Suchergebnisse - "ACTION potentials"

Assessing NaV1.7 during tonic firing in pig C-nociceptors.

Autoren: Soares S Schmelz M Carr R et al.

Quelle: PloS one [PLoS One] 2025 Dec 03; Vol. 20 (12), pp. e0335081. Date of Electronic Publication: 2025 Dec 03 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: NAV1.7 Voltage-Gated Sodium Channel*/metabolism , Action Potentials*/drug effects , Action Potentials*/physiology , Nerve Fibers, Unmyelinated*/physiology , Nerve Fibers, Unmyelinated*/drug effects , Nerve Fibers, Unmyelinated*/metabolism , Nociceptors*/physiology , Nociceptors*/metabolism , Nociceptors*/drug effects, Animals ; Swine ; Electric Stimulation ; Tetrodotoxin/pharmacology ; Male

Repeated Morphine Exposure Reversibly Impairs Spike Generation and Repetitive Firing in a Functionally Distinct Subpopulation of Orexin Neurons.

Autoren: Berry EA Huhulea EN Ishibashi M et al.

Quelle: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Dec 03; Vol. 45 (49). Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Orexins* , Neurons*/drug effects , Neurons*/physiology , Morphine*/pharmacology , Morphine*/administration & dosage , Action Potentials*/drug effects , Action Potentials*/physiology , Neuropeptides*/metabolism , Neuropeptides*/genetics , Analgesics, Opioid*/pharmacology, Animals ; Male ; Mice ; Mice, Transgenic ; Mice, Inbred C57BL

Strategies for prolonging ventricular action potential duration without increasing transmural dispersion of repolarization.

Autoren: Cabo C; Department of Computer Systems, New York City College of Technology, New York, New York, USA.; Graduate Center, City University of New York, New York, New York, USA.

Quelle: Physiological reports [Physiol Rep] 2025 Dec; Vol. 13 (23), pp. e70693.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM ID: 101607800 Publication Model: Print Cited Medium: Internet ISSN: 2051-817X (Electronic) Linking ISSN: 2051817X NLM ISO Abbreviation: Physiol Rep Subsets: MEDLINE

MeSH-Schlagworte: Action Potentials*/drug effects , Action Potentials*/physiology , Models, Cardiovascular* , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/physiology , Anti-Arrhythmia Agents*/pharmacology, Humans ; Ion Channels/metabolism ; Computer Simulation ; Heart Ventricles/drug effects ; Arrhythmias, Cardiac/physiopathology

Contribution of chloride channels to the action potential and contraction in human myometrium during labour.

Autoren: Parkington HC Siriwardhana RE Tonta MA et al.

Quelle: British journal of pharmacology [Br J Pharmacol] 2025 Dec; Vol. 182 (23), pp. 5748-5761. Date of Electronic Publication: 2025 Jul 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Myometrium*/physiology , Myometrium*/drug effects , Myometrium*/metabolism , Chloride Channels*/metabolism , Chloride Channels*/physiology , Chloride Channels*/antagonists & inhibitors , Labor, Obstetric*/physiology , Uterine Contraction*/drug effects , Uterine Contraction*/physiology , Action Potentials*/drug effects , Action Potentials*/physiology , Neoplasm Proteins*/metabolism , Neoplasm Proteins*/antagonists & inhibitors, Humans ; Female ; Anoctamin-1 ; Pregnancy ; Oxytocin/pharmacology ; Adult ; In Vitro Techniques

Nicotinic Modulation of Fast-Spiking Neurons in Rat Somatosensory Cortex across Development.

Autoren: Haga CW Koenig J Cramer N et al.

Quelle: ENeuro [eNeuro] 2025 Nov 26; Vol. 12 (11). Date of Electronic Publication: 2025 Nov 26 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

MeSH-Schlagworte: Somatosensory Cortex*/drug effects , Somatosensory Cortex*/growth & development , Somatosensory Cortex*/metabolism , Somatosensory Cortex*/cytology , Nicotine*/pharmacology , Neurons*/drug effects , Neurons*/physiology , Neurons*/metabolism , Receptors, Nicotinic*/metabolism , Nicotinic Agonists*/pharmacology , Action Potentials*/drug effects , Action Potentials*/physiology, Animals ; Male ; Female ; Rats ; Rats, Sprague-Dawley

Collapsing Perisomatic Inhibition Leads to Epileptic Fast-Ripple Oscillations Caused by Pseudosynchronous Firing of CA3 Pyramidal Neurons.

Autoren: Schlingloff D Freund TF Hangya B et al.

Quelle: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Nov 12; Vol. 45 (46). Date of Electronic Publication: 2025 Nov 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

MeSH-Schlagworte: Pyramidal Cells*/physiology , Pyramidal Cells*/drug effects , CA3 Region, Hippocampal*/physiopathology , CA3 Region, Hippocampal*/physiology , Epilepsy*/physiopathology , Action Potentials*/physiology , Action Potentials*/drug effects , Neural Inhibition*/physiology , Neural Inhibition*/drug effects, Animals ; Mice ; Male ; Female ; Mice, Inbred C57BL

Distinct Patterns of Evoked Firing in Engram and Non-Engram Neurons in the Dentate Gyrus of Hippocampal Slices.

Autoren: Shu WC Jackson MB

Quelle: Hippocampus [Hippocampus] 2025 Nov; Vol. 35 (6), pp. e70049.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: United States NLM ID: 9108167 Publication Model: Print Cited Medium: Internet ISSN: 1098-1063 (Electronic) Linking ISSN: 10509631 NLM ISO Abbreviation: Hippocampus Subsets: MEDLINE

MeSH-Schlagworte: Dentate Gyrus*/physiology , Dentate Gyrus*/cytology , Neurons*/physiology , Neurons*/drug effects , Action Potentials*/physiology , Action Potentials*/drug effects, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Proto-Oncogene Proteins c-fos/genetics ; Proto-Oncogene Proteins c-fos/metabolism

Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.

Autoren: Bjelica B Wohnrade C Osmanovic A et al.

Quelle: European journal of neurology [Eur J Neurol] 2025 Nov; Vol. 32 (11), pp. e70405.

Publikationsart: Journal Article; Multicenter Study; Observational Study

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print Cited Medium: Internet ISSN: 1468-1331 (Electronic) Linking ISSN: 13515101 NLM ISO Abbreviation: Eur J Neurol Subsets: MEDLINE

MeSH-Schlagworte: Oligonucleotides*/therapeutic use , Oligonucleotides*/pharmacology , Action Potentials*/drug effects , Action Potentials*/physiology , Muscular Atrophy, Spinal*/drug therapy , Muscular Atrophy, Spinal*/physiopathology , Spinal Muscular Atrophies of Childhood*/drug therapy , Spinal Muscular Atrophies of Childhood*/physiopathology, Humans ; Female ; Male ; Adult ; Middle Aged ; Ulnar Nerve/physiopathology ; Young Adult ; Median Nerve/physiopathology ; Peroneal Nerve/physiopathology

Compound muscle action potential as an early functional in vivo measure of Sarm1 inhibition after sciatic nerve transection.

Autoren: Hur SK Leahey RR Geringer M et al.

Quelle: Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2025 Nov 01; Vol. 84 (11), pp. 998-1012.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985192R Publication Model: Print Cited Medium: Internet ISSN: 1554-6578 (Electronic) Linking ISSN: 00223069 NLM ISO Abbreviation: J Neuropathol Exp Neurol Subsets: MEDLINE

MeSH-Schlagworte: Armadillo Domain Proteins*/antagonists & inhibitors , Armadillo Domain Proteins*/genetics , Armadillo Domain Proteins*/metabolism , Cytoskeletal Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Action Potentials*/physiology , Action Potentials*/drug effects , Sciatic Nerve*/injuries , Sciatic Neuropathy*/physiopathology , Sciatic Neuropathy*/pathology , Muscle, Skeletal*/physiopathology, Animals ; Mice ; Mice, Knockout ; Mice, Inbred C57BL ; Male ; Axons/pathology

β-Adrenergic Receptor Activation Modulates the Induction of Complex Spike-Dependent LTP by Regulating Multiple Forms of Heterosynaptic Plasticity.

Autoren: O'Dell TJ; Department of Physiology, David Geffen School of Medicine, and Integrative Center for Learning and Memory, Brain Research Institute, University of California, Los Angeles, California, USA.

Quelle: Hippocampus [Hippocampus] 2025 Nov; Vol. 35 (6), pp. e70043.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: United States NLM ID: 9108167 Publication Model: Print Cited Medium: Internet ISSN: 1098-1063 (Electronic) Linking ISSN: 10509631 NLM ISO Abbreviation: Hippocampus Subsets: MEDLINE

MeSH-Schlagworte: Long-Term Potentiation*/physiology , Long-Term Potentiation*/drug effects , Receptors, Adrenergic, beta*/metabolism , CA1 Region, Hippocampal*/physiology , CA1 Region, Hippocampal*/drug effects , Neuronal Plasticity*/physiology , Neuronal Plasticity*/drug effects , Synapses*/physiology , Synapses*/drug effects , Action Potentials*/physiology , Action Potentials*/drug effects, Animals ; Male ; Mice, Inbred C57BL ; Mice ; Adrenergic beta-Agonists/pharmacology ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Electric Stimulation ; Hippocampus/physiology ; Hippocampus/drug effects

Ephaptic Coupling Contributes to the Propagation of Paroxysmal Depolarization Shifts In Vitro .

Autoren: Kritskaya KA Gaidin SG Kosenkov AM et al.

Quelle: Brain connectivity [Brain Connect] 2025 Nov-Dec; Vol. 15 (9-10), pp. 339-350. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101550313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2158-0022 (Electronic) Linking ISSN: 21580014 NLM ISO Abbreviation: Brain Connect Subsets: MEDLINE

MeSH-Schlagworte: Hippocampus*/physiology , Hippocampus*/drug effects , Hippocampus*/cytology , Neurons*/physiology , Neurons*/drug effects , Membrane Potentials*/physiology , Membrane Potentials*/drug effects , Action Potentials*/physiology , Action Potentials*/drug effects, Animals ; Patch-Clamp Techniques ; Cells, Cultured ; Rats ; Calcium Channel Blockers/pharmacology ; Neuroglia/physiology ; Neuroglia/drug effects

In vivo magnetic recording of single-neuron action potentials.

Autoren: Klein FJ Jendritza P Chopin C et al.

Quelle: Journal of neurophysiology [J Neurophysiol] 2025 Oct 01; Vol. 134 (4), pp. 1306-1319. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

MeSH-Schlagworte: Action Potentials*/physiology , Neurons*/physiology , Magnetoencephalography*/methods , Magnetoencephalography*/instrumentation, Animals ; Male ; Rats ; Magnetic Fields

Discovery and Treatment of Action Potential-Independent Myotonia in Hyperkalemic Periodic Paralysis.

Autoren: Dupont C Deardorff A Nawaz M et al.

Quelle: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2025 Oct; Vol. 12 (10), pp. 2056-2067. Date of Electronic Publication: 2025 Jul 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2328-9503 (Electronic) Linking ISSN: 23289503 NLM ISO Abbreviation: Ann Clin Transl Neurol Subsets: MEDLINE

MeSH-Schlagworte: Action Potentials*/physiology , Action Potentials*/drug effects , Paralysis, Hyperkalemic Periodic*/physiopathology , Paralysis, Hyperkalemic Periodic*/complications , Paralysis, Hyperkalemic Periodic*/drug therapy , Myotonia*/physiopathology , Myotonia*/drug therapy , Myotonia*/etiology , Dantrolene*/pharmacology, Animals ; Mice ; Disease Models, Animal ; Calcium/metabolism ; Muscle, Skeletal/physiopathology ; Muscle, Skeletal/drug effects ; Muscle Contraction/drug effects ; Muscle Contraction/physiology ; Male ; Muscle Relaxants, Central/pharmacology

Persistent Na ⁺ and M-type K ⁺ currents opposingly control spike gain in CA3 pyramidal cells.

Autoren: Tamir I Yaari Y

Quelle: Neurobiology of disease [Neurobiol Dis] 2025 Oct 01; Vol. 214, pp. 107034. Date of Electronic Publication: 2025 Jul 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

MeSH-Schlagworte: Pyramidal Cells*/physiology , Pyramidal Cells*/drug effects , Pyramidal Cells*/metabolism , CA3 Region, Hippocampal*/physiology , CA3 Region, Hippocampal*/drug effects , CA3 Region, Hippocampal*/cytology , Action Potentials*/physiology , Action Potentials*/drug effects , Sodium Channels*/metabolism , Sodium Channels*/physiology, Animals ; Rats ; Male ; Riluzole/pharmacology ; Rats, Sprague-Dawley ; Anthracenes/pharmacology ; Patch-Clamp Techniques ; Phenylenediamines/pharmacology ; Carbamates/pharmacology

Voltage sensor interaction site for a selective small molecule Nav1.1 sodium channel potentiator that enhances firing of fast-spiking interneurons.

Autoren: Gallucci A Potet F Santos S et al.

Quelle: Molecular pharmacology [Mol Pharmacol] 2025 Oct; Vol. 107 (10), pp. 100072. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: NAV1.1 Voltage-Gated Sodium Channel*/metabolism , NAV1.1 Voltage-Gated Sodium Channel*/genetics , NAV1.1 Voltage-Gated Sodium Channel*/chemistry , Interneurons*/drug effects , Interneurons*/metabolism , Interneurons*/physiology , Action Potentials*/drug effects , Action Potentials*/physiology, Animals ; Humans ; Mice ; HEK293 Cells ; Mice, Inbred C57BL

The electrogenicity of the Na ⁺ /K ⁺ -ATPase poses challenges for computation in highly active spiking cells.

Autoren: Weerdmeester L Schleimer JH Schreiber S

Quelle: ELife [Elife] 2025 Dec 03; Vol. 14. Date of Electronic Publication: 2025 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Sodium-Potassium-Exchanging ATPase*/metabolism , Action Potentials* , Electric Fish*/physiology , Neurons*/physiology, Animals

Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings.

Autoren: Ye Z Shelton AM Shaker JR et al.

Quelle: Neuron [Neuron] 2025 Dec 03; Vol. 113 (23), pp. 3966-3982.e12. Date of Electronic Publication: 2025 Sep 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

MeSH-Schlagworte: Neurons*/physiology , Visual Cortex*/physiology , Visual Cortex*/cytology , Action Potentials*/physiology, Animals ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Silicon

ZEUS: Numerical methods to detect quasi-particles describing excitable media.

Autoren: Gobeyn A Kabus D Tolkacheva EG et al.

Quelle: Chaos (Woodbury, N.Y.) [Chaos] 2025 Dec 01; Vol. 35 (12).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Institute of Physics Country of Publication: United States NLM ID: 100971574 Publication Model: Print Cited Medium: Internet ISSN: 1089-7682 (Electronic) Linking ISSN: 10541500 NLM ISO Abbreviation: Chaos Subsets: MEDLINE

MeSH-Schlagworte: Algorithms* , Models, Cardiovascular* , Action Potentials* , Heart Conduction System*/physiopathology , Nonlinear Dynamics*, Animals ; Rabbits ; Computer Simulation ; Tachycardia, Ventricular/physiopathology

LatenZy : nonparametric, binning-free estimation of latencies from neural spiking data.

Autoren: Haak R Heimel JA

Quelle: Journal of neurophysiology [J Neurophysiol] 2025 Dec 01; Vol. 134 (6), pp. 1953-1968. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

MeSH-Schlagworte: Visual Cortex*/physiology , Neurons*/physiology , Action Potentials*/physiology , Reaction Time*/physiology, Animals ; Mice

Decoding natural visual scenes via learnable representations of neural spiking sequences.

Autoren: Peng J Jia S Zhang J et al.

Quelle: Neural networks : the official journal of the International Neural Network Society [Neural Netw] 2025 Dec; Vol. 192, pp. 107863. Date of Electronic Publication: 2025 Jul 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: United States NLM ID: 8805018 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2782 (Electronic) Linking ISSN: 08936080 NLM ISO Abbreviation: Neural Netw Subsets: MEDLINE

MeSH-Schlagworte: Action Potentials*/physiology , Neural Networks, Computer* , Visual Perception*/physiology , Neurons*/physiology , Learning*/physiology, Photic Stimulation/methods ; Animals ; Models, Neurological ; Wavelet Analysis ; Brain-Computer Interfaces ; Humans