Suchergebnisse - "ABCC4"

Identification of Novel Biomarkers Associated with Corticosteroid Resistance in Asthma by Bioinformatics Analysis and Experimental Validation

Autoren: Xuan L Ren L Zhang W et al.

Quelle: Journal of Inflammation Research, Vol 18, Iss Issue 1, Pp 12379-12400 (2025)

Schlagwörter: Corticosteroid resistance, Asthma, TNS1, ABCC4, TNFRSF21, Macrophage, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

Dateibeschreibung: electronic resource

Relation: https://www.dovepress.com/identification-of-novel-biomarkers-associated-with-corticosteroid-resi-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Zugangs-URL: https://doaj.org/article/e260358fc5dc41f79512207779baee33

Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning.

Autoren: Nigam, Anisha Momper, Jeremiah Ojha, Anupam et al.

Quelle: Pharmaceutics. 16(5)

Schlagwörter: ABCC2, ABCC4, AI, SLC22A6, SLC22A8, SLCO1B1, SLCO1B3, drug transport, gut microbiome, hepatocyte, machine learning, organ crosstalk, proximal tubule

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/7nc0w5nk
https://escholarship.org/content/qt7nc0w5nk/qt7nc0w5nk.pdf

Structural basis of human ABCC4 recognition of cAMP and ligand recognition flexibility

Autoren: Xuepeng Wen Kaixue Si Dantong Zhu et al.

Quelle: Cell & Bioscience, Vol 15, Iss 1, Pp 1-19 (2025)

Schlagwörter: Structural biology, Cryo-EM, ABCC4, cAMP, 8-[Fluo]-cAMP, Transport, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2045-3701

Zugangs-URL: https://doaj.org/article/72648d3303194a4ea23c864048b607b7

ABCC4 rs3741206基因对慢性肾病患者阿托伐他汀代谢及降脂效果的影响 附视频

Quelle: Zhongguo shiyan zhenduanxue, Pp 549-553 (2024)

Schlagwörter: 阿托伐他汀, ABCC4, 基因多态性, 体内代谢, Pathology, RB1-214

Dateibeschreibung: electronic resource

Relation: http://ZSZD.publish.founderss.cn/thesisDetails?columnId=88417824&Fpath=home&index=0; https://doaj.org/toc/1007-4287

Zugangs-URL: https://doaj.org/article/c0536dbb42134ac5988b7db3034bd225

ABCC4 rs3741206基因对慢性肾病患者阿托伐他汀代谢及降脂效果的影响

Autoren: 鲁雨辰

Quelle: Zhongguo shiyan zhenduanxue, Vol 28, Pp 549-553 (2024)

Schlagwörter: 阿托伐他汀, ABCC4, 基因多态性, 体内代谢, Pathology, RB1-214

Dateibeschreibung: electronic resource

Relation: http://ZSZD.publish.founderss.cn/thesisDetails?columnId=88419741&Fpath=home&index=0; https://doaj.org/toc/1007-4287

Zugangs-URL: https://doaj.org/article/16e27dd5746847cf834db85eaa2fb02d

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

Autoren: Guiying Cui Kerry M. Strickland Analia J. Vazquez Cegla et al.

Quelle: Front Pharmacol
Frontiers in Pharmacology, Vol 15 (2024)

Schlagwörter: Pharmacology, 0301 basic medicine, human CFTR, Sf9 cell, 0303 health sciences, 03 medical and health sciences, baculovirus, lamprey CFTR, human ABCC4, Therapeutics. Pharmacology, RM1-950, ATPase activity

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38440176
https://doaj.org/article/b3cd1f4720734e46b9cde94ef7109c7e

The Biology and Biochemistry of Kynurenic Acid, a Potential Nutraceutical with Multiple Biological Effects

Autoren: Alves, Luana de Fátima Moore, J. Bernadette Kell, Douglas B.

Quelle: Alves , L D F , Moore , J B & Kell , D B 2024 , ' The Biology and Biochemistry of Kynurenic Acid, a Potential Nutraceutical with Multiple Biological Effects ' , International Journal of Molecular Sciences , vol. 25 , no. 16 , 9082 . https://doi.org/10.3390/ijms25169082

Schlagwörter: ABCC4, Cytoprotectant, Kynurenic acid, Nutraceutical, Oxidative stress, SLC22A6, SLC22A8

Dateibeschreibung: application/pdf

Verfügbarkeit: https://orbit.dtu.dk/en/publications/80dbab38-0620-4bc1-adf1-6747fa74deec
https://doi.org/10.3390/ijms25169082
https://backend.orbit.dtu.dk/ws/files/379858414/ijms-25-09082-v2.pdf

Pharmacokinetics of Tenofovir Alafenamide Fumarate and Tenofovir in the Chinese People: Effects of Non-Genetic Factors and Genetic Variations

Autoren: Li X Tan XY Cui XJ et al.

Quelle: Pharmacogenomics and Personalized Medicine, Vol 14, Pp 1315-1329 (2021)

Schlagwörter: tenofovir alafenamide fumarate, pharmacokinetics, slco1b3, abcb1, abcc2, abcc4, Therapeutics. Pharmacology, RM1-950

Dateibeschreibung: electronic resource

Relation: https://www.dovepress.com/pharmacokinetics-of-tenofovir-alafenamide-fumarate-and-tenofovir-in-th-peer-reviewed-fulltext-article-PGPM; https://doaj.org/toc/1178-7066

Zugangs-URL: https://doaj.org/article/a6b97824642044709bfe8bcad10615ad

Effect of polymorphisms in drug metabolism and transportation on plasma concentration of atorvastatin and its metabolites in patients with chronic kidney disease

Autoren: Zebin Jiang Zemin Wu Ruixue Liu et al.

Quelle: Front Pharmacol
Frontiers in Pharmacology, Vol 14 (2023)

Schlagwörter: Pharmacology, 0301 basic medicine, 03 medical and health sciences, drug-metabolizing enzymes, 0302 clinical medicine, plasma concentration, genetic polymorphism, atorvastatin, transporters, Therapeutics. Pharmacology, RM1-950, ABCC4, 3. Good health

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/36923356
https://doaj.org/article/b8677a7fba4343569ecfba41e9e48472

Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4

Autoren: Bloch, Magnus Raj, Isha Pape, Tillmann et al.

Quelle: Bloch , M , Raj , I , Pape , T & Taylor , N M I 2023 , ' Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4 ' , Structure , vol. 31 , no. 11 , pp. 1407-1418.e6 . https://doi.org/10.1016/j.str.2023.08.014

Schlagwörter: ABC transporter, ABCC4, cryo-EM, MRP4, multidrug resistance

Dateibeschreibung: application/pdf

Verfügbarkeit: https://researchprofiles.ku.dk/da/publications/5e415c85-e0b0-4d43-ad40-9b9e95a0f7e3
https://doi.org/10.1016/j.str.2023.08.014
https://curis.ku.dk/ws/files/373036524/1_s2.0_S0969212623002940_main.pdf

Characteristics of ABCC4 and ABCG2 High Expression Subpopulations in CRC—A New Opportunity to Predict Therapy Response

Autoren: Jakub Kryczka Joanna Boncela

Quelle: Cancers, Vol 15, Iss 23, p 5623 (2023)

Schlagwörter: ABCC4, ABCG2, CRC, immune cell infiltration, metastasis, CRC subpopulations, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.mdpi.com/2072-6694/15/23/5623; https://doaj.org/toc/2072-6694; https://doaj.org/article/739363071210433b9873df96404bdc48

Verfügbarkeit: https://doi.org/10.3390/cancers15235623
https://doaj.org/article/739363071210433b9873df96404bdc48

ABCC4 polymorphism indirectly reduces systemic exposure to a capecitabine metabolite 5'-deoxy-5-fluorouridine in Japanese subjects.

Autoren: Matsumoto, Natsumi Oishi, Ayano Yoshino, Shotaro et al.

Quelle: Br J Clin Pharmacol ; ISSN:1365-2125 ; Volume:91 ; Issue:11

Schlagwörter: ABCC4, capecitabine, cyclic adenosine monophosphate, pharmacokinetics, polymorphism, thymidine phosphorylase

Relation: https://doi.org/10.1002/bcp.70152; https://pubmed.ncbi.nlm.nih.gov/40588821

Verfügbarkeit: https://doi.org/10.1002/bcp.70152
https://pubmed.ncbi.nlm.nih.gov/40588821

Analysis of the regulation of drug uptake and detoxification systems in the blood cerebrospinal fluid barrier: the role of sex hormones and circadian rhythm

Autoren: Mineiro, Rafael Morais Paixão, Telma Alexandra Quintela Gonçalves, Isabel Maria Theriaga Mendes Varanda et al.

Weitere Verfasser: Mineiro, Rafael Morais Paixão, Telma Alexandra Quintela Gonçalves, Isabel Maria Theriaga Mendes Varanda et al.

Quelle: urn:tid:202544788

Schlagwörter: Abcc4, Hormonas Sexuais, Plexo Coroide, Ritmos Circadianos, Transportadores de Membrana

Dateibeschreibung: application/pdf

Verfügbarkeit: http://hdl.handle.net/10400.6/10536

Whole genome resequencing reveals an association of ABCC4 variants with preaxial polydactyly in pigs

Autoren: Cheng Ma Saber Khederzadeh Adeniyi C. Adeola et al.

Quelle: BMC Genomics, Vol 21, Iss 1, Pp 1-13 (2020)

Schlagwörter: Preaxial polydactyly, ABCC4, Ciliogenesis, Limb development, Whole-genome sequencing, Biotechnology, TP248.13-248.65, Genetics, QH426-470

Dateibeschreibung: electronic resource

Relation: http://link.springer.com/article/10.1186/s12864-020-6690-1; https://doaj.org/toc/1471-2164

Zugangs-URL: https://doaj.org/article/dc7b87220d2d47e9a94fd692d0745356

Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo‐optico‐neuropathy (SMON)

Autoren: Hideki Matsumoto Hideo Sasai Norio Kawamoto et al.

Quelle: Molecular Genetics & Genomic Medicine, Vol 10, Iss 1, Pp n/a-n/a (2022)

Schlagwörter: ABCC11, ABCC4, clioquinol, Japanese, subacute myelo‐optico‐neuropathy, Genetics, QH426-470

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2324-9269

Zugangs-URL: https://doaj.org/article/a9021fb27c00426580e01b32f6329e91

ABCC4 is regulated by microRNA-124a and microRNA-506

Autoren: Markova, Svetlana M Kroetz, Deanna L

Quelle: Biochemical Pharmacology. 87(3)

Schlagwörter: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Genetics, Kidney Disease, Biotechnology, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Computer Simulation, Gene Expression Regulation, HEK293 Cells, Haplotypes, Humans, Kidney, MicroRNAs, Models, Genetic, Multidrug Resistance-Associated Proteins, Polymorphism, Genetic, microRNA, Multidrug resistance associated protein, ABCC4, Polymorphism, (ATP-binding cassette transporter member C4), (monochlorobimane), (multidrug resistance protein member 4), MCB, MRP4, Polymorphism., Biochemistry and Cell Biology, Pharmacology & Pharmacy, Biochemistry and cell biology, Pharmacology and pharmaceutical sciences

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/5m11k5v7
https://escholarship.org/content/qt5m11k5v7/qt5m11k5v7.pdf

A novel molecular mechanism for a long non-coding RNA PCAT92 implicated in prostate cancer

Autoren: Bawa P. S. Ravi S. Paul S. et al.

Quelle: Oncotarget

Schlagwörter: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, ABCC4, lncRNA, PCAT92, Prostate cancer, ZIC2, Research Paper, 3. Good health

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.oncotarget.com/article/25940/pdf/
https://pubmed.ncbi.nlm.nih.gov/30197753
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126693/
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&%20path%5B%5D=25940
https://www.mendeley.com/catalogue/7d32b30b-510b-32f5-8d02-3b371583c196/
https://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=25940&path%5B%5D=80959

Variants in TPMT, ITPA, ABCC4 And ABCB1 Genes as Predictors of 6-Mercaptopurine Induced Toxicity in Children with Acute Lymphoblastic Leukemia

Autoren: George P. Patrinos Nikola Kotur Biljana Stankovic et al.

Quelle: J Med Biochem
Journal of Medical Biochemistry, Vol 37, Iss 3, Pp 320-327 (2018)

Schlagwörter: 0301 basic medicine, Original Paper, 0303 health sciences, 03 medical and health sciences, childhood acute lymphoblastic leukemia (all), tpmt, 6-mercaptopurine (6-mp), itpa, abcc4, QD415-436, abcb1, Biochemistry, 3. Good health

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/30598629
https://doaj.org/article/86d87a47397b4a4fac2b798a00971e7c
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298470
https://scindeks.ceon.rs/article.aspx?artid=1452-82581803320M
http://sciendo.com/article/10.1515/jomb-2017-0060
https://content.sciendo.com/view/journals/jomb/37/3/article-p320.xml
https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2018/1452-82581803320M.pdf
https://pubmed.ncbi.nlm.nih.gov/30598629/

Platelet Transcriptome Profiling in HIV and ATP-Binding Cassette Subfamily C Member 4 (ABCC4) as a Mediator of Platelet Activity

Autoren: Matthew Cambria Michael Cammer Nicole Allen et al.

Quelle: JACC Basic Transl Sci
JACC: Basic to Translational Science, Vol 3, Iss 1, Pp 9-22 (2018)

Schlagwörter: 0301 basic medicine, 03 medical and health sciences, 0302 clinical medicine, cardiovascular disease, RC666-701, CLINICAL RESEARCH, HIV, Diseases of the circulatory (Cardiovascular) system, platelet activity, ABCC4, 3. Good health

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/30062189
https://doaj.org/article/9806d582f68f4ac59f37e12d3ef724e9
https://core.ac.uk/display/153700231
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058944
https://basictranslational.onlinejacc.org/content/3/1/9
https://www.sciencedirect.com/science/article/pii/S2452302X17302796
https://pubmed.ncbi.nlm.nih.gov/30062189
https://www.jacc.org/doi/abs/10.1016/j.jacbts.2017.10.005

Polymorphisms in the CYP2A6 and ABCC4 genes are associated with a protective effect on chronic myeloid leukemia in the Brazilian Amazon population

Autoren: Natasha Monte Karla B. C. C. Pantoja Juliana C. G. Rodrigues et al.

Quelle: Molecular Genetics & Genomic Medicine, Vol 9, Iss 7, Pp n/a-n/a (2021)

Schlagwörter: ABCC4, ancestry, chronic myeloid leukemia, CYP2A6, genetic susceptibility, Genetics, QH426-470

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2324-9269

Zugangs-URL: https://doaj.org/article/3a00af5bb12d46e5b5cb8b08f7ea8310