# 8217, selected inflammatory biomarkers, nurses &# 8217, master &# 8217, limited statistical power, included 329 women, four inflammatory biomarkers, gestational risk factor, crp ), interleukin, chronic systemic inflammation, alpha receptor 2, 55 contemplating pregnancy, statistically significant associations, hispanic white women, health study 3, 26 pregnant ), 28 contemplating pregnancy, pregnancy , contemplating pregnancy

Relation: https://figshare.com/articles/dataset/Characteristics_of_study_participants_contemplating_pregnancy_in_the_total_sample_n_204_and_by_severity_levels_of_childhood_maltreatment_Nurses_Health_Study_3_/30080117

Availability: https://doi.org/10.1371/journal.pone.0331905.t001
https://figshare.com/articles/dataset/Characteristics_of_study_participants_contemplating_pregnancy_in_the_total_sample_n_204_and_by_severity_levels_of_childhood_maltreatment_Nurses_Health_Study_3_/30080117

S2 Fig. Biomarker concentrations by severity levels of childhood maltreatment among pregnant participants (n = 124), Nurses’ Health Study 3.

Authors: Bohao Wu Chirag M. Vyas Adrián A. Medina et al.

Subject Terms: Medicine, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Mathematical Sciences not elsewhere classified, women &# 8217, selected inflammatory biomarkers, nurses &# 8217, master &# 8217, limited statistical power, included 329 women, four inflammatory biomarkers, gestational risk factor, crp ), interleukin, chronic systemic inflammation, alpha receptor 2, 55 contemplating pregnancy, statistically significant associations, hispanic white women, health study 3, 26 pregnant ), 28 contemplating pregnancy, pregnancy , contemplating pregnancy

Relation: https://figshare.com/articles/figure/S2_Fig_Biomarker_concentrations_by_severity_levels_of_childhood_maltreatment_among_pregnant_participants_n_124_Nurses_Health_Study_3_/30080111

Availability: https://doi.org/10.1371/journal.pone.0331905.s003
https://figshare.com/articles/figure/S2_Fig_Biomarker_concentrations_by_severity_levels_of_childhood_maltreatment_among_pregnant_participants_n_124_Nurses_Health_Study_3_/30080111