Výsledky vyhľadávania - "1-Ring::Pyridines::Pyridones"

Perampanel: A therapeutic alternative in refractory status epilepticus associated with MELAS syndrome

Autori: Estevo Santamarina Alicia Alpuente Olga Maisterra a ďalší

Prispievatelia: Estevo Santamarina Alicia Alpuente Olga Maisterra a ďalší

Zdroj: Epilepsy Behav Case Rep
Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname
Epilepsy and Behavior Case Reports, Vol 11, Iss, Pp 92-95 (2019)

Predmety: Other subheadings::Other subheadings::Other subheadings::/drug therapy, Otros calificadores::Otros calificadores::Otros calificadores::/tratamiento farmacológico, DISEASES::Musculoskeletal Diseases::Muscular Diseases::Mitochondrial Myopathies::Mitochondrial Encephalomyopathies::MELAS Syndrome, Neurosciences. Biological psychiatry. Neuropsychiatry, Encefalitis - Tractament, Epilèpsia - Tractament, Piridina, Article, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, ENFERMEDADES::enfermedades musculoesqueléticas::enfermedades musculares::miopatías mitocondriales::encefalomiopatías mitocondriales::síndrome MELAS, DISEASES::Nervous System Diseases::Neurologic Manifestations::Seizures::Status Epilepticus, ENFERMEDADES::enfermedades del sistema nervioso::manifestaciones neurológicas::convulsiones::estado epiléptico, COMPUESTOS QUÍMICOS Y DROGAS::compuestos heterocíclicos::compuestos heterocíclicos de 1 anillo::piridinas::piridonas, CHEMICALS AND DRUGS::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyridines::Pyridones, RC321-571

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/30834194
https://hdl.handle.net/11351/4033
https://doaj.org/article/80cb1c00eb904ceebd53f4bc38952de9
https://www.sciencedirect.com/science/article/pii/S2213323218301695
https://pubmed.ncbi.nlm.nih.gov/30834194/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384302
https://www.ncbi.nlm.nih.gov/pubmed/30834194
https://europepmc.org/articles/PMC6384302

In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm

Autori: Artigas, Laura Coma, Mireia Matos-Filipe, Pedro a ďalší

Prispievatelia: Artigas, Laura Coma, Mireia Matos-Filipe, Pedro a ďalší

Predmety: Coronavirus infections, Infecciones por coronavirus, Antiviral agents, Melatonin, Combined modality therapy, Antivirales, Melatonina, Terapia combinada, Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents, Medical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections, Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Receptors, Cytoplasmic and Nuclear::Receptors, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Combined Modality Therapy, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Repositioning, Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyridines::Pyridones, Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Proprotein Convertases::Furin, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, Medical Subject Headings::Information Science::Information Science::Medical Informatics::Medical Informatics Applications::Information Systems::Databases as Topic::Databases, Factual::Databases, Pharmaceutical

Popis súboru: application/pdf

Relation: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0240149; Artigas L, Coma M, Matos-Filipe P, Aguirre-Plans J, Farrés J, Valls R. In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm. PLoS One. 2020 Oct 2;15(10):e0240149.; http://hdl.handle.net/10668/3220; PMC7531795

Dostupnosť: http://hdl.handle.net/10668/3220
https://doi.org/10.1371/journal.pone.0240149