Suchergebnisse - "ACTIN"

Twinfilin modulates tissue contractility through uncapping of capping protein in C. elegans.

Autoren: Saini A Kreizman S Towsif E et al.

Quelle: Development (Cambridge, England) [Development] 2025 Dec 01; Vol. 152 (23). Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

MeSH-Schlagworte: Caenorhabditis elegans*/metabolism , Caenorhabditis elegans*/embryology , Caenorhabditis elegans*/genetics , Caenorhabditis elegans Proteins*/metabolism , Caenorhabditis elegans Proteins*/genetics , Microfilament Proteins*/metabolism , Microfilament Proteins*/genetics , Actin Capping Proteins*/metabolism , Muscle Contraction*/physiology, Animals ; Actin Cytoskeleton/metabolism ; Actomyosin/metabolism ; Actins/metabolism

PIF4 controls autophagy during hypocotyl response to elevated ambient temperatures via ArpC5 in Arabidopsis.

Autoren: Pan Q Luo L Li J

Quelle: Developmental cell [Dev Cell] 2025 Dec 01; Vol. 60 (23), pp. 3236-3249.e4. Date of Electronic Publication: 2025 Jul 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE

MeSH-Schlagworte: Arabidopsis*/metabolism , Arabidopsis*/genetics , Arabidopsis*/growth & development , Arabidopsis Proteins*/metabolism , Arabidopsis Proteins*/genetics , Autophagy*/physiology , Hypocotyl*/metabolism , Hypocotyl*/growth & development , Basic Helix-Loop-Helix Transcription Factors*/metabolism , Basic Helix-Loop-Helix Transcription Factors*/genetics , Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/genetics, Gene Expression Regulation, Plant ; Autophagy-Related Protein 8 Family/metabolism ; Autophagy-Related Protein 8 Family/genetics ; Actin Cytoskeleton/metabolism ; Actins/metabolism ; Indoleacetic Acids/metabolism ; Autophagosomes/metabolism

Mechanism of Arp2/3 complex branch disassembly by human Coro7.

Autoren: Shatery Nejad N Boczkowska M Hilal R et al.

Quelle: Nature communications [Nat Commun] 2025 Nov 06; Vol. 16 (1), pp. 9809. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/chemistry , Actin-Related Protein 2-3 Complex*/genetics , Microfilament Proteins*/metabolism , Microfilament Proteins*/genetics , Microfilament Proteins*/chemistry, Humans ; Cryoelectron Microscopy ; Golgi Apparatus/metabolism ; Actin-Related Protein 3/metabolism ; Actin-Related Protein 3/chemistry ; Protein Binding ; Endoplasmic Reticulum/metabolism ; Actins/metabolism ; Protein Domains ; HeLa Cells ; 4-Butyrolactone/analogs & derivatives

Arp2/3-mediated bidirectional actin assembly by SPIN90 dimers.

Autoren: Liu T Cao L Mladenov M et al.

Quelle: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Nov; Vol. 32 (11), pp. 2262-2271. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/chemistry , Actins*/metabolism , Actins*/chemistry, Humans ; Protein Multimerization ; Actin Cytoskeleton/metabolism ; Actin Cytoskeleton/chemistry ; Models, Molecular ; Protein Binding ; Crystallography, X-Ray

Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease.

Autoren: Rogg M Weißer L Maier JI et al.

Quelle: Science advances [Sci Adv] 2025 Nov 28; Vol. 11 (48), pp. eady1623. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

MeSH-Schlagworte: Cilia*/metabolism , Cilia*/pathology , Epithelial Cells*/metabolism , Epithelial Cells*/pathology , Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/genetics , Kidney Tubules, Distal*/metabolism , Kidney Tubules, Distal*/pathology , Kidney Diseases*/metabolism , Kidney Diseases*/pathology , Kidney Diseases*/genetics, Animals ; Mice ; Humans ; Disease Models, Animal ; Mice, Knockout ; Actin Cytoskeleton/metabolism

Peri-mitochondrial actin filaments inhibit Parkin assembly by disrupting ER-mitochondria contacts.

Autoren: Fung TS Ghosh A Zavala MR et al.

Quelle: EMBO reports [EMBO Rep] 2025 Oct; Vol. 26 (20), pp. 4977-5008. Date of Electronic Publication: 2025 Aug 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH-Schlagworte: Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Mitochondria*/metabolism , Endoplasmic Reticulum*/metabolism , Actin Cytoskeleton*/metabolism , Actins*/metabolism, Humans ; Mitophagy ; Actin-Related Protein 2-3 Complex/metabolism ; Protein Kinases/metabolism ; HeLa Cells ; Microtubule-Associated Proteins/metabolism

Cardiac CapZ Regulation During Acute Exercise in Female Mice.

Autoren: Townsend LK Wright D Pyle WG

Quelle: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Aug 31; Vol. 39 (16), pp. e70950.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH-Schlagworte: Physical Conditioning, Animal*/physiology , CapZ Actin Capping Protein*/metabolism , CapZ Actin Capping Protein*/genetics , Myocardium*/metabolism , Myocytes, Cardiac*/metabolism, Animals ; Female ; Mice ; Mice, Transgenic ; Phosphorylation ; Myofibrils/metabolism ; Swimming/physiology ; Actin Cytoskeleton/metabolism

Arp2/3-complex regulation - Novel insights and open questions.

Autoren: Stradal TEB Boiero Sanders M Bieling P

Quelle: Current opinion in cell biology [Curr Opin Cell Biol] 2025 Aug; Vol. 95, pp. 102565. Date of Electronic Publication: 2025 Jun 25.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 8913428 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0410 (Electronic) Linking ISSN: 09550674 NLM ISO Abbreviation: Curr Opin Cell Biol Subsets: MEDLINE

MeSH-Schlagworte: Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/chemistry, Humans ; Animals ; Actin Cytoskeleton/metabolism

Optogenetic actin network assembly on lipid bilayer uncovers the network density-dependent functions of actin-binding proteins.

Autoren: Yamamoto K Miyazaki M

Quelle: Nature communications [Nat Commun] 2025 Aug 26; Vol. 16 (1), pp. 7583. Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Actins*/metabolism , Lipid Bilayers*/metabolism , Optogenetics*/methods , Actin Cytoskeleton*/metabolism, Animals ; Dogs ; Actin Depolymerizing Factors/metabolism ; Madin Darby Canine Kidney Cells ; Myosins/metabolism

Nuclear protein FNBP4: A novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics.

Autoren: Das S Maity A Maiti S

Quelle: The Journal of biological chemistry [J Biol Chem] 2025 Jun; Vol. 301 (6), pp. 108550. Date of Electronic Publication: 2025 Apr 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

MeSH-Schlagworte: Actin Cytoskeleton*/metabolism , Actin Cytoskeleton*/genetics , Nuclear Proteins*/metabolism , Nuclear Proteins*/genetics , Carrier Proteins*/metabolism , Carrier Proteins*/genetics , Microfilament Proteins*/metabolism , Microfilament Proteins*/genetics, Humans ; Formins ; CapZ Actin Capping Protein/metabolism ; CapZ Actin Capping Protein/genetics ; Animals ; Protein Binding

Crystal structure of Anopheles gambiae actin depolymerizing factor explains high affinity to monomeric actin.

Autoren: Lasiwa D Kursula I

Quelle: The FEBS journal [FEBS J] 2025 May; Vol. 292 (9), pp. 2381-2397. Date of Electronic Publication: 2025 Feb 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

MeSH-Schlagworte: Anopheles*/metabolism , Anopheles*/chemistry , Anopheles*/genetics , Actins*/metabolism , Actins*/chemistry , Insect Proteins*/chemistry , Insect Proteins*/metabolism , Insect Proteins*/genetics , Actin Depolymerizing Factors*/chemistry , Actin Depolymerizing Factors*/metabolism , Actin Depolymerizing Factors*/genetics, Animals ; Crystallography, X-Ray ; Protein Binding ; Binding Sites ; Models, Molecular ; Amino Acid Sequence ; Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/chemistry ; Actin Cytoskeleton/metabolism ; Adenosine Diphosphate/metabolism ; Adenosine Diphosphate/chemistry

Molecular mechanism of Arp2/3 complex activation by nucleation-promoting factors and an actin monomer.

Autoren: Sridharan Iyer S Wu J Pollard TD et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Mar 11; Vol. 122 (10), pp. e2421467122. Date of Electronic Publication: 2025 Mar 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/chemistry , Actins*/metabolism , Actins*/chemistry , Wiskott-Aldrich Syndrome Protein, Neuronal*/metabolism , Wiskott-Aldrich Syndrome Protein, Neuronal*/chemistry, Molecular Dynamics Simulation ; Humans ; Protein Binding ; Binding Sites ; Animals ; Actin-Related Protein 3/metabolism ; Actin-Related Protein 3/chemistry ; Actin Cytoskeleton/metabolism ; Protein Conformation

Mitochondria- and ER-associated actin are required for mitochondrial fusion.

Autoren: Gatti P Schiavon C Cicero J et al.

Quelle: Nature communications [Nat Commun] 2025 Jan 07; Vol. 16 (1), pp. 451. Date of Electronic Publication: 2025 Jan 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Mitochondrial Dynamics* , Actins*/metabolism , Mitochondria*/metabolism , Endoplasmic Reticulum*/metabolism , Mitochondrial Proteins*/metabolism , Mitochondrial Proteins*/genetics , Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/genetics, Animals ; Mice ; GTP Phosphohydrolases/metabolism ; GTP Phosphohydrolases/genetics ; Humans ; Formins/metabolism ; Formins/genetics ; Microfilament Proteins/metabolism ; Microfilament Proteins/genetics ; Actin Cytoskeleton/metabolism ; Dynamins/metabolism ; Dynamins/genetics

Reconstitution of Arp2/3-nucleated actin assembly with proteins CP, V-1, and CARMIL.

Autoren: Mooren OL McConnell P DeBrecht JD et al.

Quelle: Current biology : CB [Curr Biol] 2024 Nov 18; Vol. 34 (22), pp. 5173-5186.e4. Date of Electronic Publication: 2024 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: England NLM ID: 9107782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0445 (Electronic) Linking ISSN: 09609822 NLM ISO Abbreviation: Curr Biol Subsets: MEDLINE

MeSH-Schlagworte: Actin-Related Protein 2-3 Complex*/metabolism , Actins*/metabolism , Microfilament Proteins*/metabolism , Actin Capping Proteins*/metabolism, Animals ; Actin Cytoskeleton/metabolism ; Angiopoietin-Like Protein 2/metabolism ; Carrier Proteins/metabolism ; Rabbits ; Glia Maturation Factor/metabolism ; Glia Maturation Factor/genetics ; Protein Binding ; Humans ; Intercellular Signaling Peptides and Proteins

The Rac1-PAK1-Arp2/3 signaling axis regulates CHIKV nsP1-induced filopodia and optimal viral genome replication.

Autoren: Aïqui-Reboul-Paviet O Bakhache W Bernard E et al.

Quelle: Journal of virology [J Virol] 2024 Oct 22; Vol. 98 (10), pp. e0061224. Date of Electronic Publication: 2024 Sep 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

MeSH-Schlagworte: Virus Replication* , rac1 GTP-Binding Protein*/metabolism , rac1 GTP-Binding Protein*/genetics , p21-Activated Kinases*/metabolism , p21-Activated Kinases*/genetics , Chikungunya virus*/physiology , Chikungunya virus*/genetics , Signal Transduction* , Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/genetics , Pseudopodia*/metabolism , Pseudopodia*/virology, Humans ; Animals ; Viral Nonstructural Proteins/metabolism ; Viral Nonstructural Proteins/genetics ; Genome, Viral ; Cell Membrane/metabolism ; Cell Membrane/virology ; Cell Line ; Chlorocebus aethiops ; Host-Pathogen Interactions ; Actin-Related Protein 2/metabolism ; Actin-Related Protein 2/genetics

Choreography of rapid actin filament disassembly by coronin, cofilin, and AIP1.

Autoren: Oosterheert W Boiero Sanders M Hofnagel O et al.

Quelle: Cell [Cell] 2025 Nov 26; Vol. 188 (24), pp. 6845-6860.e27. Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

MeSH-Schlagworte: Actin Cytoskeleton*/metabolism , Actin Cytoskeleton*/ultrastructure , Actin Cytoskeleton*/chemistry , Microfilament Proteins*/metabolism , Microfilament Proteins*/chemistry , Actin Depolymerizing Factors*/metabolism , Actin Depolymerizing Factors*/chemistry, Cryoelectron Microscopy ; Actins/metabolism ; Animals ; Protein Binding ; Humans ; 4-Butyrolactone/analogs & derivatives

Vinculin-Arp2/3 interaction inhibits branched actin assembly to control migration and proliferation.

Autoren: James J Fokin AI Guschin DY et al.

Quelle: Life science alliance [Life Sci Alliance] 2024 Nov 15; Vol. 8 (2). Date of Electronic Publication: 2024 Nov 15 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE

MeSH-Schlagworte: Vinculin*/metabolism , Actin-Related Protein 2-3 Complex*/metabolism , Actins*/metabolism , Cell Movement* , Cell Proliferation*, Humans ; Actin Cytoskeleton/metabolism ; Cell Adhesion ; Protein Binding ; Cell Line

Deciphering the actin structure-dependent preferential cooperative binding of cofilin.

Autoren: Ngo KX Vu HT Umeda K et al.

Quelle: ELife [Elife] 2024 Aug 02; Vol. 13. Date of Electronic Publication: 2024 Aug 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Actins*/metabolism , Actins*/chemistry , Actin Depolymerizing Factors*/metabolism , Actin Depolymerizing Factors*/chemistry , Protein Binding*, Microscopy, Atomic Force ; Actin Cytoskeleton/metabolism ; Actin Cytoskeleton/chemistry ; Protein Conformation ; Models, Molecular ; Animals

Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells.

Autoren: Meyer NP Singh T Kutys ML et al.

Quelle: ELife [Elife] 2024 Sep 25; Vol. 13. Date of Electronic Publication: 2024 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Human Embryonic Stem Cells*/metabolism , Actin-Related Protein 2-3 Complex*/metabolism , Actin-Related Protein 2-3 Complex*/genetics , YAP-Signaling Proteins*/metabolism , Transcription Factors*/metabolism , Transcription Factors*/genetics, Humans ; Adaptor Proteins, Signal Transducing/metabolism ; Adaptor Proteins, Signal Transducing/genetics ; Actin Cytoskeleton/metabolism ; Cell Nucleus/metabolism ; Signal Transduction ; Pluripotent Stem Cells/metabolism ; Pluripotent Stem Cells/physiology

Reaching the full potential of cryo-EM reconstructions with molecular dynamics simulations at 310 K: Actin filaments as an example.

Autoren: Sridharan Iyer S Herman KM Paul T et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Dec 02; Vol. 122 (48), pp. e2521421122. Date of Electronic Publication: 2025 Nov 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Cryoelectron Microscopy*/methods , Molecular Dynamics Simulation* , Actin Cytoskeleton*/chemistry , Actin Cytoskeleton*/ultrastructure , Actin Cytoskeleton*/metabolism, Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/chemistry ; Adenosine Diphosphate/chemistry ; Adenosine Diphosphate/metabolism ; Actins/chemistry ; Temperature ; Protein Conformation