Search Results - "ADIPOGENESIS"

The cAMP-phosphodiesterase PDE4B2 controls peroxisome proliferator-activated receptor γ expression and the initiation of adipogenesis in 3T3-L1 cells.

Authors: Fiedler E Boyd A Irelan D et al.

Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2025 Dec 01; Vol. 329 (6), pp. E874-E887. Date of Electronic Publication: 2025 Oct 13.

Publication Type: Journal Article

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE

MeSH Terms: Adipogenesis*/genetics , Adipogenesis*/drug effects , PPAR gamma*/metabolism , PPAR gamma*/genetics , Cyclic Nucleotide Phosphodiesterases, Type 4*/genetics , Cyclic Nucleotide Phosphodiesterases, Type 4*/metabolism , Adipocytes*/metabolism, Animals ; Mice ; 3T3-L1 Cells ; Cell Differentiation/genetics ; CCAAT-Enhancer-Binding Protein-alpha/metabolism ; CCAAT-Enhancer-Binding Protein-alpha/genetics ; Male ; CCAAT-Enhancer-Binding Proteins/metabolism ; CCAAT-Enhancer-Binding Proteins/genetics

Capsaicin camphor and caffeic acid reduce adipogenesis and promote lipolysis with TRPV1 involvement.

Authors: Ali U Wasner F Fan J et al.

Source: Scientific reports [Sci Rep] 2025 Dec 02; Vol. 15 (1), pp. 43024. Date of Electronic Publication: 2025 Dec 02.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Caffeic Acids*/pharmacology , Lipolysis*/drug effects , Adipogenesis*/drug effects , TRPV Cation Channels*/metabolism , TRPV Cation Channels*/genetics , Capsaicin*/pharmacology , Camphor*/pharmacology, Humans ; Adipocytes/drug effects ; Adipocytes/metabolism ; Gigantism/metabolism ; Gigantism/pathology ; Gigantism/drug therapy ; Gigantism/genetics ; Genetic Diseases, X-Linked/metabolism ; Genetic Diseases, X-Linked/pathology ; Genetic Diseases, X-Linked/genetics ; PPAR gamma/metabolism ; PPAR gamma/genetics ; Cell Survival/drug effects ; Arrhythmias, Cardiac ; Heart Defects, Congenital ; Intellectual Disability

SCR Disease Name: Simpson-Golabi-Behmel syndrome

Identification of an Intracellular Role for Complement Factor D: Lipid Droplet Biogenesis in Differentiating Adipocytes.

Authors: Khaledian B Yamagata K Kato T et al.

Source: Comprehensive Physiology [Compr Physiol] 2025 Dec; Vol. 15 (6), pp. e70067.

Publication Type: Journal Article

Journal Info: Country of Publication: United States NLM ID: 101574442 Publication Model: Print Cited Medium: Internet ISSN: 2040-4603 (Electronic) Linking ISSN: 20404603 NLM ISO Abbreviation: Compr Physiol Subsets: MEDLINE

MeSH Terms: Complement Factor D*/metabolism , Complement Factor D*/genetics , Adipocytes*/metabolism , Adipocytes*/cytology , Lipid Droplets*/metabolism , Adipogenesis*/physiology, Animals ; Mice ; Mice, Knockout ; Cell Differentiation/physiology ; Cells, Cultured ; Mice, Inbred C57BL

Discovery of a bell-shaped dose response curve to melanin-concentrating hormone in the 3T3-L1 adipocyte model: low-dose MCH facilitates adipogenesis.

Authors: Cook LB King CM Abdullah HY

Source: Adipocyte [Adipocyte] 2025 Dec; Vol. 14 (1), pp. 2594882. Date of Electronic Publication: 2025 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101567863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-397X (Electronic) Linking ISSN: 21623945 NLM ISO Abbreviation: Adipocyte Subsets: MEDLINE

MeSH Terms: Hypothalamic Hormones*/pharmacology , Hypothalamic Hormones*/metabolism , Melanins*/pharmacology , Melanins*/metabolism , Adipocytes*/metabolism , Adipocytes*/drug effects , Adipocytes*/cytology , Pituitary Hormones*/pharmacology , Pituitary Hormones*/metabolism , Adipogenesis*/drug effects, Animals ; Mice ; 3T3-L1 Cells ; Signal Transduction/drug effects ; Lipolysis/drug effects ; Dose-Response Relationship, Drug ; Receptors, Somatostatin/metabolism

Molecular mechanisms of propolis in adipogenesis, lipid metabolism and white adipose tissue Browning: a systematic review of preclinical studies.

Authors: Megantara I Karisa P Pakpahan WI et al.

Source: Adipocyte [Adipocyte] 2025 Dec; Vol. 14 (1), pp. 2576894. Date of Electronic Publication: 2025 Oct 18.

Publication Type: Journal Article; Systematic Review; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101567863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-397X (Electronic) Linking ISSN: 21623945 NLM ISO Abbreviation: Adipocyte Subsets: MEDLINE

MeSH Terms: Propolis*/pharmacology , Adipogenesis*/drug effects , Lipid Metabolism*/drug effects , Adipose Tissue, White*/metabolism , Adipose Tissue, White*/drug effects , Adipose Tissue, Brown*/metabolism , Adipose Tissue, Brown*/drug effects, Animals ; Humans

Activation of CXCR7 exerts an inhibitory effect on adipogenesis through regulation of β-arrestin2/Wnt and AKT signalling.

Authors: Sun S Arif Aslam M Ma EB et al.

Source: Adipocyte [Adipocyte] 2025 Dec; Vol. 14 (1), pp. 2490258. Date of Electronic Publication: 2025 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101567863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-397X (Electronic) Linking ISSN: 21623945 NLM ISO Abbreviation: Adipocyte Subsets: MEDLINE

MeSH Terms: Receptors, CXCR*/metabolism , Receptors, CXCR*/genetics , beta-Arrestin 2*/metabolism , beta-Arrestin 2*/genetics , Adipogenesis*/genetics , Proto-Oncogene Proteins c-akt*/metabolism , Wnt Signaling Pathway*, Animals ; Mice ; Adipocytes/metabolism ; Adipocytes/cytology ; Chemokine CXCL12/metabolism ; Chemokine CXCL12/genetics ; 3T3-L1 Cells ; Receptors, CXCR4/metabolism ; Receptors, CXCR4/genetics ; Mice, Inbred C57BL ; Signal Transduction ; Male ; Cell Differentiation

METTL14 and WTAP play a crucial role in the regulation of bovine preadipocyte differentiation.

Authors: Liu J Ma C Cheng Y et al.

Source: Animal biotechnology [Anim Biotechnol] 2025 Dec; Vol. 36 (1), pp. 2476531. Date of Electronic Publication: 2025 Mar 17.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9011409 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2378 (Electronic) Linking ISSN: 10495398 NLM ISO Abbreviation: Anim Biotechnol Subsets: MEDLINE

MeSH Terms: Adipocytes*/cytology , Adipocytes*/physiology , Adipocytes*/metabolism , Cell Differentiation*/genetics , Cell Differentiation*/physiology , Methyltransferases*/genetics , Methyltransferases*/metabolism , Adipogenesis*/genetics , Adipogenesis*/physiology, Animals ; Cattle ; Signal Transduction/genetics ; Gene Knockdown Techniques ; Gene Expression Regulation

Adipogenic dedifferentiation enhances survival of human umbilical cord-derived mesenchymal stem cells under oxidative stress.

Authors: Yuan Y Kuang M Yu T et al.

Source: Adipocyte [Adipocyte] 2025 Dec; Vol. 14 (1), pp. 2467150. Date of Electronic Publication: 2025 Feb 20.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101567863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-397X (Electronic) Linking ISSN: 21623945 NLM ISO Abbreviation: Adipocyte Subsets: MEDLINE

MeSH Terms: Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/metabolism , Oxidative Stress* , Umbilical Cord*/cytology , Adipogenesis* , Cell Dedifferentiation*, Humans ; Cell Survival ; Cell Differentiation ; Apoptosis ; Cells, Cultured ; Cell Proliferation ; Autophagy

A triterpene-enriched natural extract from Eucalyptus tereticornis modulates the expression of genes involved in adipogenesis, lipolysis, and extracellular matrix remodeling in a primary human and mouse cell line adipocyte.

Authors: Acin S Mejia-Garcia A Fernandez GJ et al.

Source: Pharmaceutical biology [Pharm Biol] 2025 Dec; Vol. 63 (1), pp. 374-386. Date of Electronic Publication: 2025 May 18.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

MeSH Terms: Adipocytes*/drug effects , Adipocytes*/metabolism , Plant Extracts*/pharmacology , Plant Extracts*/isolation & purification , Triterpenes*/pharmacology , Triterpenes*/isolation & purification , Adipogenesis*/drug effects , Adipogenesis*/genetics , Eucalyptus*/chemistry , Lipolysis*/drug effects , Lipolysis*/genetics, Animals ; Humans ; Mice ; Extracellular Matrix/drug effects ; Extracellular Matrix/metabolism ; Extracellular Matrix/genetics ; 3T3-L1 Cells ; Obesity/drug therapy ; Obesity/genetics ; Plant Leaves ; Gene Expression Regulation/drug effects ; Cells, Cultured

miR-6402 targets Bmpr2 and negatively regulates mouse adipogenesis.

Authors: Elsheikh M Sano T Mizokami A et al.

Source: Adipocyte [Adipocyte] 2025 Dec; Vol. 14 (1), pp. 2474114. Date of Electronic Publication: 2025 Mar 03.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101567863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-397X (Electronic) Linking ISSN: 21623945 NLM ISO Abbreviation: Adipocyte Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , MicroRNAs*/metabolism , Adipogenesis*/genetics , Bone Morphogenetic Protein Receptors, Type II*/metabolism , Bone Morphogenetic Protein Receptors, Type II*/genetics, Animals ; Mice ; Male ; Diet, High-Fat ; 3T3-L1 Cells ; Adipose Tissue, White/metabolism ; Adipocytes/metabolism ; Bone Morphogenetic Protein 4/metabolism ; Mice, Inbred C57BL ; Obesity/metabolism ; Obesity/genetics ; Gene Expression Regulation

Nanosphere loaded with curcumin attenuates adipogenesis and lipid metabolism by modulating AKT/mTORC1/PPARγ phosphorylation.

Authors: Park JY Kim RW Lee J et al.

Source: Tissue & cell [Tissue Cell] 2025 Dec; Vol. 97, pp. 103112. Date of Electronic Publication: 2025 Aug 29.

Publication Type: Journal Article

Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE

MeSH Terms: Curcumin*/pharmacology , Curcumin*/chemistry , Adipogenesis*/drug effects , Lipid Metabolism*/drug effects , PPAR gamma*/metabolism , Mechanistic Target of Rapamycin Complex 1*/metabolism , Nanospheres*/chemistry , Proto-Oncogene Proteins c-akt*/metabolism, Animals ; Mice ; 3T3-L1 Cells ; Phosphorylation/drug effects ; Obesity/drug therapy ; Obesity/pathology ; Obesity/metabolism ; Male ; Adipocytes/drug effects ; Adipocytes/metabolism ; Diet, High-Fat ; Mice, Inbred C57BL

The MLL4: Roles in cell differentiation, adipogenesis and cancer.

Authors: Zhang Y Lv K Ma X et al.

Source: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 3), pp. 117371. Date of Electronic Publication: 2025 Sep 25.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

MeSH Terms: Adipogenesis*/physiology , Neoplasms*/metabolism , Neoplasms*/genetics , Neoplasms*/pathology , Histone-Lysine N-Methyltransferase*/metabolism , Histone-Lysine N-Methyltransferase*/genetics , Histone-Lysine N-Methyltransferase*/chemistry , Cell Differentiation*/physiology , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics , DNA-Binding Proteins*/chemistry, Humans ; Animals

Virginianoside A, a new steroidal alkaloid saponin from Solanum virginianum: Isolation, structure elucidation and anti-adipogenic activity.

Authors: Vishwakarma A Gupta J Singh A et al.

Source: Fitoterapia [Fitoterapia] 2025 Dec; Vol. 187, pp. 106897. Date of Electronic Publication: 2025 Sep 24.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

MeSH Terms: Saponins*/isolation & purification , Saponins*/pharmacology , Saponins*/chemistry , Solanum*/chemistry , Adipogenesis*/drug effects , Alkaloids*/isolation & purification , Alkaloids*/pharmacology, Animals ; Mice ; Molecular Structure ; 3T3-L1 Cells ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Adipocytes/drug effects

Adipogenic characterization of immortalized CD55 ⁺ progenitor cells from human white adipose tissue.

Authors: Couchet M Gao H Klingelhuber F et al.

Source: Adipocyte [Adipocyte] 2025 Dec; Vol. 14 (1), pp. 2283213. Date of Electronic Publication: 2025 Jun 05.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101567863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-397X (Electronic) Linking ISSN: 21623945 NLM ISO Abbreviation: Adipocyte Subsets: MEDLINE

MeSH Terms: Adipogenesis* , Stem Cells*/metabolism , Stem Cells*/cytology , Adipose Tissue, White*/cytology , Adipose Tissue, White*/metabolism, Humans ; Telomerase/genetics ; Telomerase/metabolism ; Cells, Cultured ; Cell Proliferation ; Adipocytes/metabolism ; Adipocytes/cytology ; Cell Differentiation

Creatine kinase B regulates glycolysis and de novo lipogenesis pathways to control lipid accumulation during adipogenesis.

Authors: Renzi G Higos R Vlassakev I et al.

Source: Cell reports [Cell Rep] 2025 Nov 25; Vol. 44 (11), pp. 116489. Date of Electronic Publication: 2025 Nov 05.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH Terms: Lipogenesis* , Adipogenesis* , Glycolysis* , Lipid Metabolism*, Animals ; Mice ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; 3T3-L1 Cells ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism ; Insulin/metabolism ; Cell Differentiation ; Adipocytes/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Humans ; Transcription Factors/metabolism

Intralipid Infusion to Fetal Sheep (Ovis aries) Promotes Differentiation and Lipid Accumulation of Adipose Tissues.

Authors: Li X Alaniz SM Louey S et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Nov 15; Vol. 39 (21), pp. e71198.

Publication Type: Journal Article

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH Terms: Soybean Oil*/pharmacology , Soybean Oil*/administration & dosage , Adipose Tissue*/metabolism , Adipose Tissue*/drug effects , Lipid Metabolism*/drug effects , Phospholipids*/pharmacology , Phospholipids*/administration & dosage , Cell Differentiation*/drug effects , Fetus*/drug effects , Fetus*/metabolism , Adipogenesis*/drug effects , Fat Emulsions, Intravenous*/pharmacology, Animals ; Sheep ; Emulsions/pharmacology ; Emulsions/administration & dosage ; Female ; Pregnancy

Faecalibacterium prausnitzii alleviates Graves' orbitopathy by modulating short-chain fatty acid (SCFA) metabolism and inhibiting orbital fibrosis and adipogenesis.

Authors: Qi X Zhang J Li Y et al.

Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2025 Nov; Vol. 773, pp. 110588. Date of Electronic Publication: 2025 Aug 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

MeSH Terms: Adipogenesis*/drug effects , Graves Ophthalmopathy*/metabolism , Graves Ophthalmopathy*/pathology , Graves Ophthalmopathy*/microbiology , Graves Ophthalmopathy*/therapy , Fatty Acids, Volatile*/metabolism , Faecalibacterium prausnitzii*/physiology , Orbit*/pathology , Orbit*/metabolism, Animals ; Mice ; Humans ; Fibrosis ; Male ; Gastrointestinal Microbiome ; Female ; Butyrates/metabolism

Melatonin inhibits adipogenesis and enhances osteogenesis of BMSCs through increasing KLF5 expression.

Authors: Wang S Tian C Liu J et al.

Source: Cellular signalling [Cell Signal] 2025 Nov; Vol. 135, pp. 112017. Date of Electronic Publication: 2025 Jul 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

MeSH Terms: Adipogenesis*/drug effects , Kruppel-Like Transcription Factors*/metabolism , Kruppel-Like Transcription Factors*/genetics , Osteogenesis*/drug effects , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/drug effects , Mesenchymal Stem Cells*/cytology , Melatonin*/pharmacology, Animals ; Mice ; Female ; Promoter Regions, Genetic ; Osteoporosis/pathology ; Osteoporosis/metabolism ; Osteoporosis/drug therapy ; Cell Differentiation/drug effects ; Mice, Inbred C57BL ; DNA Methylation/drug effects ; Ovariectomy

Adipose tissue macrophage-derived miR-690 modulates adipocyte precursor cell maintenance and adipogenesis.

Authors: Cunha E Rocha K Tan B Kempf J et al.

Source: Molecular metabolism [Mol Metab] 2025 Nov; Vol. 101, pp. 102246. Date of Electronic Publication: 2025 Sep 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

MeSH Terms: MicroRNAs*/metabolism , MicroRNAs*/genetics , Adipogenesis*/physiology , Adipogenesis*/genetics , Macrophages*/metabolism , Adipocytes*/metabolism , Adipose Tissue*/metabolism, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Obesity/metabolism ; Obesity/genetics ; Adipose Tissue, White/metabolism

Fat Mass and Obesity-Associated Protein-Mediated Adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells Promotes Chemotherapy Resistance in Acute Myeloid Leukemia

Authors: Zhipeng P Lixia K Ling C

Source: Balkan medical journal [Balkan Med J] 2025 Oct 31; Vol. 42 (6), pp. 538-546. Date of Electronic Publication: 2025 Oct 02.

Publication Type: Journal Article

Journal Info: Publisher: Galenos Publishing House Country of Publication: Turkey NLM ID: 101571817 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2146-3131 (Electronic) Linking ISSN: 21463123 NLM ISO Abbreviation: Balkan Med J Subsets: MEDLINE

MeSH Terms: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/physiopathology , Mesenchymal Stem Cells*/drug effects , Mesenchymal Stem Cells*/metabolism , Drug Resistance, Neoplasm*/physiology , Drug Resistance, Neoplasm*/drug effects , Alpha-Ketoglutarate-Dependent Dioxygenase FTO*/analysis , Adipogenesis*/drug effects , Adipogenesis*/physiology, Humans ; Female ; Cell Differentiation/drug effects ; Cell Differentiation/physiology ; Male ; Middle Aged ; Adult